Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
M S Hooks, A C Colvin, J L Juncos, J B Justic. Individual differences in basal and cocaine-stimulated extracellular dopamine in the nucleus accumbens using quantitative microdialysis. Brain research. vol 587. issue 2. 1992-10-22. PMID:1525663. |
however, there were no difference in percent change in dopamine following cocaine. |
1992-10-22 |
2023-08-11 |
human |
R Kuczenski, D S Sega. Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine. The Journal of pharmacology and experimental therapeutics. vol 262. issue 3. 1992-10-22. PMID:1527715. |
differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine. |
1992-10-22 |
2023-08-11 |
Not clear |
R Kuczenski, D S Sega. Differential effects of amphetamine and dopamine uptake blockers (cocaine, nomifensine) on caudate and accumbens dialysate dopamine and 3-methoxytyramine. The Journal of pharmacology and experimental therapeutics. vol 262. issue 3. 1992-10-22. PMID:1527715. |
to test our hypothesis that the difference in transmitter response may derive, in part, from the degree to which released dopamine in the two regions is metabolized to 3-methoxytyramine, we compared the effects of amphetamine with the uptake blockers, nomifensine and cocaine, on caudate and accumbens dialysate concentrations of dopamine, its acid metabolites and 3-methoxytyramine. |
1992-10-22 |
2023-08-11 |
Not clear |
C A Moody, N A Frambes, L P Spea. Psychopharmacological responsiveness to the dopamine agonist quinpirole in normal weanlings and in weanling offspring exposed gestationally to cocaine. Psychopharmacology. vol 108. issue 3. 1992-10-15. PMID:1355920. |
psychopharmacological responsiveness to the dopamine agonist quinpirole in normal weanlings and in weanling offspring exposed gestationally to cocaine. |
1992-10-15 |
2023-08-11 |
rat |
E M Unterwald, J Horne-King, M J Kree. Chronic cocaine alters brain mu opioid receptors. Brain research. vol 584. issue 1-2. 1992-10-07. PMID:1325249. |
the possibility that dopamine may modulate the expression of opioid receptors was investigated by determining the effects of chronic cocaine administration on the density of mu opioid receptors. |
1992-10-07 |
2023-08-11 |
rat |
E M Unterwald, J Horne-King, M J Kree. Chronic cocaine alters brain mu opioid receptors. Brain research. vol 584. issue 1-2. 1992-10-07. PMID:1325249. |
these results demonstrate that mu opioid receptors undergo upregulation in response to chronic cocaine exposure and suggest that dopamine activity can regulate the expression of mu opioid receptors. |
1992-10-07 |
2023-08-11 |
rat |
R A Lefebvr. The inhibitory effect of dopamine on cat gastric smooth muscle. The Journal of pharmacy and pharmacology. vol 44. issue 4. 1992-10-02. PMID:1355546. |
the effect of dopamine was not influenced by the presence of cocaine or hydrocortisone. |
1992-10-02 |
2023-08-11 |
cat |
J W Boja, L Markham, A Patel, G Uhl, M J Kuha. Expression of a single dopamine transporter cDNA can confer two cocaine binding sites. Neuroreport. vol 3. issue 3. 1992-10-02. PMID:1515577. |
expression of a single dopamine transporter cdna can confer two cocaine binding sites. |
1992-10-02 |
2023-08-11 |
rat |
J W Boja, L Markham, A Patel, G Uhl, M J Kuha. Expression of a single dopamine transporter cDNA can confer two cocaine binding sites. Neuroreport. vol 3. issue 3. 1992-10-02. PMID:1515577. |
radiolabeled cocaine analogs can bind to low and high affinity sites on striatal dopamine transporters (dat). |
1992-10-02 |
2023-08-11 |
rat |
B A Sorg, J D Stekete. Mechanisms of cocaine-induced sensitization. Progress in neuro-psychopharmacology & biological psychiatry. vol 16. issue 6. 1992-09-30. PMID:1513927. |
repeated treatment with cocaine led to a blockade of the footshock-induced increase in extracellular dopamine in the medial prefrontal cortex. |
1992-09-30 |
2023-08-11 |
rat |
N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
it is also well established that the euphoric and rewarding responses evoked by drugs of addiction, such as amphetamine and cocaine, are mediated by central dopamine systems. |
1992-09-29 |
2023-08-11 |
Not clear |
