| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Samir A Ross, Mahmoud A ElSohly, Gazi N N Sultana, Zlatko Mehmedic, Chowdhury F Hossain, Suman Chandr. Flavonoid glycosides and cannabinoids from the pollen of Cannabis sativa L. Phytochemical analysis : PCA. vol 16. issue 1. 2005-05-09. PMID:15688956. |
the identified cannabinoids were delta9-tetrahydrocannabiorcol, cannabidivarin, cannabicitran, delta9-tetrahydrocannabivarin, cannabicyclol, cannabidiol, cannabichromene, delta9-tetrahydrocannabinol, cannabigerol, cannabinol, dihydrocannabinol, cannabielsoin, 6a, 7, 10a-trihydroxytetrahydrocannabinol, 9, 10-epoxycannabitriol, 10-o-ethylcannabitriol, and 7, 8-dehydro-10-o-ethylcannabitriol. |
2005-05-09 |
2023-08-12 |
Not clear |
| Ester Fride, Cfir Feigin, Datta E Ponde, Aviva Breuer, Lumír Hanus, Nina Arshavsky, Raphael Mechoula. (+)-Cannabidiol analogues which bind cannabinoid receptors but exert peripheral activity only. European journal of pharmacology. vol 506. issue 2. 2005-05-06. PMID:15588739. |
delta9-tetrahydrocannabinol (delta9-thc) and (-)-cannabidiol are major constituents of the cannabis sativa plant with different pharmacological profiles: (-)-delta9-tetrahydrocannabinol, but not (-)-cannabidiol, activates cannabinoid cb1 and cb2 receptors and induces psychoactive and peripheral effects. |
2005-05-06 |
2023-08-12 |
mouse |
| Takayuki Sugiura, Saori Oka, Maiko Gokoh, Seishi Kishimoto, Keizo Wak. New perspectives in the studies on endocannabinoid and cannabis: 2-arachidonoylglycerol as a possible novel mediator of inflammation. Journal of pharmacological sciences. vol 96. issue 4. 2005-04-28. PMID:15599096. |
new perspectives in the studies on endocannabinoid and cannabis: 2-arachidonoylglycerol as a possible novel mediator of inflammation. |
2005-04-28 |
2023-08-12 |
mouse |
| Tsuneyuki Yamamoto, Kusnandar Anggadiredja, Takato Hiranit. New perspectives in the studies on endocannabinoid and cannabis: a role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking. Journal of pharmacological sciences. vol 96. issue 4. 2005-04-28. PMID:15599102. |
new perspectives in the studies on endocannabinoid and cannabis: a role for the endocannabinoid-arachidonic acid pathway in drug reward and long-lasting relapse to drug taking. |
2005-04-28 |
2023-08-12 |
Not clear |
| Michihiro Fujiwara, Nobuaki Egashir. New perspectives in the studies on endocannabinoid and cannabis: abnormal behaviors associate with CB1 cannabinoid receptor and development of therapeutic application. Journal of pharmacological sciences. vol 96. issue 4. 2005-04-28. PMID:15599103. |
new perspectives in the studies on endocannabinoid and cannabis: abnormal behaviors associate with cb1 cannabinoid receptor and development of therapeutic application. |
2005-04-28 |
2023-08-12 |
rat |
| Hiroshi Ujike, Yukitaka Morit. New perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia. Journal of pharmacological sciences. vol 96. issue 4. 2005-04-28. PMID:15613777. |
new perspectives in the studies on endocannabinoid and cannabis: cannabinoid receptors and schizophrenia. |
2005-04-28 |
2023-08-12 |
Not clear |
| Robert J McKallip, Mitzi Nagarkatti, Prakash S Nagarkatt. Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 6. 2005-04-28. PMID:15749859. |
in the current study, we tested the central hypothesis that exposure to delta-9-tetrahydrocannabinol (delta9-thc), the major psychoactive component in marijuana, can lead to enhanced growth of tumors that express low to undetectable levels of cannabinoid receptors by specifically suppressing the antitumor immune response. |
2005-04-28 |
2023-08-12 |
mouse |
| Robert J McKallip, Mitzi Nagarkatti, Prakash S Nagarkatt. Delta-9-tetrahydrocannabinol enhances breast cancer growth and metastasis by suppression of the antitumor immune response. Journal of immunology (Baltimore, Md. : 1950). vol 174. issue 6. 2005-04-28. PMID:15749859. |
such findings suggest that marijuana exposure either recreationally or medicinally may increase the susceptibility to and/or incidence of breast cancer as well as other cancers that do not express cannabinoid receptors and are resistant to delta9-thc-induced apoptosis. |
2005-04-28 |
2023-08-12 |
mouse |
| Ester Fride, Tatyana Bregman, Tim C Kirkha. Endocannabinoids and food intake: newborn suckling and appetite regulation in adulthood. Experimental biology and medicine (Maywood, N.J.). vol 230. issue 4. 2005-04-28. PMID:15792943. |
investigations into the biological basis of the multiple effects of cannabis have yielded important breakthroughs in recent years: the discovery of two cannabinoid receptors in brain and peripheral organ systems, and endogenous ligands (endocannabinoids) for these receptors. |
2005-04-28 |
2023-08-12 |
Not clear |
| Barbara Costa, Gabriella Giagnoni, Chiara Franke, Anna Elisa Trovato, Mariapia Colleon. Vanilloid TRPV1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15313881. |
vanilloid trpv1 receptor mediates the antihyperalgesic effect of the nonpsychoactive cannabinoid, cannabidiol, in a rat model of acute inflammation. |
2005-04-22 |
2023-08-12 |
rat |
