| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ajeesh Koshy Cherian, Vinay Parikh, Qi Wu, Yang Mao-Draayer, Qin Wang, Randy D Blakely, Martin Sarte. Hemicholinium-3 sensitive choline transport in human T lymphocytes: Evidence for use as a proxy for brain choline transporter (CHT) capacity. Neurochemistry international. vol 108. 2018-04-13. PMID:28577989. |
to address the validity of t cell-based choline uptake as a proxy for brain cht capacity, we isolated t cells from the spleen, and synaptosomes from cortex and striatum, of wild type and cht-overexpressing mice (cht-oxp). |
2018-04-13 |
2023-08-13 |
mouse |
| Iñigo Murga, Virginia Guillen, José-Vicente Lafuent. Cerebral magnetic resonance changes associated with fibromyalgia syndrome. Medicina clinica. vol 148. issue 11. 2018-04-04. PMID:28450073. |
modifications in gray and white matter volume, as well as in levels of n-acetylaspartate, choline or glutamate, among other metabolites, have been observed in the hippocampus, insula, prefrontal and cingular cortex. |
2018-04-04 |
2023-08-13 |
Not clear |
| Shinji Yamashita, Michio Hashimoto, Abdul Md Haque, Kiyotaka Nakagawa, Mikio Kinoshita, Osamu Shido, Teruo Miyazaw. Oral Administration of Ethanolamine Glycerophospholipid Containing a High Level of Plasmalogen Improves Memory Impairment in Amyloid β-Infused Rats. Lipids. vol 52. issue 7. 2018-03-20. PMID:28551706. |
in addition, although there were no differences at levels of total plasmalogen including choline plasmalogen, the ascidian group had significantly higher levels of 18:0ol/22:6-plsetn in the cerebral cortex. |
2018-03-20 |
2023-08-13 |
rat |
| Jaivijay Ramu, Tetyana Konak, Serguei Liachenk. Magnetic resonance spectroscopic analysis of neurometabolite changes in the developing rat brain at 7T. Brain research. vol 1651. 2017-07-28. PMID:27663970. |
some differences between our data and the published literature were observed in the concentrations and dynamics of phosphocreatine, myo-inositol, and gaba in the hippocampus and creatine, gaba, glutamine, choline and n-acetyl-aspartate in the cortex. |
2017-07-28 |
2023-08-13 |
rat |
| Wojciech Durlak, Izabela Herman-Sucharska, Andrzej Urbanik, Małgorzata Klimek, Paulina Karcz, Grażyna Dutkowska, Magdalena Nitecka, Przemko Kwint. Relationship between Proton Magnetic Resonance Spectroscopy of Frontoinsular Gray Matter and Neurodevelopmental Outcomes in Very Low Birth Weight Children at the Age of 4. PloS one. vol 11. issue 5. 2017-07-10. PMID:27223474. |
lower concentrations of n-acetylaspartate (naa), choline (cho) and myoinositol (mi) were observed in the frontoinsular cortex of the left hemisphere in children with neurodevelopmental impairment compared to children with normal neurodevelopmental outcomes. |
2017-07-10 |
2023-08-13 |
Not clear |
| Xu Rui, Li Wenfang, Cheng Jing, Chen Meng, Ding Chengcheng, Xu Jiqu, Rong Shuan. Neuroprotective effects of phytosterol esters against high cholesterol-induced cognitive deficits in aged rat. Food & function. vol 8. issue 3. 2017-07-07. PMID:28256666. |
furthermore, pse improved cholinergic activities by restoring the acetylcholine (ach) content and decreasing acetylcholinesterase (ache) activity in the cerebral cortex, as well as by elevating choline acetyl transferase (chat) activity in the hippocampus and the cerebral cortex. |
2017-07-07 |
2023-08-13 |
rat |
| Yael Abreu-Villaça, Monique Correa-Santos, Ana C Dutra-Tavares, Danielle Paes-Branco, Andre Nunes-Freitas, Alex C Manhães, Cláudio C Filgueiras, Anderson Ribeiro-Carvalh. A ten fold reduction of nicotine yield in tobacco smoke does not spare the central cholinergic system in adolescent mice. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 52. 2017-03-27. PMID:27287270. |
