| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| T R Stratford, D Wirtshafte. Ascending dopaminergic projections from the dorsal raphe nucleus in the rat. Brain research. vol 511. issue 1. 1990-06-04. PMID:1970510. |
the projections of putative dopamine containing cells within the dorsal raphe nucleus (dr) were studied using a combination of tyrosine hydroxylase (th) immunocytochemistry and fluorescent retrograde tracing. |
1990-06-04 |
2023-08-11 |
rat |
| E E Jones, F Naftoli. Estrogen effects on the tuberoinfundibular dopaminergic system in the female rat brain. Brain research. vol 510. issue 1. 1990-05-21. PMID:1969760. |
estrogen effects on tyrosine hydroxylase (th), monoamine oxidase types a and b (mao), and dopamine (da) in microdissected regions of the hypothalamus, preoptic area and substantia nigra (snr) of the female rat brain were investigated. |
1990-05-21 |
2023-08-11 |
rat |
| T Nagats. [The search for endogenous or exogenous MPTP-like substances]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2517047. |
like mptp, tiq inhibits tyrosine hydroxylase and nadph ubiquinone oxidoreductase to reduce dopamine and atp in the nigrostriatal dopaminergic neurons. |
1990-05-04 |
2023-08-11 |
human |
| M Yoshid. [Tetrahydroisoquinoline and parkinsonism]. Rinsho shinkeigaku = Clinical neurology. vol 29. issue 12. 1990-05-04. PMID:2630145. |
dopamine, total biopterine and tyrosine hydroxylase (th) were decreased in the substantia nigra of tiq treated monkeys compared to saline treated monkeys (n = 5). |
1990-05-04 |
2023-08-11 |
mouse |
| W J Smeets, H W Steinbusc. New insights into the reptilian catecholaminergic systems as revealed by antibodies against the neurotransmitters and their synthetic enzymes. Journal of chemical neuroanatomy. vol 3. issue 1. 1990-05-02. PMID:1969276. |
the catecholaminergic systems in the lizard gekko gecko and the turtle pseudemys scripta elegans have been studied with specific and sensitive antibodies against the neurotransmitters dopamine (da) and noradrenaline (na) and the biosynthetic enzymes tyrosine hydroxylase (th), dopamine-beta-hydroxylase (dbh) and phenylethanolamine-n-methyltransferase. |
1990-05-02 |
2023-08-11 |
Not clear |
| M Hagihara, A Togari, S Matsumoto, T Nagats. Dietary calcium deprivation increased the levels of plasma catecholamines and catecholamine-synthesizing enzymes of adrenal glands in rats. Biochemical pharmacology. vol 39. issue 7. 1990-04-30. PMID:1969734. |
adrenal gland catecholamines were decreased while tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) were found to be increased, as compared to controls. |
1990-04-30 |
2023-08-11 |
rat |
| E Sas, L Maler, B Tinne. Catecholaminergic systems in the brain of a gymnotiform teleost fish: an immunohistochemical study. The Journal of comparative neurology. vol 292. issue 1. 1990-04-25. PMID:1968915. |
the localization of catecholamines (ca) in the brain of apteronotus leptorhynchus was studied with immunohistochemical techniques using antibodies to the enzymes tyrosine hydroxylase (th), dopamine b-hydroxylase (dbh), phenylethanolamine-n-methyltransferase (pnmt), and the neurotransmitter dopamine (da). |
1990-04-25 |
2023-08-11 |
Not clear |
| K Koshimura, S Miwa, K Lee, M Fujiwara, Y Watanab. Enhancement of dopamine release in vivo from the rat striatum by dialytic perfusion of 6R-L-erythro-5,6,7,8-tetrahydrobiopterin. Journal of neurochemistry. vol 54. issue 4. 1990-04-20. PMID:1968962. |
we have previously reported that intracerebroventricular administration of 6r-l-erythro-5,6,7,8-tetrahydrobiopterin (6r-bh4), a cofactor for tyrosine hydroxylase, enhances biosynthesis of 3,4-dihydroxyphenylethylamine (dopamine) in the rat brain. |
1990-04-20 |
2023-08-11 |
rat |
| H Baker, C A Gree. Region-specific consequences of PCD gene expression in the olfactory system. The Journal of comparative neurology. vol 293. issue 1. 1990-04-16. PMID:1968917. |
previous studies in normal mice, with tyrosine hydroxylase (th) enzyme as a marker, demonstrated that following peripheral olfactory afferent denervation the juxtaglomerular dopamine neurons exhibited a large reduction in th activity and immunoreactivity. |
1990-04-16 |
2023-08-11 |
mouse |
| M Pintor, I N Mefford, I Hutter, S L Pocotte, A R Wyler, N S Nad. Levels of biogenic amines, their metabolites, and tyrosine hydroxylase activity in the human epileptic temporal cortex. Synapse (New York, N.Y.). vol 5. issue 2. 1990-04-09. PMID:1968684. |
the levels of serotonin (5-ht), 5 hydroxyindoleacetic acid (5-hiaa), dopamine (da), homovanillic acid (hva), norepinephrine (ne), and tyrosine hydroxylase (th) activity were measured in the focus (spiking) and nonfocus (nonspiking) regions of the temporal neocortex of 20 patients with intractable complex partial seizures. |
1990-04-09 |
2023-08-11 |
human |
| R J Robbins, I Torres-Aleman, C Lebranth, C W Bradberry, A Y Deutch, S Welsh, R H Roth, D Spencer, D E Redmond, F Naftoli. Cryopreservation of human brain tissue. Experimental neurology. vol 107. issue 3. 1990-04-05. PMID:1968397. |