| Carl R Lupica, Arthur C Riegel, Alexander F Hoffma. Marijuana and cannabinoid regulation of brain reward circuits. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15313883. |
marijuana and cannabinoid regulation of brain reward circuits. |
2005-04-22 |
2023-08-12 |
Not clear |
| Carl R Lupica, Arthur C Riegel, Alexander F Hoffma. Marijuana and cannabinoid regulation of brain reward circuits. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15313883. |
the psychoactive properties of marijuana are mediated by the active constituent, delta(9)-thc, interacting primarily with cb1 cannabinoid receptors in a large number of brain areas. |
2005-04-22 |
2023-08-12 |
Not clear |
| Carl R Lupica, Arthur C Riegel, Alexander F Hoffma. Marijuana and cannabinoid regulation of brain reward circuits. British journal of pharmacology. vol 143. issue 2. 2005-04-22. PMID:15313883. |
in addition, we compare the effects of delta(9)-thc with those of other commonly abused drugs on these reward circuits, and we discuss the roles that endogenous cannabinoids may play within these brain pathways, and their possible involvement in regulating ongoing brain function, independently of marijuana consumption. |
2005-04-22 |
2023-08-12 |
Not clear |
| Sachin Patel, Benjamin F Cravatt, Cecilia J Hillar. Synergistic interactions between cannabinoids and environmental stress in the activation of the central amygdala. Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology. vol 30. issue 3. 2005-04-21. PMID:15280883. |
these data suggest the cea is an important neural substrate subserving the interactions between cannabinoids and environmental stress, and could be relevant to understanding the context-dependent emotional and affective changes induced by marijuana intoxication and the role of endocannabinoid signaling in the modulation of amygdalar activity. |
2005-04-21 |
2023-08-12 |
mouse |
| Sami Sarfaraz, Farrukh Afaq, Vaqar M Adhami, Hasan Mukhta. Cannabinoid receptor as a novel target for the treatment of prostate cancer. Cancer research. vol 65. issue 5. 2005-04-19. PMID:15753356. |
cannabinoids, the active components of cannabis sativa linnaeus (marijuana) and their derivatives have received renewed interest in recent years due to their diverse pharmacologic activities such as cell growth inhibition, anti-inflammatory effects and tumor regression. |
2005-04-19 |
2023-08-12 |
human |
| Gabrielle L McLemore, Reed Z B Cooper, Kimberlei A Richardson, Ariel V Mason, Cathleen Marshall, Frances J Northington, Estelle B Gaud. Cannabinoid receptor expression in peripheral arterial chemoreceptors during postnatal development. Journal of applied physiology (Bethesda, Md. : 1985). vol 97. issue 4. 2005-04-18. PMID:15358754. |
to determine whether marijuana could potentially affect the activity of peripheral arterial chemoreceptors during early postnatal development, we used in situ hybridization histochemistry to characterize the pattern and level of mrna expression for cannabinoid type 1 receptor (cb1r) in the carotid body, superior cervical ganglia (scg), and nodose-petrosal-jugular ganglia (ng-pg-jg) complex in newborn rats. |
2005-04-18 |
2023-08-12 |
rat |
| F Rodríguez De Fonseca, M A Gorriti, A Bilbao, L Escuredo, L M García-Segura, D Piomelli, M Navarr. Role of the endogenous cannabinoid system as a modulator of dopamine transmission: implications for Parkinson's disease and schizophrenia. Neurotoxicity research. vol 3. issue 1. 2005-04-12. PMID:15111259. |
this system is the target of natural cannabinoids, the psychoactive constituents of cannabis sativa preparations (marijuana, hashish). |
2005-04-12 |
2023-08-12 |
rat |
| A A M Stolker, J van Schoonhoven, A J de Vries, I Bobeldijk-Pastorova, W H J Vaes, R van den Ber. Determination of cannabinoids in cannabis products using liquid chromatography-ion trap mass spectrometry. Journal of chromatography. A. vol 1058. issue 1-2. 2005-04-12. PMID:15595662. |
determination of cannabinoids in cannabis products using liquid chromatography-ion trap mass spectrometry. |
2005-04-12 |
2023-08-12 |
Not clear |
| A A M Stolker, J van Schoonhoven, A J de Vries, I Bobeldijk-Pastorova, W H J Vaes, R van den Ber. Determination of cannabinoids in cannabis products using liquid chromatography-ion trap mass spectrometry. Journal of chromatography. A. vol 1058. issue 1-2. 2005-04-12. PMID:15595662. |
the cannabinoids were extracted from the grinded cannabis samples with a mixture of methanol-chloroform and analysed using liquid chromatography with ion-trap-mass-spectrometry (lc-it-msn). |
2005-04-12 |
2023-08-12 |
Not clear |
| Kazuhide Hayakawa, Kenichi Mishima, Kohji Abe, Nobuyoshi Hasebe, Fumie Takamatsu, Hiromi Yasuda, Tomoaki Ikeda, Keiichiro Inui, Nobuaki Egashira, Katsunori Iwasaki, Michihiro Fujiwar. Cannabidiol prevents infarction via the non-CB1 cannabinoid receptor mechanism. Neuroreport. vol 15. issue 15. 2005-04-08. PMID:15640760. |
the neuroprotective effects of delta(9)-tetrahydrocannabinol but not cannabidiol were inhibited by sr141716, a cannabinoid cb1 receptor antagonist, and were abolished by warming of the animals to the levels observed in the controls. |
2005-04-08 |
2023-08-12 |
mouse |