| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Bono, C Balducci, P Richelmi, G F Koob, L Pulvirent. Dopamine partial receptor agonists reduce ethanol intake in the rat. European journal of pharmacology. vol 296. issue 3. 1997-03-12. PMID:8904074. |
the aim of the present study was to test the effects of systemic administration of terguride and sdz 208-911 (n-[(8 alpha)-2,6-dimethylergoline-8-yl]-2,2-diethylpropanamide), two prototype dopamine partial receptor agonists, in free-feeding, non-deprived rats trained to drink ethanol (10% w/v) and water in 'free-choice' limited access conditions. |
1997-03-12 |
2023-08-12 |
rat |
| G Bono, C Balducci, P Richelmi, G F Koob, L Pulvirent. Dopamine partial receptor agonists reduce ethanol intake in the rat. European journal of pharmacology. vol 296. issue 3. 1997-03-12. PMID:8904074. |
these results suggest that dopamine partial receptor agonists reduce the reinforcing properties of ethanol in the rat, an effect similar to that previously observed with cocaine. |
1997-03-12 |
2023-08-12 |
rat |
| N D Volkow, G J Wang, J S Fowler, J Logan, R Hitzemann, Y S Ding, N Pappas, C Shea, K Piscan. Decreases in dopamine receptors but not in dopamine transporters in alcoholics. Alcoholism, clinical and experimental research. vol 20. issue 9. 1997-03-12. PMID:8986209. |
it has been hypothesized that ethanol's actions on the dopamine (da) system may participate in addiction. |
1997-03-12 |
2023-08-12 |
Not clear |
| C W Hodge, A M Chappelle, H H Samso. Dopamine receptors in the medial prefrontal cortex influence ethanol and sucrose-reinforced responding. Alcoholism, clinical and experimental research. vol 20. issue 9. 1997-03-12. PMID:8986215. |
dopamine receptors in the medial prefrontal cortex influence ethanol and sucrose-reinforced responding. |
1997-03-12 |
2023-08-12 |
rat |
| C W Hodge, A M Chappelle, H H Samso. Dopamine receptors in the medial prefrontal cortex influence ethanol and sucrose-reinforced responding. Alcoholism, clinical and experimental research. vol 20. issue 9. 1997-03-12. PMID:8986215. |
this study tested the role of dopamine receptors in the medial prefrontal cortex (mpfc) in the onset, maintenance, and termination of ethanol and sucrose-reinforced responding. |
1997-03-12 |
2023-08-12 |
rat |
| R N Russell, W J McBride, L Lumeng, T K Li, J M Murph. Apomorphine and 7-OH DPAT reduce ethanol intake of P and HAD rats. Alcohol (Fayetteville, N.Y.). vol 13. issue 5. 1997-03-10. PMID:8888949. |
adult male rats of the alcohol-preferring (p) line (n = 10) and high alcohol drinking (had) line (n = 12) were used to study the effects of ip administration of 0.125-0.50 mg/kg 7-oh dpat (a putative d agonist) and 0.25-1.0 mg/kg apomorphine (a dopamine agonist with 50-fold higher affinities for the d1 and d2 receptors than for the d3 receptor) on the concurrent intakes of 10% (v/v) ethanol and 0.0125% (g/v) saccharin during a daily 4-h scheduled access period. |
1997-03-10 |
2023-08-12 |
rat |
| A D Campbell, R R Kohl, W J McBrid. Serotonin-3 receptor and ethanol-stimulated somatodendritic dopamine release. Alcohol (Fayetteville, N.Y.). vol 13. issue 6. 1997-02-27. PMID:8949951. |
administration of ethanol on the extracellular levels of dopamine (da) in the ventral tegmental area (vta) were studied using in vivo microdialysis. |
1997-02-27 |
2023-08-12 |
rat |
| K Fink, M Göther. Both ethanol and ifenprodil inhibit NMDA-evoked release of various neurotransmitters at different, yet proportional potency: potential relation to NMDA receptor subunit composition. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 3. 1997-02-18. PMID:8878061. |
irrespective of the brain region, ethanol was 2.6-5.1 times more potent in inhibiting the release of [3h]noradrenaline, [3h]5-hydroxytryptamine and [3h]gaba than the release of [3h]acetylcholine and [3h]dopamine. |
1997-02-18 |
2023-08-12 |
rat |
| K Fink, M Göther. Both ethanol and ifenprodil inhibit NMDA-evoked release of various neurotransmitters at different, yet proportional potency: potential relation to NMDA receptor subunit composition. Naunyn-Schmiedeberg's archives of pharmacology. vol 354. issue 3. 1997-02-18. PMID:8878061. |
