| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Muraki, T Koyama, M Nakayama, T Ohmori, I Yamashit. MK-801, a non-competitive antagonist of NMDA receptor, prevents methamphetamine-induced decrease of striatal dopamine uptake sites in the rat striatum. Neuroscience letters. vol 136. issue 1. 1992-08-24. PMID:1353257. |
mk-801, a non-competitive antagonist of nmda receptor, prevents methamphetamine-induced decrease of striatal dopamine uptake sites in the rat striatum. |
1992-08-24 |
2023-08-11 |
rat |
| A Muraki, T Koyama, M Nakayama, T Ohmori, I Yamashit. MK-801, a non-competitive antagonist of NMDA receptor, prevents methamphetamine-induced decrease of striatal dopamine uptake sites in the rat striatum. Neuroscience letters. vol 136. issue 1. 1992-08-24. PMID:1353257. |
we investigated the effects of mk-801, a non-competitive antagonist of nmda receptor, on methamphetamine-induced decrease in dopamine (da) uptake sites in the rat striatum. |
1992-08-24 |
2023-08-11 |
rat |
| J A Gorter, M H Botterblom, M G Feenstra, G J Boe. Chronic neonatal NMDA receptor blockade with MK-801 alters monoamine metabolism in the adult rat. Neuroscience letters. vol 137. issue 1. 1992-08-07. PMID:1320756. |
we examined the question whether chronic mk-801 treatment in neonatal rats from postnatal day 8 through 19, which has been shown previously to alter nmda receptor function, would also affect monoamine metabolism in striatum and frontal cortex of adult rats. |
1992-08-07 |
2023-08-11 |
rat |
| P S Whitton, C S Biggs, B R Pearce, L J Fowle. MK-801 increases extracellular 5-hydroxytryptamine in rat hippocampus and striatum in vivo. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1372346. |
mk-801 increases extracellular 5-hydroxytryptamine in rat hippocampus and striatum in vivo. |
1992-04-17 |
2023-08-11 |
rat |
| P S Whitton, C S Biggs, B R Pearce, L J Fowle. MK-801 increases extracellular 5-hydroxytryptamine in rat hippocampus and striatum in vivo. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1372346. |
the effect of mk-801 (0.25 or 0.5 mg/kg) on the extracellular concentration of 5-hydroxytryptamine (5-ht) and 5-hydroxyindoleacetic acid (5-hiaa) in rat hippocampus and striatum was studied using intracerebral dialysis. |
1992-04-17 |
2023-08-11 |
rat |
| P S Whitton, C S Biggs, B R Pearce, L J Fowle. MK-801 increases extracellular 5-hydroxytryptamine in rat hippocampus and striatum in vivo. Journal of neurochemistry. vol 58. issue 4. 1992-04-17. PMID:1372346. |
in contrast to this, the extracellular 5-hiaa content in the striatum was significantly decreased 150 min after administration of both doses of mk-801. |
1992-04-17 |
2023-08-11 |
rat |
| S Roussel, E Pinard, J Seyla. Effect of MK-801 on focal brain infarction in normotensive and hypertensive rats. Hypertension (Dallas, Tex. : 1979). vol 19. issue 1. 1992-02-14. PMID:1730437. |
mk-801 significantly reduced the neocortical volume of infarction (by about 32% at both doses) in fischer-344 rats and had no neuroprotective effects in the striatum. |
1992-02-14 |
2023-08-11 |
human |
| A Svensson, E Pileblad, M Carlsso. A comparison between the non-competitive NMDA antagonist dizocilpine (MK-801) and the competitive NMDA antagonist D-CPPene with regard to dopamine turnover and locomotor-stimulatory properties in mice. Journal of neural transmission. General section. vol 85. issue 2. 1991-12-17. PMID:1930876. |
following intraperitoneal administration of the non-competitive n-methyl-d-aspartate (nmda) antagonist dizocilpine (mk-801), levels of the dopamine (da) metabolites 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) increased in mouse striatum and limbic forebrain. |
1991-12-17 |
2023-08-11 |
mouse |
| W Löscher, R Annies, D Hönac. The N-methyl-D-aspartate receptor antagonist MK-801 induces increases in dopamine and serotonin metabolism in several brain regions of rats. Neuroscience letters. vol 128. issue 2. 1991-12-02. PMID:1834964. |
mk-801 increased dopamine and serotonin metabolism in several regions, the most marked effects being determined in frontal and piriform cortex, nucleus accumbens and striatum. |
1991-12-02 |
2023-08-11 |
rat |
| K Kashihara, K Okumura, M Onishi, S Otsuk. MK-801 fails to modify the effect of methamphetamine on dopamine release in the rat striatum. Neuroreport. vol 2. issue 5. 1991-11-14. PMID:1912453. |
mk-801 fails to modify the effect of methamphetamine on dopamine release in the rat striatum. |
1991-11-14 |
2023-08-11 |
rat |
