| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mark D Namba, Qiaowei Xie, Kyewon Park, Joshua G Jackson, Jacqueline M Barke. EcoHIV Infection Modulates the Effects of Cocaine Exposure Pattern and Abstinence on Cocaine Seeking and Neuroimmune Protein Expression in Male Mice. bioRxiv : the preprint server for biology. 2024-04-25. PMID:38659915. |
analysis of corticolimbic cx3cl1-cx3cr1 and glutamate receptor expression revealed alterations in medial prefrontal cortex (mpfc) cx3cl1 and nucleus accumbens (nac) glun2a receptors that correlated with cocaine seeking following daily cocaine exposure. |
2024-04-25 |
2024-04-28 |
mouse |
| Freddyson J Martínez-Rivera, Leanne M Holt, Angélica Minier-Toribio, Molly Estill, Szu-Ying Yeh, Solange Tofani, Rita Futamura, Caleb J Browne, Philipp Mews, Li Shen, Eric J Nestle. Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559084. |
transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens. |
2024-04-01 |
2024-04-04 |
rat |
| Freddyson J Martínez-Rivera, Leanne M Holt, Angélica Minier-Toribio, Molly Estill, Szu-Ying Yeh, Solange Tofani, Rita Futamura, Caleb J Browne, Philipp Mews, Li Shen, Eric J Nestle. Transcriptional characterization of cocaine withdrawal versus extinction within nucleus accumbens. bioRxiv : the preprint server for biology. 2024-04-01. PMID:38559084. |
cocaine use disorder (cud) exemplifies this phenomenon in which neurobiological modifications hijack brain reward regions such as the nucleus accumbens (nac) to manifest craving and withdrawal-like symptoms. |
2024-04-01 |
2024-04-04 |
rat |
| Henrique Nunes Pereira Oliva, Tiago Paiva Prudente, Eric J Nunes, Kelly P Cosgrove, Rajiv Radhakrishnan, Marc N Potenza, Gustavo A Angarit. Substance use and spine density: a systematic review and meta-analysis of preclinical studies. Molecular psychiatry. 2024-04-01. PMID:38561468. |
amphetamine, cocaine, and nicotine increased spine density in the nucleus accumbens. |
2024-04-01 |
2024-04-04 |
human |
| Jian Ye, Shuang-Qi Gao, Zi-Cun Liu, Xi Chen, Jin-Gang He, Zhuang-Li H. The HMGB1-RAGE axis in nucleus accumbens facilitates cocaine-induced conditioned place preference via modulating microglial activation. Brain and behavior. vol 14. issue 3. 2024-03-07. PMID:38450910. |
cocaine exposure also induces a release of high mobility group box-1 (hmgb1) from neurons into the extracellular space in the nucleus accumbens (nac). |
2024-03-07 |
2024-03-09 |
Not clear |
| Melinda Hersey, Maddalena Mereu, Claire S Jones, Mattingly K Bartole, Andy Y Chen, Jianjing Cao, Takato Hiranita, Lauren E Chun, Jessica P Lopez, Jonathan L Katz, Amy Hauck Newman, Gianluigi Tand. Dual DAT and sigma receptor inhibitors attenuate cocaine effects on nucleus accumbens dopamine dynamics in rats. The European journal of neuroscience. 2024-03-06. PMID:38444104. |
dual dat and sigma receptor inhibitors attenuate cocaine effects on nucleus accumbens dopamine dynamics in rats. |
2024-03-06 |
2024-03-08 |
rat |
| Cameron J Davidson, John H Hannigan, Shane A Perrine, Scott E Bowe. Abuse-like toluene exposure during early adolescence alters subsequent ethanol and cocaine behavioral effects and brain monoamines in male mice. Neurotoxicology and teratology. 2024-01-10. PMID:38199311. |
analysis of monoamines and their metabolites using high pressure liquid chromatography (hplc) within the medial prefrontal cortex (mpfc), nucleus accumbens (nac), dorsal striatum (dstr), and ventral tegmental area (vta) revealed subtle effects on monoamine or metabolite levels following cumulative dosing that varied by drug (cocaine and ethanol) and abstinence duration. |
