| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Bustos, J Simon, R H Rot. Tyrosine hydroxylase regulation: apparent kinetic alterations following incubation of brain slices in a sodium-free medium. Journal of neurochemistry. vol 35. issue 1. 1981-03-17. PMID:6108991. |
furthermore, the activation of tyrosine hydroxylase produced by incubating slices in a na+-free medium is observed even in slices depleted of dopamine by pretreatment of rats with reserpine 90 min before preparation of brain slices. |
1981-03-17 |
2023-08-12 |
rat |
| T P Rothman, L A Specht, M D Gershon, T H Joh, G Teitelman, V M Pickel, D J Rei. Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 10. 1981-02-26. PMID:6108565. |
we sought to determine whether the precursors of catecholamine-containing neurons in the developing peripheral and central nervous systems of chickens and rats express the biosynthetic enzymes tyrosine hydroxylase [thase; tyrosine 3-monooxygenase; l-tyrosine, tetrahydropteridine: oxygen oxidoreductase (3-hydroxylating), ec 1.14.16.2] or dopamine beta-hydroxylase [dbhase; 3,4-dihydroxyphenylethylamine, ascorbate:oxygen oxidoreductase (beta-hydroxylating), ec 1.14.17.1], prior to the time they withdraw from the cell cycle. |
1981-02-26 |
2023-08-12 |
rat |
| B Scatton, B Zivkovic, J Dede. Antidopaminergic properties of yohimbine. The Journal of pharmacology and experimental therapeutics. vol 215. issue 2. 1981-02-26. PMID:7192314. |
increased in both striatum and limbic areas 1) homovanillic acid and dihydroxyphenylacetic acid levels, 2) tyrosine hydroxylase activity measured in vitro, 3) the in vivo accumulation of dihydroxyphenylalanine after nsd 1015 and 4) the rate of dopamine disappearance after alpha-methyl-p-tyrosine. |
1981-02-26 |
2023-08-12 |
rat |
| K Hisatomi, Y Niiyam. Effects of postnatal undernutrition on the catecholamine and serotonin contents of suckling rat brain. Journal of nutritional science and vitaminology. vol 26. issue 3. 1981-02-19. PMID:6160225. |
the tyrosine hydroxylase activity (pmol/g) correlated more closely with the norepinephrine content than with the dopamine or norepinephrine plus dopamine content. |
1981-02-19 |
2023-08-12 |
rat |
| H Bönisch, U Otten, H Thoene. The role of sodium influx mediated by nicotinic receptors as an initial event in trans-synaptic induction of tyrosine hydroxylase in adrenergic neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 313. issue 3. 1981-01-16. PMID:6107866. |
the effects of dopamine, chlorisondamine and tetrodotoxin on the carbachol-induced 22na uptake into superior cervical ganglia are similar to their effects on carbachol-mediated induction of tyrosine hydroxylase in superior cervical ganglia kept in tissue culture (thoenen and otten 1977b). |
1981-01-16 |
2023-08-12 |
rat |
| G W Kraemer, W T McKinne. Interactions of pharmacological agents which alter biogenic amine metabolism and depression--an analysis of contributing factors within a primate model of depression. Journal of affective disorders. vol 1. issue 1. 1980-12-18. PMID:45183. |
major emphasis will be placed on studies utilizing alpha-methyl-para-tyrosine, an inhibitor of tyrosine hydroxylase, to ostensively reduce levels of the catecholamine neurotransmitters norepinephrine and dopamine. |
1980-12-18 |
2023-08-11 |
human |
| W G Waggoner, J McDermed, H J Leighto. Presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs. Molecular pharmacology. vol 18. issue 1. 1980-11-25. PMID:6106156. |
presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs. |
1980-11-25 |
2023-08-12 |
rat |
| R H Alper, K T Demarest, K E Moor. Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems. Journal of neural transmission. vol 48. issue 3. 1980-10-27. PMID:6772740. |
on the basis of biochemical indices of dopamine (da) nerve activity (decline of da after inhibition of tyrosine hydroxylase, accumulation of dopa after inhibition of dopa decarboxylase) it was revealed that morphine increases the activity of nigrostriatal and mesolimbic da nerves which terminate in the striatum, nucleus accumbens and olfactory tubercle, but reduce the activity of tuberoinfundibular da nerves which terminate in the median eminence. |
1980-10-27 |
2023-08-12 |
rat |
| J F Flood, G E Smith, M E Jarvi. A comparison of the effects of localized brain administration of catecholamine and protein synthesis inhibitors on memory processing. Brain research. vol 197. issue 1. 1980-10-24. PMID:6249456. |
tyrosine hydroxylase is needed for the conversion of tyrosine to dopamine (da) and norpinephrine (ne); altering the level of this enzyme could affect catecholamine (ca) turnover. |
1980-10-24 |
2023-08-12 |
Not clear |
| F Hefti, E Melamed, R J Wurtma. Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization. Brain research. vol 195. issue 1. 1980-10-21. PMID:6105003. |
