| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ken T Wakabayashi, Eugene A Kiyatki. Critical role of peripheral drug actions in experience-dependent changes in nucleus accumbens glutamate release induced by intravenous cocaine. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24111505. |
critical role of peripheral drug actions in experience-dependent changes in nucleus accumbens glutamate release induced by intravenous cocaine. |
2014-04-29 |
2023-08-12 |
rat |
| Ken T Wakabayashi, Eugene A Kiyatki. Critical role of peripheral drug actions in experience-dependent changes in nucleus accumbens glutamate release induced by intravenous cocaine. Journal of neurochemistry. vol 128. issue 5. 2014-04-29. PMID:24111505. |
using high-speed amperometry with enzyme-based biosensors in freely moving rats, we show that initial intravenous cocaine induces rapid, transient glutamate (glu) release in the nac (nucleus accumbens), rapidly becoming a stronger, two-component increase with subsequent injections. |
2014-04-29 |
2023-08-12 |
rat |
| Hai-Feng Lu, Peng-Fei Wu, Yuan-Jian Yang, Wen Xiao, Jun Fan, Jing Liu, Yuan-Long Li, Yi Luo, Zhuang-Li Hu, You Jin, Fang Wang, Jian-Guo Che. Interactions between N-ethylmaleimide-sensitive factor and GluR2 in the nucleus accumbens contribute to the expression of locomotor sensitization to cocaine. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 10. 2014-04-29. PMID:24599450. |
interactions between n-ethylmaleimide-sensitive factor and glur2 in the nucleus accumbens contribute to the expression of locomotor sensitization to cocaine. |
2014-04-29 |
2023-08-12 |
rat |
| R M Villalba, Y Smit. Differential striatal spine pathology in Parkinson's disease and cocaine addiction: a key role of dopamine? Neuroscience. vol 251. 2014-04-23. PMID:23867772. |
in pd, nigrostriatal dopamine degeneration results in a significant loss of dendritic spines in the dorsal striatum, while rodents chronically exposed to cocaine and other psychostimulants, display an increase in the density of "thin and immature" spines in the nucleus accumbens (nac). |
2014-04-23 |
2023-08-12 |
Not clear |
| Stephanie K Nygard, Anthony Klambatsen, Ruhal Hazim, Mohamed H Eltareb, Jeff C Blank, Anna J Chang, Vanya Quinones-Jenab, Shirzad Jena. Sexually dimorphic intracellular responses after cocaine-induced conditioned place preference expression. Brain research. vol 1520. 2014-04-11. PMID:23665060. |
in the nucleus accumbens (nac) following cpp expression, cocaine treated animals showed increased phosphorylated erk (perk), phosphorylated creb (pcreb) and Δfosb protein levels. |
2014-04-11 |
2023-08-12 |
rat |
| Andrew F Scheyer, Marina E Wolf, Kuei Y Tsen. A protein synthesis-dependent mechanism sustains calcium-permeable AMPA receptor transmission in nucleus accumbens synapses during withdrawal from cocaine self-administration. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 8. 2014-04-10. PMID:24553949. |
a protein synthesis-dependent mechanism sustains calcium-permeable ampa receptor transmission in nucleus accumbens synapses during withdrawal from cocaine self-administration. |
2014-04-10 |
2023-08-12 |
rat |
| Anthony Purgianto, Andrew F Scheyer, Jessica A Loweth, Kerstin A Ford, Kuei Y Tseng, Marina E Wol. Different adaptations in AMPA receptor transmission in the nucleus accumbens after short vs long access cocaine self-administration regimens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 9. 2014-04-04. PMID:23546386. |
different adaptations in ampa receptor transmission in the nucleus accumbens after short vs long access cocaine self-administration regimens. |
2014-04-04 |
2023-08-12 |
rat |
