| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T B Borowski, L Kokkinidi. The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733202. |
the effects of cocaine, amphetamine, and the dopamine d1 receptor agonist skf 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. |
1999-03-09 |
2023-08-12 |
rat |
| T B Borowski, L Kokkinidi. The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733202. |
in experiment 1, acute administration of cocaine, amphetamine, and the dopamine (da) d1 receptor agonist skf 38393 produced a similar fear enhancement. |
1999-03-09 |
2023-08-12 |
rat |
| R Karler, L D Calder, D K Thai, J B Bedingfiel. The role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. Pharmacology, biochemistry, and behavior. vol 61. issue 4. 1999-03-01. PMID:9802839. |
the role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. |
1999-03-01 |
2023-08-12 |
mouse |
| R Karler, L D Calder, D K Thai, J B Bedingfiel. The role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. Pharmacology, biochemistry, and behavior. vol 61. issue 4. 1999-03-01. PMID:9802839. |
in previous studies we demonstrated that dopamine, specifically a d2-receptor system, in the frontal cortex of the mouse functions to inhibit the motor response elicited by systemically administered amphetamine or cocaine; the inhibition appears to be the result of the dopaminergic activation of a gabaergic system. |
1999-03-01 |
2023-08-12 |
mouse |
| K Grasing, S Ghos. Selegiline prevents long-term changes in dopamine efflux and stress immobility during the second and third weeks of abstinence following opiate withdrawal. Neuropharmacology. vol 37. issue 8. 1999-02-26. PMID:9833630. |
brain slices obtained from the nucleus accumbens of opiate-withdrawn animals immediately following swim stress testing displayed diminished efflux of tritiated dopamine after two in vitro exposures to cocaine or amphetamine. |
1999-02-26 |
2023-08-12 |
human |
| K Grasing, S Ghos. Selegiline prevents long-term changes in dopamine efflux and stress immobility during the second and third weeks of abstinence following opiate withdrawal. Neuropharmacology. vol 37. issue 8. 1999-02-26. PMID:9833630. |
cocaine increases neurotransmitter efflux through blockade of dopamine reuptake, while amphetamine augments efflux by stimulating release of dopamine from intracellular storage vesicles. |
1999-02-26 |
2023-08-12 |
human |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
effects of antipsychotics, vitamin e, and mk-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. |
1999-02-25 |
2023-08-12 |
rat |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
in addition to the potential value these findings have for further understanding cocaine abuse, it is proposed that the alteration in dopamine metabolism produced by cocaine, and the ability of haloperidol, clozapine and vitamin e to decrease cocaine's effects, model some biochemical aspects of schizophrenia. |
1999-02-25 |
2023-08-12 |
rat |
| N Chen, J B Justic. Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: kinetic analysis of inward and outward transport. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 24. 1999-02-25. PMID:9852563. |
the inhibition by cocaine of inward and outward transport of dopamine (da) at the cloned human norepinephrine transporter (hnet) and the relationship of the inhibitory patterns of cocaine to the conformational requirements of the transporter were investigated. |
1999-02-25 |
2023-08-12 |
human |
| A Y Deutch, M Bubser, C D Youn. Psychostimulant-induced Fos protein expression in the thalamic paraventricular nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 24. 1999-02-25. PMID:9852603. |
conversely, the effects of cocaine and amphetamine on pvt fos expression were blocked by pretreatment with the dopamine d2/3 antagonist raclopride. |
1999-02-25 |
2023-08-12 |
Not clear |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine d1 and d2 receptor-selective agonists: relevance to cocaine sensitization. |
1999-02-25 |
2023-08-12 |
