| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Chuck T Chen, David W L Ma, John H Kim, Howard T J Mount, Richard P Bazine. The low density lipoprotein receptor is not necessary for maintaining mouse brain polyunsaturated fatty acid concentrations. Journal of lipid research. vol 49. issue 1. 2008-03-07. PMID:17932396. |
there were no differences in phosphatidylserine, phosphatidylinositol, ethanolamine, or choline glycerophospholipid esterified pufa or saturated or monounsaturated fatty acid concentrations in the cortex or brain stem between ldlr(-/-) and wild-type mice. |
2008-03-07 |
2023-08-12 |
mouse |
| Alexander Unrath, Albert C Ludolph, Jan Kassube. Brain metabolites in definite amyotrophic lateral sclerosis. A longitudinal proton magnetic resonance spectroscopy study. Journal of neurology. vol 254. issue 8. 2008-02-01. PMID:17431700. |
here, single-voxel proton magnetic resonance spectroscopy ((1)h mrs) of the gray matter of the motor cortex and the white matter including the pyramidal tracts was used to investigate concentrations of n-acetylaspartate (naa), creatine (cr), choline (cho), myoinositol, glutamate, and glutamine in patients with definite als in a longitudinal design (three measurements at study inclusion, after 3 and 6 months). |
2008-02-01 |
2023-08-12 |
Not clear |
| R E OLSON, H W DEAN. A physiological and cytochemical study of the kidney and the adrenal cortex during acute choline deficiency in weanling rats. The Journal of nutrition. vol 39. issue 1. 2007-12-27. PMID:18143001. |
a physiological and cytochemical study of the kidney and the adrenal cortex during acute choline deficiency in weanling rats. |
2007-12-27 |
2023-08-12 |
rat |
| María Gabriela Cheluja, Mariano José Scolari, Trinidad María Coelho, Mariano Guillermo Blake, Mariano Martín Boccia, Carlos María Baratti, Gabriela Beatriz Acost. L-serine and GABA uptake by synaptosomes during postnatal development of rat. Comparative biochemistry and physiology. Part A, Molecular & integrative physiology. vol 146. issue 4. 2007-06-28. PMID:16481208. |
the uptake of [3h]l-serine was temperature dependent in synaptosomal fractions prepared from cerebral cortex of rats in postnatal days 5, 7, 13 and 21, but stronger dependence was observed in adult brain, irrespective of the presence of na+, k+ or choline ions. |
2007-06-28 |
2023-08-12 |
rat |
| Tiffany J Mellott, Maximillian T Follettie, Veronica Diesl, Andrew A Hill, Ignacio Lopez-Coviella, Jan Krzysztof Blusztaj. Prenatal choline availability modulates hippocampal and cerebral cortical gene expression. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 21. issue 7. 2007-05-30. PMID:17264169. |
we analyzed mrna expression in brains of prenatally choline-deficient, choline-supplemented, or control rats of various ages [postnatal days (p) 1 to 34 for hippocampus and e16 to p34 for cortex] using oligonucleotide microarrays and found alterations in gene expression levels evoked by prenatal choline intake that were, in most cases, transient occurring during the p15-p34 period. |
2007-05-30 |
2023-08-12 |
rat |
| G Mavroudis, M J W Prior, T Lister, C C Nolan, D E Ra. Neurochemical and oedematous changes in 1,3-dinitrobenzene-induced astroglial injury in rat brain from a 1H-nuclear magnetic resonance perspective. Journal of neural transmission (Vienna, Austria : 1996). vol 113. issue 9. 2007-05-02. PMID:16362630. |
(1)h-nuclear magnetic resonance spectroscopic analysis before the onset of astrocytic damage, showed a global elevation of lactate, whereas choline containing compounds increased in the non-vulnerable cerebral cortex, yet decreased in the vulnerable brainstem. |
