| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Minoru Narita, Miho Soma, Hiroko Tamaki, Michiko Narita, Tsutomu Suzuk. Intensification of the development of ethanol dependence in mice lacking dopamine D(3) receptor. Neuroscience letters. vol 324. issue 2. 2002-07-12. PMID:11988344. |
to examine the role of dopamine d3 receptors in the development of physical dependence on ethanol, two genotypes were chronically treated with 7% ethanol according to the liquid diet method. |
2002-07-12 |
2023-08-12 |
mouse |
| Minoru Narita, Miho Soma, Hiroko Tamaki, Michiko Narita, Tsutomu Suzuk. Intensification of the development of ethanol dependence in mice lacking dopamine D(3) receptor. Neuroscience letters. vol 324. issue 2. 2002-07-12. PMID:11988344. |
the present data suggest that the lack of dopamine d3 receptor genes in the mouse brain leads to the aggravation of the development of physical dependence on ethanol. |
2002-07-12 |
2023-08-12 |
mouse |
| R E Maldve, T A Zhang, K Ferrani-Kile, S S Schreiber, M J Lippmann, G L Snyder, A A Fienberg, S W Leslie, R A Gonzales, R A Morriset. DARPP-32 and regulation of the ethanol sensitivity of NMDA receptors in the nucleus accumbens. Nature neuroscience. vol 5. issue 7. 2002-07-12. PMID:12068305. |
here we investigate how dopaminergic inputs alter the ethanol sensitivity of nmda receptors in rats and mice and report that previous dopamine receptor-1 (d1) activation, culminating in dopamine and camp-regulated phosphoprotein-32 kd (darpp-32) and nmda receptor subunit-1 (nr1)-nmda receptor phosphorylation, strongly decreases ethanol inhibition of nmda responses. |
2002-07-12 |
2023-08-12 |
mouse |
| William J McBrid. Central nucleus of the amygdala and the effects of alcohol and alcohol-drinking behavior in rodents. Pharmacology, biochemistry, and behavior. vol 71. issue 3. 2002-05-28. PMID:11830185. |
microdialysis studies demonstrated that acute ethanol (2 g/kg) injection increased dopamine (da) and serotonin (5-ht) release in the cea. |
2002-05-28 |
2023-08-12 |
mouse |
| L A C Lucas, B A McMille. Differences in brain area concentrations of dopamine and serotonin in Myers' High Ethanol Preferring (mHEP) and outbred rats. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 3. 2002-05-23. PMID:11956951. |
differences in brain area concentrations of dopamine and serotonin in myers' high ethanol preferring (mhep) and outbred rats. |
2002-05-23 |
2023-08-12 |
rat |
| L A C Lucas, B A McMille. Differences in brain area concentrations of dopamine and serotonin in Myers' High Ethanol Preferring (mHEP) and outbred rats. Journal of neural transmission (Vienna, Austria : 1996). vol 109. issue 3. 2002-05-23. PMID:11956951. |
differences in basal concentrations of 5-hydroxytryptamine (5-ht) and dopamine (da) correlate with the consumption of ethanol in some ethanol-preferring rat lines. |
2002-05-23 |
2023-08-12 |
rat |
| M Foster Olive, Michelle A Nannini, Christine J Ou, Heather N Koenig, Clyde W Hodg. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology. vol 437. issue 1-2. 2002-04-24. PMID:11864639. |
effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. |
2002-04-24 |
2023-08-12 |
rat |
| M Foster Olive, Michelle A Nannini, Christine J Ou, Heather N Koenig, Clyde W Hodg. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology. vol 437. issue 1-2. 2002-04-24. PMID:11864639. |
the purpose of the present study was to determine the acute effects of the anticraving compound acamprosate (calcium acetylhomotaurinate) and the closely related compound homotaurine on ethanol intake and ethanol-stimulated dopamine release in the nucleus accumbens. |
2002-04-24 |
2023-08-12 |
rat |
| M Foster Olive, Michelle A Nannini, Christine J Ou, Heather N Koenig, Clyde W Hodg. Effects of acute acamprosate and homotaurine on ethanol intake and ethanol-stimulated mesolimbic dopamine release. European journal of pharmacology. vol 437. issue 1-2. 2002-04-24. PMID:11864639. |
these compounds also delayed or suppressed ethanol-stimulated increases in nucleus accumbens dopamine release, suggesting that acamprosate and homotaurine may reduce ethanol intake by interfering with the ability of ethanol to activate the mesolimbic dopamine reward system. |
2002-04-24 |
2023-08-12 |
rat |
| Paolo S D'Aquila, Alessandra T Peana, Olga Tanda, Gino Serr. Different sensitivity to the motor-stimulating effect of amphetamine in Sardinian alcohol-preferring and non-preferring rats. European journal of pharmacology. vol 435. issue 1. 2002-04-02. PMID:11790379. |
in the present study, we compared the motor-stimulating effect of amphetamine, which is mediated by the release of dopamine in the nucleus accumbens and in the corpus striatum in two lines of rats selectively bred for high and low ethanol preference, the sardinian alcohol-preferring (sp) and the sardinian alcohol-non-preferring (snp) rats, respectively. |
