| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Fumiya Shinohara, Yuta Asaoka, Hironori Kamii, Masabumi Minami, Katsuyuki Kaned. Stress augments the rewarding memory of cocaine via the activation of brainstem-reward circuitry. Addiction biology. vol 24. issue 3. 2020-05-18. PMID:29480583. |
additionally, intra-ventral tegmental area (vta) microinjection of antagonists for the muscarinic acetylcholine, nicotinic acetylcholine or glutamate receptors attenuated the stress-induced enhancement of cocaine cpp. |
2020-05-18 |
2023-08-13 |
rat |
| Frank J Meye, Mariano Soiza-Reilly, Tamar Smit, Marco A Diana, Martin K Schwarz, Manuel Mamel. Author Correction: Shifted pallidal co-release of GABA and glutamate in habenula drives cocaine withdrawal and relapse. Nature neuroscience. vol 23. issue 4. 2020-04-20. PMID:32139892. |
author correction: shifted pallidal co-release of gaba and glutamate in habenula drives cocaine withdrawal and relapse. |
2020-04-20 |
2023-08-13 |
Not clear |
| Christina Gobin, Marek Schwend. The cognitive cost of reducing relapse to cocaine-seeking with mGlu5 allosteric modulators. Psychopharmacology. vol 237. issue 1. 2020-04-10. PMID:31446451. |
antagonism of metabotropic glutamate receptor 5 (mglu5) has been demonstrated to decrease cocaine-seeking but may also further compromise cognitive function in long-term cocaine users. |
2020-04-10 |
2023-08-13 |
Not clear |
| Matthew D Puhl, Rajeev I Desai, Shunsuke Takagi, Kendall T Presti, Michelle R Doyle, Rachel J Donahue, Samantha M Landino, Jack Bergman, William A Carlezon, Joseph T Coyl. N-Methyl-d-aspartate receptor co-agonist availability affects behavioral and neurochemical responses to cocaine: insights into comorbid schizophrenia and substance abuse. Addiction biology. vol 24. issue 1. 2020-04-02. PMID:29168271. |
together, these findings suggest that the impaired nmdar function and a consequent decrease in sensitivity to cocaine effects on behavior are mediated by blunted da and glutamate responses normally triggered by the drug. |
2020-04-02 |
2023-08-13 |
mouse |
| Rajesh Narendran, Savannah Tollefson, Michael L Himes, Jennifer Paris, Brian Lopresti, Roberto Ciccocioppo, N Scott Maso. Nociceptin Receptors Upregulated in Cocaine Use Disorder: A Positron Emission Tomography Imaging Study Using [ The American journal of psychiatry. vol 176. issue 6. 2019-12-30. PMID:31055968. |
it also inhibits the release of a wide array of neurotransmitters, including dopamine and glutamate, which allows for it to block the rewarding properties of cocaine. |
2019-12-30 |
2023-08-13 |
Not clear |
| B M Siemsen, C M Reichel, K C Leong, C Garcia-Keller, C D Gipson, S Spencer, J A McFaddin, K N Hooker, P W Kalivas, M D Scofiel. Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core. Neuroscience. vol 406. 2019-12-24. PMID:30926546. |
following 2-h cocaine or methamphetamine self-administration (sa) and extinction, rodents display decreased levels of basal glutamate in the nucleus accumbens core (nacore), which transitions to elevated glutamate levels during drug seeking. |
2019-12-24 |
2023-08-13 |
Not clear |
| B M Siemsen, C M Reichel, K C Leong, C Garcia-Keller, C D Gipson, S Spencer, J A McFaddin, K N Hooker, P W Kalivas, M D Scofiel. Effects of Methamphetamine Self-Administration and Extinction on Astrocyte Structure and Function in the Nucleus Accumbens Core. Neuroscience. vol 406. 2019-12-24. PMID:30926546. |
we hypothesized that, like cocaine, this glutamate 'overflow' during methamphetamine seeking arises via decreased expression of the astroglial glutamate transporter glt-1, and withdrawal of perisynaptic astroglial processes (paps) from synapses. |
2019-12-24 |
2023-08-13 |
Not clear |
| Gopakumar P. Panikka. Cocaine Addiction: Neurobiology and Related Current Research in Pharmacotherapy. Substance abuse. vol 20. issue 3. 2019-11-20. PMID:12511828. |
the vicissitudes in the dopamine theory of brain reward mechanisms, dopaminergic effects of cocaine, and emerging roles of gaba, serotonin, glutamate, and nitric oxide in cocaine addiction and its sequelae are discussed. |
2019-11-20 |
2023-08-12 |
Not clear |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
behavioral history of withdrawal influences regulation of cocaine seeking by glutamate re-uptake. |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
