| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| David M Schwope, Karl B Scheidweiler, Marilyn A Huesti. Direct quantification of cannabinoids and cannabinoid glucuronides in whole blood by liquid chromatography-tandem mass spectrometry. Analytical and bioanalytical chemistry. vol 401. issue 4. 2012-01-11. PMID:21727996. |
this new analytical method should be useful for quantifying cannabinoids in whole blood and further investigating cannabinoid glucuronides as markers of recent cannabis intake. |
2012-01-11 |
2023-08-12 |
Not clear |
| David A Gorelick, Robert S Goodwin, Eugene Schwilke, David M Schwope, William D Darwin, Deanna L Kelly, Robert P McMahon, Fang Liu, Catherine Ortemann-Renon, Denis Bonnet, Marilyn A Huesti. Antagonist-elicited cannabis withdrawal in humans. Journal of clinical psychopharmacology. vol 31. issue 5. 2011-12-27. PMID:21869692. |
cannabinoid cb1 receptor antagonists have potential therapeutic benefits, but antagonist-elicited cannabis withdrawal has not been reported in humans. |
2011-12-27 |
2023-08-12 |
human |
| Gregory T Carter, Aaron M Flanagan, Mitchell Earleywine, Donald I Abrams, Sunil K Aggarwal, Lester Grinspoo. Cannabis in palliative medicine: improving care and reducing opioid-related morbidity. The American journal of hospice & palliative care. vol 28. issue 5. 2011-12-16. PMID:21444324. |
cannabis contains 20% thc or less but has other therapeutic cannabinoids, all working together to produce therapeutic effects. |
2011-12-16 |
2023-08-12 |
Not clear |
| Erik Keimpema, Ken Mackie, Tibor Harkan. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in pharmacological sciences. vol 32. issue 9. 2011-12-14. PMID:21757242. |
cannabis impacts the formation and functions of neuronal circuitries by targeting cannabinoid receptors. |
2011-12-14 |
2023-08-12 |
Not clear |
| Erik Keimpema, Ken Mackie, Tibor Harkan. Molecular model of cannabis sensitivity in developing neuronal circuits. Trends in pharmacological sciences. vol 32. issue 9. 2011-12-14. PMID:21757242. |
by indiscriminately prolonging the 'switched-on' period of cannabinoid receptors, cannabis can hijack endocannabinoid signals to evoke molecular rearrangements, leading to the erroneous wiring of neuronal networks. |
2011-12-14 |
2023-08-12 |
Not clear |
| Jenny L Wiley, D Matthew Walentiny, Robert E Vann, Cassandra Y Baskfiel. Dissimilar cannabinoid substitution patterns in mice trained to discriminate Δ(9)-tetrahydrocannabinol or methanandamide from vehicle. Behavioural pharmacology. vol 22. issue 5-6. 2011-12-13. PMID:21712709. |
these results suggest incomplete overlap in the underlying mechanisms mediating endocannabinoid pharmacology and marijuana intoxication. |
2011-12-13 |
2023-08-12 |
mouse |
| David M Schwope, Erin L Karschner, David A Gorelick, Marilyn A Huesti. Identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration. Clinical chemistry. vol 57. issue 10. 2011-12-07. PMID:21836075. |
identification of recent cannabis use: whole-blood and plasma free and glucuronidated cannabinoid pharmacokinetics following controlled smoked cannabis administration. |
2011-12-07 |
2023-08-12 |
Not clear |
| Justin L Poklis, Candace C Thompson, Kelly A Long, Aron H Lichtman, Alphonse Pokli. Disposition of cannabichromene, cannabidiol, and Δ⁹-tetrahydrocannabinol and its metabolites in mouse brain following marijuana inhalation determined by high-performance liquid chromatography-tandem mass spectrometry. Journal of analytical toxicology. vol 34. issue 8. 2011-12-06. PMID:21258613. |
a liquid chromatography-tandem mass spectrometry (lc-ms-ms)method was developed for the analysis of marijuana cannabinoids in mouse brain tissue using an applied biosystems 3200 q trap with a turbo v source for turbolonspray attached to a shimadzu scl hplc system. |
2011-12-06 |
2023-08-12 |
mouse |
| Justin L Poklis, Candace C Thompson, Kelly A Long, Aron H Lichtman, Alphonse Pokli. Disposition of cannabichromene, cannabidiol, and Δ⁹-tetrahydrocannabinol and its metabolites in mouse brain following marijuana inhalation determined by high-performance liquid chromatography-tandem mass spectrometry. Journal of analytical toxicology. vol 34. issue 8. 2011-12-06. PMID:21258613. |
the relative mean brain cannabinoid concentrations correlated to the amounts of the cannabinoids in the inhaled marijuana. |
2011-12-06 |
2023-08-12 |
mouse |
| M Shabani, N Hosseinmardi, M Haghani, V Shaibani, M Janahmad. Maternal exposure to the CB1 cannabinoid agonist WIN 55212-2 produces robust changes in motor function and intrinsic electrophysiological properties of cerebellar Purkinje neurons in rat offspring. Neuroscience. vol 172. 2011-12-05. PMID:20969930. |
marijuana, cannabinoids). |
2011-12-05 |
2023-08-12 |
rat |
