| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Consroe, P Martin, D Eisenstei. Anticonvulsant drug antagonism of delta9tetrahydrocannabinol-induced seizures in rabbits. Research communications in chemical pathology and pharmacology. vol 16. issue 1. 1977-04-15. PMID:841172. |
a population of new zealand white rabbits exhibit behavioral convulsions when given low doses of psychoactive cannabinoids of marijuana. |
1977-04-15 |
2023-08-11 |
Not clear |
| P A Frie. Short and long-term effects of pre-natal cannabis inhalation upon rat offspring. Psychopharmacology. vol 50. issue 3. 1977-02-26. PMID:826975. |
pregnant rats were exposed to cannabis smoke or smoke from material with cannabinoids removed on days 1-19 of gestation. |
1977-02-26 |
2023-08-11 |
rat |
| R N Smith, C G Vaugha. High-pressure liquid chromatography of cannabis. Quantitative analysis of acidic and neutral cannabinoids. Journal of chromatography. vol 129. 1977-02-24. PMID:12189. |
a reversed-phase high-pressure liquid chromatographic method has been developed for the simultaneous analysis of the acidic and neutral cannabinoids in cannabis. |
1977-02-24 |
2023-08-11 |
Not clear |
| H N Bhargav. Effect of some cannabinoids on naloxone-precipitated abstinence in morphine-dependent mice. Psychopharmacology. vol 49. issue 3. 1977-02-16. PMID:826944. |
the relative effectiveness of the cannabinoids in inhibiting morphine abstinence appeared to be in the following order: delta9-tetrahydrocannabinol greater than delta8-tetrahydrocannabinol greater than 11-hydroxy-delta8-tetrahydrocannabinol greater than cannabidiol greater than cannabinol. |
1977-02-16 |
2023-08-11 |
mouse |
| P Zeidenberg, R Bourdon, G G Naha. Marijuana intoxication by passive inhalation: documentation by detection of urinary metabolites. The American journal of psychiatry. vol 134. issue 1. 1977-02-16. PMID:831546. |
the detection of cannabinoids in the urine of this nonsmoker documents the previously anecdotal concept of the "contact high" and has implications for marijuana research and for precautions that may be necessary should marijuana become legal. |
1977-02-16 |
2023-08-11 |
human |
| P Martin, P Consro. Cannabinoid induced behavioral convulsions in rabbits. Science (New York, N.Y.). vol 194. issue 4268. 1977-01-03. PMID:982057. |
a population of new zealand white rabbits has been found to exhibit behavioral convulsions when given low intravenous doses of psychoactive cannabinoids of marijuana. |
1977-01-03 |
2023-08-11 |
Not clear |
| A R Chase, P R Kelley, A Taunton-Rigby, R T Jones, T Harwoo. Quantitation of cannabinoids in biological fluids by radioimmunoassay. NIDA research monograph. issue 7. 1976-11-21. PMID:987538. |
the assay is sufficiently sensitive to detect cannabinoids in the urine of marijuana smokers for several days after their last exposure to the drug. |
1976-11-21 |
2023-08-11 |
Not clear |
| A B Segelman, F P Segelma. Cannabis sativa L. (Marijuana). VII. The relative specificity of the RIM test. Journal of chromatography. vol 123. issue 1. 1976-10-02. PMID:950361. |
although a few samples gave fast blue b reactive spots when examined by thin-layer chromatography, the spots could easily be distinguished from the marijuana cannabinoid spots. |
1976-10-02 |
2023-08-11 |
Not clear |
| M Van Boven, N Bruneel, P Daenen. [Determination of cannabinoids in Cannabis sativa from Belgian origin (author's transl)]. Journal de pharmacie de Belgique. vol 31. issue 2. 1976-10-02. PMID:950586. |
[determination of cannabinoids in cannabis sativa from belgian origin (author's transl)]. |
1976-10-02 |
2023-08-11 |
Not clear |
| J W Fairbairn, J A Liebmann, M G Rowa. The stability of cannabis and its preparations on storage. The Journal of pharmacy and pharmacology. vol 28. issue 1. 1976-08-23. PMID:6643. |
solutions of pure cannabinoids, nine samples of herbal and two of resin cannabis (one freshly prepared) were stored in varying conditions for up to 2 years. |
1976-08-23 |
2023-08-11 |
Not clear |
| R A Carchman, L S Harris, A E Munso. The inhibition of DNA synthesis by cannabinoids. Cancer research. vol 36. issue 1. 1976-04-27. PMID:1248011. |
inhibition of dna synthesis as measured by [3h]thymidine uptake into acid-insoluble material was used as an index of cannabinoid activity against isolated lewis lung cells, l1210 leukemia cells, and bone marrow cells incubated in vitro delta9-, delta8-, 1-hydroxy-3-n pentyl-, and 1-delta8-tetrahydrocannabinol, and cannabinol demonstrated a dose-dependent inhibition of dna synthesis whereas cannabidiol and 1-hydroxy-3-n-pentylcannabidiol were markedly less inhibitory in our in vitro cell systems. |
