| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J W Boja, R M McNeill, A H Lewin, P Abraham, F I Carroll, M J Kuha. Selective dopamine transporter inhibition by cocaine analogs. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482769. |
several isopropyl and phenyl esters of 3 beta-(4-substituted phenyl) tropan-2 beta-carboxylic acid analogs of cocaine are relatively more potent and selective than cocaine and some other compounds in inhibiting dopamine uptake. |
1993-02-16 |
2023-08-11 |
Not clear |
| H M Davies, E Saikali, T Sexton, S R Childer. Novel 2-substituted cocaine analogs: binding properties at dopamine transport sites in rat striatum. European journal of pharmacology. vol 244. issue 1. 1993-02-12. PMID:8420793. |
novel 2-substituted cocaine analogs: binding properties at dopamine transport sites in rat striatum. |
1993-02-12 |
2023-08-12 |
rat |
| M J Kaufman, B K Madra. Distribution of cocaine recognition sites in monkey brain: II. Ex vivo autoradiography with [3H]CFT and [125I]RTI-55. Synapse (New York, N.Y.). vol 12. issue 2. 1993-02-08. PMID:1481136. |
cft [win 35,428, 2 beta-carbomethoxy-3 beta-(4-fluorophenyl)tropane] and its 4-iodinated analog rti-55 have been proposed as imaging probes for cocaine recognition sites and for dopamine transporters. |
1993-02-08 |
2023-08-11 |
monkey |
| R B Rothman, N Grieg, A Kim, B R De Costa, K C Rice, F I Carroll, A Per. Cocaine and GBR12909 produce equivalent motoric responses at different occupancy of the dopamine transporter. Pharmacology, biochemistry, and behavior. vol 43. issue 4. 1993-02-01. PMID:1475296. |
cocaine and gbr12909 produce equivalent motoric responses at different occupancy of the dopamine transporter. |
1993-02-01 |
2023-08-11 |
rat |
| L H Parsons, C A Schad, J B Justic. Co-administration of the D2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine. Journal of neurochemistry. vol 60. issue 1. 1993-01-25. PMID:8417161. |
co-administration of the d2 antagonist pimozide inhibits up-regulation of dopamine release and uptake induced by repeated cocaine. |
1993-01-25 |
2023-08-12 |
rat |
| Y L Hurd, M Herkenha. Influence of a single injection of cocaine, amphetamine or GBR 12909 on mRNA expression of striatal neuropeptides. Brain research. Molecular brain research. vol 16. issue 1-2. 1993-01-11. PMID:1281257. |
of the drugs tested, the dopamine uptake inhibitory agents cocaine and gbr 12909 acutely elevated mrna levels of all three neuropeptides, while amphetamine elevated mrna levels of substance p only. |
1993-01-11 |
2023-08-11 |
Not clear |
| H R Kranzler, L O Baue. Bromocriptine and cocaine cue reactivity in cocaine-dependent patients. British journal of addiction. vol 87. issue 11. 1993-01-08. PMID:1458033. |
based on previous reports that bromocriptine, a postsynaptic dopamine agonist, reduced cocaine craving and prevented relapse in cocaine-dependent subjects, effects of the drug were evaluated in 20 cocaine-dependent males in an inpatient drug rehabilitation programme. |
1993-01-08 |
2023-08-11 |
human |
| H Zhang, T H Lee, E H Ellinwoo. The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine. Brain research. vol 594. issue 2. 1993-01-07. PMID:1450959. |
sensitivity of the nigral dopamine neurons to intravenous apomorphine was examined in rats pretreated with continuous cocaine or saline for two weeks. |
1993-01-07 |
2023-08-11 |
rat |
| H Zhang, T H Lee, E H Ellinwoo. The progressive changes of neuronal activities of the nigral dopaminergic neurons upon withdrawal from continuous infusion of cocaine. Brain research. vol 594. issue 2. 1993-01-07. PMID:1450959. |
in humans, an increased sensitivity of dopamine soma/dendritic autoreceptors may partly account for the symptomatology associated with the intermediate phase of withdrawal from cocaine binges. |
1993-01-07 |
2023-08-11 |
rat |
| K Batsche, M I Granoff, R Y Wan. 5-HT3 receptor antagonists fail to block the suppressant effect of cocaine on the firing rate of A10 dopamine neurons in the rat. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450916. |
5-ht3 receptor antagonists fail to block the suppressant effect of cocaine on the firing rate of a10 dopamine neurons in the rat. |
1993-01-06 |
2023-08-11 |
rat |
| K Batsche, M I Granoff, R Y Wan. 5-HT3 receptor antagonists fail to block the suppressant effect of cocaine on the firing rate of A10 dopamine neurons in the rat. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450916. |