| Zuzana Justinová, Sergi Ferré, Godfrey H Redhi, Paola Mascia, Jessica Stroik, Davide Quarta, Sevil Yasar, Christa E Müller, Rafael Franco, Steven R Goldber. Reinforcing and neurochemical effects of cannabinoid CB1 receptor agonists, but not cocaine, are altered by an adenosine A2A receptor antagonist. Addiction biology. vol 16. issue 3. 2011-12-02. PMID:21054689. |
however, the appearance of potentiating rather than suppressing effects on cannabinoid reinforcement at the higher dose of msx-3 would likely preclude the use of such a compound as a medication for cannabis abuse. |
2011-12-02 |
2023-08-12 |
rat |
| George W Boo. Cannabidiol as an emergent therapeutic strategy for lessening the impact of inflammation on oxidative stress. Free radical biology & medicine. vol 51. issue 5. 2011-12-02. PMID:21238581. |
in this context, the related nonpsychotropic cannabinoid cannabidiol, which may interact with the endocannabinoid system but has actions that are distinct, offers promise as a prototype for anti-inflammatory drug development. |
2011-12-02 |
2023-08-12 |
human |
| Cindy L Moran, Vi-Huyen Le, Krishna C Chimalakonda, Amy L Smedley, Felisia D Lackey, Suzanne N Owen, Paul D Kennedy, Gregory W Endres, Fred L Ciske, James B Kramer, Andrei M Kornilov, L D Bratton, Paul J Dobrowolski, William D Wessinger, William E Fantegrossi, Paul L Prather, Laura P James, Anna Radominska-Pandya, Jeffery H Mora. Quantitative measurement of JWH-018 and JWH-073 metabolites excreted in human urine. Analytical chemistry. vol 83. issue 11. 2011-12-01. PMID:21506519. |
"k2/spice" products are commonly laced with aminoalkylindole synthetic cannabinoids (i.e., jwh-018 and jwh-073) and are touted as "legal" marijuana substitutes. |
2011-12-01 |
2023-08-12 |
human |
| Neta Rimmerman, Ana Juknat, Ewa Kozela, Rivka Levy, Heather B Bradshaw, Zvi Voge. The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells. Cellular and molecular neurobiology. vol 31. issue 6. 2011-11-30. PMID:21533611. |
the non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells. |
2011-11-30 |
2023-08-12 |
Not clear |
| Neta Rimmerman, Ana Juknat, Ewa Kozela, Rivka Levy, Heather B Bradshaw, Zvi Voge. The non-psychoactive plant cannabinoid, cannabidiol affects cholesterol metabolism-related genes in microglial cells. Cellular and molecular neurobiology. vol 31. issue 6. 2011-11-30. PMID:21533611. |
cannabidiol (cbd) is a non-psychoactive plant cannabinoid that is clinically used in a 1:1 mixture with the psychoactive cannabinoid Δ(9)-tetrahydrocannabinol (thc) for the treatment of neuropathic pain and spasticity in multiple sclerosis. |
2011-11-30 |
2023-08-12 |
Not clear |
| Federica Pollastro, Orazio Taglialatela-Scafati, Marco Allarà, Eduardo Muñoz, Vincenzo Di Marzo, Luciano De Petrocellis, Giovani Appendin. Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa). Journal of natural products. vol 74. issue 9. 2011-11-28. PMID:21902175. |
bioactive prenylogous cannabinoid from fiber hemp (cannabis sativa). |
2011-11-28 |
2023-08-12 |
Not clear |
| Federica Pollastro, Orazio Taglialatela-Scafati, Marco Allarà, Eduardo Muñoz, Vincenzo Di Marzo, Luciano De Petrocellis, Giovani Appendin. Bioactive prenylogous cannabinoid from fiber hemp (Cannabis sativa). Journal of natural products. vol 74. issue 9. 2011-11-28. PMID:21902175. |
the waxy fraction from the variety carma of fiber hemp (cannabis sativa) afforded the unusual cannabinoid 4, identified as the farnesyl prenylogue of cannabigerol (cbg, 1) on the basis of its spectroscopic properties. |
2011-11-28 |
2023-08-12 |
Not clear |
| Garry Milman, Allan J Barnes, David M Schwope, Eugene W Schwilke, Robert S Goodwin, Deana L Kelly, David A Gorelick, Marilyn A Huesti. Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration. Analytical and bioanalytical chemistry. vol 401. issue 2. 2011-11-23. PMID:21637933. |
expectorated of specimens (n = 360) were obtained from 10 adult daily cannabis smokers before, during, and after 37 20-mg oral Δ(9)-tetrahydrocannabinol (thc) doses over 9 days to characterize cannabinoid disposition in this matrix. |
2011-11-23 |
2023-08-12 |
Not clear |
| Garry Milman, Allan J Barnes, David M Schwope, Eugene W Schwilke, Robert S Goodwin, Deana L Kelly, David A Gorelick, Marilyn A Huesti. Cannabinoids and metabolites in expectorated oral fluid after 8 days of controlled around-the-clock oral THC administration. Analytical and bioanalytical chemistry. vol 401. issue 2. 2011-11-23. PMID:21637933. |
measurement of thccooh may improve the detection and interpretation of of cannabinoid tests and minimize the possibility of of contamination from passive inhalation of cannabis smoke. |
2011-11-23 |
2023-08-12 |
Not clear |
| E S Onaiv. Commentary: Functional Neuronal CB2 Cannabinoid Receptors in the CNS. Current neuropharmacology. vol 9. issue 1. 2011-11-10. PMID:21886591. |
cannabinoids are the constituents of the marijuana plant (cannabis sativa). |
2011-11-10 |
2023-08-12 |
human |