| Anthony Purgianto, Andrew F Scheyer, Jessica A Loweth, Kerstin A Ford, Kuei Y Tseng, Marina E Wol. Different adaptations in AMPA receptor transmission in the nucleus accumbens after short vs long access cocaine self-administration regimens. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 9. 2014-04-04. PMID:23546386. |
ca(2+)-permeable ampa receptors (cp-ampars) accumulate in the nucleus accumbens (nac) after ∼1 month of withdrawal from a long-access cocaine self-administration regimen (6 h/d, 10d). |
2014-04-04 |
2023-08-12 |
rat |
| Kimberly N Scobie, Diane Damez-Werno, HaoSheng Sun, NingYi Shao, Amy Gancarz, Clarisse H Panganiban, Caroline Dias, JaWook Koo, Paola Caiafa, Lewis Kaufman, Rachael L Neve, David M Dietz, Li Shen, Eric J Nestle. Essential role of poly(ADP-ribosyl)ation in cocaine action. Proceedings of the National Academy of Sciences of the United States of America. vol 111. issue 5. 2014-04-03. PMID:24449909. |
repeated cocaine administration, including self-administration, increased global levels of parp-1 and its mark par in mouse nucleus accumbens (nac), a key brain reward region. |
2014-04-03 |
2023-08-12 |
mouse |
| Kaili Anier, Alexander Zharkovsky, Anti Kald. S-adenosylmethionine modifies cocaine-induced DNA methylation and increases locomotor sensitization in mice. The international journal of neuropsychopharmacology. vol 16. issue 9. 2014-04-01. PMID:23684129. |
using mouse nucleus accumbens (nac) tissue, whole-genome gene expression profiling revealed that repeated sam treatment affected a limited number of genes, but significantly modified cocaine-induced gene expression by blunting non-specifically the cocaine response. |
2014-04-01 |
2023-08-12 |
mouse |
| Briac Halbout, Rick E Bernardi, Anita C Hansson, Rainer Spanage. Incubation of cocaine seeking following brief cocaine experience in mice is enhanced by mGluR1 blockade. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 5. 2014-04-01. PMID:24478360. |
the incubation of cocaine craving describes the time-dependent augmentation of cue-induced cocaine seeking during withdrawal from prolonged cocaine self-administration and requires time-dependent changes in neuroplasticity at the level of glutamatergic synapses in the nucleus accumbens (nac). |
2014-04-01 |
2023-08-12 |
mouse |
| Benjamin D Hobson, Casey E O'Neill, Sophia C Levis, Lisa M Monteggia, Rachael L Neve, David W Self, Ryan K Bachtel. Adenosine A1 and dopamine d1 receptor regulation of AMPA receptor phosphorylation and cocaine-seeking behavior. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 38. issue 10. 2014-03-24. PMID:23598433. |
ampar (α-amino-3-hydroxy-5-methylisoxazole-4-propionate glutamate receptor) stimulation in the nucleus accumbens (nac) is critical in cocaine seeking. |
2014-03-24 |
2023-08-12 |
Not clear |
| Edward P Maguire, Tom Macpherson, Jerome D Swinny, Claire I Dixon, Murray B Herd, Delia Belelli, David N Stephens, Sarah L King, Jeremy J Lamber. Tonic inhibition of accumbal spiny neurons by extrasynaptic α4βδ GABAA receptors modulates the actions of psychostimulants. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 3. 2014-03-13. PMID:24431441. |
within the nucleus accumbens (nac), synaptic gabaa receptors (gabaars) mediate phasic inhibition of medium spiny neurons (msns) and influence behavioral responses to cocaine. |
2014-03-13 |
2023-08-12 |
mouse |
| Jessica A Loweth, Kuei Y Tseng, Marina E Wol. Using metabotropic glutamate receptors to modulate cocaine's synaptic and behavioral effects: mGluR1 finds a niche. Current opinion in neurobiology. vol 23. issue 4. 2014-02-27. PMID:23385114. |
the same relationship has now been demonstrated in the nucleus accumbens (nac), a region that is critical for cocaine craving. |
