| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| L T Weiss-Wunder, M F Chessele. Subpopulations of mesencephalic dopaminergic neurons express different levels of tyrosine hydroxylase messenger RNA. The Journal of comparative neurology. vol 303. issue 3. 1991-05-01. PMID:1672536. |
differences in levels of labelling for messenger rna in mesencephalic dopamine neurons were not related to differences in cell size as measured in sections processed for tyrosine hydroxylase immunohistochemistry. |
1991-05-01 |
2023-08-11 |
mouse |
| L T Weiss-Wunder, M F Chessele. Subpopulations of mesencephalic dopaminergic neurons express different levels of tyrosine hydroxylase messenger RNA. The Journal of comparative neurology. vol 303. issue 3. 1991-05-01. PMID:1672536. |
the results suggest that tyrosine hydroxylase messenger rna is differentially regulated in subpopulations of mesencephalic dopamine neurons, supporting the view that these neurons are physiologically distinct. |
1991-05-01 |
2023-08-11 |
mouse |
| I Date, M F Notter, S Y Felten, D L Felte. MPTP-treated young mice but not aging mice show partial recovery of the nigrostriatal dopaminergic system by stereotaxic injection of acidic fibroblast growth factor (aFGF). Brain research. vol 526. issue 1. 1991-04-26. PMID:1706636. |
given 12 h apart) reduced tyrosine hydroxylase (th)-immunoreactive (ir) fibers in the striatum and reduced dopamine (da) concentration to 32% of the controls in young and 20% of the controls in aging mouse brain 5 weeks after administration. |
1991-04-26 |
2023-08-11 |
mouse |
| K T Keyser, L R Britto, J I Woo, D H Park, T H Joh, H J Karte. Presumptive catecholaminergic ganglion cells in the pigeon retina. Visual neuroscience. vol 4. issue 3. 1991-04-26. PMID:1981838. |
an antiserum directed against tyrosine hydroxylase (th), the rate-limiting enzyme in the synthesis of dopamine, was used to study the pigeon retina. |
1991-04-26 |
2023-08-11 |
pigeon |
| M E Wolf, P A LeWitt, M J Bannon, L J Dragovic, G Kapato. Effect of aging on tyrosine hydroxylase protein content and the relative number of dopamine nerve terminals in human caudate. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1672141. |
effect of aging on tyrosine hydroxylase protein content and the relative number of dopamine nerve terminals in human caudate. |
1991-04-15 |
2023-08-11 |
human |
| M E Wolf, P A LeWitt, M J Bannon, L J Dragovic, G Kapato. Effect of aging on tyrosine hydroxylase protein content and the relative number of dopamine nerve terminals in human caudate. Journal of neurochemistry. vol 56. issue 4. 1991-04-15. PMID:1672141. |
this study examined the effect of aging on the relative number of dopamine (da) nerve terminals in human caudate nucleus, their content of tyrosine hydroxylase (th) protein, and the relative abundance of th monomers with different molecular weights. |
1991-04-15 |
2023-08-11 |
human |
| P Horellou, L Marlier, A Privat, F Darchen, D Scherman, J P Henry, J Malle. Exogeneous expression of L-dopa and dopamine in various cell lines following transfer of rat and human tyrosine hydroxylase cDNA: grafting in an animal model of Parkinson's disease. Progress in brain research. vol 82. 1991-04-04. PMID:1981276. |
exogeneous expression of l-dopa and dopamine in various cell lines following transfer of rat and human tyrosine hydroxylase cdna: grafting in an animal model of parkinson's disease. |
1991-04-04 |
2023-08-11 |
human |
| P K Sonsalla, D E Riordan, R E Heikkil. Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice. The Journal of pharmacology and experimental therapeutics. vol 256. issue 2. 1991-03-21. PMID:1671596. |
for example, several compounds which bind to the phenyclidine site within the ion channel linked to the n-methyl-d-aspartate (nmda) receptor protected mice from the meth-induced loss of neostriatal tyrosine hydroxylase activity and dopamine content. |
1991-03-21 |
2023-08-11 |
mouse |
| P K Sonsalla, D E Riordan, R E Heikkil. Competitive and noncompetitive antagonists at N-methyl-D-aspartate receptors protect against methamphetamine-induced dopaminergic damage in mice. The Journal of pharmacology and experimental therapeutics. vol 256. issue 2. 1991-03-21. PMID:1671596. |
the administration of three or four injections of meth (10 mg/kg) every 2 hr to mice produced large decrements in neostriatal dopamine content (80-84%) and in tyrosine hydroxylase activity (65-74%). |
1991-03-21 |
2023-08-11 |
mouse |
| R Roskoski, P Ritchi. Phosphorylation of rat tyrosine hydroxylase and its model peptides in vitro by cyclic AMP-dependent protein kinase. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1671583. |