rat |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
the mesoaccumbens dopamine (da) system is intricately involved in sensitization to the locomotor stimulant effects of cocaine. |
1999-02-25 |
2023-08-12 |
rat |
| K Y Little, L Zhang, T Desmond, K A Frey, G W Dalack, B J Cassi. Striatal dopaminergic abnormalities in human cocaine users. The American journal of psychiatry. vol 156. issue 2. 1999-02-25. PMID:9989560. |
previous human postmortem experiments have shown an abnormally high number of dopamine uptake sites in the striatum of chronic cocaine users, which might contribute to cocaine withdrawal symptoms such as depression and suicidality. |
1999-02-25 |
2023-08-12 |
human |
| R A Vaughan, G E Agoston, J R Lever, A H Newma. Differential binding of tropane-based photoaffinity ligands on the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 2. 1999-02-16. PMID:9880583. |
benztropine and its analogs are tropane ring-containing dopamine uptake inhibitors that produce behavioral effects markedly different from cocaine and other dopamine transporter blockers. |
1999-02-16 |
2023-08-12 |
Not clear |
| R A Vaughan, G E Agoston, J R Lever, A H Newma. Differential binding of tropane-based photoaffinity ligands on the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 2. 1999-02-16. PMID:9880583. |
the maps were compared with those obtained for dopamine transporters photoaffinity labeled with a gbr 12935 analog, [125i]1-[2-(diphenylmethoxy)ethyl]-4-[2-(4-azido-3-iodophenyl)ethy l]p iperazine ([125i]deep), and a cocaine analog, [125i]3beta-(p-chlorophenyl)tropane-2beta-carboxylic acid, 4'-azido-3'-iodophenylethyl ester ([125i]rti 82), which have been shown previously to interact with different regions of the primary sequence of the protein. |
1999-02-16 |
2023-08-12 |
Not clear |
| R A Vaughan, G E Agoston, J R Lever, A H Newma. Differential binding of tropane-based photoaffinity ligands on the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 2. 1999-02-16. PMID:9880583. |
thus, although benztropine and cocaine both contain tropane rings, their binding sites are distinct, suggesting that dopamine transport inhibition may occur by different mechanisms. |
1999-02-16 |
2023-08-12 |
Not clear |
| R A Vaughan, G E Agoston, J R Lever, A H Newma. Differential binding of tropane-based photoaffinity ligands on the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 2. 1999-02-16. PMID:9880583. |
these results support previously derived structure-activity relationships suggesting that benztropine and cocaine analogs bind to different domains on the dopamine transporter. |
1999-02-16 |
2023-08-12 |
Not clear |
| N D Volkow, G J Wang, J S Fowler, S J Gatley, J Logan, Y S Ding, S L Dewey, R Hitzemann, A N Gifford, N R Pappa. Blockade of striatal dopamine transporters by intravenous methylphenidate is not sufficient to induce self-reports of "high". The Journal of pharmacology and experimental therapeutics. vol 288. issue 1. 1999-02-05. PMID:9862747. |
the reinforcing effects of cocaine and methylphenidate have been linked to their ability to block dopamine transporters (dat). |
1999-02-05 |
2023-08-12 |
human |
| J L Katz, S Izenwasser, R H Kline, A C Allen, A H Newma. Novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine. The Journal of pharmacology and experimental therapeutics. vol 288. issue 1. 1999-02-05. PMID:9862785. |
novel 3alpha-diphenylmethoxytropane analogs: selective dopamine uptake inhibitors with behavioral effects distinct from those of cocaine. |
1999-02-05 |
2023-08-12 |
mouse |
| R S Mansbach, C C Rovetti, C S Freedlan. The role of monoamine neurotransmitter systems in the nicotine discriminative stimulus. Drug and alcohol dependence. vol 52. issue 2. 1999-02-04. PMID:9800142. |
the non-selective dopamine agonists amphetamine, cocaine and apomorphine produced partial substitution for nicotine, while the selective d2/d3 agonists bromocriptine and 7-oh-dpat and the dopamine autoreceptor antagonist (+)-aj-76 had little effect. |
1999-02-04 |
2023-08-12 |
rat |