| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| S A Berry, G A Gudelsk. D1 receptors function to inhibit the activation of tuberoinfundibular dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:1974647. |
), a dopamine antagonist with high affinity for d1 receptors, prevented the inhibitory effect of cy 208-243 on the haloperidol-induced activation of tyrosine hydroxylase in the median eminence. |
1990-09-17 |
2023-08-11 |
rat |
| S A Berry, G A Gudelsk. D1 receptors function to inhibit the activation of tuberoinfundibular dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:1974647. |
it is concluded that d1 receptor activation results in little or no effect on the basal rate of dopamine synthesis within tuberoinfundibular dopamine neurons, but under conditions in which the activity of tyrosine hydroxylase is increased d1 receptor stimulation results in a marked inhibition of the rate of dopamine synthesis within these neurons. |
1990-09-17 |
2023-08-11 |
rat |
| A S Tischler, L A Ruzicka, C S Van Pelt, G E Sandusk. Catecholamine-synthesizing enzymes and chromogranin proteins in drug-induced proliferative lesions of the rat adrenal medulla. Laboratory investigation; a journal of technical methods and pathology. vol 63. issue 1. 1990-08-24. PMID:1695697. |
sixteen of 17 pheochromocytomas and all hyperplastic nodules stained positively for tyrosine hydroxylase and dopamine beta-hydroxylase, consistent with an ability to produce ne. |
1990-08-24 |
2023-08-11 |
rat |
| R G Booth, R J Baldessarini, N S Kula, Y Gao, R Zong, J L Neumeye. Presynaptic inhibition of dopamine synthesis in rat striatal tissue by enantiomeric mono- and dihydroxyaporphines. Molecular pharmacology. vol 38. issue 1. 1990-08-21. PMID:1973525. |
presynaptic autoreceptor-mediated modulation of dopamine (da) synthesis was evaluated as the inhibition of tyrosine hydroxylase activity by enantiomeric mono- and dihydroxyaporphines with minced striatal tissue from rat brain. |
1990-08-21 |
2023-08-11 |
rat |
| M Manier, C Feuerstein, J G Passagia, P Mouchet, N Mons, M Geffard, J Thibaul. Evidence for the existence of L-dopa- and dopamine-immunoreactive nerve cell bodies in the caudal part of the dorsal motor nucleus of the vagus nerve. Journal of chemical neuroanatomy. vol 3. issue 3. 1990-08-13. PMID:1973044. |
adjacent serial cryostat sections from the medulla oblongata and from the cervical spinal cord were treated either for choline acetyltransferase immunohistochemistry, aromatic l-amino acid decarboxylase and tyrosine hydroxylase immunolabelling or for tyrosine hydroxylase, dopamine, noradrenaline and l-dihydroxyphenylalanine (dopa) immunostaining. |
1990-08-13 |
2023-08-11 |
rat |
| M Manier, C Feuerstein, J G Passagia, P Mouchet, N Mons, M Geffard, J Thibaul. Evidence for the existence of L-dopa- and dopamine-immunoreactive nerve cell bodies in the caudal part of the dorsal motor nucleus of the vagus nerve. Journal of chemical neuroanatomy. vol 3. issue 3. 1990-08-13. PMID:1973044. |
in the light of previous data showing colocalization of tyrosine hydroxylase and choline acetyltransferase in neurons of this portion of the nucleus, colocalization of dopamine with acetylcholine appears most likely. |
1990-08-13 |
2023-08-11 |
rat |
| B D Sloley, A V Juorio, D A Durde. High-performance liquid chromatographic analysis of monoamines and some of their gamma-glutamyl conjugates produced by the brain and other tissues of Helix aspersa (Gastropoda). Cellular and molecular neurobiology. vol 10. issue 2. 1990-08-13. PMID:2114217. |
treatment with blockers of tyrosine hydroxylase and aromatic-l-amino acid decarboxylase reduced dopamine concentrations without affecting 5-hydroxytryptamine. |
1990-08-13 |
2023-08-11 |
Not clear |
| K Shirasu, W E Stumpf, M Sa. Evidence for direct action of estradiol on growth hormone-releasing factor (GRF) in rat hypothalamus: localization of [3H]estradiol in GRF neurons. Endocrinology. vol 127. issue 1. 1990-08-08. PMID:1972921. |
the brain autoradiograms were immunostained for grf, srif, and tyrosine hydroxylase [th; an enzyme for the synthesis of dopamine (da)], and the pituitary autoradiograms were immunostained for gh by the avidin-biotin peroxidase method. |
1990-08-08 |
2023-08-11 |
rat |
| A Bjurholm, A Kreicbergs, M Ahmed, M Schultzber. Noradrenergic and peptidergic nerves in the synovial membrane of the Sprague-Dawley rat. Arthritis and rheumatism. vol 33. issue 6. 1990-08-06. PMID:1973038. |
similarly, tyrosine hydroxylase and dopamine beta-hydroxylase, which reflect the presence of noradrenaline, were colocalized with neuropeptide y. |
1990-08-06 |
2023-08-11 |
rat |
| C R Martling, R Matran, K Alving, T Hökfelt, J M Lundber. Innervation of lower airways and neuropeptide effects on bronchial and vascular tone in the pig. Cell and tissue research. vol 260. issue 2. 1990-08-01. PMID:1694104. |
the occurrence and distribution of peptide-containing nerve fibres [substance p (sp), calcitonin gene-related peptide (cgrp), vasoactive intestinal polypeptide (vip), peptide histidine isoleucine (phi), neuropeptide y (npy)] and noradrenergic nerve fibres [tyrosine hydroxylase (th)- and dopamine beta hydroxylase (dbh)-positive] in the airways of the pig were studied by means of immunohistochemistry. |
