| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martin Muurling, Ronald P Mensink, Hanno Pijl, Johannes A Romijn, Louis M Havekes, Peter J Vosho. Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice. Metabolism: clinical and experimental. vol 52. issue 8. 2003-09-25. PMID:12898477. |
we conclude that rosiglitazone treatment leads to strong improvement of insulin sensitivity, irrespective of increased muscle tg content, in ob/ob mice. |
2003-09-25 |
2023-08-12 |
mouse |
| Yumiko Hiura, Fay Acklin, Jennifer Newman, Kate Steinbeck, Ian D Caterson, Deepika Mahajan, Kaye Brock, Margaret A Bermingha. Hypertriglyceridemic waist as a screening tool for CVD risk in indigenous Australian women. Ethnicity & disease. vol 13. issue 1. 2003-09-02. PMID:12723016. |
research has demonstrated that the simultaneous determination of waist circumference and fasting plasma triglyceride (tg) concentrations can identify men characterized by a metabolic triad of unconventional risk variables: increased levels of fasting insulin, apolipoprotein (apo) b, and a predominance of small, dense, low density lipoprotein (ldl) particles. |
2003-09-02 |
2023-08-12 |
human |
| Yumiko Hiura, Fay Acklin, Jennifer Newman, Kate Steinbeck, Ian D Caterson, Deepika Mahajan, Kaye Brock, Margaret A Bermingha. Hypertriglyceridemic waist as a screening tool for CVD risk in indigenous Australian women. Ethnicity & disease. vol 13. issue 1. 2003-09-02. PMID:12723016. |
fasting insulin levels were higher with increasing waist girth, but not with increasing tg levels. |
2003-09-02 |
2023-08-12 |
human |
| Peter J Voshol, Guenter Haemmerle, D Margriet Ouwens, Robert Zimmermann, Rudolf Zechner, Bas Teusink, J Antonie Maassen, Louis M Havekes, Johannes A Romij. Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice. Endocrinology. vol 144. issue 8. 2003-08-29. PMID:12865325. |
because a decreased hepatic insulin sensitivity has been reported to be associated with high liver tg levels, our aim was to determine whether a hepatic tg content lower than normal, as observed in hsl-knockout mice, leads to increased hepatic insulin sensitivity. |
2003-08-29 |
2023-08-12 |
mouse |
| Peter J Voshol, Guenter Haemmerle, D Margriet Ouwens, Robert Zimmermann, Rudolf Zechner, Bas Teusink, J Antonie Maassen, Louis M Havekes, Johannes A Romij. Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice. Endocrinology. vol 144. issue 8. 2003-08-29. PMID:12865325. |
in hsl-knockout mice, reduced hepatic tg stores result in an increased suppressive effect of insulin on hepatic glucose production, in line with an increased hepatic pkb-p/akt and phosphatidylinositol-3 kinase activity. |
2003-08-29 |
2023-08-12 |
mouse |
| Peter J Voshol, Guenter Haemmerle, D Margriet Ouwens, Robert Zimmermann, Rudolf Zechner, Bas Teusink, J Antonie Maassen, Louis M Havekes, Johannes A Romij. Increased hepatic insulin sensitivity together with decreased hepatic triglyceride stores in hormone-sensitive lipase-deficient mice. Endocrinology. vol 144. issue 8. 2003-08-29. PMID:12865325. |
thus, hepatic insulin sensitivity is indeed increased after reducing hepatic tg stores below normal. |
2003-08-29 |
2023-08-12 |
mouse |
| Mark O Goodarzi, Stephen Erickson, Sidney C Port, Robert I Jennrich, Stanley G Korenma. Relative impact of insulin resistance and obesity on cardiovascular risk factors in polycystic ovary syndrome. Metabolism: clinical and experimental. vol 52. issue 6. 2003-07-11. PMID:12800096. |
insulin resistance, not bmi, was the main determinant of hdl-c and tg levels and systolic blood pressure (sbp) in pcos. |
2003-07-11 |
2023-08-12 |
Not clear |
| I Sánchez-Vera, B Bonet, M Viana, E Herrera, A Indar. Effect of acipimox on plasma lipids and glucose/insulin in pregnant rats. International journal of experimental diabetes research. vol 3. issue 4. 2003-07-07. PMID:12546276. |
