| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P M Iuvone, N H Nef. Dopamine neurons of the retina: a simple method system for studying synaptic regulatory mechanisms. Essays in neurochemistry and neuropharmacology. vol 5. 1981-07-20. PMID:7014214. |
short term exposure to light increases dopamine turnover and activates tyrosine hydroxylase, which is characterized by a decrease in the km of the enzyme for the pteridine cofactor. |
1981-07-20 |
2023-08-12 |
rat |
| T Tsudzuk. Studies on the uptake of [3H]dopamine by synaptic vesicle fraction isolated from bovine brain. Journal of biochemistry. vol 89. issue 1. 1981-06-13. PMID:6111561. |
a synaptic vesicle fraction isolated from bovine caudatolenticular nuclei showed enzymic activities of tyrosine hydroxylase [ec 1.14.16.2] and dopamine beta-hydroxylase [ec 1.14.17.1]. |
1981-06-13 |
2023-08-12 |
cattle |
| K T Demarest, D W McKay, G D Riegle, K E Moor. Sexual differences in tuberoinfundibular dopamine nerve activity induced by neonatal androgen exposure. Neuroendocrinology. vol 32. issue 2. 1981-05-28. PMID:6782499. |
the activities of different catecholaminergic neurons in the brains of male amd female rats were estimated by measuring (1) the rate of decline of dopamine (da) and norepinephrine (ne) after inhibition of tyrosine hydroxylase with alpha-methyltyrosine (alpha-mt) and (2) the rate of accumulation of dihydroxyphenylalanine (dopa) after inhibition of dopa decarboxylase with nsd 1015 in brain regions containing the terminals of these neurons. |
1981-05-28 |
2023-08-12 |
rat |
| D C German, B A McMillen, M K Sanghera, S I Saffer, P A Shor. Effects of severe dopamine depletion on dopamine neuronal impulse flow and on tyrosine hydroxylase regulation. Brain research bulletin. vol 6. issue 2. 1981-05-26. PMID:6110470. |
effects of severe dopamine depletion on dopamine neuronal impulse flow and on tyrosine hydroxylase regulation. |
1981-05-26 |
2023-08-12 |
rat |
| D C German, B A McMillen, M K Sanghera, S I Saffer, P A Shor. Effects of severe dopamine depletion on dopamine neuronal impulse flow and on tyrosine hydroxylase regulation. Brain research bulletin. vol 6. issue 2. 1981-05-26. PMID:6110470. |
reserpine depletes dopamine (da) levels and increases tyrosine hydroxylase (th) activity in the rat corpus striatum. |
1981-05-26 |
2023-08-12 |
rat |
| F Cerrito, M Raiter. Dopamine biosynthesis is regulated by the amine newly recaptured by dopaminergic nerve endings. European journal of pharmacology. vol 68. issue 4. 1981-05-26. PMID:7202503. |
in the present paper it is proposed that the regulation of dopamine synthesis occurs through inhibition of tyrosine hydroxylase, according to the classical and end-product concept; however, the function of 'end-product' would be primarily exerted by the amine newly taken up by the nerve terminals. |
1981-05-26 |
2023-08-12 |
rat |
| F Hefti, E Melamed, R J Wurtma. The site of dopamine formation in rat striatum after L-dopa administration. The Journal of pharmacology and experimental therapeutics. vol 217. issue 1. 1981-05-26. PMID:7205652. |
unilateral nigrostriatal lesions produced by injecting 6-hydroxydopamine stereotaxically into both the substantia nigra and the medial forebrain bundle reduced striatal tyrosine hydroxylase activity and dopamine (da) concentrations by 95% (compared with the intact, contralateral striata) but lowered dopa decarboxylase (ddc) activity by only 80%. |
1981-05-26 |
2023-08-12 |
rat |
| B A McMillen, P A Shor. Role of dopamine storage function in the control of rat striatal tyrosine hydroxylase activity. Naunyn-Schmiedeberg's archives of pharmacology. vol 313. issue 1. 1981-05-21. PMID:6111026. |
role of dopamine storage function in the control of rat striatal tyrosine hydroxylase activity. |
1981-05-21 |
2023-08-12 |
rat |
| R Kuczensk. Amphetamine-haloperidol interactions on striatal and mesolimbic tyrosine hydroxylase activity and dopamine metabolism. The Journal of pharmacology and experimental therapeutics. vol 215. issue 1. 1981-03-27. PMID:6109012. |
amphetamine-haloperidol interactions on striatal and mesolimbic tyrosine hydroxylase activity and dopamine metabolism. |
1981-03-27 |
2023-08-12 |
rat |
| R Kuczensk. Amphetamine-haloperidol interactions on striatal and mesolimbic tyrosine hydroxylase activity and dopamine metabolism. The Journal of pharmacology and experimental therapeutics. vol 215. issue 1. 1981-03-27. PMID:6109012. |
rat striatal and mesolimbic dopamine (da), 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid levels and the activity of tyrosine hydroxylase (toh) were determined as a function of dose of amphetamine (amph) or haloperidol (hal). |
1981-03-27 |
2023-08-12 |
rat |
| G Bustos, J Simon, R H Rot. Tyrosine hydroxylase regulation: apparent kinetic alterations following incubation of brain slices in a sodium-free medium. Journal of neurochemistry. vol 35. issue 1. 1981-03-17. PMID:6108991. |
