| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| M S Brodie, C Pesold, S B Appe. Ethanol directly excites dopaminergic ventral tegmental area reward neurons. Alcoholism, clinical and experimental research. vol 23. issue 11. 1999-12-30. PMID:10591603. |
ethanol's rewarding properties result from its ability to excite dopaminergic cell bodies in the vta which results in increased dopamine release in the nucleus accumbens. |
1999-12-30 |
2023-08-12 |
Not clear |
| M S Cowen, A J Lawrenc. The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 7. 1999-12-21. PMID:10581642. |
innate differences in opioid or dopamine neurotransmission may enhance the abuse liability of ethanol, as indicated by animal and human studies. |
1999-12-21 |
2023-08-12 |
human |
| M S Cowen, A J Lawrenc. The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 7. 1999-12-21. PMID:10581642. |
however, ethanol may also stimulate the formation of opiate-like compounds, which could interact with opioid (or dopamine) receptors. |
1999-12-21 |
2023-08-12 |
human |
| M S Cowen, A J Lawrenc. The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 7. 1999-12-21. PMID:10581642. |
ethanol appears to facilitate dopamine release by increasing opioidergic activity, disinhibiting dopaminergic neurons (by inhibition of gabaergic neurotransmission) via mu-opioid receptors in the ventral tegmental area (vta) and delta-opioid receptors in the nucleus accumbens (nacc). |
1999-12-21 |
2023-08-12 |
human |
| M S Cowen, A J Lawrenc. The role of opioid-dopamine interactions in the induction and maintenance of ethanol consumption. Progress in neuro-psychopharmacology & biological psychiatry. vol 23. issue 7. 1999-12-21. PMID:10581642. |
mesolimbic dopamine release induced by ethanol consumption seems to indicate ethanol-related stimuli are important, focussing attention on and enabling learning of the stimuli. |
1999-12-21 |
2023-08-12 |
human |
| C Cohen, O Curet, G Perrault, D J Sange. Reduction of oral ethanol self-administration in rats by monoamine oxidase inhibitors. Pharmacology, biochemistry, and behavior. vol 64. issue 3. 1999-12-13. PMID:10548268. |
evidence for a role of dopamine and serotonin in the control of ethanol intake in animals suggests that monoamine oxidase (mao) inhibitors, which increase the synaptic availability of serotonin and dopamine by blocking their metabolism, might have efficacy in the treatment of alcohol dependence. |
1999-12-13 |
2023-08-12 |
mouse |
| C Cohen, O Curet, G Perrault, D J Sange. Reduction of oral ethanol self-administration in rats by monoamine oxidase inhibitors. Pharmacology, biochemistry, and behavior. vol 64. issue 3. 1999-12-13. PMID:10548268. |
in conclusion, the present results showing that several mao inhibitors decreased ethanol self-administration in rats are consistent with previous findings that synaptic levels of serotonin and dopamine play a critical role in the control of ethanol self-administration. |
1999-12-13 |
2023-08-12 |
mouse |
| P Szot, S S White, R C Veith, D D Rasmusse. Reduced gene expression for dopamine biosynthesis and transport in midbrain neurons of adult male rats exposed prenatally to ethanol. Alcoholism, clinical and experimental research. vol 23. issue 10. 1999-11-30. PMID:10549997. |
reduced gene expression for dopamine biosynthesis and transport in midbrain neurons of adult male rats exposed prenatally to ethanol. |
1999-11-30 |
2023-08-12 |
rat |
| Q S Ya. Extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis. Alcohol (Fayetteville, N.Y.). vol 19. issue 1. 1999-11-02. PMID:10487381. |
extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis. |
1999-11-02 |
2023-08-12 |
rat |
| Q S Ya. Extracellular dopamine and serotonin after ethanol monitored with 5-minute microdialysis. Alcohol (Fayetteville, N.Y.). vol 19. issue 1. 1999-11-02. PMID:10487381. |
in order to determine potential rapid changes in extracellular dopamine (da) and 5-hydroxytryptamine (serotonin, 5-ht) during the first 5-10 min after ethanol, intracerebral microdialysis coupled with microbore hplc was used. |
1999-11-02 |
2023-08-12 |
rat |