the resulting reduction in striatal dopamine concentrations and tyrosine hydroxylase activities tended to be proportional, allowing these measurements to serve as indices for lesion severity in any particular animal. |
1980-10-21 |
2023-08-12 |
rat |
| G Jahnke, G Nicholson, G H Greeley, W W Youngblood, A J Prange, J S Kize. Studies of the neural mechanisms by which hypothyroidism decreases prolactin secretion in the rat. Brain research. vol 191. issue 2. 1980-08-15. PMID:6103734. |
an investigation of those mechanisms by which hypothyroidism decreases prolactin secretion revealed the following findings: (1) activation of tyrosine hydroxylase in the median eminence (me) and increase in the turnover-rate of dopamine (da) in the me; (2) a decreased content and in vitro release of prolactin by pituitaries from hypothyroid rats; (3) decreased [3h]spiroperidol binding to pituitary homogenates obtained from hypothyroid rats, and (4) normal increase of serum prolactin following administration of haloperidol. |
1980-08-15 |
2023-08-12 |
rat |
| G Nicholson, G H Greeley, J Humm, W W Youngblood, J S Kize. Prolactin in cerebrospinal fluid: a probable site of prolactin autoregulation. Brain research. vol 190. issue 2. 1980-07-28. PMID:6102886. |
in the median eminence, but not the medial preoptic area, parallel increases in the activity of tyrosine hydroxylase and the turnover of dopamine (but not norepinephrine) occurred following hyperprolactinemia. |
1980-07-28 |
2023-08-12 |
rat |
| F Boismare, M Le Poncin-Lafitte, J R Rapi. Blockade of the different enzymatic steps in the synthesis of brain amines and memory (CAR) in hypobaric hypoxic rats treated and untreated with L. dopa. Aviation, space, and environmental medicine. vol 51. issue 2. 1980-05-30. PMID:7362556. |
l. dopa loses its protective effect against hypoxia if tyrosine hydroxylase, dopadecarboxylase, or dopamine beta hydroxylase is previously blocked. |
1980-05-30 |
2023-08-12 |
rat |
| S M Sagar, S R Snodgras. Effects of substantia nigra lesions on forebrain 2-deoxyglucose retention in the rat. Brain research. vol 185. issue 2. 1980-05-14. PMID:6101986. |
the location and efficacy of the lesions were verified histologically, behaviorally (by observing rotational behavior), and biochemically (by assay of striatal dopamine concentration or tyrosine hydroxylase activity). |
1980-05-14 |
2023-08-12 |
rat |
| G M Gilad, D J Rei. Failure to detect collateral sprouting of mesolimbic dopaminergic neurons during early postnatal development. Brain research. vol 186. issue 1. 1980-05-14. PMID:6101989. |
on the other hand, tyrosine hydroxylase (th) and [3h]dopamine ([3h]da) uptake, while present at low levels, start to increase rapidly only after the first 7 days reaching adult levels by 40 and 20 days after birth, respectively. |
1980-05-14 |
2023-08-12 |
rat |
| M Y Mcginnis, J H Gordon, R A Gorsk. Influence of gamma-aminobutyric acid on lordosis behavior and dopamine activity in estrogen primed spayed female rats. Brain research. vol 184. issue 1. 1980-05-14. PMID:7357416. |
tyrosine hydroxylase (th) activity and dopamine (da) and homovanillic acid (hva) levels were measured. |
1980-05-14 |
2023-08-12 |
rat |
| J W Gibb, F J Koga. Influence of dopamine synthesis on methamphetamine-induced changes in striatal and adrenal tyrosine hydroxylase activity. Naunyn-Schmiedeberg's archives of pharmacology. vol 310. issue 2. 1980-04-26. PMID:43481. |
influence of dopamine synthesis on methamphetamine-induced changes in striatal and adrenal tyrosine hydroxylase activity. |
1980-04-26 |
2023-08-11 |
Not clear |
| A Purdy, A Hahn, H J Barnett, P Bratty, D Ahmad, K G Lloyd, E G McGeer, T L Perr. Familial fatal Parkinsonism with alveolar hypoventilation and mental depression. Annals of neurology. vol 6. issue 6. 1980-04-26. PMID:43704. |
degeneration of the nigrostriatal dopaminergic system is evidenced by low levels of tyrosine hydroxylase, dopamine, homovanillic acid, and l-dopa decarboxylase in postmortem brain samples. |
1980-04-26 |
2023-08-11 |
Not clear |
| J L Tyler, J H Gordon, R A Gorsk. Effects of olfactory bulbectomy and estrogen on tyrosine hydroxylase and glutamic acid decarboxylase in the nigrostriatal and mesolimbic dopamine systems of adult female rats. Pharmacology, biochemistry, and behavior. vol 11. issue 5. 1980-04-25. PMID:43516. |
effects of olfactory bulbectomy and estrogen on tyrosine hydroxylase and glutamic acid decarboxylase in the nigrostriatal and mesolimbic dopamine systems of adult female rats. |
1980-04-25 |
2023-08-11 |
rat |
| P M Beart, D McDonald, A L Gundlac. Mesolimbic dopaminergic neurones and somatodendritic mechanisms. Neuroscience letters. vol 15. issue 2-3. 1980-04-23. PMID:43496. |
the rat ventral tegmentum (containing dendrites and somata of mesolimbic dopaminergic neurones) possessed high levels of dopamine and tyrosine hydroxylase. |
1980-04-23 |
2023-08-11 |
rat |