2024-01-10 |
2024-01-13 |
mouse |
| Marine Salery, Arthur Godino, Yu Qing Xu, John F Fullard, Romain Durand-de Cuttoli, Alexa R LaBanca, Leanne M Holt, Scott J Russo, Panos Roussos, Eric J Nestle. Transcriptional correlates of cocaine-associated learning in striatal ARC ensembles. bioRxiv : the preprint server for biology. 2024-01-03. PMID:38168167. |
previous work demonstrates the importance of sparse neuronal populations - called neuronal ensembles - in associative learning and cocaine seeking, but it remains unknown whether the encoding vs. retrieval of cocaine-associated memories involves similar or distinct mechanisms of ensemble activation and reactivation in nucleus accumbens (nac). |
2024-01-03 |
2024-01-06 |
Not clear |
| Carolina Caban Rivera, Rachael Price, Ricardo P Fortuna, Chen Li, Chau Do, Justin Shinkle, Marco G Ghilotti, Xiangdang Shi, Lynn G Kirby, George M Smith, Ellen M Unterwal. The ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. bioRxiv : the preprint server for biology. 2023-12-11. PMID:38076811. |
the ventral hippocampus and nucleus accumbens as neural substrates for cocaine contextual memory reconsolidation. |
2023-12-11 |
2023-12-17 |
mouse |
| Mengfan Xia, Tanner L Anderson, Emily R Prantzalos, Tara R Hawkinson, Harrison A Clarke, Shannon B Keohane, Ramon C Sun, Jill R Turner, Pavel I Ortinsk. Correction: Voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. 2023-12-01. PMID:38040958. |
correction: voltage-gated potassium channels control extended access cocaine seeking: a role for nucleus accumbens astrocytes. |
2023-12-01 |
2023-12-10 |
Not clear |
| Madalyn Hafenbreidel, Surya Pandey, Sherri B Briggs, Meghana Arza, Shalakha Bonthu, Cadence Fisher, Annika Tiller, Alice B Hall, Shayna Reed, Natasha Mayorga, Li Lin, Susan Khan, Michael D Cameron, Gavin Rumbaugh, Courtney A Mille. Basolateral Amygdala Corticotropin Releasing Factor Receptor 2 Interacts with Nonmuscle Myosin II to Destabilize Memory in Males. Neurobiology of learning and memory. 2023-11-23. PMID:37995804. |
the effect is highly selective, as nmii inhibition has no effect in other relevant brain regions (e.g., dorsal hippocampus [dphc], nucleus accumbens [nac]), nor does it interfere with associations for other aversive or appetitive stimuli, including cocaine (coc). |
2023-11-23 |
2023-11-29 |
mouse |
| Ingrid Reverte, Claudia Marchetti, Sara Pezza, Soami F Zenoni, Giorgia Scaringi, Laura Ferrucci, Ginevra D'Ottavio, Annabella Pignataro, Diego Andolina, Marcello Raspa, Ferdinando Scavizzi, Marco Venniro, Leslie A Ramsey, Cornelius Gross, Daniele Caprioli, Davide Ragozzin. Microglia-mediated calcium-permeable AMPAR accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal. Brain, behavior, and immunity. 2023-11-15. PMID:37967660. |
microglia-mediated calcium-permeable ampar accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal. |
2023-11-15 |
2023-11-20 |
Not clear |
| Ingrid Reverte, Claudia Marchetti, Sara Pezza, Soami F Zenoni, Giorgia Scaringi, Laura Ferrucci, Ginevra D'Ottavio, Annabella Pignataro, Diego Andolina, Marcello Raspa, Ferdinando Scavizzi, Marco Venniro, Leslie A Ramsey, Cornelius Gross, Daniele Caprioli, Davide Ragozzin. Microglia-mediated calcium-permeable AMPAR accumulation in the nucleus accumbens drives hyperlocomotion during cocaine withdrawal. Brain, behavior, and immunity. 2023-11-15. PMID:37967660. |
during withdrawal from cocaine, calcium permeable-ampa receptors (cp-ampar) progressively accumulate in nucleus accumbens (nac) synapses, a phenomenon linked to behavioral sensitization and drug-seeking. |