withdrawal from cocaine regulates expression of distinct glutamate re-uptake transporters in the nucleus accumbens (nac). |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
in this study, we examined the cumulative effect of glutamate re-uptake by multiple excitatory amino acid transporters (eaats) on drug-seeking at two different stages of withdrawal from self-administered cocaine. |
2019-11-20 |
2023-08-13 |
rat |
| Luyi Zhou, Haley Andersen, Adrian C Arreola, Jill R Turner, Pavel I Ortinsk. Behavioral History of Withdrawal Influences Regulation of Cocaine Seeking by Glutamate Re-Uptake. PloS one. vol 11. issue 9. 2019-11-20. PMID:27685834. |
these results indicate that behavioral history of withdrawal influences the effect of re-uptake mediated glutamate clearance on cocaine seeking. |
2019-11-20 |
2023-08-13 |
rat |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
effects of repeated cocaine administration on dopamine d1 receptor modulation of mesocorticolimbic gaba and glutamate transmission. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
the present report tested the hypothesis that daily injections of cocaine would enhance d1 receptor responsiveness by infusing the d1 receptor agonist skf 38393 into the mpfc and monitoring glutamate and/or gaba release in the mpfc, nucleus accumbens and vta of saline- and cocaine-pretreated animals using in vivo microdialysis. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
intra-mpfc skf 38393 had no effect on glutamate levels in animals 1 day after daily cocaine treatments, increased mpfc glutamate at 7 days of withdrawal and reverted to decreasing glutamate at 30 days of withdrawal. |
2019-11-04 |
2023-08-13 |
Not clear |
| Jeffery D Steketee, Kun Li. Effects of repeated cocaine administration on dopamine D1 receptor modulation of mesocorticolimbic GABA and glutamate transmission. Brain research. vol 1698. 2019-11-04. PMID:30075100. |
infusion of skf 38393 into the mpfc of animals previously exposed to cocaine increased and reduced glutamate release in the nucleus accumbens after 7 and 30 days of withdrawal, respectively and increased glutamate levels in the vta 7 and 30 days after daily cocaine injections. |
2019-11-04 |
2023-08-13 |
Not clear |
| Maria A De Luca, Matthew W Buczynski, Gaetano Di Chiar. Loren Parsons' contribution to addiction neurobiology. Addiction biology. vol 23. issue 6. 2019-10-07. PMID:29949237. |
larry also applied microdialysis to study gaba and glutamate's role in ethanol dependence and heroin reinforcement, providing in vivo evidence for a sensitization of corticotropin-releasing factor-dependent release of gaba in the central amygdala in withdrawal from chronic ethanol and for a reduction of gaba transmission in the ventral pallidum in heroin but not cocaine intravenous self-administration. |
2019-10-07 |
2023-08-13 |
Not clear |
| Xia Li, Xiao-Qing Peng, Chloe J Jordan, Jie Li, Guo-Hua Bi, Yi He, Hong-Ju Yang, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29487381. |
mglur5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a cb1 receptor mechanism. |
2019-09-23 |
2023-08-13 |
Not clear |
| Xia Li, Xiao-Qing Peng, Chloe J Jordan, Jie Li, Guo-Hua Bi, Yi He, Hong-Ju Yang, Hai-Ying Zhang, Eliot L Gardner, Zheng-Xiong X. mGluR5 antagonism inhibits cocaine reinforcement and relapse by elevation of extracellular glutamate in the nucleus accumbens via a CB1 receptor mechanism. Scientific reports. vol 8. issue 1. 2019-09-23. PMID:29487381. |
metabotropic glutamate receptor 5 (mglur5) antagonism inhibits cocaine self-administration and reinstatement of drug-seeking behavior. |
2019-09-23 |
2023-08-13 |
Not clear |
| Allison R Bechard, Peter U Hamor, Lizhen Wu, Marek Schwendt, Lori A Knacksted. The effects of clavulanic acid and amoxicillin on cue-primed reinstatement of cocaine seeking. Behavioral neuroscience. vol 133. issue 2. 2019-07-22. PMID:30714803. |
research using the cocaine self-administration and reinstatement animal model of relapse finds that the beta-lactam antibiotic, ceftriaxone, attenuates cocaine-primed reinstatement of cocaine seeking and upregulates two proteins that regulate glutamate release and reuptake (xct and glt-1, respectively) in the nucleus accumbens core (nac). |
2019-07-22 |
2023-08-13 |
rat |