| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| J Schaeffer, T Andrysiak, J T Ungerleide. Cognition and long-term use of ganja (Cannabis). Science (New York, N.Y.). vol 213. issue 4506. 1981-08-27. PMID:6972600. |
neuropsychological variables and urine cannabinoid metabolites were evaluated in ten subjects born, raised, and educated in the united states and having histories of heavy or prolonged use of cannabis. |
1981-08-27 |
2023-08-12 |
human |
| H K Borys, R Karle. Post-column derivatization procedure for the colorimetric analysis of tissue cannabinoids separated by high-performance liquid chromatography. Journal of chromatography. vol 205. issue 2. 1981-06-23. PMID:6260827. |
a new method for quantitating cannabidiol (cbd) and delta 9-tetrahydrocannabinol (thc) in mouse plasma and brain involves (1) the separation of cbd and thc from their major metabolites by the use of isocratic, reversed-phase high-performance liquid chromatography (hplc), and (2) the on-line reaction of the cannabinoids with fast blue salt b (fbb) as a the former elute from the column; the colored cannabinoid-fbb derivatives are then detected at 490 nm in a spectrophotometer with a sensitivity of less than 50 ng. |
1981-06-23 |
2023-08-12 |
mouse |
| H Lazaratou, A Moschovakis, A Armaganidis, V Kapsambelis, J Kiburis, T A Kephala. The pharmacological effect of fractions obtained by smoking cannabis through a water-pipe. II. A second fractionation step. Experientia. vol 36. issue 12. 1981-05-21. PMID:7202656. |
all but one of the cannabis fractions prolonged the pentobarbital sleeping-time and disrupted the nest-building activity of mice in a way not related to their content in the main cannabinoids. |
1981-05-21 |
2023-08-12 |
mouse |
| W G Drew, C R Weet, S E De Rossett, J R Bat. Effects of hippocampal brain damage on auditory and visual recent memory: comparison with marijuana-intoxicated subjects. Biological psychiatry. vol 15. issue 6. 1981-04-24. PMID:6257312. |
results are discussed in terms of cannabinoid actions on hippocampal functioning and, in general, support the hypothesis that the action of marijuana in the brain may focus in the hippocampal region and produce behavioral changes similar to that resulting from traumatic injury or removal of the region. |
1981-04-24 |
2023-08-12 |
human |
| D Maor, T Treves, A D Korczy. Lack of effect of cannabinoids on carbonic anhydrase. Journal of neural transmission. vol 49. issue 3. 1981-03-17. PMID:6256470. |
in order to investigate whether these actions of cannabinoids are mediated through inhibition of carbonic anhydrase (ca), commercial solutions of the enzyme were exposed to delta 9-tetrahydrocannabinol and cannabidiol. |
1981-03-17 |
2023-08-12 |
Not clear |
| C E Turner, O J Bouwsma, S Billets, M A Elsohl. Constituents of Cannabis sativa L. XVIII--Electron voltage selected ion monitoring study of cannabinoids. Biomedical mass spectrometry. vol 7. issue 6. 1981-01-29. PMID:7426688. |
constituents of cannabis sativa l. xviii--electron voltage selected ion monitoring study of cannabinoids. |
1981-01-29 |
2023-08-12 |
Not clear |
| H R Frischknecht, B Sieber, P G Wase. Behavioral effects of hashish in mice. II. Nursing behavior and development of the sucklings. Psychopharmacology. vol 70. issue 2. 1981-01-26. PMID:6776575. |
adult mice were treated from parturition to weaning of their first litter with a hashish extract containing 40% delta 9-tetrahydrocannabinol (delta 9-thc), 45% cannabidiol, 9% cannabinol, and 6% other cannabinoids. |
1981-01-26 |
2023-08-12 |
mouse |
| A T Charlebois, P A Frie. Interactive effects of nutrition and cannabis upon rat perinatal development. Developmental psychobiology. vol 13. issue 6. 1981-01-26. PMID:7429020. |
in order to examine the effects of cannabinoids, malnutrition, and their possible interaction upon the developing rat fetus, female wistar rats were exposed to cannabis smoke, placebo smoke, or no smoke while concurrently consuming 1 of 3 diets differing in protein concentration (8%, 24%, 64%). |
1981-01-26 |
2023-08-12 |
rat |
| P B Baker, R Fowler, K R Bagon, T A Goug. Determination of the distribution of cannabinoids in cannabis resin using high performance liquid chromatography. Journal of analytical toxicology. vol 4. issue 3. 1980-12-18. PMID:7421149. |
determination of the distribution of cannabinoids in cannabis resin using high performance liquid chromatography. |
1980-12-18 |
2023-08-12 |
Not clear |
| P B Baker, R Fowler, K R Bagon, T A Goug. Determination of the distribution of cannabinoids in cannabis resin using high performance liquid chromatography. Journal of analytical toxicology. vol 4. issue 3. 1980-12-18. PMID:7421149. |
cannabis resin from pakistan and lebanon was examined for the presence of these cannabinoids. |
1980-12-18 |
2023-08-12 |
Not clear |
| H Rosenkrantz, H J Esbe. Cannabinoid-induced hormone changes in monkeys and rats. Journal of toxicology and environmental health. vol 6. issue 2. 1980-09-28. PMID:6248648. |