N B Mercuri, P Calabresi, G Bernard. The electrophysiological actions of dopamine and dopaminergic drugs on neurons of the substantia nigra pars compacta and ventral tegmental area. Life sciences. vol 51. issue 10. 1992-09-29. PMID:1355254. |
in addition, substances which increase the release (amphetamine), the synthesis (levodopa) or block the uptake (cocaine, nomifensine, amineptine) of dopamine in the brain inhibit the firing activity of the dopaminergic cells throughout dopamine-mediated mechanisms. |
1992-09-29 |
2023-08-11 |
Not clear |
Y Minabe, C R Ashby, C Heyser, L P Spear, R Y Wan. The effects of prenatal cocaine exposure on spontaneously active midbrain dopamine neurons in adult male offspring: an electrophysiological study. Brain research. vol 586. issue 1. 1992-09-29. PMID:1511345. |
the effects of prenatal cocaine exposure on spontaneously active midbrain dopamine neurons in adult male offspring: an electrophysiological study. |
1992-09-29 |
2023-08-11 |
rat |
Y Minabe, C R Ashby, C Heyser, L P Spear, R Y Wan. The effects of prenatal cocaine exposure on spontaneously active midbrain dopamine neurons in adult male offspring: an electrophysiological study. Brain research. vol 586. issue 1. 1992-09-29. PMID:1511345. |
in this study, the technique of extracellular single unit recording was used to examine the effect of prenatal cocaine exposure on the number of spontaneously active dopamine (da) cells in the substantia nigra pars compacta (snc or a9) and the ventral tegmental area (vta or a10) of male sprague-dawley rats on postnatal days 56-68. |
1992-09-29 |
2023-08-11 |
rat |
G M Farfel, M S Kleven, W L Woolverton, L S Seiden, B D Perr. Effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey. Brain research. vol 578. issue 1-2. 1992-09-25. PMID:1380862. |
effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey. |
1992-09-25 |
2023-08-11 |
monkey |
G M Farfel, M S Kleven, W L Woolverton, L S Seiden, B D Perr. Effects of repeated injections of cocaine on catecholamine receptor binding sites, dopamine transporter binding sites and behavior in rhesus monkey. Brain research. vol 578. issue 1-2. 1992-09-25. PMID:1380862. |
the densities of dopamine d1 receptor binding sites, dopamine transporter binding sites and beta adrenergic receptor binding sites were significantly decreased in caudate nucleus to 51%, 17% and 61% of control, respectively, two weeks after repeated cocaine injections. |
1992-09-25 |
2023-08-11 |
monkey |
P A Broderic. Cocaine's colocalized effects on synaptic serotonin and dopamine in ventral tegmentum in a reinforcement paradigm. Pharmacology, biochemistry, and behavior. vol 42. issue 4. 1992-09-25. PMID:1513872. |
cocaine's colocalized effects on synaptic serotonin and dopamine in ventral tegmentum in a reinforcement paradigm. |
1992-09-25 |
2023-08-11 |
rat |
P A Broderic. Cocaine's colocalized effects on synaptic serotonin and dopamine in ventral tegmentum in a reinforcement paradigm. Pharmacology, biochemistry, and behavior. vol 42. issue 4. 1992-09-25. PMID:1513872. |
the effect of subcutaneous (sc) cocaine (20 mg/kg) on synaptic concentrations of the biogenic amines, dopamine (da), and serotonin (5-ht) in ventral tegmental area, (vta-[a10]) was studied in freely moving and behaving rats (rattus norvegicus) with in vivo voltammetry (in vivo electrochemistry). |
1992-09-25 |
2023-08-11 |
rat |
R D Mayfield, G Larson, N R Zahnise. Cocaine-induced behavioral sensitization and D1 dopamine receptor function in rat nucleus accumbens and striatum. Brain research. vol 573. issue 2. 1992-09-18. PMID:1387030. |
based on electrophysiological data showing that repeated cocaine administration produces persistent enhancement of d1 dopamine (da) receptor-mediated responses in nucleus accumbens (nac), we investigated whether changes in neurochemical properties of these receptors resulted when rats were injected with cocaine (15 mg/kg) for 6 days followed by a 7-day abstinence period. |
1992-09-18 |
2023-08-11 |
rat |
S Kitayama, S Shimada, H Xu, L Markham, D M Donovan, G R Uh. Dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. Proceedings of the National Academy of Sciences of the United States of America. vol 89. issue 16. 1992-09-15. PMID:1502198. |
dopamine transporter site-directed mutations differentially alter substrate transport and cocaine binding. |
1992-09-15 |
2023-08-11 |
Not clear |