furthermore, the activation of tyrosine hydroxylase produced by incubating slices in a na+-free medium is observed even in slices depleted of dopamine by pretreatment of rats with reserpine 90 min before preparation of brain slices. |
1981-03-17 |
2023-08-12 |
rat |
| T P Rothman, L A Specht, M D Gershon, T H Joh, G Teitelman, V M Pickel, D J Rei. Catecholamine biosynthetic enzymes are expressed in replicating cells of the peripheral but not the central nervous system. Proceedings of the National Academy of Sciences of the United States of America. vol 77. issue 10. 1981-02-26. PMID:6108565. |
we sought to determine whether the precursors of catecholamine-containing neurons in the developing peripheral and central nervous systems of chickens and rats express the biosynthetic enzymes tyrosine hydroxylase [thase; tyrosine 3-monooxygenase; l-tyrosine, tetrahydropteridine: oxygen oxidoreductase (3-hydroxylating), ec 1.14.16.2] or dopamine beta-hydroxylase [dbhase; 3,4-dihydroxyphenylethylamine, ascorbate:oxygen oxidoreductase (beta-hydroxylating), ec 1.14.17.1], prior to the time they withdraw from the cell cycle. |
1981-02-26 |
2023-08-12 |
rat |
| B Scatton, B Zivkovic, J Dede. Antidopaminergic properties of yohimbine. The Journal of pharmacology and experimental therapeutics. vol 215. issue 2. 1981-02-26. PMID:7192314. |
increased in both striatum and limbic areas 1) homovanillic acid and dihydroxyphenylacetic acid levels, 2) tyrosine hydroxylase activity measured in vitro, 3) the in vivo accumulation of dihydroxyphenylalanine after nsd 1015 and 4) the rate of dopamine disappearance after alpha-methyl-p-tyrosine. |
1981-02-26 |
2023-08-12 |
rat |
| K Hisatomi, Y Niiyam. Effects of postnatal undernutrition on the catecholamine and serotonin contents of suckling rat brain. Journal of nutritional science and vitaminology. vol 26. issue 3. 1981-02-19. PMID:6160225. |
the tyrosine hydroxylase activity (pmol/g) correlated more closely with the norepinephrine content than with the dopamine or norepinephrine plus dopamine content. |
1981-02-19 |
2023-08-12 |
rat |
| H Bönisch, U Otten, H Thoene. The role of sodium influx mediated by nicotinic receptors as an initial event in trans-synaptic induction of tyrosine hydroxylase in adrenergic neurons. Naunyn-Schmiedeberg's archives of pharmacology. vol 313. issue 3. 1981-01-16. PMID:6107866. |
the effects of dopamine, chlorisondamine and tetrodotoxin on the carbachol-induced 22na uptake into superior cervical ganglia are similar to their effects on carbachol-mediated induction of tyrosine hydroxylase in superior cervical ganglia kept in tissue culture (thoenen and otten 1977b). |
1981-01-16 |
2023-08-12 |
rat |
| G W Kraemer, W T McKinne. Interactions of pharmacological agents which alter biogenic amine metabolism and depression--an analysis of contributing factors within a primate model of depression. Journal of affective disorders. vol 1. issue 1. 1980-12-18. PMID:45183. |
major emphasis will be placed on studies utilizing alpha-methyl-para-tyrosine, an inhibitor of tyrosine hydroxylase, to ostensively reduce levels of the catecholamine neurotransmitters norepinephrine and dopamine. |
1980-12-18 |
2023-08-11 |
human |
| W G Waggoner, J McDermed, H J Leighto. Presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs. Molecular pharmacology. vol 18. issue 1. 1980-11-25. PMID:6106156. |
presynaptic regulation of tyrosine hydroxylase activity in rat striatal synaptosomes by dopamine analogs. |
1980-11-25 |
2023-08-12 |
rat |
| R H Alper, K T Demarest, K E Moor. Morphine differentially alters synthesis and turnover of dopamine in central neuronal systems. Journal of neural transmission. vol 48. issue 3. 1980-10-27. PMID:6772740. |
on the basis of biochemical indices of dopamine (da) nerve activity (decline of da after inhibition of tyrosine hydroxylase, accumulation of dopa after inhibition of dopa decarboxylase) it was revealed that morphine increases the activity of nigrostriatal and mesolimbic da nerves which terminate in the striatum, nucleus accumbens and olfactory tubercle, but reduce the activity of tuberoinfundibular da nerves which terminate in the median eminence. |
1980-10-27 |
2023-08-12 |
rat |
| J F Flood, G E Smith, M E Jarvi. A comparison of the effects of localized brain administration of catecholamine and protein synthesis inhibitors on memory processing. Brain research. vol 197. issue 1. 1980-10-24. PMID:6249456. |
tyrosine hydroxylase is needed for the conversion of tyrosine to dopamine (da) and norpinephrine (ne); altering the level of this enzyme could affect catecholamine (ca) turnover. |
1980-10-24 |
2023-08-12 |
Not clear |
| F Hefti, E Melamed, R J Wurtma. Partial lesions of the dopaminergic nigrostriatal system in rat brain: biochemical characterization. Brain research. vol 195. issue 1. 1980-10-21. PMID:6105003. |
the resulting reduction in striatal dopamine concentrations and tyrosine hydroxylase activities tended to be proportional, allowing these measurements to serve as indices for lesion severity in any particular animal. |
1980-10-21 |
2023-08-12 |
rat |