2007-05-02 |
2023-08-12 |
rat |
| Paul R Lockman, Julie Gaasch, Ghia McAfee, Thomas J Abbruscato, Cornelis J Van der Schyf, David D Alle. Nicotine exposure does not alter plasma to brain choline transfer. Neurochemical research. vol 31. issue 4. 2007-03-22. PMID:16758358. |
no significant changes in choline uptake after acute or chronic nicotine exposure were observed in whole brain or cortex. |
2007-03-22 |
2023-08-12 |
rat |
| Oscar U Scremin, Mingen Grace Li, Margareth Roch, Ruth Booth, Donald J Jende. Acetylcholine and choline dynamics provide early and late markers of traumatic brain injury. Brain research. vol 1124. issue 1. 2007-01-23. PMID:17084821. |
we assessed acetylcholine (ach) and choline (ch) dynamics 2.5 h, 1, 4 and 14 days after cerebral cortex impact injury or craniotomy only in adult male sprague-dawley rats. |
2007-01-23 |
2023-08-12 |
rat |
| Amanda M Ill, Todd R Mitchell, Elizabeth B Neely, James R Conno. Metabolic analysis of mouse brains that have compromised iron storage. Metabolic brain disease. vol 21. issue 2-3. 2007-01-10. PMID:16855871. |
in h-ferritin deficient mice, we found significant increases in striatal glutamate, hippocampal choline, and n-acetyl-aspartyl-glutamate in both the cortex and the hippocampus (t-test, p < 0.05). |
2007-01-10 |
2023-08-12 |
mouse |
| b' Mia Emg\\xc3\\xa5rd, Michela Paradisi, Stefania Pirondi, Mercedes Fernandez, Luciana Giardino, Laura Calz\\xc3\\xa. Prenatal glucocorticoid exposure affects learning and vulnerability of cholinergic neurons. Neurobiology of aging. vol 28. issue 1. 2006-12-28. PMID:16406151.' |
choline acetyl transferase activity was decreased in the cortex of dexamethasone-treated rats compared with controls. |
2006-12-28 |
2023-08-12 |
rat |
| S G Kalinichenko, Iu V Dudina, P A Motavki. [Neurogliaform cells: neurochemistry, spatial arrangement, and their role in the neocortical inhibitory system]. Tsitologiia. vol 48. issue 6. 2006-10-19. PMID:16893057. |
the neurogliaform cells (ngfc) localized in area 4 of the human motor cortex were found to express choline acetyl transferase (chat), gaba, and calbindin. |
2006-10-19 |
2023-08-12 |
human |
| Elizabeth A Donarum, Dietrich A Stephan, Kay Larkin, Eric J Murphy, Maneesh Gupta, Henry Senephansiri, Robert C Switzer, Phillip L Pearl, O Carter Snead, C Jakobs, K Michael Gibso. Expression profiling reveals multiple myelin alterations in murine succinate semialdehyde dehydrogenase deficiency. Journal of inherited metabolic disease. vol 29. issue 1. 2006-10-16. PMID:16601881. |
these results were confirmed by: (1) myelin basic protein (mbp) immunohistochemistry; (2) western blotting of myelin-associated glycoprotein (mag) and mbp; (3) qrt-pcr analyses of myelin-associated oligodendrocytic basic protein (mobp), mag, mbp and proteolipid protein (plp) in hippocampus, cortex and spinal cord; (4) quantitation of ethanolamine and choline plasmalogens, all core myelin components; (5) evaluation of myelin content in brain sections employing toluidine blue staining; and (6) ultrastructural evaluation of myelin sheath thickness via electron microscopy. |
2006-10-16 |
2023-08-12 |
mouse |
| S G Kalinichenko, I I Pushchin, I V Dyuize. Neurochemical diversity of neurogliaform cells in the human primary motor cortex. Journal of chemical neuroanatomy. vol 31. issue 4. 2006-08-11. PMID:16632327. |
neurogliaform cells of area 4 of the human motor cortex were found to express choline acetyl transferase (chat), gamma-aminobutyric acid, and calbindin. |
2006-08-11 |
2023-08-12 |
human |