the high-affinity choline transporter was reduced in the cortex: of highnic mice by the end of exposure; of both highnic and lownic females at short-term deprivation; of lownic mice at long-term deprivation. |
2017-03-27 |
2023-08-13 |
mouse |
| Yanyan Wang, Natalia Surzenko, Walter B Friday, Steven H Zeise. Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 4. 2016-08-23. PMID:26700730. |
however, the consequences of maternal dietary choline deficiency for the development and structural organization of the cerebral cortex remain unknown. |
2016-08-23 |
2023-08-13 |
mouse |
| Yanyan Wang, Natalia Surzenko, Walter B Friday, Steven H Zeise. Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 4. 2016-08-23. PMID:26700730. |
maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. |
2016-08-23 |
2023-08-13 |
mouse |
| Yanyan Wang, Natalia Surzenko, Walter B Friday, Steven H Zeise. Maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. FASEB journal : official publication of the Federation of American Societies for Experimental Biology. vol 30. issue 4. 2016-08-23. PMID:26700730. |
our findings describe a novel mechanism whereby low maternal dietary intake of choline alters brain development.-wang, y., surzenko, n., friday, w. b., zeisel, s. h. maternal dietary intake of choline in mice regulates development of the cerebral cortex in the offspring. |
2016-08-23 |
2023-08-13 |
mouse |
| Howard J Gritton, William M Howe, Caitlin S Mallory, Vaughn L Hetrick, Joshua D Berke, Martin Sarte. Cortical cholinergic signaling controls the detection of cues. Proceedings of the National Academy of Sciences of the United States of America. vol 113. issue 8. 2016-07-08. PMID:26787867. |
the discovery of phasic, trial-based increases in extracellular choline (transients), resulting from the hydrolysis of newly released acetylcholine (ach), in the cortex of animals reporting the presence of cues suggests that ach may have a more specialized role in cognitive processes. |
2016-07-08 |
2023-08-13 |
mouse |
| Sarah Doss, Jan Leo Rinnenthal, Tanja Schmitz-Hübsch, Alexander U Brandt, Sebastian Papazoglou, Silke Lux, Stephan Maul, Jens Würfel, Matthias Endres, Thomas Klockgether, Martina Minnerop, Friedemann Pau. Cerebellar neurochemical alterations in spinocerebellar ataxia type 14 appear to include glutathione deficiency. Journal of neurology. vol 262. issue 8. 2016-06-22. PMID:26041613. |
in the cerebellum and in additional vois in the prefrontal cortex, motor cortex, and somatosensory cortex, a second measurement was performed at te = 144 ms to mainly extract the total n-acetyl-aspartate (tnaa) signal besides the signals for total creatine (tcr) and total choline (tcho). |
2016-06-22 |
2023-08-13 |
Not clear |
| Gaelle S L Coullon, Uzay E Emir, Ione Fine, Kate E Watkins, Holly Bridg. Neurochemical changes in the pericalcarine cortex in congenital blindness attributable to bilateral anophthalmia. Journal of neurophysiology. vol 114. issue 3. 2016-06-17. PMID:26180125. |
more gray matter, combined with high levels of choline and myo-inositol, resembles the profile of the cortex at birth and suggests that the lack of visual input from the eyes might have delayed or arrested the maturation of this cortical region. |
2016-06-17 |
2023-08-13 |
human |
| O U Scremin, M Roch, K M Norman, S Djazayeri, Y-Y Li. Brain acetylcholine and choline concentrations and dynamics in a murine model of the Fragile X syndrome: age, sex and region-specific changes. Neuroscience. vol 301. 2016-04-18. PMID:26117713. |
brain endogenous ach (d0ach), free choline (d0ch), their deuterated variants d4ach and d4ch and mole ratios (achmr and chmr) were measured by gas chromatography-mass spectrometry in the cerebral hemisphere, cerebral cortex, hippocampus and cerebellum, following d4ch administration. |