2023-11-15 |
2023-11-20 |
Not clear |
| Laia Alegre-Zurano, Alba Caceres-Rodriguez, Paula Berbegal-Sáez, Olivier Lassalle, Olivier Manzoni, Olga Valverd. Cocaine-induced loss of LTD and social impairments are restored by fatty acid amide hydrolase inhibition. Scientific reports. vol 13. issue 1. 2023-10-25. PMID:37880305. |
a single dose of cocaine abolishes endocannabinoid-mediated long-term depression (ecb-ltd) in the nucleus accumbens (nac) within 24 h of administration. |
2023-10-25 |
2023-11-08 |
mouse |
| Rachal D Penrod, Makoto Taniguchi, Angela M Kearns, Jordan L Hopkins, Carmela M Reiche. Differential roles of oxytocin receptors in the prefrontal cortex and nucleus accumbens on cocaine self-administration and reinstatement of cued cocaine seeking in male rats. The international journal of neuropsychopharmacology. 2023-10-24. PMID:37875346. |
differential roles of oxytocin receptors in the prefrontal cortex and nucleus accumbens on cocaine self-administration and reinstatement of cued cocaine seeking in male rats. |
2023-10-24 |
2023-11-08 |
rat |
| Sarah E Swinford-Jackson, R Christopher Pierc. Deep brain stimulation for psychostimulant use disorders. Journal of neural transmission (Vienna, Austria : 1996). 2023-10-12. PMID:37823965. |
we examine the clinical and preclinical evidence for dbs of the nucleus accumbens as a possible therapeutic option for cocaine and methamphetamine use disorders. |
2023-10-12 |
2023-10-15 |
Not clear |
| Caleb J Browne, Philipp Mews, Xianxiao Zhou, Leanne M Holt, Molly Estill, Rita Futamura, Anne Schaefer, Paul J Kenny, Yasmin L Hurd, Li Shen, Bin Zhang, Eric J Nestle. Shared and divergent transcriptomic regulation in nucleus accumbens D1 and D2 medium spiny neurons by cocaine and morphine. bioRxiv : the preprint server for biology. 2023-10-02. PMID:37781621. |
shared and divergent transcriptomic regulation in nucleus accumbens d1 and d2 medium spiny neurons by cocaine and morphine. |
2023-10-02 |
2023-10-07 |
Not clear |
| Devin Rocks, Ivana Jaric, Fabio Bellia, Heining Cham, John M Greally, Masako Suzuki, Marija Kundakovi. Early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine. Cell reports. vol 42. issue 10. 2023-10-01. PMID:37777968. |
early-life stress and ovarian hormones alter transcriptional regulation in the nucleus accumbens resulting in sex-specific responses to cocaine. |
2023-10-01 |
2023-10-07 |
Not clear |
| Sarah M Barry, Gabriella M Barry, Dalia Martinez, Rachel D Penrod, Christopher W Cowa. The activity-regulated cytoskeleton-associated protein, Arc, functions in the nucleus accumbens shell to limit multiple triggers of cocaine-seeking behaviour. Addiction biology. vol 28. issue 10. 2023-09-27. PMID:37753560. |
the activity-regulated cytoskeleton-associated protein (arc) is induced by cocaine in the nucleus accumbens (nac), an important brain reward region, but arc's nac function in sud-related behaviour remains unclear. |
2023-09-27 |
2023-10-07 |
rat |
| Ashley K Crawley, Anirudh Sharma, Kevin R Coffey, Mark O West, David J Barke. Nucleus accumbens shell neurons' early sensitivity to cocaine is associated with future increases in drug intake. Addiction neuroscience. vol 8. 2023-09-04. PMID:37664219. |
we observed that the firing patterns of nucleus accumbens (nac) core and shell neurons exhibited increasing sensitivity to cocaine over the first 6 s-a sessions and maintained a strong negative correlation between drug intake and neuronal firing rates across chronic s-a. |
2023-09-04 |
2023-09-07 |
human |