| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| P Soares-da-Silva, M C Garret. A kinetic study of the rate of formation of dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the brain of the rat: implications for the origin of DOPAC. Neuropharmacology. vol 29. issue 10. 1991-01-24. PMID:1979427. |
levels of dopamine, dopac and hva in tissue were logarithmically transformed, plotted against the duration of inhibition of tyrosine hydroxylase and the rate constant of the decline of dopamine and of its metabolites calculated. |
1991-01-24 |
2023-08-11 |
rat |
| F Javoy-Agid, E C Hirsch, S Dumas, C Duyckaerts, J Mallet, Y Agi. Decreased tyrosine hydroxylase messenger RNA in the surviving dopamine neurons of the substantia nigra in Parkinson's disease: an in situ hybridization study. Neuroscience. vol 38. issue 1. 1991-01-24. PMID:1979431. |
decreased tyrosine hydroxylase messenger rna in the surviving dopamine neurons of the substantia nigra in parkinson's disease: an in situ hybridization study. |
1991-01-24 |
2023-08-11 |
Not clear |
| R Strong, M A Moore, C Hale, M Wessels-Reiker, H J Armbrecht, A Richardso. Modulation of tyrosine hydroxylase gene expression in the rat adrenal gland by age and reserpine. Brain research. vol 525. issue 1. 1991-01-08. PMID:1978789. |
tyrosine hydroxylase (th), th messenger rna (th mrna) and dopamine (da) were measured simultaneously in adrenal glands of individual fischer 344 rats aged 2, 6, 13 and 23 months. |
1991-01-08 |
2023-08-11 |
rat |
| D J Sirinathsinghji, S B Dunnett, A J Northrop, B J Morri. Experimental hemiparkinsonism in the rat following chronic unilateral infusion of MPP+ into the nigrostriatal dopamine pathway--III. Reversal by embryonic nigral dopamine grafts. Neuroscience. vol 37. issue 3. 1991-01-08. PMID:2247221. |
in all the animals that received nigral dopamine grafts, numerous cells were localized within the grafts which contained tyrosine hydroxylase immunoreactivity and tyrosine hydroxylase mrna. |
1991-01-08 |
2023-08-11 |
rat |
| J W Gibb, M Johnson, G R Hanso. Neurochemical basis of neurotoxicity. Neurotoxicology. vol 11. issue 2. 1990-12-07. PMID:1978271. |
meth decreased activities of tyrosine hydroxylase and tryptophan hydroxylase; concentrations of dopamine (da) and 5-hydroxytryptamine (5ht) and their respective metabolites were decreased in parallel with the decline in activity of the enzymes. |
1990-12-07 |
2023-08-11 |
Not clear |
| H Bake. Unilateral, neonatal olfactory deprivation alters tyrosine hydroxylase expression but not aromatic amino acid decarboxylase or GABA immunoreactivity. Neuroscience. vol 36. issue 3. 1990-12-06. PMID:1700334. |
immunoreactivity of tyrosine hydroxylase, the first and rate-limiting enzyme in dopamine biosynthesis, used as a marker of the dopamine system, exhibited a large decrease both 40 and 70 days following olfactory deprivation. |
1990-12-06 |
2023-08-11 |
rat |
| M Poltorak, W J Free. Cell adhesion molecules in adrenal medulla grafts: enhancement of chromaffin cell L1/Ng-CAM expression and reorganization of extracellular matrix following transplantation. Experimental neurology. vol 110. issue 1. 1990-11-21. PMID:2209783. |
the cells retained tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh) immunoreactivity, while phenylethanolamine n-methyltransferase (pnmt) expression was decreased. |
1990-11-21 |
2023-08-11 |
human |
| C J Mathias, R B Bannister, P Cortelli, K Heslop, J M Polak, S Raimbach, D R Springall, L Watso. Clinical, autonomic and therapeutic observations in two siblings with postural hypotension and sympathetic failure due to an inability to synthesize noradrenaline from dopamine because of a deficiency of dopamine beta hydroxylase. The Quarterly journal of medicine. vol 75. issue 278. 1990-11-14. PMID:2217667. |
immunohistochemical studies of perivascular cutaneous tissue confirmed normal peptidergic and tyrosine hydroxylase immunoreactivity, with absent dopamine beta-hydroxylase immunoreactivity. |
1990-11-14 |
2023-08-11 |
Not clear |
| J M Woulfe, B A Flumerfelt, A W Hrycyshy. Efferent connections of the A1 noradrenergic cell group: a DBH immunohistochemical and PHA-L anterograde tracing study. Experimental neurology. vol 109. issue 3. 1990-11-07. PMID:1976532. |
immunohistochemical localization of the catecholamine biosynthetic enzymes tyrosine hydroxylase (th), dopamine beta-hydroxylase (dbh), and phenylethanolamine n-methyltransferase (pnmt) was employed to reveal the anatomical organization of the a1 noradrenergic cell group in the caudal ventrolateral medulla oblongata of the rat. |
1990-11-07 |
2023-08-11 |
rat |
| W J Smeets, A Gonzale. Are putative dopamine-accumulating cell bodies in the hypothalamic periventricular organ a primitive brain character of non-mammalian vertebrates? Neuroscience letters. vol 114. issue 3. 1990-10-24. PMID:1976236. |
the brains of the chicken, gallus domesticus, and two amphibians, the anuran rana ridibunda and the urodele pleurodeles waltlii, were investigated by means of immunohistochemical techniques with antibodies against dopamine (da) and tyrosine hydroxylase (th). |