1976-04-27 |
2023-08-11 |
mouse |
| J W Fairbairn, M G Rowa. Proceedings: Cannabinoid pattern in Cannabis sativa L. seedlings as an indication of chemical race. The Journal of pharmacy and pharmacology. vol 27 Suppl?-2. 1976-04-15. PMID:2769. |
proceedings: cannabinoid pattern in cannabis sativa l. seedlings as an indication of chemical race. |
1976-04-15 |
2023-08-11 |
Not clear |
| P Chiu, R Karler, C Craven, D M Olsen, S A Turkani. The influence of delta9-tetrahydrocannabinol, cannabinol and cannabidiol on tissue oxygen consumption. Research communications in chemical pathology and pharmacology. vol 12. issue 2. 1976-02-09. PMID:1197914. |
the mechanism of the hypothermia produced in mice by the naturally occurring cannabinoids, delta9-tetrahydrocannabinol, cannabinol, and cannabidiol, was investigated by evaluating the direct effect of these drugs on the oxygen consumption of tissue homogenates and isolated mitochondria. |
1976-02-09 |
2023-08-11 |
mouse |
| B Hine, M Torrelio, S Gersho. Differential effect of cannabinol and cannabidiol on THC-induced responses during abstinence in morphine-dependent rats. Research communications in chemical pathology and pharmacology. vol 12. issue 1. 1976-01-26. PMID:1237925. |
these data illustrate differences between psychoinactive cannabinoids in their interaction with delta 9-thc that might be relevant to possible clinical use of cannabis in narcotic detoxification. |
1976-01-26 |
2023-08-11 |
rat |
| J D Teale, J M Clough, E M Piall, L J King, V Mark. Plasma cannabinoids measured by radioimmunoassay in rabbits after intravenous injection of tetrahydrocannibinol, 11-hydroxy-tetrahydrocannabinol, cannabinol and cannabidiol. Research communications in chemical pathology and pharmacology. vol 11. issue 2. 1975-11-06. PMID:1153879. |
plasma cannabinoids measured by radioimmunoassay in rabbits after intravenous injection of tetrahydrocannibinol, 11-hydroxy-tetrahydrocannabinol, cannabinol and cannabidiol. |
1975-11-06 |
2023-08-11 |
cattle |
| J D Teale, J M Clough, E M Piall, L J King, V Mark. Plasma cannabinoids measured by radioimmunoassay in rabbits after intravenous injection of tetrahydrocannibinol, 11-hydroxy-tetrahydrocannabinol, cannabinol and cannabidiol. Research communications in chemical pathology and pharmacology. vol 11. issue 2. 1975-11-06. PMID:1153879. |
an antiserum raised in sheep against a conjugate of tetrahydrocannabinol with bovine serum albumin has been used as the basis of a radioimmunoassay for cannabinoids in the blood of rabbits given tetrahydrocannabinol, 11-hydroxy-tetrahydrocannabinol, cannabinol or cannabidiol by rapid intravenous injection. |
1975-11-06 |
2023-08-11 |
cattle |
| C E Turner, K W Hadley, J H Holley, S Billets, M L Mol. Constituents of Cannabis sativa L. VIII: Possible biological application of a new method to separate cannabidiol and cannabichromene. Journal of pharmaceutical sciences. vol 64. issue 5. 1975-10-30. PMID:1151651. |
biological interaction among (minus)-delta9-trans-tetrhydrocanabinol, cannabichromene, and other cannabinoids in natural cannabis preparations can now be studied. |
1975-10-30 |
2023-08-11 |
Not clear |
| K E Rasmusse. Analysis of cannabinoids in cannabis by means of gas-liquid chromatography and soild injection. Improvements to the method. Journal of chromatography. vol 109. issue 1. 1975-09-09. PMID:1138002. |
analysis of cannabinoids in cannabis by means of gas-liquid chromatography and soild injection. |
1975-09-09 |
2023-08-11 |
Not clear |
| C E Turner, J T Henr. Constituents of Cannabis sativa L. IX: Stability of synthetic and naturally occurring cannabinoids in chloroform. Journal of pharmaceutical sciences. vol 64. issue 2. 1975-08-04. PMID:1127600. |
constituents of cannabis sativa l. ix: stability of synthetic and naturally occurring cannabinoids in chloroform. |
1975-08-04 |
2023-08-11 |
Not clear |
| G B Chesher, D M Jackson, G A Starme. Interaction of cannabis and general anaesthetic agents in mice. British journal of pharmacology. vol 50. issue 4. 1975-05-21. PMID:4280927. |
after eight consecutive daily doses of cannabis, the pentobarbitone anaesthesia was still significantly longer than a control group, while ether anaesthesia was not significantly prolonged.3 a second cannabis extract (ii) with a different ratio of cannabinoids (also administered in dosage equivalent to 10 mg delta(9)-thc/kg) failed to affect pentobarbitone anaesthesia in mice. |
1975-05-21 |
2023-08-11 |
mouse |