| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G V Johnson, R S Jop. Aluminum impairs glucose utilization and cholinergic activity in rat brain in vitro. Toxicology. vol 40. issue 1. 1986-07-24. PMID:3012824. |
aluminum chloride also inhibited high affinity choline transport in synaptosomes prepared from rat cortex and from hippocampus with an ic50 of approximately 0.5 mm. |
1986-07-24 |
2023-08-11 |
rat |
| H Lai, J Zabawska, A Horit. Sodium-dependent, high-affinity choline uptake in hippocampus and frontal cortex of the rat affected by acute restraint stress. Brain research. vol 372. issue 2. 1986-07-07. PMID:3708367. |
sodium-dependent, high-affinity choline uptake in hippocampus and frontal cortex of the rat affected by acute restraint stress. |
1986-07-07 |
2023-08-11 |
rat |
| H Lai, J Zabawska, A Horit. Sodium-dependent, high-affinity choline uptake in hippocampus and frontal cortex of the rat affected by acute restraint stress. Brain research. vol 372. issue 2. 1986-07-07. PMID:3708367. |
acute (45-min) restraint stress decreased sodium-dependent, high-affinity choline uptake in the hippocampus and frontal cortex of rats. |
1986-07-07 |
2023-08-11 |
rat |
| J A Richter, J M Gormle. Inhibition of high-affinity choline uptake in the rat hippocampus by in vivo injection of phenobarbital in the medial septum. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:3009793. |
inhibition of high-affinity choline uptake in the rat hippocampus by in vivo injection of phenobarbital in the medial septum. |
1986-06-23 |
2023-08-11 |
rat |
| J A Richter, J M Gormle. Inhibition of high-affinity choline uptake in the rat hippocampus by in vivo injection of phenobarbital in the medial septum. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:3009793. |
inhibit the activity in the septal-hippocampal cholinergic pathway as assessed by an inhibition of choline uptake into hippocampal synaptosomes in vitro. |
1986-06-23 |
2023-08-11 |
rat |
| J A Richter, J M Gormle. Inhibition of high-affinity choline uptake in the rat hippocampus by in vivo injection of phenobarbital in the medial septum. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:3009793. |
it was found that phenobarbital, barbital and muscimol injected into the medial septal area inhibited choline uptake in the hippocampus. |
1986-06-23 |
2023-08-11 |
rat |
| J A Richter, J M Gormle. Inhibition of high-affinity choline uptake in the rat hippocampus by in vivo injection of phenobarbital in the medial septum. The Journal of pharmacology and experimental therapeutics. vol 237. issue 2. 1986-06-23. PMID:3009793. |
in contrast, the stimulation of choline uptake in the hippocampus by picrotoxin occurred when it was injected in the lateral septum but not in the medial septum. |
1986-06-23 |
2023-08-11 |
rat |
| D Beracochea, T P Durkin, R Jaffar. On the involvement of the central cholinergic system in memory deficits induced by long term ethanol consumption in mice. Pharmacology, biochemistry, and behavior. vol 24. issue 3. 1986-06-17. PMID:3703888. |
parallel neurochemical analysis showed that chronic ethanol treatment induced a slight (12%) but significant decrease in hippocampal sodium-dependent high affinity choline uptake. |
1986-06-17 |
2023-08-11 |
mouse |
| M Nakahiro, H Yoshid. The "antidementia drug" pantoyl-gamma-aminobutyric acid increases high affinity uptake of choline by slices of rat brain. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3703173. |
depolarization caused by increasing the k+ concentration to 25 mm for 30 min before incubation with [3h]choline enhanced the uptake of radioactivity by slices of cerebral cortex, hippocampus and striatum during a 5 min incubation in the presence of 1 microm [3h]choline. |
1986-06-06 |
2023-08-11 |
rat |
| M Nakahiro, H Yoshid. The "antidementia drug" pantoyl-gamma-aminobutyric acid increases high affinity uptake of choline by slices of rat brain. Neuropharmacology. vol 25. issue 3. 1986-06-06. PMID:3703173. |
since the high affinity uptake of choline is considered to be a regulatory step in the synthesis of acetylcholine (ach), these results suggest that pantoyl-gaba increases the synthesis of ach in cholinergic terminals in the cerebral cortex and hippocampus. |
1986-06-06 |
2023-08-11 |
rat |
| T Mennini, M Gobbi, F Ponzio, S Garattin. Neurochemical effects of buspirone in rat hippocampus: evidence for selective activation of 5HT neurons. Archives internationales de pharmacodynamie et de therapie. vol 279. issue 1. 1986-05-22. PMID:2421657. |
