| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| B Söderpalm, M Ericson, P Olausson, O Blomqvist, J A Enge. Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942035. |
this dopamine activation may be involved in mediating the positive reinforcing effects of ethanol. |
2001-01-03 |
2023-08-12 |
mouse |
| B Söderpalm, M Ericson, P Olausson, O Blomqvist, J A Enge. Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942035. |
the present article reviews a series of investigations aimed at investigating whether nachrs are involved in the dopamine activating and reinforcing properties of ethanol. |
2001-01-03 |
2023-08-12 |
mouse |
| B Söderpalm, M Ericson, P Olausson, O Blomqvist, J A Enge. Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942035. |
the results obtained indicate that central nachrs in the ventral tegmental area are involved in mediating the mesolimbic dopamine activating and reinforcing effects of ethanol. |
2001-01-03 |
2023-08-12 |
mouse |
| B Söderpalm, M Ericson, P Olausson, O Blomqvist, J A Enge. Nicotinic mechanisms involved in the dopamine activating and reinforcing properties of ethanol. Behavioural brain research. vol 113. issue 1-2. 2001-01-03. PMID:10942035. |
moreover, subchronic nicotine treatment enhances the reinforcing and dopamine activating properties of ethanol. |
2001-01-03 |
2023-08-12 |
mouse |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in pkcepsilon-deficient mice. |
2000-12-22 |
2023-08-12 |
mouse |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
in addition, multiple lines of evidence suggest that the mesoaccumbens dopamine reward system is critically involved in the rewarding and reinforcing effects of ethanol. |
2000-12-22 |
2023-08-12 |
mouse |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
in this study, we report that mice lacking the epsilon isoform of pkc (pkcepsilon) show reduced operant ethanol self-administration and an absence of ethanol-induced increase in extracellular dopamine levels in the nucleus accumbens. |
2000-12-22 |
2023-08-12 |
mouse |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
in vivo microdialysis experiments showed that, in contrast to wild-type mice, pkcepsilon null mice exhibited no change in extracellular levels of dopamine in the nucleus accumbens following acute administration of ethanol (1 and 2 g/kg i.p. |
2000-12-22 |
2023-08-12 |
mouse |
| M F Olive, K K Mehmert, R O Messing, C W Hodg. Reduced operant ethanol self-administration and in vivo mesolimbic dopamine responses to ethanol in PKCepsilon-deficient mice. The European journal of neuroscience. vol 12. issue 11. 2000-12-22. PMID:11069609. |
these data provide further evidence that increases in extracellular mesolimbic dopamine levels contribute to the reinforcing effects of ethanol, and indicate that pharmacological agents inhibiting pkcepsilon may be useful in the treatment of alcohol dependence. |
2000-12-22 |
2023-08-12 |
mouse |
| J M Boyce, F O Risinge. Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11033008. |
enhancement of ethanol reward by dopamine d3 receptor blockade. |
2000-12-21 |
2023-08-12 |
mouse |
| J M Boyce, F O Risinge. Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11033008. |
this experiment examined the influence of u-99194a, a dopamine d3 receptor antagonist, on ethanol's rewarding effect in a place conditioning paradigm. |
2000-12-21 |
2023-08-12 |
mouse |
| J M Boyce, F O Risinge. Enhancement of ethanol reward by dopamine D3 receptor blockade. Brain research. vol 880. issue 1-2. 2000-12-21. PMID:11033008. |
the results are consistent with the notion that dopamine d3 systems are important in the response to ethanol and further suggest that d3 receptor blockade increases ethanol reward. |
2000-12-21 |
2023-08-12 |
mouse |
| H Inou. Effects of naltrexone on the accumulation of L-3, 4-dihydroxyphenylalanine and 5-hydroxy-L-tryptophan and on the firing rate induced by acute ethanol administration. European journal of pharmacology. vol 406. issue 3. 2000-12-11. PMID:11040344. |
naltrexone resulted in a decrease in the dopaminergic neuronal firing rates activated by ethanol and eventually in a reduction of the dopamine synthesis induced by ethanol in the dorsal striatum and nucleus accumbens, but not in the cerebral cortex. |
2000-12-11 |
2023-08-12 |
rat |
| H Inou. Effects of naltrexone on the accumulation of L-3, 4-dihydroxyphenylalanine and 5-hydroxy-L-tryptophan and on the firing rate induced by acute ethanol administration. European journal of pharmacology. vol 406. issue 3. 2000-12-11. PMID:11040344. |
mesolimbic dopamine neurons were slightly more sensitive to ethanol and naltrexone than were nigrostriatal dopamine neurons. |
2000-12-11 |
2023-08-12 |
rat |
| L Holdstock, H de Wi. Effects of ethanol at four phases of the menstrual cycle. Psychopharmacology. vol 150. issue 4. 2000-11-30. PMID:10958078. |
ovarian hormones, such as estrogen (e) and progesterone (p), interact with neurotransmitters, such as dopamine and gamma-aminobutyric acid, which are thought to be important in mediating the effects of ethanol. |
2000-11-30 |
2023-08-12 |
Not clear |
| N K Kharchenk. [Aldehyde dehydrogenase activity and level of dopamine in certain sections of the brain of rats preferring and refusing ethanol]. Ukrains'kyi biokhimichnyi zhurnal (1999 ). vol 72. issue 1. 2000-11-08. PMID:10979563. |
[aldehyde dehydrogenase activity and level of dopamine in certain sections of the brain of rats preferring and refusing ethanol]. |
2000-11-08 |
2023-08-12 |
rat |
| H J Yim, D L Robinson, M L White, J N Jaworski, P K Randall, F E Lancaster, R A Gonzale. Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. Alcoholism, clinical and experimental research. vol 24. issue 6. 2000-11-07. PMID:10888065. |
dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. |
2000-11-07 |
2023-08-12 |
Not clear |
| H J Yim, D L Robinson, M L White, J N Jaworski, P K Randall, F E Lancaster, R A Gonzale. Dissociation between the time course of ethanol and extracellular dopamine concentrations in the nucleus accumbens after a single intraperitoneal injection. Alcoholism, clinical and experimental research. vol 24. issue 6. 2000-11-07. PMID:10888065. |
dopamine release in the nucleus accumbens has been linked to the reinforcing effects of ethanol, but the time course or relationship of this response to ethanol concentrations in the brain has not been studied. |
2000-11-07 |
2023-08-12 |
Not clear |
| E A Engleman, W J McBride, A A Wilber, S R Shaikh, R D Eha, L Lumeng, T K Li, J M Murph. Reverse microdialysis of a dopamine uptake inhibitor in the nucleus accumbens of alcohol-preferring rats: effects on dialysate dopamine levels and ethanol intake. Alcoholism, clinical and experimental research. vol 24. issue 6. 2000-11-07. PMID:10888067. |
reverse microdialysis of a dopamine uptake inhibitor in the nucleus accumbens of alcohol-preferring rats: effects on dialysate dopamine levels and ethanol intake. |
2000-11-07 |
2023-08-12 |
rat |
| E A Engleman, W J McBride, A A Wilber, S R Shaikh, R D Eha, L Lumeng, T K Li, J M Murph. Reverse microdialysis of a dopamine uptake inhibitor in the nucleus accumbens of alcohol-preferring rats: effects on dialysate dopamine levels and ethanol intake. Alcoholism, clinical and experimental research. vol 24. issue 6. 2000-11-07. PMID:10888067. |
the mesolimbic dopamine (da) system has been implicated in mediating the reinforcing actions of ethanol (etoh). |
2000-11-07 |
2023-08-12 |
rat |