2014-02-27 |
2023-08-12 |
Not clear |
| Rachel J Smith, Mary Kay Lobo, Sade Spencer, Peter W Kaliva. Cocaine-induced adaptations in D1 and D2 accumbens projection neurons (a dichotomy not necessarily synonymous with direct and indirect pathways). Current opinion in neurobiology. vol 23. issue 4. 2014-02-27. PMID:23428656. |
cocaine exposure causes enduring neuroadaptations in ventral striatum, or nucleus accumbens (nac), an area critically involved in reward learning and relapse of drug seeking. |
2014-02-27 |
2023-08-12 |
Not clear |
| A A Pavlovsky, D Boehning, D Li, Y Zhang, X Fan, T A Gree. Psychological stress, cocaine and natural reward each induce endoplasmic reticulum stress genes in rat brain. Neuroscience. vol 246. 2014-02-24. PMID:23644055. |
rats were subjected to acute or repeated restraint stress or cocaine treatment and mrna was isolated from dorsal striatum, medial prefrontal cortex and nucleus accumbens brain tissue. |
2014-02-24 |
2023-08-12 |
rat |
| R A Chambers, J N McClintick, A M Sentir, S A Berg, M Runyan, K H Choi, H J Edenber. Cortical-striatal gene expression in neonatal hippocampal lesion (NVHL)-amplified cocaine sensitization. Genes, brain, and behavior. vol 12. issue 5. 2014-01-27. PMID:23682998. |
rat genome-wide microarrays containing >24 000 probesets were used to examine separate and co-occurring effects of nvhls and cocaine sensitization (15 mg/kg/day × 5 days) on gene expression within medial prefrontal cortex (mpfc), nucleus accumbens (nac), and caudate-putamen (capu). |
2014-01-27 |
2023-08-12 |
rat |
| Mary Kay Lobo, Samir Zaman, Diane M Damez-Werno, Ja Wook Koo, Rosemary C Bagot, Jennifer A DiNieri, Alexandria Nugent, Eric Finkel, Dipesh Chaudhury, Ramesh Chandra, Efrain Riberio, Jacqui Rabkin, Ezekiell Mouzon, Roger Cachope, Joseph F Cheer, Ming-Hu Han, David M Dietz, David W Self, Yasmin L Hurd, Vincent Vialou, Eric J Nestle. ΔFosB induction in striatal medium spiny neuron subtypes in response to chronic pharmacological, emotional, and optogenetic stimuli. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 33. issue 47. 2014-01-21. PMID:24259563. |
we make use of fluorescent reporter bac transgenic mice to evaluate induction of Δfosb in dopamine receptor 1 (d1) enriched and dopamine receptor 2 (d2) enriched msns in ventral striatum, nucleus accumbens (nac) shell and core, and in dorsal striatum (dstr) after chronic exposure to several drugs of abuse including cocaine, ethanol, Δ(9)-tetrahydrocannabinol, and opiates; the antipsychotic drug, haloperidol; juvenile enrichment; sucrose drinking; calorie restriction; the serotonin selective reuptake inhibitor antidepressant, fluoxetine; and social defeat stress. |
2014-01-21 |
2023-08-12 |
mouse |
| Edgardo Falcon, Angela Ozburn, Shibani Mukherjee, Kole Roybal, Colleen A McClun. Differential regulation of the period genes in striatal regions following cocaine exposure. PloS one. vol 8. issue 6. 2014-01-16. PMID:23776671. |
thus, we wanted to determine the effects of chronic cocaine on the expression of several circadian genes in the nucleus accumbens (nac) and caudate putamen (cp), regions of the brain known to be involved in the behavioral responses to drugs of abuse. |
2014-01-16 |
2023-08-12 |
mouse |
| Su Yeon Seo, Jeong Hwan Oh, Eun Sang Cho. Protein kinase G increases AMPA receptor GluR1 phosphorylation at serine 845 after repeated cocaine administration in the rat nucleus accumbens. Neuroscience letters. vol 544. 2014-01-06. PMID:23583340. |
protein kinase g increases ampa receptor glur1 phosphorylation at serine 845 after repeated cocaine administration in the rat nucleus accumbens. |
2014-01-06 |
2023-08-12 |
rat |