thawed brain fragments retained high viability after storage in liquid nitrogen and when grown in vitro exhibited neuronal morphology, tyrosine hydroxylase immunoreactivity, and dopamine production. |
1990-04-05 |
2023-08-11 |
human |
| P J Hornby, D T Pieku. Opiocortin and catecholamine input to CRF-immunoreactive neurons in rat forebrain. Peptides. vol 10. issue 6. 1990-03-19. PMID:2622800. |
antibodies to crf, acth(1-39) and the catecholamine synthesizing enzymes which are tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh) and phenylethanolamine-n-methyltransferase (pnmt) were utilized. |
1990-03-19 |
2023-08-11 |
rat |
| W Birkmayer, G J Birkmaye. Strategy and tactic of modern Parkinson therapy. Acta neurologica Scandinavica. Supplementum. vol 126. 1990-03-05. PMID:2694735. |
this can be achieved in two ways: (a) substitution of the lacking dopamine by l-dopa, or (b) stimulation of the endogenous biosynthesis by activating the enzyme tyrosine hydroxylase. |
1990-03-05 |
2023-08-11 |
Not clear |
| M el-Azouzi, D W Hsu, P M Black, F Jolesz, E T Hedley-Whyte, A Klibanski, N T Zerva. The importance of dopamine in the pathogenesis of experimental prolactinomas. Journal of neurosurgery. vol 72. issue 2. 1990-02-21. PMID:1967303. |
immunocytochemical staining for tyrosine hydroxylase was used as a marker for dopamine synthesis, plasma radioimmunoassay provided plasma prolactin levels, and magnetic resonance imaging and histological studies were performed to examine the structural changes occurring in the pituitary gland. |
1990-02-21 |
2023-08-11 |
rat |
| H T Chang, H Ku. Adrenergic innervation of the substantia innominata: co-localization of phenylethanolamine N-methyltransferase and tyrosine hydroxylase immunoreactivities within the same axons. Brain research. vol 503. issue 2. 1990-02-12. PMID:2575009. |
using primary antibodies derived from different species, we demonstrated in double-immunofluorescence labeling experiments that all pnmt-immunoreactive fibers in si are also immunoreactive for tyrosine hydroxylase, the synthetic enzyme for dopamine. |
1990-02-12 |
2023-08-11 |
rat |
| J Engele, C Pilgrim, I Reiser. Sexual differentiation of mesencephalic neurons in vitro: effects of sex and gonadal hormones. International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience. vol 7. issue 6. 1990-02-06. PMID:2603757. |
it was ascertained by use of specific inhibitors and by autoradiography that the uptake of [3h]dopamine was restricted to neurons immunoreactive for tyrosine hydroxylase and that these neurons have dopaminergic properties. |
1990-02-06 |
2023-08-11 |
rat |
| I Date, S Y Felten, D L Felte. Exogenous GM1 gangliosides induce partial recovery of the nigrostriatal dopaminergic system in MPTP-treated young mice but not in aging mice. Neuroscience letters. vol 106. issue 3. 1990-01-26. PMID:2601883. |
the administration of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to young (2-3 months) and aging (12 months) c57bl/6 mice (4 x 20 mg/kg, i.p., given 12 h apart) reduced tyrosine hydroxylase (th)-immunoreactive (ir) fibers in the striatum, and reduced dopamine (da) concentration to 28% of controls in young, and 16% of controls in aging mouse brain five weeks after administration. |
1990-01-26 |
2023-08-11 |
mouse |
| D M Yurek, A Y Deutch, R H Roth, J R Slade. Morphological, neurochemical, and behavioral characterizations associated with the combined treatment of diethyldithiocarbamate and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine in mice. Brain research. vol 497. issue 2. 1990-01-11. PMID:2573405. |
changes in striatal dopamine (da) neurochemistry, tyrosine hydroxylase immunocytochemistry of da fibers, and behavior following the combined administration of diethyldithiocarbamate (ddc) and 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (mptp) to mice were assessed. |
1990-01-11 |
2023-08-11 |
mouse |
| S B Dunnett, D J Sirinathsinghji, R Heavens, D C Rogers, M R Kueh. Monoamine deficiency in a transgenic (Hprt-) mouse model of Lesch-Nyhan syndrome. Brain research. vol 501. issue 2. 1990-01-08. PMID:2573408. |
by contrast, the mutant mice manifested normal tyrosine hydroxylase immunostaining of catecholamine cell bodies and terminals throughout the forebrain, and cell counts revealed no detectable loss of ventral mesencephalic dopamine neurones. |
1990-01-08 |
2023-08-11 |
mouse |
| O Magnusson, C J Fowle. Comparison of the effects of the novel antipsychotic agent remoxipride on dopamine and noradrenaline turnover in the rat brain. Pharmacology & toxicology. vol 65. issue 4. 1990-01-08. PMID:2573899. |
both remoxipride (5.6 mumol/kg intraperitoneally) and haloperidol (0.23 mumol/kg intraperitoneally) increased the rate of striatal dopamine disappearance following inhibition of tyrosine hydroxylase by h 44/68 without corresponding effect on hypothalamic and frontal cortical noradrenaline disappearance. |
1990-01-08 |
2023-08-11 |
rat |