in the present study, we have shown that cocaine is significantly more potent in suppressing the firing rate of dopamine cells in the ventral tegmental area (vta or a10) than in the substantia nigra pars compacta (snc or a9). |
1993-01-06 |
2023-08-11 |
rat |
| K Batsche, M I Granoff, R Y Wan. 5-HT3 receptor antagonists fail to block the suppressant effect of cocaine on the firing rate of A10 dopamine neurons in the rat. Brain research. vol 592. issue 1-2. 1993-01-06. PMID:1450916. |
we have also determined the ability of several 5-ht3 receptor antagonists to alter the electrophysiological response of a10 dopamine neurons in the rat to cocaine, as these compounds have been implicated in modulating the effects of drugs of abuse on the dopamine system. |
1993-01-06 |
2023-08-11 |
rat |
| F Weiss, A Markou, M T Lorang, G F Koo. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain research. vol 593. issue 2. 1993-01-06. PMID:1450939. |
basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. |
1993-01-06 |
2023-08-11 |
rat |
| F Weiss, A Markou, M T Lorang, G F Koo. Basal extracellular dopamine levels in the nucleus accumbens are decreased during cocaine withdrawal after unlimited-access self-administration. Brain research. vol 593. issue 2. 1993-01-06. PMID:1450939. |
the effects of withdrawal from cocaine on extracellular dopamine (da) levels in the nucleus accumbens (nac) were examined by intracranial microdialysis in awake rats after periods (9.5-21.75 h) of unlimited-access, intravenous cocaine self-administration. |
1993-01-06 |
2023-08-11 |
rat |
| J M Johns, L W Means, M J Means, B A McMille. Prenatal exposure to cocaine. I: Effects on gestation, development, and activity in Sprague-Dawley rats. Neurotoxicology and teratology. vol 14. issue 5. 1993-01-06. PMID:1454042. |
one group received subcutaneous injections of 15 mg/kg cocaine twice daily (cocaine-d); a second group received 15 mg/kg cocaine twice daily for two consecutive days at 5-day intervals (cocaine-i); a third group received normal saline twice daily (saline); and a fourth group received 1.5 mg/kg amfonelic acid (afa), a dopamine reuptake inhibitor, once daily. |
1993-01-06 |
2023-08-11 |
rat |
| J M Johns, L W Means, M J Means, B A McMille. Prenatal exposure to cocaine. I: Effects on gestation, development, and activity in Sprague-Dawley rats. Neurotoxicology and teratology. vol 14. issue 5. 1993-01-06. PMID:1454042. |
these effects did not occur in the offspring exposed to afa, a potent dopamine uptake inhibitor and cns stimulant which indicate that one or more other sites for cocaine action may combine for its effects on the developing fetus. |
1993-01-06 |
2023-08-11 |
rat |
| K M Johnson, J S Bergmann, A P Kozikowsk. Cocaine and dopamine differentially protect [3H]mazindol binding sites from alkylation by N-ethylmaleimide. European journal of pharmacology. vol 227. issue 4. 1992-12-30. PMID:1446711. |
cocaine and dopamine differentially protect [3h]mazindol binding sites from alkylation by n-ethylmaleimide. |
1992-12-30 |
2023-08-11 |
rat |
| K M Johnson, J S Bergmann, A P Kozikowsk. Cocaine and dopamine differentially protect [3H]mazindol binding sites from alkylation by N-ethylmaleimide. European journal of pharmacology. vol 227. issue 4. 1992-12-30. PMID:1446711. |
the binding of cocaine, d-amphetamine and dopamine to the site on the dopamine transporter labeled by [3h]mazindol was investigated in rat striatal membranes. |
1992-12-30 |
2023-08-11 |
rat |
| K M Johnson, J S Bergmann, A P Kozikowsk. Cocaine and dopamine differentially protect [3H]mazindol binding sites from alkylation by N-ethylmaleimide. European journal of pharmacology. vol 227. issue 4. 1992-12-30. PMID:1446711. |
the effect of 10 mm n-ethylmaleimide was completely prevented by cocaine (ec50 of 3 microm), but neither 300 microm dopamine nor d-amphetamine afforded any significant protection. |
1992-12-30 |
2023-08-11 |
rat |
| K M Johnson, J S Bergmann, A P Kozikowsk. Cocaine and dopamine differentially protect [3H]mazindol binding sites from alkylation by N-ethylmaleimide. European journal of pharmacology. vol 227. issue 4. 1992-12-30. PMID:1446711. |
on the other hand, high concentrations of cocaine, d-amphetamine and dopamine provided similar protection against inhibition by 0.1 mm n-ethylmaleimide. |
1992-12-30 |
2023-08-11 |
rat |