| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J N Wilkin. Brain, lung, and cardiovascular interactions with cocaine and cocaine-induced catecholamine effects. Journal of addictive diseases. vol 11. issue 4. 1993-02-25. PMID:1336674. |
cocaine has been shown to alter circulating levels of the neurotransmitters, dopamine, norepinephrine, epinephrine, as well as the hypothalamic-pituitary-adrenal axis hormones corticotropin-releasing factor (crf), adrenocorticotropic hormone (acth), and cortisol. |
1993-02-25 |
2023-08-11 |
Not clear |
| G Elliso. Continuous amphetamine and cocaine have similar neurotoxic effects in lateral habenular nucleus and fasciculus retroflexus. Brain research. vol 598. issue 1-2. 1993-02-25. PMID:1486500. |
while continuously administered amphetamines, designed to mimic this intake pattern, have a neurotoxic effect on caudate dopamine terminals, several studies have failed to find similar effects following continuous cocaine. |
1993-02-25 |
2023-08-11 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
time course of extracellular dopamine and behavioral sensitization to cocaine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
using microdialysis in the ventral tegmental area and medial substantia nigra, the effect of repeated cocaine was examined on the extracellular levels of dopamine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
in contrast, 14 d after discontinuing daily cocaine, the increase in extracellular dopamine produced by an acute cocaine challenge was not augmented, although behavioral sensitization was present. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
one day after discontinuing daily treatments, the basal level of extracellular dopamine in the cocaine pretreated rats was significantly elevated over the level in saline-pretreated animals (1.3 nm vs. 0.8 nm). |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. II. Dopamine perikarya. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8380850. |
it is concluded that daily cocaine injections produce a transient alteration in the regulation of somatodendritic dopamine release. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
time course of extracellular dopamine and behavioral sensitization to cocaine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
twenty-four hours after discontinuing the low dose of daily cocaine, the increase in motor activity and extracellular dopamine elicited by an acute cocaine challenge was significantly elevated. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
in contrast, following the higher daily treatment regimen there was a significant augmentation in motor activity, but the increase in extracellular dopamine produced by cocaine was significantly reduced. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
when rats were challenged 10-14 d after discontinuing either dosage regimen of daily cocaine, the increase in both motor activity and extracellular dopamine was augmented. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
in general, the increase in extracellular dopamine by an acute cocaine challenge increased over time when rats were challenged between 1 and 22 d after discontinuing daily cocaine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
basal concentrations of extracellular dopamine were determined by measuring the in vivo flux of dopamine across the dialysis membrane, and there was no significant difference at 24 hr or 2 weeks following the last daily injection of saline or cocaine. |
1993-02-24 |
2023-08-12 |
rat |
| P W Kalivas, P Duff. Time course of extracellular dopamine and behavioral sensitization to cocaine. I. Dopamine axon terminals. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 13. issue 1. 1993-02-24. PMID:8423473. |
it is concluded that behavioral sensitization to cocaine is generally associated with an augmentation in extracellular dopamine in the ventral striatum, but that high doses of daily cocaine produce apparent tolerance to the augmentation in extracellular dopamine during the early withdrawal period. |
1993-02-24 |
2023-08-12 |
rat |
| J L Katz, J W Griffiths, L G Sharpe, E B De Souza, J M Witki. Cocaine tolerance and cross-tolerance. The Journal of pharmacology and experimental therapeutics. vol 264. issue 1. 1993-02-23. PMID:8093724. |
cross-tolerance was conferred to the close structural analog of cocaine, win 35,428, but not to another dopamine uptake inhibitor, gbr 12909. |
1993-02-23 |
2023-08-12 |
rat |
| J L Katz, J W Griffiths, L G Sharpe, E B De Souza, J M Witki. Cocaine tolerance and cross-tolerance. The Journal of pharmacology and experimental therapeutics. vol 264. issue 1. 1993-02-23. PMID:8093724. |
importantly, the tolerance produced by repeated administration of cocaine does not produce a cross-tolerance to gbr 12909, suggesting differences in mechanism among different structural forms of dopamine uptake inhibitors. |
1993-02-23 |
2023-08-12 |
rat |
| E K Richfiel. Zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex. Molecular pharmacology. vol 43. issue 1. 1993-02-23. PMID:8423763. |
zinc modulation of drug binding, cocaine affinity states, and dopamine uptake on the dopamine uptake complex. |
1993-02-23 |
2023-08-12 |
rat |
| U Scheffel, R F Dannals, D F Wong, F Yokoi, F I Carroll, M J Kuha. Dopamine transporter imaging with novel, selective cocaine analogs. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482766. |
dopamine transporter imaging with novel, selective cocaine analogs. |
1993-02-16 |
2023-08-11 |
Not clear |
| U Scheffel, R F Dannals, D F Wong, F Yokoi, F I Carroll, M J Kuha. Dopamine transporter imaging with novel, selective cocaine analogs. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482766. |
rti-121 and rti-122 are 3 beta-substituted phenyltropane analogs of cocaine that have high, selective binding affinity for dopamine transporters. |
1993-02-16 |
2023-08-11 |
Not clear |
| J W Boja, R M McNeill, A H Lewin, P Abraham, F I Carroll, M J Kuha. Selective dopamine transporter inhibition by cocaine analogs. Neuroreport. vol 3. issue 11. 1993-02-16. PMID:1482769. |
selective dopamine transporter inhibition by cocaine analogs. |
1993-02-16 |
2023-08-11 |
Not clear |