2016-04-18 |
2023-08-13 |
mouse |
| Anouk Marsman, René C W Mandl, Dennis W J Klomp, Marc M Bohlken, Vincent O Boer, Anna Andreychenko, Wiepke Cahn, René S Kahn, Peter R Luijten, Hilleke E Hulshoff Po. GABA and glutamate in schizophrenia: a 7 T ¹H-MRS study. NeuroImage. Clinical. vol 6. 2015-07-07. PMID:25379453. |
no significant change in the gaba/cr ratio was found between patients and controls in the parieto-occipital cortex, nor were levels of glutamate, naa, creatine, and choline differed in patients and controls in the prefrontal and parieto-occipital cortices. |
2015-07-07 |
2023-08-13 |
Not clear |
| Daniel Serrani Azcurr. [Personality pathological traits and brain metabolites as predictors of non-abstinence in addicts with personality disorders]. Adicciones. vol 25. issue 3. 2014-07-30. PMID:23880833. |
for abstinent, choline levels were greater in cerebellar vermis and n-acetyl aspartate were lower in dorso-lateral prefrontal and anterior cingulated cortex and insula. |
2014-07-30 |
2023-08-12 |
human |
| Maggie Roy, Marie Hennebelle, Valérie St-Pierre, Alexandre Courchesne-Loyer, Mélanie Fortier, Anne-Karine Bouzier-Sore, Jean-Louis Gallis, Marie-Christine Beauvieux, Stephen C Cunnan. Long-term calorie restriction has minimal impact on brain metabolite and fatty acid profiles in aged rats on a Western-style diet. Neurochemistry international. vol 63. issue 5. 2014-06-02. PMID:23974047. |
high resolution magic angle spinning-(1)h nmr showed an effect of aging on brain cortex metabolites compared to 2al rats, the largest differences being for myo-inositol (+251% and +181%), lactate (+203% and +188%), β-hydroxybutyrate (+176% and +618%) and choline (+148% and +120%), in 19al and 19 cr rats, respectively. |
2014-06-02 |
2023-08-12 |
rat |
| Assawin Gongvatana, Jaroslaw Harezlak, Steven Buchthal, Eric Daar, Giovanni Schifitto, Thomas Campbell, Michael Taylor, Elyse Singer, Jeffrey Algers, Jianhui Zhong, Mark Brown, Deborah McMahon, Yuen T So, Deming Mi, Robert Heaton, Kevin Robertson, Constantin Yiannoutsos, Ronald A Cohen, Bradford Navi. Progressive cerebral injury in the setting of chronic HIV infection and antiretroviral therapy. Journal of neurovirology. vol 19. issue 3. 2014-01-24. PMID:23613008. |
concentrations of n-acetylaspartate (naa), creatine (cr), choline (cho), myoinositol, and glutamate/glutamine (glx) were measured in the midfrontal cortex (mfc), frontal white matter (fwm), and basal ganglia (bg). |
2014-01-24 |
2023-08-12 |
human |
| Yi Liu, Xia Tian, Lingshan Gou, Lingyan Sun, Xin Ling, Xiaoxing Yi. Luteolin attenuates diabetes-associated cognitive decline in rats. Brain research bulletin. vol 94. 2013-10-17. PMID:23415807. |
nissl's staining, choline esterase (che) activity as marker of cholinergic function and oxidative stress were assessed in the cerebral cortex and hippocampus to evaluate the neuropathological changes and the effects of luteolin on diabetic rats. |
2013-10-17 |
2023-08-12 |
rat |
| Annappa Poojary, P Mahaboob Bash. Cold stress interaction on organophosphate insecticide poisoning: age-related assessment in rat cerebral cortex. Indian journal of experimental biology. vol 50. issue 2. 2013-06-10. PMID:22670473. |
the present study was undertaken to identify the nature of the interactive effects of chlorpyrifos (cpf) and cold stress (15 degrees and 20 degrees c) on the activities of acetyl cholinesterase (ache), choline acetyl transferase (chat), na+, k(+)-atpase and malondialdehyde (mda) level in the cerebral cortex of 1 week, 3 weeks and 3 months of age. |
2013-06-10 |
2023-08-12 |
rat |