oral administration of buspirone does not modify the hippocampal concentrations of gaba, acetylcholine, choline and of 3h-flunitrazepam specifically bound in vivo, but results in a dose-dependent reduction of 5hiaa and noradrenaline concentrations. |
1986-05-22 |
2023-08-11 |
rat |
| F Pedata, L Giovannelli, P De Sarno, G Pepe. Effect of adenosine, adenosine derivatives, and caffeine on acetylcholine release from brain synaptosomes: interaction with muscarinic autoregulatory mechanisms. Journal of neurochemistry. vol 46. issue 5. 1986-05-19. PMID:3958718. |
synaptosomes, prepared from rat cerebral cortex and hippocampus, were preincubated with [methyl-3h]choline. |
1986-05-19 |
2023-08-11 |
rat |
| F Pedata, L Giovannelli, P De Sarno, G Pepe. Effect of adenosine, adenosine derivatives, and caffeine on acetylcholine release from brain synaptosomes: interaction with muscarinic autoregulatory mechanisms. Journal of neurochemistry. vol 46. issue 5. 1986-05-19. PMID:3958718. |
high-voltage electrophoretic separation showed that in the presence of physostigmine, the k+-evoked 3h efflux from hippocampal synaptosomes was 90% [3h]acetylcholine and 10% [3h]choline. |
1986-05-19 |
2023-08-11 |
rat |
| D Budai, J Rícný, P Kása, S Tuce. 4-(1-Naphthylvinyl)pyridine decreases brain acetylcholine in vivo, but does not alter the level of acetyl-CoA. Journal of neurochemistry. vol 46. issue 3. 1986-04-02. PMID:3950616. |
the effects of intraperitoneally administered 4-(1-naphthylvinyl)pyridine (nvp; 200 mg/kg) on the concentrations of acetylcholine (ach), choline (ch), and acetyl-coa (accoa) in rat striatum, cortex, hippocampus, and cerebellum were investigated. |
1986-04-02 |
2023-08-11 |
rat |
| C Rauca, E Kammerer, H Matthie. The influence of enhanced K+-concentration on the uptake and acetylation of choline in hippocampus slices of rats. Biomedica biochimica acta. vol 44. issue 11-12. 1986-03-14. PMID:4091835. |
the influence of enhanced k+-concentration on the uptake and acetylation of choline in hippocampus slices of rats. |
1986-03-14 |
2023-08-11 |
rat |
| C Rauca, E Kammerer, H Matthie. The influence of enhanced K+-concentration on the uptake and acetylation of choline in hippocampus slices of rats. Biomedica biochimica acta. vol 44. issue 11-12. 1986-03-14. PMID:4091835. |
the effect of k+-evoked acetylcholine (ach) release on uptake and acetylation of choline (ch) in hippocampus slices of rats was studied by use of two different temporal schedules of incubation with labeled precursor and k+-stimulation of tissue. |
1986-03-14 |
2023-08-11 |
rat |
| M Liscovitch, A Freese, J K Blusztajn, R J Wurtma. High-performance liquid chromatography of water-soluble choline metabolites. Analytical biochemistry. vol 151. issue 1. 1986-03-07. PMID:4091278. |
this procedure has been applied in tracer studies of choline metabolism utilizing the neuronal ng108-15 cell line and rat hippocampal slices as model systems. |
1986-03-07 |
2023-08-11 |
rat |
| M Liscovitch, A Freese, J K Blusztajn, R J Wurtma. High-performance liquid chromatography of water-soluble choline metabolites. Analytical biochemistry. vol 151. issue 1. 1986-03-07. PMID:4091278. |
while the compounds labeled in the ng108-15 cells were primarily phosphorylcholine and glycerophosphocholine, reflecting high rates of phospholipid turnover, in the hippocampal slices choline and acetylcholine were the major labeled species. |
1986-03-07 |
2023-08-11 |
rat |
| T W Vickroy, M Watson, S M Leventer, W R Roeske, I Hanin, H I Yamamur. Regional differences in ethylcholine mustard aziridinium ion (AF64A)-induced deficits in presynaptic cholinergic markers for the rat central nervous system. The Journal of pharmacology and experimental therapeutics. vol 235. issue 3. 1986-02-12. PMID:3841155. |
a similar reduction was noted in high-affinity binding of [3h]hemicholinium-3 (a putative radioligand for sodium-dependent high-affinity choline uptake sites on cholinergic nerve terminals) in hippocampal membranes (59-65%). |
1986-02-12 |
2023-08-11 |
rat |
| D N Middlemis. The calcium channel activator, Bay K 8644, enhances K+-evoked efflux of acetylcholine and noradrenaline from rat brain slices. Naunyn-Schmiedeberg's archives of pharmacology. vol 331. issue 1. 1986-01-22. PMID:2415829. |
slices of rat brain were incubated with either (3h) choline (hippocampus) or (3h) noradrenaline (hypothalamus) and superfused with krebs buffer. |
1986-01-22 |
2023-08-11 |
rat |