2002-04-02 |
2023-08-12 |
rat |
| Xiu Liu, Friedbert Weis. Reversal of ethanol-seeking behavior by D1 and D2 antagonists in an animal model of relapse: differences in antagonist potency in previously ethanol-dependent versus nondependent rats. The Journal of pharmacology and experimental therapeutics. vol 300. issue 3. 2002-03-28. PMID:11861794. |
mesocorticolimbic dopamine (da) transmission has been implicated in the consummatory and, more recently, the incentive-motivational aspect of ethanol's actions. |
2002-03-28 |
2023-08-12 |
rat |
| Miriam Melis, Rosana Camarini, Mark A Ungless, Antonello Bonc. Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 6. 2002-03-27. PMID:11896147. |
long-lasting potentiation of gabaergic synapses in dopamine neurons after a single in vivo ethanol exposure. |
2002-03-27 |
2023-08-12 |
mouse |
| Miriam Melis, Rosana Camarini, Mark A Ungless, Antonello Bonc. Long-lasting potentiation of GABAergic synapses in dopamine neurons after a single in vivo ethanol exposure. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 22. issue 6. 2002-03-27. PMID:11896147. |
the mesolimbic dopamine (da) system originating in the ventral tegmental area (vta) is involved in many drug-related behaviors, including ethanol self-administration. |
2002-03-27 |
2023-08-12 |
mouse |
| C P Bailey, M J O'Callaghan, A P Croft, S J Manley, H J Littl. Alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption. Neuropharmacology. vol 41. issue 8. 2002-03-26. PMID:11747903. |
alterations in mesolimbic dopamine function during the abstinence period following chronic ethanol consumption. |
2002-03-26 |
2023-08-12 |
Not clear |
| Maria Antonietta Casu, Giancarlo Colombo, Gian Luigi Gessa, Luca Pan. Reduced TH-immunoreactive fibers in the limbic system of Sardinian alcohol-preferring rats. Brain research. vol 924. issue 2. 2002-03-05. PMID:11750910. |
these results indicate a selective reduction of terminal innervation in the medial portion of the mesocorticolimbic da system in sp rats and suggest that the latter may consume larger amounts of ethanol, when compared with snp rats, to compensate for the deficiency of dopamine to produce an adequate level of reward. |
2002-03-05 |
2023-08-12 |
rat |
| N R Zahniser, S Doole. Chronic and acute regulation of Na+/Cl- -dependent neurotransmitter transporters: drugs, substrates, presynaptic receptors, and signaling systems. Pharmacology & therapeutics. vol 92. issue 1. 2002-03-04. PMID:11750035. |
transient alterations in norepinephrine transporter, dopamine transporter, serotonin transporter, and gat1 function and/or number occur in response to more acute manipulations, including membrane potential changes, substrate exposure, ethanol exposure, and presynaptic receptor activation/inhibition. |
2002-03-04 |
2023-08-12 |
Not clear |
| C L Czachowski, A M Chappell, H H Samso. Effects of raclopride in the nucleus accumbens on ethanol seeking and consumption. Alcoholism, clinical and experimental research. vol 25. issue 10. 2002-02-07. PMID:11696662. |
previous research that used a fixed-ratio schedule of responding maintained by the presentation of small dippers (0.1 ml) of ethanol demonstrated that the dopamine d2 antagonist, raclopride, decreased total responding for ethanol by both delaying the onset of responding and causing the early termination of lever-press behavior. |
2002-02-07 |
2023-08-12 |
Not clear |
| J L Enggasser, H de Wi. Haloperidol reduces stimulant and reinforcing effects of ethanol in social drinkers. Alcoholism, clinical and experimental research. vol 25. issue 10. 2002-02-07. PMID:11696664. |
despite abundant preclinical support for a role of dopamine (da) in the stimulant-like and reinforcing effects of ethanol, there have been few studies directly investigating this mechanism in human subjects. |
2002-02-07 |
2023-08-12 |
human |
| M Koistinen, P Tuomainen, P Hyytiä, K Kiianma. Naltrexone suppresses ethanol intake in 6-hydroxydopamine-treated rats. Alcoholism, clinical and experimental research. vol 25. issue 11. 2002-01-17. PMID:11707635. |
the suppressive effect of opioid antagonists, such as naltrexone, on ethanol intake has been suggested to be based on the interference with ethanol-induced stimulation of dopamine release in the nucleus accumbens. |
2002-01-17 |
2023-08-12 |
rat |
| M Koistinen, P Tuomainen, P Hyytiä, K Kiianma. Naltrexone suppresses ethanol intake in 6-hydroxydopamine-treated rats. Alcoholism, clinical and experimental research. vol 25. issue 11. 2002-01-17. PMID:11707635. |
the aim of this study was to determine whether reduction of dopamine innervation to the nucleus accumbens with the neurotoxin 6-hydroxydopamine (6-ohda) alters naltrexone-induced suppression of ethanol consumption. |
2002-01-17 |
2023-08-12 |
rat |