| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
both ethanol intake and preference were reduced by a dopamine d1 receptor partial agonist, sfk 38393 ((+/-)-1-phenyl-2,3,4,5-tetrahydro-(1h)-3-benzazepine-7,8-diol hydrochloride), in a dose-dependent manner. |
1997-05-29 |
2023-08-12 |
rat |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
the dopamine d2/d3 receptor agonist 7-oh-dpat ((+/-)-7-hydroxy-n,n-(di-n-propyl-2-aminotetralin)) at the lowest dose of 0.01 mg/kg increased both ethanol intake and preference. |
1997-05-29 |
2023-08-12 |
rat |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
the dopamine d1 receptor antagonist sch 23390 (r-(+)-7-chloro-2,3,4,5-tetrahydro-3-methyl-1-phenyl-1h-3-benzazepine-8- ol), dopamine d2/d3 receptor antagonist raclopride and 5-ht2/d2 receptor antagonist risperidone did not affect ethanol consumption, although all at high doses induced a significant decrease in water intake, indicating a non-specific decrease in consummatory behavior with these compounds. |
1997-05-29 |
2023-08-12 |
rat |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
these results suggest the involvement of the dopaminergic system in ethanol intake and ethanol reinforcement with dopamine d1 and d2/d3 receptors playing opposing roles. |
1997-05-29 |
2023-08-12 |
rat |
| J S Silvestre, M F O'Neill, A G Fernandez, J M Palacio. Effects of a range of dopamine receptor agonists and antagonists on ethanol intake in the rat. European journal of pharmacology. vol 318. issue 2-3. 1997-05-29. PMID:9016913. |
blockade of dopamine d2 receptors had no selective effect on ethanol consumption and ethanol preference. |
1997-05-29 |
2023-08-12 |
rat |
| G Y Ng, B F O'Dowd, S R Georg. Genotypic differences in mesolimbic enkephalin gene expression in DBA/2J and C57BL/6J inbred mice. European journal of pharmacology. vol 311. issue 1. 1997-05-15. PMID:8884235. |
we conclude that functional connectivity exists between enkephalin and dopamine systems, and although low mesolimbic enkephalin may predispose to high ethanol preference, dopamine is a more important determinant than enkephalin in the hierarchy of neurotransmitter pathways that mediate the increased vulnerability for ethanol consumption in the c57 mouse. |
1997-05-15 |
2023-08-12 |
mouse |
| H J Yim, T Schallert, P K Randall, P M Bungay, R A Gonzale. Effect of ethanol on extracellular dopamine in rat striatum by direct perfusion with microdialysis. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084423. |
effect of ethanol on extracellular dopamine in rat striatum by direct perfusion with microdialysis. |
1997-04-28 |
2023-08-12 |
rat |
| H J Yim, T Schallert, P K Randall, P M Bungay, R A Gonzale. Effect of ethanol on extracellular dopamine in rat striatum by direct perfusion with microdialysis. Journal of neurochemistry. vol 68. issue 4. 1997-04-28. PMID:9084423. |
the concentration-related effects of ethanol on extracellular dopamine (da) in rat striatum were studied by direct perfusion through microdialysis probes in freely moving rats. |
1997-04-28 |
2023-08-12 |
rat |
| K Yoshimoto, K Yayama, Y Sorimachi, J Tani, M Ogata, A Nishimura, T Yoshida, S Ueda, S Komur. Possibility of 5-HT3 receptor involvement in alcohol dependence: a microdialysis study of nucleus accumbens dopamine and serotonin release in rats with chronic alcohol consumption. Alcoholism, clinical and experimental research. vol 20. issue 9 Suppl. 1997-04-09. PMID:8986229. |
in alcohol-treated rats, perfusion of 40 mm k+ and 100 mm ethanol (etoh) through the microdialysis probe increased the extracellular levels of acc dopamine (da), compared with controls. |
1997-04-09 |
2023-08-12 |
rat |
| K Kiianmaa, M Nurmi, J D Sinclai. Genetically determined influences on voluntary ethanol consumption: extracellular levels of ethanol and monoamines in the nucleus accumbens of the alcohol preferring AA and alcohol avoiding ANA rat lines. Alcohol and alcoholism (Oxford, Oxfordshire). Supplement. vol 2. 1997-04-07. PMID:8974319. |
ethanol (0.5, 1, or 2 g/kg ip) significantly increased the extracellular levels of dopamine, dopac, and hva, but not that of 5-hiaa, suggesting stimulation of dopamine release by ethanol. |
1997-04-07 |