the enzyme tyrosine hydroxylase catalyzes the first step in the biosynthesis of dopamine, norepinephrine, and epinephrine. |
1991-03-15 |
2023-08-11 |
rat |
| R Roskoski, P Ritchi. Phosphorylation of rat tyrosine hydroxylase and its model peptides in vitro by cyclic AMP-dependent protein kinase. Journal of neurochemistry. vol 56. issue 3. 1991-03-15. PMID:1671583. |
these values were not appreciably affected by the substrates for tyrosine hydroxylase (tyrosine and tetrahydrobiopterin) or by feedback inhibitors (dopamine and norepinephrine). |
1991-03-15 |
2023-08-11 |
rat |
| N Ochi, M Naoi, M Mogi, Y Ohya, N Mizutani, K Watanabe, M Harada, T Nagats. Effects of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP) administration in prenatal stage on the dopamine system in the postnatal mouse brain. Life sciences. vol 48. issue 3. 1991-03-13. PMID:1671518. |
dopamine levels and tyrosine hydroxylase (th) activity were measured in the whole brain from the pups sacrificed after birth. |
1991-03-13 |
2023-08-11 |
mouse |
| P M Iuvone, M Tigges, A Fernandes, J Tigge. Dopamine synthesis and metabolism in rhesus monkey retina: development, aging, and the effects of monocular visual deprivation. Visual neuroscience. vol 2. issue 5. 1991-03-13. PMID:2577263. |
the level of the dopamine metabolite 3,4-dihydroxyphenylacetic acid (dopac) and the activity of tyrosine hydroxylase did not significantly change as a function of age during the postnatal life span. |
1991-03-13 |
2023-08-11 |
monkey |
| P M Iuvone, M Tigges, A Fernandes, J Tigge. Dopamine synthesis and metabolism in rhesus monkey retina: development, aging, and the effects of monocular visual deprivation. Visual neuroscience. vol 2. issue 5. 1991-03-13. PMID:2577263. |
monocular eyelid suture from birth to 15 months of age resulted in less consistent alterations of retinal dopamine and dopac levels; tyrosine hydroxylase activity, however, was consistently reduced by lid suture. |
1991-03-13 |
2023-08-11 |
monkey |
| M Cebeira, M L Hernandez, F Rodriguez de Fonseca, R de Miguel, J J Fernandez-Ruiz, J A Ramo. Lack of effect of prolactin on the dopaminergic receptor sensitivity in striatal and limbic areas after experimentally-induced alterations in its peripheral levels. Life sciences. vol 48. issue 6. 1991-03-08. PMID:1671524. |
tyrosine hydroxylase (th) activity and dopamine (da) and l-3,4-dihydroxyphenylacetic acid (dopac) content were also measured as indices of presynaptic activity. |
1991-03-08 |
2023-08-11 |
rat |
| G Buzsáki, I Laszlovszky, A Lajtha, C Vadás. Spike-and-wave neocortical patterns in rats: genetic and aminergic control. Neuroscience. vol 38. issue 2. 1991-02-01. PMID:2263319. |
in addition, tyrosine hydroxylase activity and dopamine d2 receptor density were determined in the substantia nigra, corpus striatum, olfactory tubercle and ponsmedulla areas of fisher 344 and buffalo animals. |
1991-02-01 |
2023-08-11 |
human |
| R M Torack, J C Morri. Tyrosine hydroxylase-like (TH) immunoreactivity in human mesolimbic system. Neuroscience letters. vol 116. issue 1-2. 1991-01-28. PMID:1979668. |
a practical methodology has been described for the use of human postmortem brain tissue in both tyrosine hydroxylase and dopamine beta-hydroxylase immunohistochemistry in which in situ perfusion with paraformaldehyde is followed by immersion fixation in bouin's fixative. |
1991-01-28 |
2023-08-11 |
human |
| R G Booth, R J Baldessarin. Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation. European journal of pharmacology. vol 185. issue 2-3. 1991-01-24. PMID:1979274. |
adenosine a2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine d2 autoreceptor activation. |
1991-01-24 |
2023-08-11 |
rat |
| R G Booth, R J Baldessarin. Adenosine A2 stimulation of tyrosine hydroxylase in rat striatal minces is reversed by dopamine D2 autoreceptor activation. European journal of pharmacology. vol 185. issue 2-3. 1991-01-24. PMID:1979274. |
the adenosine agonist, 2-chloroadenosine, stimulated tyrosine hydroxylase activity in rat striatal minces; this effect was attenuated by activation of dopamine (da) d2 autoreceptors with n-n-propylnorapomorphine and antagonized by theophylline. |
1991-01-24 |
2023-08-11 |
rat |
| P Soares-da-Silva, M C Garret. A kinetic study of the rate of formation of dopamine, 3,4-dihydroxyphenylacetic acid (DOPAC) and homovanillic acid (HVA) in the brain of the rat: implications for the origin of DOPAC. Neuropharmacology. vol 29. issue 10. 1991-01-24. PMID:1979427. |
the rates of disappearance of dopamine, 3,4-dihydroxyphenylacetic acid (dopac) and homovanillic acid (hva) in the brain of rats treated with the tyrosine hydroxylase inhibitor alpha-methyl-p-tyrosine were measured. |
1991-01-24 |
2023-08-11 |
rat |