Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
S A Varvel, D T Bridgen, Q Tao, B F Thomas, B R Martin, A H Lichtma. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of pharmacology and experimental therapeutics. vol 314. issue 1. 2005-08-26. PMID:15831444. |
second, mice were exposed to smoke of an ethanol-extracted placebo plant material or low-grade marijuana (with minimal delta9-thc but similar levels of other cannabinoids) that were impregnated with varying quantities of delta9-thc. |
2005-08-26 |
2023-08-12 |
mouse |
S A Varvel, D T Bridgen, Q Tao, B F Thomas, B R Martin, A H Lichtma. Delta9-tetrahydrocannbinol accounts for the antinociceptive, hypothermic, and cataleptic effects of marijuana in mice. The Journal of pharmacology and experimental therapeutics. vol 314. issue 1. 2005-08-26. PMID:15831444. |
the present experiments provide evidence that the acute cannabinoid effects of marijuana smoke exposure on analgesia, hypothermia, and catalepsy in mice result from delta9-thc content acting at cb1 receptors and that the non-delta9-thc constituents of marijuana (at concentrations relevant to those typically consumed) influence these effects only minimally, if at all. |
2005-08-26 |
2023-08-12 |
mouse |
G E Boeckxstaen. [Cannabinoid hyperemesis with the unusual symptom of compulsive bathing]. Nederlands tijdschrift voor geneeskunde. vol 149. issue 26. 2005-08-25. PMID:16010960. |
after a recent publication on cannabinoid hyperemesis, the patient was questioned further, and it was found that he was a chronic cannabis smoker since the age of 14 years. |
2005-08-25 |
2023-08-12 |
Not clear |
M C Gye, H H Kang, H J Kan. Expression of cannabinoid receptor 1 in mouse testes. Archives of andrology. vol 51. issue 3. 2005-08-04. PMID:16025865. |
marijuana smoke and cannabinoids adversely affect male reproductive function in human and rodent through the cannabinoid receptors. |
2005-08-04 |
2023-08-12 |
mouse |
Christophe Hézode, Françoise Roudot-Thoraval, Son Nguyen, Pascale Grenard, Boris Julien, Elie-Serge Zafrani, Jean-Michel Pawlotsky, Jean-Michel Pawlostky, Daniel Dhumeaux, Sophie Lotersztajn, Ariane Malla. Daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis C. Hepatology (Baltimore, Md.). vol 42. issue 1. 2005-08-02. PMID:15892090. |
daily cannabis smoking as a risk factor for progression of fibrosis in chronic hepatitis c. cannabinoids present in cannabis sativa (marijuana) exert biological effects via cannabinoid receptors cb1 and cb2. |
2005-08-02 |
2023-08-12 |
Not clear |
Angelo Vaccani, Paola Massi, Arianna Colombo, Tiziana Rubino, Daniela Parolar. Cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism. British journal of pharmacology. vol 144. issue 8. 2005-07-29. PMID:15700028. |
cannabidiol inhibits human glioma cell migration through a cannabinoid receptor-independent mechanism. |
2005-07-29 |
2023-08-12 |
human |
M A Ware, H Adams, G W Gu. The medicinal use of cannabis in the UK: results of a nationwide survey. International journal of clinical practice. vol 59. issue 3. 2005-07-28. PMID:15857325. |
while caution must be exercised in interpreting these data, they point to the need for clinical studies of cannabis and cannabinoids with standardised and quality-controlled products. |
2005-07-28 |
2023-08-12 |
human |
V Di Marzo, L De Petrocellis, T Bisogn. Endocannabinoids Part I: molecular basis of endocannabinoid formation, action and inactivation and development of selective inhibitors. Expert opinion on therapeutic targets. vol 5. issue 2. 2005-07-19. PMID:15992179. |
the discovery of specific receptors for delta9-tetrahydrocannabinol, the major psychoactive component of marijuana, opened new horizons for the possible therapeutic exploitation of cannabis sativa and the cannabinoids. |
2005-07-19 |
2023-08-12 |
Not clear |
F Gambi, D De Berardis, G Sepede, R Quartesan, E Calcagni, R M Salerno, C M Conti, F M Ferr. Cannabinoid receptors and their relationships with neuropsychiatric disorders. International journal of immunopathology and pharmacology. vol 18. issue 1. 2005-07-14. PMID:15698507. |
cannabinoids are the constituents of the marijuana plants. |
2005-07-14 |
2023-08-12 |
Not clear |
A Holdcrof. Cannabinoids - from plant to patient. 5 April 2001, London, UK. IDrugs : the investigational drugs journal. vol 4. issue 7. 2005-07-13. PMID:15995932. |
the active constituents of cannabis (predominantly cannabinoids and possibly flavonoids) are more effective than a single cannabinoid in reducing muscle spasticity in a multiple sclerosis animal model. |
2005-07-13 |
2023-08-12 |
Not clear |