2023-08-12 |
rat |
| O Blomqvist, M Ericson, D H Johnson, J A Engel, B Söderpal. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. European journal of pharmacology. vol 314. issue 3. 1997-04-03. PMID:8957244. |
it has been suggested that the mesolimbic dopamine activating and the reinforcing properties of ethanol involve activation of central nicotinic acetylcholine receptors. |
1997-04-03 |
2023-08-12 |
rat |
| O Blomqvist, M Ericson, D H Johnson, J A Engel, B Söderpal. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. European journal of pharmacology. vol 314. issue 3. 1997-04-03. PMID:8957244. |
dopamine release, as indicated by accumulation of 3-methoxytyramine after monoamine oxidase inhibition, was increased in the limbic forebrain (including the nucleus accumbens, the olfactory tubercles, the amygdala and the septum) after acute nicotine (0.35 mg/kg s.c.) or ethanol (2.5 g/kg i.p.) |
1997-04-03 |
2023-08-12 |
rat |
| O Blomqvist, M Ericson, D H Johnson, J A Engel, B Söderpal. Voluntary ethanol intake in the rat: effects of nicotinic acetylcholine receptor blockade or subchronic nicotine treatment. European journal of pharmacology. vol 314. issue 3. 1997-04-03. PMID:8957244. |
the present results further implicate central nicotinic receptors in the molecular events mediating the reinforcing properties of ethanol, and suggest that subchronic nicotine enhances the responsiveness of mesolimbic dopamine neurons both to nicotine and to ethanol. |
1997-04-03 |
2023-08-12 |
rat |
| M Nurmi, T Ashizawa, J D Sinclair, K Kiianma. Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats. European journal of pharmacology. vol 315. issue 3. 1997-03-26. PMID:8982665. |
effect of prior ethanol experience on dopamine overflow in accumbens of aa and ana rats. |
1997-03-26 |
2023-08-12 |
rat |
| M Nurmi, T Ashizawa, J D Sinclair, K Kiianma. Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats. European journal of pharmacology. vol 315. issue 3. 1997-03-26. PMID:8982665. |
the purpose of this study was to investigate the effect of repeated ethanol administration on dopamine overflow in the nucleus accumbens of alcohol-preferring aa (alko alcohol) and alcohol-avoiding ana (alko nonalcohol) rats. |
1997-03-26 |
2023-08-12 |
rat |
| M Nurmi, T Ashizawa, J D Sinclair, K Kiianma. Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats. European journal of pharmacology. vol 315. issue 3. 1997-03-26. PMID:8982665. |
dopamine is a possible mediator of the reinforcing effects of ethanol, but it has previously been shown that ethanol-naïve alcohol-preferring aa and alcohol-nonpreferring ana rats do not differ in their dopaminergic reaction to an intraperitoneal ethanol injection (0.5-2.0 g/kg), as assessed by measuring extracellular dopamine in the nucleus accumbens with in vivo microdialysis. |
1997-03-26 |
2023-08-12 |
rat |
| M Nurmi, T Ashizawa, J D Sinclair, K Kiianma. Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats. European journal of pharmacology. vol 315. issue 3. 1997-03-26. PMID:8982665. |
the group that had ingested the ethanol voluntarily showed, however, a significantly smaller increase in dopamine after 1 g/kg ethanol i.p. |
1997-03-26 |
2023-08-12 |
rat |
| M Nurmi, T Ashizawa, J D Sinclair, K Kiianma. Effect of prior ethanol experience on dopamine overflow in accumbens of AA and ANA rats. European journal of pharmacology. vol 315. issue 3. 1997-03-26. PMID:8982665. |
the hypothesis that dopamine mediates ethanol reinforcement in aa rats is not supported by the results. |
1997-03-26 |
2023-08-12 |
rat |
| G Bono, C Balducci, P Richelmi, G F Koob, L Pulvirent. Dopamine partial receptor agonists reduce ethanol intake in the rat. European journal of pharmacology. vol 296. issue 3. 1997-03-12. PMID:8904074. |
dopamine partial receptor agonists reduce ethanol intake in the rat. |
1997-03-12 |
2023-08-12 |
rat |
| G Bono, C Balducci, P Richelmi, G F Koob, L Pulvirent. Dopamine partial receptor agonists reduce ethanol intake in the rat. European journal of pharmacology. vol 296. issue 3. 1997-03-12. PMID:8904074. |
dopamine neurotransmission is an important neuropharmacological component of ethanol reinforcement in rodents. |
1997-03-12 |
2023-08-12 |
rat |