previous findings at various laboratories indicated that cannabinoids distribute to sexual behavior centers in the brain, and endocrine aberrations have consistently been observed in animals treated with cannabis constituents. |
1980-09-28 |
2023-08-12 |
rat |
| B J Gudzinowicz, M J Gudzinowicz, J Hologgitas, J L Driscol. The analysis of marijuana cannabinoids and their metabolites in biological media by GC and/or GC-MS techniques. Advances in chromatography. vol 18. 1980-09-26. PMID:6249094. |
the analysis of marijuana cannabinoids and their metabolites in biological media by gc and/or gc-ms techniques. |
1980-09-26 |
2023-08-12 |
Not clear |
| A J Ganz, P G Wase. [Testing the pharmacological activity of some synthetic cannabinoids in mice (author's transl)]. Arzneimittel-Forschung. vol 30. issue 3. 1980-08-15. PMID:7387758. |
a series of synthetic cannabinoids were tested in mice for analgesic, anticonvulsant, sedative and reserpine antagonistic properties as well as for influence on body temperature and on motor coordination and compared with the natural delta 9-tetrahydrocannabinol (delta 9-thc), delta 8-tetrahydrocannabinol (delta 8-thc) and cannabidiol (cbd). |
1980-08-15 |
2023-08-12 |
mouse |
| B I Field, R R Arnd. Cannabinoid compounds in South African Cannabis sativa L. The Journal of pharmacy and pharmacology. vol 32. issue 1. 1980-05-14. PMID:6102121. |
cannabinoid compounds in south african cannabis sativa l. dagga (cannabis sativa l.) samples were collected from various geographical regions of south africa. |
1980-05-14 |
2023-08-12 |
Not clear |
| B I Field, R R Arnd. Cannabinoid compounds in South African Cannabis sativa L. The Journal of pharmacy and pharmacology. vol 32. issue 1. 1980-05-14. PMID:6102121. |
analytical results show that there appears to be at least three chemovariants of cannabis sativa growing in south africa with respect to relative cannabinoid content. |
1980-05-14 |
2023-08-12 |
Not clear |
| C L McLaughlin, C A Baile, P E Bende. Cannabinols and feeding in sheep. Psychopharmacology. vol 64. issue 3. 1980-01-28. PMID:116274. |
marijuana, long used for the euphoria which results, recently has been found to stimulate hunger in humans but in several laboratory animals cannabinoids decrease food intake. |
1980-01-28 |
2023-08-11 |
Not clear |
| H K Borys, G B Ingall, R Karle. Development of tolerance to the prolongation of hexobarbitone sleeping time caused by cannabidiol. British journal of pharmacology. vol 67. issue 1. 1980-01-19. PMID:497524. |
1 the effects of acute and subacute cannabidiol (cbd) administration on hexobarbitone sleeping time and on some constituents of the hepatic microsomal drug-metabolizing system were assessed in the mouse.2 acutely administered cbd prolonged sleeping time; but with subacute treatment, tolerance to the effect rapidly developed.3 brain hexobarbitone concentration upon awakening was unchanged by either acute or subacute cbd treatment, which suggests that neither the prolongation of sleeping time nor the tolerance is the result of a change in sensitivity of the central nervous system to the barbiturate.4 acute cbd treatment increased the half-time of hexobarbitone in the brain, which returned toward normal with the development of tolerance.5 acutely, cbd caused a 30% decrease in hepatic cytochrome p-450 level; with tolerance, the cytochrome concentration returned to normal.6 the evidence suggests that the cbd-induced prolongation of barbiturate sleeping time and the tolerance to this effect are the result of changes in the rate of drug metabolism, which are related to changes in the amount of cytochrome p-450.7 the effects of cbd on the hepatic microsomal drug-metabolizing enzyme system are different from those attributed to skf 525-a and piperonyl butoxide because the cannabinoid does not decrease cytochrome p-450 quantitatively by complex formation, it does not produce a recovery overshoot in the cytochrome concentration and, finally, it does not cause an induction of the hexobarbitone-metabolizing enzymes. |
1980-01-19 |
2023-08-11 |
Not clear |
| E G Boeren, M A Elsohly, C E Turne. Cannabiripsol: a novel Cannabis constituent. Experientia. vol 35. issue 10. 1980-01-19. PMID:499397. |
cannabiripsol [(-) (6ar, 9s, 10s, 10ar)9,10-dihydroxy-hexahydrocannabinol] (1), a new cannabinoid was isolated from a south african cannabis variant. |
1980-01-19 |
2023-08-11 |
Not clear |
| K Narayanaswami, H C Golani, H L Bami, R D Da. Stability of Cannabis sativa L. samples and their extracts, on prolonged storage in Delhi. Bulletin on narcotics. vol 30. issue 4. 1979-12-18. PMID:258607. |
the percentage rate of change into cannabinoids (cannabidiol [cbd], tetrahydrocannabinol [thc] and cannabinol [cbn]) was higher in cannabis samples than in the extracts. |
1979-12-18 |
2023-08-11 |
Not clear |
| C E Turner, P C Cheng, L M Torres, M A Elsohl. Detection and analysis of paraquat in confiscated marijuana samples. Bulletin on narcotics. vol 30. issue 4. 1979-12-18. PMID:258606. |
the cannabinoids in paraquat positive cannabis samples were analysed. |
1979-12-18 |
2023-08-11 |
Not clear |