| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| W W Morgan, K A Pfei. Evidence for a cholinergic influence on catecholaminergic pathways terminating in the anterior and medial basal hypothalamus. Brain research. vol 173. issue 1. 1979-12-20. PMID:487084. |
adult male sprague-dawley rats were given hourly injections of physostigmine for 1--4 h, and the effect of this treatment on dopamine (da) and noradrenaline (na) content or on da and na was estimated by measuring the decline in these amines produced following the inhibition of tyrosine hydroxylase with alpha-methyl-p-tyrosine (alpha mpt). |
1979-12-20 |
2023-08-11 |
rat |
| T Hattori, P L McGeer, E G McGee. Dendro axonic neurotransmission. II. Morphological sites for the synthesis, binding and release of neurotransmitters in dopaminergic dendrites in the substantia nigra and cholinergic dendrites in the neostriatum. Brain research. vol 170. issue 1. 1979-10-17. PMID:37984. |
the dopamine synthesizing enzyme, tyrosine hydroxylase (th), is localized to microtubules and smooth endoplasmic reticulum which approach the postsynaptic membrane. |
1979-10-17 |
2023-08-11 |
cat |
| J H Gordon, D M Nance, C J Wallis, R A Gorsk. Effects of septal lesions and chronic estrogen treatment on dopamine, GABA and lordosis behavior in male rats. Brain research bulletin. vol 4. issue 1. 1979-10-17. PMID:37995. |
tyrosine hydroxylase (th) activity was assayed in the dopamine (da) rich areas of the forebrain (striatum, str, nucleus accumbens septi, acb; and olfactory tubercle). |
1979-10-17 |
2023-08-11 |
rat |
| S P Tyrer, H T Delves, M P Welle. CSF copper in schizophrenia. The American journal of psychiatry. vol 136. issue 7. 1979-09-01. PMID:453356. |
these enzymes, tyrosine hydroxylase and dopamine-beta-hydroxylase, are involved in the synthesis and catabolism of dopamine. |
1979-09-01 |
2023-08-11 |
human |
| J C Cheronis, L Erinoff, A Heller, P C Hoffman. Pharmacological analysis of the functional ontogeny of the nigrostriatal dopaminergic neurons. Brain research. vol 169. issue 3. 1979-08-16. PMID:36209. |
this axotomy-induced increase in striatal dopamine is believed to be a response of the dopaminergic terminals to cessation of impulse traffic and is secondary to a decrease in dopamine release and a concomitant increase in dopamine synthesis resulting from tyrosine hydroxylase activation. |
1979-08-16 |
2023-08-11 |
rat |
| G Kapatos, M J Zigmon. Effect of haloperidol on dopamine synthesis and tyrosine hydroxylase in striatal synaptosomes. The Journal of pharmacology and experimental therapeutics. vol 208. issue 3. 1979-06-29. PMID:34711. |
effect of haloperidol on dopamine synthesis and tyrosine hydroxylase in striatal synaptosomes. |
1979-06-29 |
2023-08-11 |
Not clear |
| R H Schmidt, R K Bhatnaga. Assessment of the effects of neonatal subcutaneous 6-hydroxydopamine on noradrenergic and dopaminergic innervation of the cerebral cortex. Brain research. vol 166. issue 2. 1979-06-26. PMID:34469. |
two weeks later regions of the telencephalon, both ipsi- and contralateral to the lesion, were simultaneously assayed for norepinephrine (ne) and dopamine (da) content, and for tyrosine hydroxylase (toh) and dopamine-beta-hydroxylase (dbh) activities. |
1979-06-26 |
2023-08-11 |
rat |
| J C Waymire, K Gilmer-Waymire, D Noritake, G Gibson, D Kitayama, J W Haycoc. Induction of tyrosine hydroxylase and dopamine beta-hydroxylase in cultured mouse neuroblastoma by 8Br-cAMP. Involvement of RNA and protein synthesis. Molecular pharmacology. vol 15. issue 1. 1979-05-23. PMID:34092. |
induction of tyrosine hydroxylase and dopamine beta-hydroxylase in cultured mouse neuroblastoma by 8br-camp. |
1979-05-23 |
2023-08-11 |
mouse |
| J B Furness, M Costa, C G Freema. Absence of tyrosine hydroxylase activity and dopamine beta-hydroxylase immunoreactivity in intrinsic nerves of the guinea-pig ileum. Neuroscience. vol 4. issue 2. 1979-05-16. PMID:34125. |
absence of tyrosine hydroxylase activity and dopamine beta-hydroxylase immunoreactivity in intrinsic nerves of the guinea-pig ileum. |
1979-05-16 |
2023-08-11 |
Not clear |
| V Dequattro, I Eide, M R Myers, K Eide, R Kolloch, H Whigha. Enhanced hypothalamic noradrenaline biosynthesis in Goldblatt I renovascular hypertension. Clinical science and molecular medicine. Supplement. vol 4. 1979-03-24. PMID:32000. |
hypothalamic tyrosine hydroxylase and dopamine beta-hydroxylase activities, and the concentration of noradrenaline were increased in the goldblatt i animals after 3 weeks. |
1979-03-24 |
2023-08-11 |
rat |