| K Kashihara, K Okumura, M Onishi, S Otsuk. MK-801 fails to modify the effect of methamphetamine on dopamine release in the rat striatum. Neuroreport. vol 2. issue 5. 1991-11-14. PMID:1912453. |
these findings suggest that mk-801 fails to modify the acute effect of map on da release in the striatum. |
1991-11-14 |
2023-08-11 |
rat |
| C L Willis, C Brazell, A C Foste. Plasma and CSF levels of dizocilpine (MK-801) required for neuroprotection in the quinolinate-injected rat striatum. European journal of pharmacology. vol 196. issue 3. 1991-10-24. PMID:1832637. |
plasma and csf levels of dizocilpine (mk-801) required for neuroprotection in the quinolinate-injected rat striatum. |
1991-10-24 |
2023-08-11 |
rat |
| C L Willis, C Brazell, A C Foste. Plasma and CSF levels of dizocilpine (MK-801) required for neuroprotection in the quinolinate-injected rat striatum. European journal of pharmacology. vol 196. issue 3. 1991-10-24. PMID:1832637. |
this study has identified the range of plasma and cerebrospinal fluid (csf) concentrations of the uncompetitive n-methyl-d-aspartate receptor antagonist dizocilpine (mk-801) required for neuroprotection in the quinolinate-lesioned rat striatum. |
1991-10-24 |
2023-08-11 |
rat |
| K Gulya, K A Grant, P Valverius, P L Hoffman, B Tabakof. Brain regional specificity and time-course of changes in the NMDA receptor-ionophore complex during ethanol withdrawal. Brain research. vol 547. issue 1. 1991-09-05. PMID:1830510. |
the current studies, using quantitative autoradiography, demonstrate that chronic ethanol ingestion also produces increases in mk-801 binding in cerebral cortex, striatum and thalamus, as well as in hippocampus. |
1991-09-05 |
2023-08-11 |
mouse |
| S Liljequist, K Ossowska, M Grabowska-Andén, N E Andé. Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice. European journal of pharmacology. vol 195. issue 1. 1991-08-15. PMID:1829683. |
mk-801, 0.2 mg/kg i.p., a dose which produced marked locomotor stimulation, increased the rate of disappearance of dopamine in the striatum and in the limbic forebrain of the animals, whereas the rate of disappearance of noradrenaline remained unchanged in the limbic forebrain and in the hippocampus. |
1991-08-15 |
2023-08-11 |
mouse |
| S Liljequist, K Ossowska, M Grabowska-Andén, N E Andé. Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice. European journal of pharmacology. vol 195. issue 1. 1991-08-15. PMID:1829683. |
mk-801 increased the rate of tyrosine hydroxylation (measured as the accumulation of 3,4-dihydroxyphenylalanine (dopa) after inhibition of dopa decarboxylase) in the striatum with no change in dopa formation in the limbic forebrain. |
1991-08-15 |
2023-08-11 |
mouse |
| S Liljequist, K Ossowska, M Grabowska-Andén, N E Andé. Effect of the NMDA receptor antagonist, MK-801, on locomotor activity and on the metabolism of dopamine in various brain areas of mice. European journal of pharmacology. vol 195. issue 1. 1991-08-15. PMID:1829683. |
the levels of 3,4-dihydroxyphenylacetic acid (dopac) remained unchanged both in the striatum and in the limbic forebrain following the administration of mk-801. |
1991-08-15 |
2023-08-11 |
mouse |
| S Carboni, F Melis, A Vaccari, Z L Rossett. NMDA receptor activation mediates glutamate and aspartate release from rat striatum: prevention by MK-801. Pharmacological research. vol 22 Suppl 3. 1991-07-23. PMID:1982969. |
nmda receptor activation mediates glutamate and aspartate release from rat striatum: prevention by mk-801. |
1991-07-23 |
2023-08-11 |
rat |
| S Y Sakurai, J H Cha, J B Penney, A B Youn. Regional distribution and properties of [3H]MK-801 binding sites determined by quantitative autoradiography in rat brain. Neuroscience. vol 40. issue 2. 1991-06-12. PMID:2027471. |
[3h]mk-801 binding was heterogeneously distributed throughout the brain with the following order of binding densities: hippocampal formation greater than cortical areas greater than striatum greater than thalamus. |
1991-06-12 |
2023-08-11 |
rat |
| J E Steele, T N Robinson, A J Cross, D M Bowen, A R Gree. A comparison of [3H]MK-801 and N-[1-(2-thienyl)cyclohexyl]-3,4-[3H]piperidine binding to the N-methyl-D-aspartate receptor complex in human brain. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1672144. |
saturation analysis performed in the striatum revealed that the number of binding sites was the same for both [3h]mk-801 (bmax, 1,403 +/- 394 fmol/mg) and [3h]tcp (bmax, 1,292 +/- 305 fmol/mg). |
1991-04-15 |
2023-08-11 |
human |