| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| H K Wayment, H Deutsch, M M Schweri, J O Schen. Effects of methylphenidate analogues on phenethylamine substrates for the striatal dopamine transporter: potential as amphetamine antagonists? Journal of neurochemistry. vol 72. issue 3. 1999-03-18. PMID:10037500. |
methylphenidate (mpd) was found to inhibit competitively the striatal dopamine transporter (dat) and bind at sites on the dat in common with both cocaine (a non-substrate site ligand) and amphetamine (a substrate site ligand). |
1999-03-18 |
2023-08-12 |
Not clear |
| S Ikemoto, N E Goeder. Microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex. Brain research. vol 814. issue 1-2. 1999-03-16. PMID:9838097. |
microinjections of dopamine agonists and cocaine elevate plasma corticosterone: dissociation effects among the ventral and dorsal striatum and medial prefrontal cortex. |
1999-03-16 |
2023-08-12 |
rat |
| M E Alburges, G R Hanso. Differential responses by neurotensin systems in extrapyramidal and limbic structures to ibogaine and cocaine. Brain research. vol 818. issue 1. 1999-03-12. PMID:9914442. |
since previous studies demonstrated differential effects of psychotomimetic drugs (cocaine and methamphetamine) on neuropeptides such as neurotensin (nt), the present study was designed to determine: (1) the effects of ibogaine on striatal, nigral, cortical, and accumbens neurotensin-like immunoreactivity (ntli); (2) the effects of selective dopamine antagonists on ibogaine-induced changes in nt concentrations in these brain areas; and (3) the effects of ibogaine pretreatment on cocaine-induced changes in striatal, nigral, cortical and accumbens ntli content. |
1999-03-12 |
2023-08-12 |
Not clear |
| M C Caroleo, M Arbirio, P Di Francesco, L Pulvirenti, E Garaci, G Nistic. Cocaine induced T cell proliferation in the rat: role of amygdala dopamine D1 receptors. Neuroscience letters. vol 256. issue 2. 1999-03-10. PMID:9853703. |
cocaine induced t cell proliferation in the rat: role of amygdala dopamine d1 receptors. |
1999-03-10 |
2023-08-12 |
rat |
| M C Caroleo, M Arbirio, P Di Francesco, L Pulvirenti, E Garaci, G Nistic. Cocaine induced T cell proliferation in the rat: role of amygdala dopamine D1 receptors. Neuroscience letters. vol 256. issue 2. 1999-03-10. PMID:9853703. |
the increase of the proliferative response of splenocytes to con a was inhibited by coinfusion within the central amygdala of the dopamine d1 receptor antagonist sch 23390, together with cocaine, but not by coinfusion of the dopamine d2 receptor antagonist eticlopride. |
1999-03-10 |
2023-08-12 |
rat |
| M C Caroleo, M Arbirio, P Di Francesco, L Pulvirenti, E Garaci, G Nistic. Cocaine induced T cell proliferation in the rat: role of amygdala dopamine D1 receptors. Neuroscience letters. vol 256. issue 2. 1999-03-10. PMID:9853703. |
these results suggest that cocaine may produce at least some of its effects on the immune system through the activation of brain dopamine neurotransmission and that the central amygdala may represent a critical structure mediating cocaine-induced t cell proliferation. |
1999-03-10 |
2023-08-12 |
rat |
| T B Borowski, L Kokkinidi. The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733202. |
the effects of cocaine, amphetamine, and the dopamine d1 receptor agonist skf 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. |
1999-03-09 |
2023-08-12 |
rat |
| T B Borowski, L Kokkinidi. The effects of cocaine, amphetamine, and the dopamine D1 receptor agonist SKF 38393 on fear extinction as measured with potentiated startle: implications for psychomotor stimulant psychosis. Behavioral neuroscience. vol 112. issue 4. 1999-03-09. PMID:9733202. |
in experiment 1, acute administration of cocaine, amphetamine, and the dopamine (da) d1 receptor agonist skf 38393 produced a similar fear enhancement. |
1999-03-09 |
2023-08-12 |
rat |
| R Karler, L D Calder, D K Thai, J B Bedingfiel. The role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. Pharmacology, biochemistry, and behavior. vol 61. issue 4. 1999-03-01. PMID:9802839. |
the role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. |
1999-03-01 |
2023-08-12 |
mouse |
| R Karler, L D Calder, D K Thai, J B Bedingfiel. The role of dopamine in the mouse frontal cortex: a new hypothesis of behavioral sensitization to amphetamine and cocaine. Pharmacology, biochemistry, and behavior. vol 61. issue 4. 1999-03-01. PMID:9802839. |