1990-10-24 |
2023-08-11 |
chicken |
| P Bałuk, G Gabell. Some parasympathetic neurons in the guinea-pig heart express aspects of the catecholaminergic phenotype in vivo. Cell and tissue research. vol 261. issue 2. 1990-10-22. PMID:1976043. |
however, these neurons do not contain tyrosine hydroxylase and show little or no histochemically detectable uptake of alpha-methyldopa, dopamine or noradrenaline, even after depletion of endogenous stores of amines by pre-treatment with reserpine. |
1990-10-22 |
2023-08-11 |
Not clear |
| E J Kilbourne, E L Sabba. Differential effect of membrane depolarization on levels of tyrosine hydroxylase and dopamine beta-hydroxylase mRNAs in PC12 pheochromocytoma cells. Brain research. Molecular brain research. vol 8. issue 2. 1990-10-19. PMID:1976198. |
differential effect of membrane depolarization on levels of tyrosine hydroxylase and dopamine beta-hydroxylase mrnas in pc12 pheochromocytoma cells. |
1990-10-19 |
2023-08-11 |
Not clear |
| E J Kilbourne, E L Sabba. Differential effect of membrane depolarization on levels of tyrosine hydroxylase and dopamine beta-hydroxylase mRNAs in PC12 pheochromocytoma cells. Brain research. Molecular brain research. vol 8. issue 2. 1990-10-19. PMID:1976198. |
we studied the effect of treating pc12 cells with membrane depolarizing stimuli, 50 mm kcl, or 150 microm veratridine, and the subsequent changes in the mrna levels of the catecholamine biosynthetic enzymes, tyrosine hydroxylase (th) and dopamine beta-hydroxylase (dbh). |
1990-10-19 |
2023-08-11 |
Not clear |
| J F Coulon, N F Biguet, A Cavoy, J Delacour, J Mallet, J C Davi. Gene expression of tyrosine hydroxylase in the developing fetal brain. Journal of neurochemistry. vol 55. issue 4. 1990-10-17. PMID:1975836. |
tyrosine hydroxylase, aromatic l-amino-acid decarboxylase, and dopamine beta-hydroxylase activities were studied in the developing fetal rat brain. |
1990-10-17 |
2023-08-11 |
rat |
| J F Coulon, N F Biguet, A Cavoy, J Delacour, J Mallet, J C Davi. Gene expression of tyrosine hydroxylase in the developing fetal brain. Journal of neurochemistry. vol 55. issue 4. 1990-10-17. PMID:1975836. |
a delay of 2-3 days between the detection of the tyrosine hydroxylase and the aromatic l-amino-acid decarboxylase and dopamine beta-hydroxylase activities was observed. |
1990-10-17 |
2023-08-11 |
rat |
| W W Morgan, K C Besc. Effect of prolactin replacement on the number of tyrosine hydroxylase expressing neurons in the arcuate nuclei of Ames dwarf and normal mice. Neuroendocrinology. vol 52. issue 1. 1990-10-10. PMID:1975656. |
an antibody to tyrosine hydroxylase (th), the rate-limiting enzyme in the biosynthesis of dopamine, and immunohistochemical procedures were used in this study to compare the numbers of th-immuno-positive neurons observed in the arcuate nuclei of ames dwarf mice compared to phenotypically normal mice of the same strain. |
1990-10-10 |
2023-08-11 |
mouse |
| L J Ryan, J C Linder, M E Martone, P M Grove. Histological and ultrastructural evidence that D-amphetamine causes degeneration in neostriatum and frontal cortex of rats. Brain research. vol 518. issue 1-2. 1990-10-04. PMID:1975218. |
in contrast, the damage in neostriatum probably includes damage to dopamine axonal terminals since tyrosine hydroxylase immunolabeling was patchy with many swollen and distorted labeled axons. |
1990-10-04 |
2023-08-11 |
rat |
| K Kitahama, M Geffard, H Okamura, I Nagatsu, N Mons, M Jouve. Dopamine- and dopa-immunoreactive neurons in the cat forebrain with reference to tyrosine hydroxylase-immunohistochemistry. Brain research. vol 518. issue 1-2. 1990-10-04. PMID:1975219. |
the distribution of cell bodies containing immunoreactivities to dopamine (da), l-3,4-dihydroxyphenylalanine (dopa) and tyrosine hydroxylase (th) was studied immunohistochemically in the cat forebrain especially in the hypothalamus with or without intraventricular administration of colchicine. |
1990-10-04 |
2023-08-11 |
rat |
| K Hozawa, R S Kimur. Cholinergic and noradrenergic nervous systems in the cynomolgus monkey cochlea. Acta oto-laryngologica. vol 110. issue 1-2. 1990-09-20. PMID:1974732. |
the cholinergic and noradrenergic nervous systems in the cochleas of cynomolgus monkeys were examined by histochemical and immunohistochemical demonstration of acetylcholinesterase (ache) and tyrosine hydroxylase (th) and/or dopamine b-hydroxylase (dbh), respectively. |
1990-09-20 |
2023-08-11 |
monkey |
| S A Berry, G A Gudelsk. D1 receptors function to inhibit the activation of tuberoinfundibular dopamine neurons. The Journal of pharmacology and experimental therapeutics. vol 254. issue 2. 1990-09-17. PMID:1974647. |
the effects of the d1 dopamine agonists skf 38393 and cy 208-243 on the activity of tyrosine hydroxylase within tuberoinfundibular dopamine neurons were studied by measuring the accumulation of dihydroxyphenylalanine (dopa) in the median eminence in vivo after inhibition of dopa decarboxylase. |
1990-09-17 |
2023-08-11 |
rat |