in contrast, 100 nm ifenprodil did not affect the potency of ethanol in inhibiting [3h]dopamine and [3h]acetylcholine release in the corpus striatum. |
1997-02-18 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
the present study describes the effects of local perfusion with ethanol on extracellular dopamine and serotonin (5-hydroxytryptamine, 5-ht) concentrations in the ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
a significant and concentration-dependent increment in dialysate output of both dopamine and serotonin was observed after local infusion of ethanol. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
perfusion with ca(2+)-free medium or tetrodotoxin (1 microm in acsf) produced a significant reduction in basal extracellular dopamine and serotonin concentration but failed to block dopamine or serotonin release produced by infusion of 10% ethanol. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
perfusion with 100 mm k+ before and after infusion of 10% ethanol revealed that the second perfusion with high k+ solution still produced an increase in dopamine and serotonin concentration, similar in magnitude to the first response, indicating that perfusion with 10% ethanol did not cause irreversible damage to either dopamine cell bodies or serotonin terminals in the ventral tegmental area. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
these results suggest that dopamine and serotonin release from the ventral tegmental area produced by focal application of 10% ethanol is mediated, at least in part, by a non-exocytotic mechanism. |
1997-02-04 |
2023-08-12 |
rat |
| Q S Yan, M E Reith, P C Jobe, J W Daile. Focal ethanol elevates extracellular dopamine and serotonin concentrations in the rat ventral tegmental area. European journal of pharmacology. vol 301. issue 1-3. 1997-02-04. PMID:8773446. |
direct stimulation of the ventral tegmental area dopamine neurons by ethanol might be involved in the reinforcing properties of the drug. |
1997-02-04 |
2023-08-12 |
rat |
| J M Woods, M J Drus. Effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites. Journal of neurochemistry. vol 66. issue 5. 1997-01-14. PMID:8780050. |
effects of chronic ethanol consumption and aging on dopamine, serotonin, and metabolites. |
1997-01-14 |
2023-08-12 |
rat |
| N Wodarz, G A Wiesbeck, H Rommelspacher, P Riederer, J Bönin. Excretion of beta-carbolines harman and norharman in 24-hour urine of chronic alcoholics during withdrawal and controlled abstinence. Alcoholism, clinical and experimental research. vol 20. issue 4. 1996-12-27. PMID:8800388. |
animal experiments suggest that endogenous substances that could result from the interaction between neurotransmitters (dopamine and indoleamines) and ethanol and its metabolite acetaldehyde might be involved in the pathogenesis and maintenance of alcohol dependence. |
1996-12-27 |
2023-08-12 |
human |
| J H Kehne, H J Ketteler, T C McCloskey, C K Sullivan, M W Dudley, C J Schmid. Effects of the selective 5-HT2A receptor antagonist MDL 100,907 on MDMA-induced locomotor stimulation in rats. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 2. 1996-12-26. PMID:8840347. |
previous work demonstrated that mdma-stimulated dopamine release could be reduced by the selective 5-ht2a receptor antagonist [r-(+)-a- (2,3-dimethoxyphenyl)-1-[2-(4-fluorophenylethyl)]-4-piperidinem ethanol] (mdl 100,907). |
1996-12-26 |
2023-08-12 |
rat |
| A R Caggiula, S M Antelman, A M Palmer, S Kiss, D J Edwards, D Koca. The effects of ethanol on striatal dopamine and frontal cortical D-[3H]aspartate efflux oscillate with repeated treatment. Relevance to individual differences in drug responsiveness. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 15. issue 2. 1996-12-26. PMID:8840348. |
the effects of ethanol on striatal dopamine and frontal cortical d-[3h]aspartate efflux oscillate with repeated treatment. |
1996-12-26 |
2023-08-12 |
human |