1990-08-01 |
2023-08-11 |
Not clear |
| I Wulle, M Kirsch, H J Wagne. Cyclic changes in dopamine and DOPAC content, and tyrosine hydroxylase activity in the retina of a cichlid fish. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972642. |
cyclic changes in dopamine and dopac content, and tyrosine hydroxylase activity in the retina of a cichlid fish. |
1990-08-01 |
2023-08-11 |
Not clear |
| I Wulle, M Kirsch, H J Wagne. Cyclic changes in dopamine and DOPAC content, and tyrosine hydroxylase activity in the retina of a cichlid fish. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972642. |
using high-performance liquid chromatography combined with electrochemical detection (hplc-ed) we measured the content of dopamine and 3,4-dihydroxyphenylacetic acid (dopac) as well as the activity of tyrosine hydroxylase in the retina of a teleost fish during a normal 12 h dark-light cycle. |
1990-08-01 |
2023-08-11 |
Not clear |
| I Wulle, M Kirsch, H J Wagne. Cyclic changes in dopamine and DOPAC content, and tyrosine hydroxylase activity in the retina of a cichlid fish. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:1972642. |
while tyrosine hydroxylase activity levels roughly paralleled dopamine values, the time course of dopac content was a mirror image of dopamine levels. |
1990-08-01 |
2023-08-11 |
Not clear |
| K J Axt, D L Commins, G Vosmer, L S Seide. alpha-Methyl-p-tyrosine pretreatment partially prevents methamphetamine-induced endogenous neurotoxin formation. Brain research. vol 515. issue 1-2. 1990-08-01. PMID:2113413. |
depletion of brain dopamine (da) by pretreatment with the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine (amt) has been shown to prevent the long-term neurotoxic effects of methamphetamine (ma). |
1990-08-01 |
2023-08-11 |
Not clear |
| D Martínez-Fong, M E Gutiérrez, J Aceve. Effect of chronic lead exposure on biopterin metabolism in the rat neostriatum. Journal of neuroscience research. vol 26. issue 1. 1990-07-31. PMID:2359144. |
these results suggest that lead intoxication may enhance dopamine metabolism in neostriatum by increasing the content of tetrahydrobiopterin, the regulating cofactor of tyrosine hydroxylase activity. |
1990-07-31 |
2023-08-11 |
rat |
| D Otto, K Unsicke. Basic FGF reverses chemical and morphological deficits in the nigrostriatal system of MPTP-treated mice. The Journal of neuroscience : the official journal of the Society for Neuroscience. vol 10. issue 6. 1990-07-26. PMID:1972393. |
simultaneous bfgf/mptp treatment diminished bilaterally the reduction of striatal dopamine (da) levels observed in cytochrome c/mptp-treated mice and led to an ipsilateral reappearance of tyrosine hydroxylase (th)-like immunoreactive fibers, most notably adjacent to the implant, 2 weeks after the surgery. |
1990-07-26 |
2023-08-11 |
mouse |
| P J Hornby, D T Pieku. Distribution of catecholamine-synthesizing enzymes in goldfish brains: presumptive dopamine and norepinephrine neuronal organization. Brain, behavior and evolution. vol 35. issue 1. 1990-06-27. PMID:1971189. |
the organization of presumptive dopamine- and norepinephrine-synthesizing neurons in the brains of goldfish is described by using antibodies to tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) with avidin-biotin immunocytochemical techniques. |
1990-06-27 |
2023-08-11 |
Not clear |
| F C Liu, A M Graybiel, S B Dunnett, R W Baughma. Intrastriatal grafts derived from fetal striatal primordia: II. Reconstitution of cholinergic and dopaminergic systems. The Journal of comparative neurology. vol 295. issue 1. 1990-06-27. PMID:1971286. |
for the dopaminergic system, a comparable modular organization was found in the grafts by immunostaining for tyrosine hydroxylase, the catecholamine synthetic enzyme; by autoradiographic [3h]mazindol binding for dopamine uptake sites; and by [3h]sch23390 binding for dopamine d1 receptors and [3h]sulpiride binding for dopamine d2 receptors. |
1990-06-27 |
2023-08-11 |
rat |
| S L Cottingham, D Pickar, T K Shimotake, P Montpied, S M Paul, J N Crawle. Tyrosine hydroxylase and cholecystokinin mRNA levels in the substantia nigra, ventral tegmental area, and locus ceruleus are unaffected by acute and chronic haloperidol administration. Cellular and molecular neurobiology. vol 10. issue 1. 1990-06-14. PMID:1970757. |
these data suggest that haloperidol administration does not alter the level of tyrosine hydroxylase or cholecystokinin mrnas in midbrain dopamine neurons of the rat. |
1990-06-14 |
2023-08-11 |
rat |
| Y Masuo, D Pélaprat, M N Montagne, D Scherman, W Rostèn. Regulation of neurotensin-containing neurons in the rat striatum and substantia nigra. Effects of unilateral nigral lesion with 6-hydroxydopamine on neurotensin content and its binding site density. Brain research. vol 510. issue 2. 1990-06-04. PMID:1970504. |
tyrosine hydroxylase (t-oh) activity, gamma-aminobutyric acid (gaba) content, binding site densities of dihydrotetrabenazine (tbzoh), a marker of dopaminergic synaptic vesicles, and of iodosulpiride, a ligand for dopamine d2 receptors, were also determined. |
1990-06-04 |
2023-08-11 |
rat |