Isabel Lastres-Becker, Francisco Molina-Holgado, José A Ramos, Raphael Mechoulam, Javier Fernández-Rui. Cannabinoids provide neuroprotection against 6-hydroxydopamine toxicity in vivo and in vitro: relevance to Parkinson's disease. Neurobiology of disease. vol 19. issue 1-2. 2005-07-12. PMID:15837565. |
in addition, the fact that the same neuroprotective effect was also produced by cannabidiol (cbd), another plant-derived cannabinoid with negligible affinity for cannabinoid cb1 receptors, suggests that the antioxidant properties of both compounds, which are cannabinoid receptor-independent, might be involved in these in vivo effects, although an alternative might be that the neuroprotection exerted by both compounds might be due to their anti-inflammatory potential. |
2005-07-12 |
2023-08-12 |
mouse |
Susan Core. Recent developments in the therapeutic potential of cannabinoids. Puerto Rico health sciences journal. vol 24. issue 1. 2005-07-11. PMID:15895873. |
to examine the recent evidence that marijuana and other cannabinoids have therapeutic potential. |
2005-07-11 |
2023-08-12 |
Not clear |
C H Ashton, P B Moore, P Gallagher, A H Youn. Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. Journal of psychopharmacology (Oxford, England). vol 19. issue 3. 2005-06-27. PMID:15888515. |
we undertook a literature review of cannabis use by patients with bipolar disorder and of the neuropharmacological properties of cannabinoids suggesting possible therapeutic effects in this condition. |
2005-06-27 |
2023-08-12 |
Not clear |
C H Ashton, P B Moore, P Gallagher, A H Youn. Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. Journal of psychopharmacology (Oxford, England). vol 19. issue 3. 2005-06-27. PMID:15888515. |
no systematic studies of cannabinoids in bipolar disorder were found to exist, although some patients claim that cannabis relieves symptoms of mania and/or depression. |
2005-06-27 |
2023-08-12 |
Not clear |
C H Ashton, P B Moore, P Gallagher, A H Youn. Cannabinoids in bipolar affective disorder: a review and discussion of their therapeutic potential. Journal of psychopharmacology (Oxford, England). vol 19. issue 3. 2005-06-27. PMID:15888515. |
the cannabinoids delta(9)-tetrahydrocannabinol (thc) and cannabidiol (cbd) may exert sedative, hypnotic, anxiolytic, antidepressant, antipsychotic and anticonvulsant effects. |
2005-06-27 |
2023-08-12 |
Not clear |
Deepak Cyril D'Souza, Walid Michel Abi-Saab, Steven Madonick, Kimberlee Forselius-Bielen, Anne Doersch, Gabriel Braley, Ralitza Gueorguieva, Thomas B Cooper, John Harrison Krysta. Delta-9-tetrahydrocannabinol effects in schizophrenia: implications for cognition, psychosis, and addiction. Biological psychiatry. vol 57. issue 6. 2005-06-20. PMID:15780846. |
recent advances in the neurobiology of cannabinoids have renewed interest in the association between cannabis and psychotic disorders. |
2005-06-20 |
2023-08-12 |
Not clear |
Mario Galarreta, Ferenc Erdélyi, Gábor Szabó, Shaul Hestri. Electrical coupling among irregular-spiking GABAergic interneurons expressing cannabinoid receptors. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 24. issue 44. 2005-06-09. PMID:15525762. |
it has been proposed that these cells regulate rhythmic activity and play a key role mediating the cognitive actions of marijuana and endogenous cannabinoids. |
2005-06-09 |
2023-08-12 |
mouse |
J Ludovic Croxford, Stephen D Mille. Towards cannabis and cannabinoid treatment of multiple sclerosis. Drugs of today (Barcelona, Spain : 1998). vol 40. issue 8. 2005-06-07. PMID:15510238. |
towards cannabis and cannabinoid treatment of multiple sclerosis. |
2005-06-07 |
2023-08-12 |
human |
Maria M Medveczky, Tracy A Sherwood, Thomas W Klein, Herman Friedman, Peter G Medveczk. Delta-9 tetrahydrocannabinol (THC) inhibits lytic replication of gamma oncogenic herpesviruses in vitro. BMC medicine. vol 2. 2005-05-16. PMID:15369590. |
the major psychoactive cannabinoid compound of marijuana, delta-9 tetrahydrocannabinol (thc), has been shown to modulate immune responses and lymphocyte function. |
2005-05-16 |
2023-08-12 |
Not clear |
Samir A Ross, Mahmoud A ElSohly, Gazi N N Sultana, Zlatko Mehmedic, Chowdhury F Hossain, Suman Chandr. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Phytochemical analysis : PCA. vol 16. issue 1. 2005-05-09. PMID:15688956. |
flavonoid glycosides and cannabinoids from the pollen of cannabis sativa l. chemical investigation of the pollen grain collected from male plants of cannabis sativa l. resulted in the isolation for the first time of two flavonol glycosides from the methanol extract, and the identification of 16 cannabinoids in the hexane extract. |
2005-05-09 |
2023-08-12 |
Not clear |