| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David J Estrin, Julianna M Kulik, Nicholas J Beacher, Anthony P Pawlak, Samuel D Klein, Mark O Wes. Acquired Alterations in Nucleus Accumbens Responsiveness to a Cocaine-Paired Discriminative Stimulus Preceding Rats' Daily Cocaine Consumption. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664217. |
acquired alterations in nucleus accumbens responsiveness to a cocaine-paired discriminative stimulus preceding rats' daily cocaine consumption. |
2023-09-04 |
2023-09-07 |
rat |
| Mengfan Xia, Tanner A Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-09-02. PMID:37660129. |
voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. |
2023-09-02 |
2023-09-07 |
Not clear |
| Eleanor Blair Towers, Ivy L Williams, Emaan I Qillawala, Wendy J Lync. Role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. Frontiers in pharmacology. vol 14. 2023-08-11. PMID:37564182. |
role of nucleus accumbens dopamine 2 receptors in motivating cocaine use in male and female rats prior to and following the development of an addiction-like phenotype. |
2023-08-11 |
2023-08-16 |
human |
| Metika L Ngbokoli, Joaquin E Douton, Regina M Carell. Prelimbic cortex and nucleus accumbens core resting state signaling dynamics as a biomarker for cocaine seeking behaviors. Addiction neuroscience. vol 7. 2023-07-03. PMID:37396409. |
here, in vivo local field potential (lfp) electrophysiology was used in rats to examine the relationship between overall spontaneous (resting state) activity within the prelimbic cortex (prl) and nucleus accumbens (nac) core, and their functional connectivity, to cocaine taking and seeking behaviors. |
2023-07-03 |
2023-08-14 |
rat |
| Kyle D Ketchesin, Darius D Becker-Krail, Xiangning Xue, Rashaun S Wilson, TuKiet T Lam, Kenneth R Williams, Angus C Nairn, George C Tseng, Ryan W Loga. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. Journal of proteome research. 2023-06-13. PMID:37311105. |
differential effects of cocaine and morphine on the diurnal regulation of the mouse nucleus accumbens proteome. |
2023-06-13 |
2023-08-14 |
mouse |
| Madalyn Hafenbreidel, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Annika Tiller, Alice B Hall, Shayna Reed, Natasha Mayorga, Li Lin, Susan Khan, Michael D Cameron, Gavin Rumbaugh, Courtney A Mille. Basolateral Amygdala Corticotrophin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory. bioRxiv : the preprint server for biology. 2023-06-09. PMID:37292925. |
dorsal hippocampus [dphc], nucleus accumbens [nac]), nor does it interfere with associations for other aversive or appetitive stimuli, including cocaine (coc). |
2023-06-09 |
2023-08-14 |
Not clear |
| Vidhya Kumaresan, Yolpanhchana Lim, Poorva Juneja, Allison E Tipton, Giordano de Guglielmo, Lieselot L G Carrette, Marsida Kallupi, Lisa Maturin, Ying Liu, Olivier George, Huiping Zhan. Abstinence from Escalation of Cocaine Intake Changes the microRNA Landscape in the Cortico-Accumbal Pathway. Biomedicines. vol 11. issue 5. 2023-05-27. PMID:37239038. |
small rna sequencing (srna-seq) was used to profile mirna transcriptomic changes in the cortico-accumbal pathway [infralimbic- and prelimbic-prefrontal cortex (il and pl) and nucleus accumbens (nac)] of rats with extended access to cocaine self-administration followed by an 18-h withdrawal or a 4-week abstinence. |
2023-05-27 |
2023-08-14 |
rat |
| F Javier Rubio, Daniel E Olivares, Christopher Dunn, Shiliang Zhang, Elias M Hilaire, Akeem Henry, Carlos Mejias-Aponte, Carlos J Nogueras-Ortiz, Pooja V Selvam, Fabio C Cruz, Rajtarun Madangopal, Marisela Morales, Bruce T Hop. Flow cytometry of synaptoneurosomes (FCS) reveals increased ribosomal S6 and calcineurin proteins in activated medial prefrontal cortex to nucleus accumbens synapses. The Journal of neuroscience : the official journal of the Society for Neuroscience. 2023-05-09. PMID:37160369. |
after injecting yfp-expressing aav into medial prefrontal cortex (mpfc) to label terminals in nucleus accumbens (nac) of rats, we injected 20 mg/kg of cocaine in a novel context (cocaine+novelty) to activate synapses, and prepared nac synaptoneurosomes 0-60 min following injections. |
2023-05-09 |
2023-08-14 |
rat |
| Yi He, Junshi Wang, King-Lun Li, Yao Q Wang, Zachary Freyberg, Yan Don. Membrane excitability of nucleus accumbens neurons gates the incubation of cocaine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-04-11. PMID:37041207. |
membrane excitability of nucleus accumbens neurons gates the incubation of cocaine craving. |
2023-04-11 |
2023-08-14 |
mouse |
| Yi He, Junshi Wang, King-Lun Li, Yao Q Wang, Zachary Freyberg, Yan Don. Membrane excitability of nucleus accumbens neurons gates the incubation of cocaine craving. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-04-11. PMID:37041207. |
expression of incubated cocaine seeking is mediated, in part, by cocaine-induced cellular adaptations in medium spiny neurons (msns) within the nucleus accumbens (nac). |
2023-04-11 |
2023-08-14 |
mouse |
| Kyle D Ketchesin, Darius D Becker-Krail, Xiangning Xue, Rashaun S Wilson, TuKiet T Lam, Kenneth R Williams, Angus C Nairn, George C Tseng, Ryan W Loga. Differential Effects of Cocaine and Morphine on the Diurnal Regulation of the Mouse Nucleus Accumbens Proteome. bioRxiv : the preprint server for biology. 2023-03-13. PMID:36909659. |
