All Relations between cocaine and nucleus accumbens

Publication Sentence Publish Date Extraction Date Species
Eduardo Alvear, Dietrich von Baer, Claudia Mardones, Antonieta Hitschfel. Determination of cocaine and its major metabolite benzoylecgonine in several matrices obtained from deceased individuals with presumed drug consumption prior to death. Journal of forensic and legal medicine. vol 23. 2014-12-29. PMID:24661704. to address this issue, we implemented and compared in our study the systematic evaluation of extraction, chromatographic separation, and quantification of cocaine and benzoylecgonine in different biological matrices (right and left cardiac blood, femoral arterial and venous blood, urine, vitreous humor, cerebrospinal fluid, brain accumbens nucleus, brain ventral tegmental area, and liver). 2014-12-29 2023-08-12 Not clear
Jeremy M Reimers, Jessica A Loweth, Marina E Wol. BDNF contributes to both rapid and homeostatic alterations in AMPA receptor surface expression in nucleus accumbens medium spiny neurons. The European journal of neuroscience. vol 39. issue 7. 2014-12-18. PMID:24712995. we recently showed that intracranial injection of bdnf into the rat nucleus accumbens (nac), a key region for cocaine addiction, rapidly increases α-amino-3-hyroxy-5-methyl-4-isoxazole-propionic acid receptor (ampar) surface expression. 2014-12-18 2023-08-13 mouse
Beata Bystrowska, Irena Smaga, Małgorzata Frankowska, Małgorzata Fili. Changes in endocannabinoid and N-acylethanolamine levels in rat brain structures following cocaine self-administration and extinction training. Progress in neuro-psychopharmacology & biological psychiatry. vol 50. 2014-12-11. PMID:24334211. in addition, we detected increases (>150%) in the levels of oea and pea in the limbic areas in both cocaine treated groups, as well as an increase in the tissue levels of oea in the dorsal striatum in only the yoked cocaine group and increases in the tissue levels of pea in the dorsal striatum (both cocaine groups) and the nucleus accumbens (yoked cocaine group only). 2014-12-11 2023-08-12 rat
Andrew F MacAskill, John M Cassel, Adam G Carte. Cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens. Nature neuroscience. vol 17. issue 9. 2014-12-01. PMID:25108911. cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens. 2014-12-01 2023-08-13 mouse
Andrew F MacAskill, John M Cassel, Adam G Carte. Cocaine exposure reorganizes cell type- and input-specific connectivity in the nucleus accumbens. Nature neuroscience. vol 17. issue 9. 2014-12-01. PMID:25108911. repeated exposure to cocaine alters the structural and functional properties of medium spiny neurons (msns) in the nucleus accumbens (nac). 2014-12-01 2023-08-13 mouse
Michael P Saddoris, Regina M Carell. Cocaine self-administration abolishes associative neural encoding in the nucleus accumbens necessary for higher-order learning. Biological psychiatry. vol 75. issue 2. 2014-11-18. PMID:24035479. cocaine self-administration abolishes associative neural encoding in the nucleus accumbens necessary for higher-order learning. 2014-11-18 2023-08-12 human
Jeffrey L Barr, Gina L Forster, Ellen M Unterwal. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of neurochemistry. vol 130. issue 4. 2014-09-29. PMID:24832868. repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal nmda receptor subunit expression. 2014-09-29 2023-08-13 rat
Jeffrey L Barr, Gina L Forster, Ellen M Unterwal. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of neurochemistry. vol 130. issue 4. 2014-09-29. PMID:24832868. in this study, in vivo microdialysis in freely moving adult male sprague-dawley rats was used to investigate the effect of repeated cocaine on ventral hippocampus-mediated dopaminergic transmission within the medial shell of the nucleus accumbens. 2014-09-29 2023-08-13 rat
Jeffrey L Barr, Gina L Forster, Ellen M Unterwal. Repeated cocaine enhances ventral hippocampal-stimulated dopamine efflux in the nucleus accumbens and alters ventral hippocampal NMDA receptor subunit expression. Journal of neurochemistry. vol 130. issue 4. 2014-09-29. PMID:24832868. a behaviorally sensitizing regimen of cocaine (20 mg/kg, ip 7 days) also sensitized ventral hippocampus (hipp)-mediated dopaminergic transmission within the nucleus accumbens (nac) to nmda stimulation (bolts). 2014-09-29 2023-08-13 rat
Yafang Zhang, Elizabeth J Crofton, Dingge Li, Mary Kay Lobo, Xiuzhen Fan, Eric J Nestler, Thomas A Gree. Overexpression of DeltaFosB in nucleus accumbens mimics the protective addiction phenotype, but not the protective depression phenotype of environmental enrichment. Frontiers in behavioral neuroscience. vol 8. 2014-09-15. PMID:25221490. chronic stress or chronic cocaine treatment each elevates Δfosb protein levels in the nucleus accumbens (nac) of ic rats, but not of ec rats due to an already elevated basal accumulation of Δfosb seen under ec conditions. 2014-09-15 2023-08-13 rat