| M J Thrasher, P A Freeman, F O Risinge. Clozapine's effects on ethanol's motivational properties. Alcoholism, clinical and experimental research. vol 23. issue 8. 1999-10-26. PMID:10470981. |
although dopamine d1 and d2 receptors have been implicated in ethanol's motivational effects, little is known about the contribution of dopamine d4 receptors. |
1999-10-26 |
2023-08-12 |
Not clear |
| M J Thrasher, P A Freeman, F O Risinge. Clozapine's effects on ethanol's motivational properties. Alcoholism, clinical and experimental research. vol 23. issue 8. 1999-10-26. PMID:10470981. |
the present experiments examined the effects of clozapine, a dopamine d4 receptor antagonist, on ethanol's aversive, rewarding, stimulant, and reinforcing properties. |
1999-10-26 |
2023-08-12 |
Not clear |
| S Chen, Q Li, P M Carvey, K L. Analysis of 9-fluorenylmethyloxycarbonyl derivatives of catecholamines by high performance liquid chromatography, liquid chromatography/mass spectrometry and tandem mass spectrometry. Rapid communications in mass spectrometry : RCM. vol 13. issue 18. 1999-10-26. PMID:10482902. |
9-fluorenylmethyloxycarbonyl (fmoc) derivatives of catecholamines, including dopamine (da; 3,4-dihydroxyphenethylamine), norepinephrine (ne; 2-amino-1-(3,4-dihydroxyphenyl)ethanol) and epinephrine (epi; 1-phenyl-1-hydroxy-2-methylaminopropane) as well as 3, 4-dihydroxybenzylamine (dhba) have been analyzed using high performance liquid chromatography coupled to fluorometric detection and atmospheric pressure chemical ionization mass spectrometry at low femtomole levels. |
1999-10-26 |
2023-08-12 |
Not clear |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. |
1999-10-25 |
2023-08-12 |
rat |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
withdrawal from chronic ethanol intoxication is associated with a reduction of dopamine neurotransmission. |
1999-10-25 |
2023-08-12 |
rat |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
to assess the role of l-type calcium channels in the inhibition of the dopaminergic system in the withdrawal state, the effects of the dihydropyridine calcium channel antagonist nimodipine on the extracellular levels of dopamine were studied in the nucleus accumbens shell of awake rats 10 h after withdrawal from chronic ethanol intoxication. |
1999-10-25 |
2023-08-12 |
rat |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
it is suggested that overactivity of l-type calcium channels is involved in the mechanisms of dopamine depletion as well as in certain behavioural/neurological signs associated with ethanol withdrawal. |
1999-10-25 |
2023-08-12 |
rat |
| Z L Rossetti, D Isola, J De Vry, F Fadd. Effects of nimodipine on extracellular dopamine levels in the rat nucleus accumbens in ethanol withdrawal. Neuropharmacology. vol 38. issue 9. 1999-10-25. PMID:10471090. |
by restoring depleted dopamine levels, dihydropyridines might ameliorate the dysphoric symptoms of ethanol abstinence. |
1999-10-25 |
2023-08-12 |
rat |
| M R Gerasimov, C R Ashby, E L Gardner, M J Mills, J D Brodie, S L Dewe. Gamma-vinyl GABA inhibits methamphetamine, heroin, or ethanol-induced increases in nucleus accumbens dopamine. Synapse (New York, N.Y.). vol 34. issue 1. 1999-10-20. PMID:10459167. |
we examined the acute effect of the irreversible gaba-transaminase inhibitor, gamma-vinyl gaba (gvg, sabril((r)), vigabatrin((r))) on increases in nucleus accumbens (nac) dopamine (da) following acute administration of methamphetamine, heroin, or ethanol. |
1999-10-20 |
2023-08-12 |
Not clear |
| G J Flora, V K Khanna, P K Set. Changes in neurotransmitter receptors and neurobehavioral variables in rats co-exposed to lead and ethanol. Toxicology letters. vol 109. issue 1-2. 1999-10-14. PMID:10514029. |
the influence of lead (10 mg/kg) and ethanol (10% v/v, in drinking water) administration, either alone or in combination for 8 weeks was investigated on the uptake of lead in tissues, dopamine, benzodiazepine and cholinergic (muscarinic) receptors, motor activity, number of fighting episodes and several selected lead-sensitive biochemical indices in young rats. |
1999-10-14 |
2023-08-12 |
rat |