differential effects of cocaine and morphine on the diurnal regulation of the mouse nucleus accumbens proteome. |
2023-03-13 |
2023-08-14 |
mouse |
| Mark D Namba, Megan N Phillips, Peng-Jen Chen, Benjamin E Blass, M Foster Olive, Janet L Neisewande. HIV gp120 impairs nucleus accumbens neuroimmune function and dopamine D3 receptor-mediated inhibition of cocaine seeking in male rats. Addiction neuroscience. vol 5. 2023-03-13. PMID:36909738. |
hiv gp120 impairs nucleus accumbens neuroimmune function and dopamine d3 receptor-mediated inhibition of cocaine seeking in male rats. |
2023-03-13 |
2023-08-14 |
human |
| Mark D Namba, Megan N Phillips, Peng-Jen Chen, Benjamin E Blass, M Foster Olive, Janet L Neisewande. HIV gp120 impairs nucleus accumbens neuroimmune function and dopamine D3 receptor-mediated inhibition of cocaine seeking in male rats. Addiction neuroscience. vol 5. 2023-03-13. PMID:36909738. |
moreover, postmortem analysis of nucleus accumbens (nac) core neuroimmune function indicated cocaine abstinence- and gp120-induced impairments, and the expression of several immune factors within the nac core significantly correlated with cocaine-seeking behavior. |
2023-03-13 |
2023-08-14 |
human |
| Szu-Ying Yeh, Molly Estill, Casey K Lardner, Caleb J Browne, Angelica Minier-Toribio, Rita Futamura, Katherine Beach, Catherine A McManus, Song-Jun Xu, Shuo Zhang, Elizabeth A Heller, Li Shen, Eric J Nestle. Cell Type-Specific Whole-Genome Landscape of ΔFOSB Binding in the Nucleus Accumbens After Chronic Cocaine Exposure. Biological psychiatry. 2023-03-11. PMID:36906500. |
cell type-specific whole-genome landscape of Δfosb binding in the nucleus accumbens after chronic cocaine exposure. |
2023-03-11 |
2023-08-14 |
Not clear |
| Arthur Godino, Marine Salery, Romain Durand-de Cuttoli, Molly S Estill, Leanne M Holt, Rita Futamura, Caleb J Browne, Philipp Mews, Peter J Hamilton, Rachael L Neve, Li Shen, Scott J Russo, Eric J Nestle. Transcriptional control of nucleus accumbens neuronal excitability by retinoid X receptor alpha tunes sensitivity to drug rewards. Neuron. 2023-03-08. PMID:36889314. |
in the nucleus accumbens (nac) of male and female mice, we show that although its own expression remains unaltered after cocaine exposure, rxrα controls plasticity- and addiction-relevant transcriptional programs in both dopamine receptor d1- and d2-expressing medium spiny neurons, which in turn modulate intrinsic excitability and synaptic activity of these nac cell types. |
2023-03-08 |
2023-08-14 |
mouse |
| Soren D Emerson, Maxime Chevée, Philipp Mews, Erin S Calipar. The transcriptional response to acute cocaine is inverted in male mice with a history of cocaine self-administration and withdrawal throughout the mesocorticolimbic system. Molecular and cellular neurosciences. 2023-03-03. PMID:36868542. |
in this study, we utilized rna sequencing to characterize how the transcriptome-wide effects of acute cocaine exposure were altered by a history of cocaine self-administration and long-term withdrawal (30 days) in the ventral tegmental area (vta), nucleus accumbens (nac), and prefrontal cortex (pfc) in male mice. |
2023-03-03 |
2023-08-14 |
mouse |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
high frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. |
2023-02-16 |
2023-08-14 |
rat |
| Jason Yuen, Abhinav Goyal, Aaron E Rusheen, Abbas Z Kouzani, Michael Berk, Jee Hyun Kim, Susannah J Tye, Charles D Blaha, Kevin E Bennet, Kendall H Lee, Hojin Shin, Yoonbae O. High frequency deep brain stimulation can mitigate the acute effects of cocaine administration on tonic dopamine levels in the rat nucleus accumbens. Frontiers in neuroscience. vol 17. 2023-02-16. PMID:36793536. |
cocaine's addictive properties stem from its capacity to increase tonic extracellular dopamine levels in the nucleus accumbens (nac). |
2023-02-16 |
2023-08-14 |
rat |
| Ryan P Bell, Sheri L Towe, Kareem Al-Khalil, Matthew Gibson, Tauseef Nadeem, Christina S Mead. Additive cortical gray matter deficits in people living with HIV who use cocaine. Journal of neurovirology. 2023-02-14. PMID:36787045. |
within subcortical regions, cocaine use was independently associated with higher volume in the dorsal striatum and pallidum, while hiv disease was associated with lower volume in the nucleus accumbens and thalamus. |
2023-02-14 |
2023-08-14 |
human |
| Sarah E Swinford-Jackson, Matthew T Rich, Phillip J Huffman, Melissa C Knouse, Arthur S Thomas, Sharvari Mankame, Samantha J Worobey, R Christopher Pierc. Low frequency optogenetic deep brain stimulation of nucleus accumbens dopamine D1 or D2 receptor-containing neurons attenuates cocaine seeking selectively in male rats in part by reversing synaptic plasticity deficits. bioRxiv : the preprint server for biology. 2023-02-07. PMID:36747662. |
low frequency optogenetic deep brain stimulation of nucleus accumbens dopamine d1 or d2 receptor-containing neurons attenuates cocaine seeking selectively in male rats in part by reversing synaptic plasticity deficits. |
2023-02-07 |
2023-08-14 |
rat |