Lisa A Briand, Blake A Kimmey, Pavel I Ortinski, Richard L Huganir, R Christopher Pierc. Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24126453. disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse. 2014-09-10 2023-08-12 Not clear
Lisa A Briand, Blake A Kimmey, Pavel I Ortinski, Richard L Huganir, R Christopher Pierc. Disruption of glutamate receptor-interacting protein in nucleus accumbens enhances vulnerability to cocaine relapse. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 39. issue 3. 2014-09-10. PMID:24126453. the current study demonstrates that conditional deletion of grip within the nucleus accumbens potentiates cue-induced reinstatement of cocaine seeking without affecting operant learning, locomotor activity, or reinstatement of natural reward seeking. 2014-09-10 2023-08-12 Not clear
Jennifer A Cummings, Lakshmikripa Jagannathan, Lisa R Jackson, Jill B Becke. Sex differences in the effects of estradiol in the nucleus accumbens and striatum on the response to cocaine: neurochemistry and behavior. Drug and alcohol dependence. vol 135. 2014-09-08. PMID:24332790. sex differences in the effects of estradiol in the nucleus accumbens and striatum on the response to cocaine: neurochemistry and behavior. 2014-09-08 2023-08-12 Not clear
Amy M Gancarz-Kausch, Gabrielle L Schroeder, Clarisse Panganiban, Danielle Adank, Monica S Humby, Michael A Kausch, Stewart D Clark, David M Diet. Transforming growth factor beta receptor 1 is increased following abstinence from cocaine self-administration, but not cocaine sensitization. PloS one. vol 8. issue 12. 2014-08-31. PMID:24386286. here, we investigated transforming growth factor-beta type i receptor (tgf-β r1) expression in the nucleus accumbens (nac) following periods of withdrawal from cocaine self-administration (sa) and a sensitizing regimen of non-contingent cocaine. 2014-08-31 2023-08-12 rat
Lucia Caffino, Chiara Cassina, Giuseppe Giannotti, Alessandro Orrù, Federico Moro, Angelo Di Clemente, Giorgio Racagni, Fabio Fumagalli, Luigi Cerv. Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. The international journal of neuropsychopharmacology. vol 17. issue 2. 2014-08-26. PMID:23953174. short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αcamkii autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. 2014-08-26 2023-08-12 rat
Lucia Caffino, Chiara Cassina, Giuseppe Giannotti, Alessandro Orrù, Federico Moro, Angelo Di Clemente, Giorgio Racagni, Fabio Fumagalli, Luigi Cerv. Short-term abstinence from cocaine self-administration, but not passive cocaine infusion, elevates αCaMKII autophosphorylation in the rat nucleus accumbens and medial prefrontal cortex. The international journal of neuropsychopharmacology. vol 17. issue 2. 2014-08-26. PMID:23953174. increased αcamkii autophosphorylation in the nucleus accumbens (nac) and medial prefrontal cortex (mpfc), but not dorsolateral striatum (dls), was found 24 h, but not immediately, after the last cocaine self-administration session. 2014-08-26 2023-08-12 rat
Balakrishnan Selvakumar, Peter W Campbell, Mike Milovanovic, Diana J Park, Anthony R West, Solomon H Snyder, Marina E Wol. AMPA receptor upregulation in the nucleus accumbens shell of cocaine-sensitized rats depends upon S-nitrosylation of stargazin. Neuropharmacology. vol 77. 2014-08-26. PMID:24035918. behavioral sensitization to cocaine is associated with increased ampa receptor (ampar) surface expression in the nucleus accumbens (nac). 2014-08-26 2023-08-12 rat
Wei-Lun Sun, Nortorious T Coleman, Agnieszka Zelek-Molik, Sarah M Barry, Timothy W Whitfield, Jacqueline F McGint. Relapse to cocaine-seeking after abstinence is regulated by cAMP-dependent protein kinase A in the prefrontal cortex. Addiction biology. vol 19. issue 1. 2014-08-18. PMID:23461423. abstinence from cocaine self-administration (sa) is associated with neuroadaptations in the prefrontal cortex (pfc) and nucleus accumbens (nac) that are implicated in cocaine-induced neuronal plasticity and relapse to drug-seeking. 2014-08-18 2023-08-12 Not clear
Ainhoa Plaza-Zabala, Xuan Li, Mike Milovanovic, Jessica A Loweth, Rafael Maldonado, Fernando Berrendero, Marina E Wol. An investigation of interactions between hypocretin/orexin signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions and after cocaine exposure. Neuroscience letters. vol 557 Pt B. 2014-08-18. PMID:24262606. an investigation of interactions between hypocretin/orexin signaling and glutamate receptor surface expression in the rat nucleus accumbens under basal conditions and after cocaine exposure. 2014-08-18 2023-08-12 rat
Sade Spencer, Robyn M Brown, Gabriel C Quintero, Yonatan M Kupchik, Charles A Thomas, Kathryn J Reissner, Peter W Kaliva. α2δ-1 signaling in nucleus accumbens is necessary for cocaine-induced relapse. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 34. issue 25. 2014-08-12. PMID:24948814. relapse to cocaine seeking is associated with potentiated excitatory synapses in nucleus accumbens. 2014-08-12 2023-08-13 rat