| V Parikh, M Sarte. Cortical choline transporter function measured in vivo using choline-sensitive microelectrodes: clearance of endogenous and exogenous choline and effects of removal of cholinergic terminals. Journal of neurochemistry. vol 97. issue 2. 2006-06-08. PMID:16539662. |
ceramic-based microelectrodes, coated at recording sites with choline oxidase to detect extracellular choline concentration changes, were attached to multibarrel glass micropipettes and implanted into the rat frontoparietal cortex. |
2006-06-08 |
2023-08-12 |
rat |
| Francesco Amenta, Seyed Khosrow Tayebati, Daniela Vitali, Maria Antonietta Di Tulli. Association with the cholinergic precursor choline alphoscerate and the cholinesterase inhibitor rivastigmine: an approach for enhancing cholinergic neurotransmission. Mechanisms of ageing and development. vol 127. issue 2. 2006-04-21. PMID:16297435. |
choline alphoscerate or rivastigmine alone or in association, but not choline increased acetylcholine immunoreactivity in nerve fibers supplying cerebral cortex. |
2006-04-21 |
2023-08-12 |
rat |
| Takuya Fujita, Ayumi Shimada, Naoki Okada, Akira Yamamot. Functional characterization of Na+-independent choline transport in primary cultures of neurons from mouse cerebral cortex. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16239069. |
functional characterization of na+-independent choline transport in primary cultures of neurons from mouse cerebral cortex. |
2006-03-14 |
2023-08-12 |
mouse |
| Takuya Fujita, Ayumi Shimada, Naoki Okada, Akira Yamamot. Functional characterization of Na+-independent choline transport in primary cultures of neurons from mouse cerebral cortex. Neuroscience letters. vol 393. issue 2-3. 2006-03-14. PMID:16239069. |
we report here the functional characteristics of na+-independent choline transport system in primary cultures of neurons from mouse cerebral cortex. |
2006-03-14 |
2023-08-12 |
mouse |
| Sarah Garrod, Mary E Bollard, Andrew W Nicholls, Susan C Connor, John Connelly, Jeremy K Nicholson, Elaine Holme. Integrated metabonomic analysis of the multiorgan effects of hydrazine toxicity in the rat. Chemical research in toxicology. vol 18. issue 2. 2005-09-01. PMID:15720114. |
from histopathology measurements of liver tissue, minimal to mild hepatocyte alteration was observed in all animals at 24 h. the nmr spectra of the renal cortex at 24 h after dosing were dominated by a marked increase in the tissue concentration of 2-aminoadipate (2-aa) and beta-alanine, concomitant with depletions in tmao, myo-inositol, choline, taurine, glutamate, and lysine. |
2005-09-01 |
2023-08-12 |
rat |
| T M Tsang, J L Griffin, J Haselden, C Fish, E Holme. Metabolic characterization of distinct neuroanatomical regions in rats by magic angle spinning 1H nuclear magnetic resonance spectroscopy. Magnetic resonance in medicine. vol 53. issue 5. 2005-08-16. PMID:15844164. |
relatively low concentrations of gaba in the cerebellum, high concentrations of taurine and n-acetylaspartate in the cortex, and high levels of choline, glycerophosphocholine, and phosphocholine in the hippocampus predominantly influenced the classification of the different brain regions. |
2005-08-16 |
2023-08-12 |
rat |
| Adolf Pfefferbaum, Elfar Adalsteinsson, Edith V Sulliva. Cortical NAA deficits in HIV infection without dementia: influence of alcoholism comorbidity. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 7. 2005-08-09. PMID:15812566. |
we used mrsi with a variable-density spiral sequence to quantify major proton metabolites--n-acetylaspartate (naa), creatine (cr), and choline (cho)-in the superior parietal-occipital cortex. |
2005-08-09 |
2023-08-12 |
human |