| G M Gilad, D J Rei. Collateral sprouting in central mesolimbic dopamine neurons: biochemical and immunocytochemical evidence of changes in the activity and distrubution of tyrosine hydroxylase in terminal fields and in cell bodies of A10 neurons. Brain research. vol 160. issue 1. 1979-02-21. PMID:31232. |
collateral sprouting in central mesolimbic dopamine neurons: biochemical and immunocytochemical evidence of changes in the activity and distrubution of tyrosine hydroxylase in terminal fields and in cell bodies of a10 neurons. |
1979-02-21 |
2023-08-11 |
rat |
| E D Bird, L L Iverse. Neurochemical findings in Huntington's chorea. Essays in neurochemistry and neuropharmacology. vol 1. 1979-01-26. PMID:152197. |
most studies have found the dopamine concentrations to be normal or sometimes decreased and the activity of the biosynthetic enzyme for dopamine, tyrosine hydroxylase, is normal. |
1979-01-26 |
2023-08-11 |
Not clear |
| P M Iuvone, C L Galli, C K Garrison-Gund, N H Nef. Light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons. Science (New York, N.Y.). vol 202. issue 4370. 1979-01-15. PMID:30997. |
light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons. |
1979-01-15 |
2023-08-11 |
rat |
| P M Iuvone, C L Galli, C K Garrison-Gund, N H Nef. Light stimulates tyrosine hydroxylase activity and dopamine synthesis in retinal amacrine neurons. Science (New York, N.Y.). vol 202. issue 4370. 1979-01-15. PMID:30997. |
retinal dopamine-containing amacrine neurons are rapidly activated by light, as shown by an increase in the rate of dopamine formation in vivo and a concomitant increase in the activity of tyrosine hydroxylase, measured in vitro with a subsaturating concentration of pteridine cofactor. |
1979-01-15 |
2023-08-11 |
rat |
| G Di Chiara, P L Onali, A H Tissari, M L Porceddu, M Morelli, G L Gess. Destruction of post-synaptic dopamine receptors prevents neuroleptic-induced activation of striatal tyrosine hydroxylase but not dopamine synthesis stimulation. Life sciences. vol 23. issue 7. 1978-12-02. PMID:29204. |
destruction of post-synaptic dopamine receptors prevents neuroleptic-induced activation of striatal tyrosine hydroxylase but not dopamine synthesis stimulation. |
1978-12-02 |
2023-08-11 |
Not clear |
| G R Van Loon, M J Sole, A Kamble, C Kim, S Gree. Differential responsiveness of central noradrenergic and dopaminergic neuron tyrosine hydroxylase to hypophysectomy, ACTH and glucocorticoid administration. Annals of the New York Academy of Sciences. vol 297. 1978-12-02. PMID:29550. |
hypophysectomy leads to a small increase in tyrosine hydroxylase activity of all brain areas containing noradrenergic neurons or tuberoinfundibular dopamine neurons, but nigroneostriatal dopamine neurons are not so affected. |
1978-12-02 |
2023-08-11 |
Not clear |
| G R Van Loon, M J Sole, A Kamble, C Kim, S Gree. Differential responsiveness of central noradrenergic and dopaminergic neuron tyrosine hydroxylase to hypophysectomy, ACTH and glucocorticoid administration. Annals of the New York Academy of Sciences. vol 297. 1978-12-02. PMID:29550. |
the disparity between increased hypothalamic tyrosine hydroxylase activity and decreased norepinephrine turnover following hypophysectomy may result from a change in the rate-limiting step to the hydroxylation of dopamine. |
1978-12-02 |
2023-08-11 |
Not clear |
| J C Waymire, K Gilmer-Waymire, R E Boehm. Concomitant elevation of tyrosine hydroxylase and dopamine beta-hydroxylase by cyclic AMP in cultured mouse neuroblastoma cells. Journal of neurochemistry. vol 31. issue 3. 1978-10-18. PMID:28385. |
concomitant elevation of tyrosine hydroxylase and dopamine beta-hydroxylase by cyclic amp in cultured mouse neuroblastoma cells. |
1978-10-18 |
2023-08-11 |
mouse |
| T Lloyd, J Weis. Direct inhibition of tyrosine hydroxylase activity by catechol estrogens. The Journal of biological chemistry. vol 253. issue 14. 1978-09-15. PMID:27508. |
catechol estrogens, the 2-hydroxylated metabolites of estrogens, recently shown to be formed in brain, inhibit tyrosine hydroxylase, the enzyme that catalyzes the pivotal step in the biosynthesis of the neurotransmitters dopamine and norepinephrine. |
1978-09-15 |
2023-08-11 |
Not clear |
| G Ellison, M S Eison, H S Huberman, F Danie. Long-term changes in dopaminergic innervation of caudate nucleus after continuous amphetamine administration. Science (New York, N.Y.). vol 201. issue 4352. 1978-08-28. PMID:26975. |
several days after implantation, swollen dopamine axons concomitant with large decreases in tyrosine hydroxylase activity were observed in the caudate nucleus. |
1978-08-28 |
2023-08-11 |
rat |