in previous studies we demonstrated that dopamine, specifically a d2-receptor system, in the frontal cortex of the mouse functions to inhibit the motor response elicited by systemically administered amphetamine or cocaine; the inhibition appears to be the result of the dopaminergic activation of a gabaergic system. |
1999-03-01 |
2023-08-12 |
mouse |
| K Grasing, S Ghos. Selegiline prevents long-term changes in dopamine efflux and stress immobility during the second and third weeks of abstinence following opiate withdrawal. Neuropharmacology. vol 37. issue 8. 1999-02-26. PMID:9833630. |
brain slices obtained from the nucleus accumbens of opiate-withdrawn animals immediately following swim stress testing displayed diminished efflux of tritiated dopamine after two in vitro exposures to cocaine or amphetamine. |
1999-02-26 |
2023-08-12 |
human |
| K Grasing, S Ghos. Selegiline prevents long-term changes in dopamine efflux and stress immobility during the second and third weeks of abstinence following opiate withdrawal. Neuropharmacology. vol 37. issue 8. 1999-02-26. PMID:9833630. |
cocaine increases neurotransmitter efflux through blockade of dopamine reuptake, while amphetamine augments efflux by stimulating release of dopamine from intracellular storage vesicles. |
1999-02-26 |
2023-08-12 |
human |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
effects of antipsychotics, vitamin e, and mk-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. |
1999-02-25 |
2023-08-12 |
rat |
| R J Wyatt, F Karoum, J Masseran. Effects of antipsychotics, vitamin E, and MK-801 on dopamine dynamics in the rat brain following discontinuation of cocaine. Psychiatry research. vol 80. issue 3. 1999-02-25. PMID:9796937. |
in addition to the potential value these findings have for further understanding cocaine abuse, it is proposed that the alteration in dopamine metabolism produced by cocaine, and the ability of haloperidol, clozapine and vitamin e to decrease cocaine's effects, model some biochemical aspects of schizophrenia. |
1999-02-25 |
2023-08-12 |
rat |
| N Chen, J B Justic. Cocaine acts as an apparent competitive inhibitor at the outward-facing conformation of the human norepinephrine transporter: kinetic analysis of inward and outward transport. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 24. 1999-02-25. PMID:9852563. |
the inhibition by cocaine of inward and outward transport of dopamine (da) at the cloned human norepinephrine transporter (hnet) and the relationship of the inhibitory patterns of cocaine to the conformational requirements of the transporter were investigated. |
1999-02-25 |
2023-08-12 |
human |
| A Y Deutch, M Bubser, C D Youn. Psychostimulant-induced Fos protein expression in the thalamic paraventricular nucleus. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 18. issue 24. 1999-02-25. PMID:9852603. |
conversely, the effects of cocaine and amphetamine on pvt fos expression were blocked by pretreatment with the dopamine d2/3 antagonist raclopride. |
1999-02-25 |
2023-08-12 |
Not clear |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine d1 and d2 receptor-selective agonists: relevance to cocaine sensitization. |
1999-02-25 |
2023-08-12 |
rat |
| D J Henry, X T Hu, F J Whit. Adaptations in the mesoaccumbens dopamine system resulting from repeated administration of dopamine D1 and D2 receptor-selective agonists: relevance to cocaine sensitization. Psychopharmacology. vol 140. issue 2. 1999-02-25. PMID:9860115. |
the mesoaccumbens dopamine (da) system is intricately involved in sensitization to the locomotor stimulant effects of cocaine. |
1999-02-25 |
2023-08-12 |
rat |
| K Y Little, L Zhang, T Desmond, K A Frey, G W Dalack, B J Cassi. Striatal dopaminergic abnormalities in human cocaine users. The American journal of psychiatry. vol 156. issue 2. 1999-02-25. PMID:9989560. |
previous human postmortem experiments have shown an abnormally high number of dopamine uptake sites in the striatum of chronic cocaine users, which might contribute to cocaine withdrawal symptoms such as depression and suicidality. |
1999-02-25 |
2023-08-12 |
human |
| R A Vaughan, G E Agoston, J R Lever, A H Newma. Differential binding of tropane-based photoaffinity ligands on the dopamine transporter. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 19. issue 2. 1999-02-16. PMID:9880583. |
benztropine and its analogs are tropane ring-containing dopamine uptake inhibitors that produce behavioral effects markedly different from cocaine and other dopamine transporter blockers. |
1999-02-16 |
2023-08-12 |
Not clear |