over a short period of time, in pregnant rats, reductions of plasma ffa and tg after acipimox treatment improved the glucose-induced insulin release, but did not seem to have any effect in peripheral insulin resistance. |
2003-07-07 |
2023-08-12 |
rat |
| Chin-Hsiao Tsen. Prevalence and risk factors of peripheral arterial obstructive disease in Taiwanese type 2 diabetic patients. Angiology. vol 54. issue 3. 2003-07-03. PMID:12785026. |
risk factors studied were age, sex, body mass index (bmi), smoking, diabetes duration, hypertension, insulin therapy, systolic blood pressure (sbp), diastolic blood pressure (dbp), fasting plasma glucose (fpg), serum total cholesterol (tc), and triglyceride (tg). |
2003-07-03 |
2023-08-12 |
Not clear |
| Edwige Bailhache, Patrick Nguyen, Michel Krempf, Brigitte Siliart, Thierry Magot, Khadija Ouguerra. Lipoproteins abnormalities in obese insulin-resistant dogs. Metabolism: clinical and experimental. vol 52. issue 5. 2003-06-27. PMID:12759884. |
low insulin sensitivity associated with obesity was related to an increase in plasma triglyceride (tg) through an increase in very-low-density lipoprotein (vldl)-tg (0.071 +/- 0.020 v 0.382 +/- 0.242 mmol/l, p <.05) and high-density lipoprotein (hdl)-tg (0.025 +/- 0.012 v 0.242 +/- 0.143 mmol/l, p <.05). |
2003-06-27 |
2023-08-12 |
dog |
| E Moro, P Gallina, M Pais, G Cazzolato, P Alessandrini, G Bittolo-Bo. Hypertriglyceridemia is associated with increased insulin resistance in subjects with normal glucose tolerance: evaluation in a large cohort of subjects assessed with the 1999 World Health Organization criteria for the classification of diabetes. Metabolism: clinical and experimental. vol 52. issue 5. 2003-06-27. PMID:12759893. |
the current study retrospectively examined the association between insulin resistance and plasma triglycerides (tg) in a group of subjects with normal glucose tolerance. |
2003-06-27 |
2023-08-12 |
human |
| E Moro, P Gallina, M Pais, G Cazzolato, P Alessandrini, G Bittolo-Bo. Hypertriglyceridemia is associated with increased insulin resistance in subjects with normal glucose tolerance: evaluation in a large cohort of subjects assessed with the 1999 World Health Organization criteria for the classification of diabetes. Metabolism: clinical and experimental. vol 52. issue 5. 2003-06-27. PMID:12759893. |
insulin resistance, calculated as homa(ir), was higher in the upper two tertiles of tg in comparison to the lower tertile (p <.001 and p <.0001, respectively), with a statistically significant trend for the entire group (first tertile, 1.85 +/- 0.94; second tertile, 2.28 +/- 1.10; third tertile, 2.65 +/- 1.71; anova: p <.0001). |
2003-06-27 |
2023-08-12 |
human |
| E Moro, P Gallina, M Pais, G Cazzolato, P Alessandrini, G Bittolo-Bo. Hypertriglyceridemia is associated with increased insulin resistance in subjects with normal glucose tolerance: evaluation in a large cohort of subjects assessed with the 1999 World Health Organization criteria for the classification of diabetes. Metabolism: clinical and experimental. vol 52. issue 5. 2003-06-27. PMID:12759893. |
in conclusion, this study shows an association between high levels of circulating tg and insulin resistance in patients with normal glucose tolerance seen in an atherosclerosis prevention clinic. |
2003-06-27 |
2023-08-12 |
human |
| Douglas E Hughes, Donna Beer Stolz, Songtao Yu, Yongjun Tan, Janardan K Reddy, Simon C Watkins, Anna Mae Diehl, Robert H Cost. Elevated hepatocyte levels of the Forkhead box A2 (HNF-3beta) transcription factor cause postnatal steatosis and mitochondrial damage. Hepatology (Baltimore, Md.). vol 37. issue 6. 2003-06-18. PMID:12774021. |
adult tg mice exhibited reduced hepatic glycogen and progressive liver injury, but maintained normal serum levels of glucose, insulin, and glucagon. |
2003-06-18 |
2023-08-12 |
mouse |
| S R Kim, E O Talbott, E S Tull, J V Zborowski, M T Vogt, L H Kulle. Assessment of the disturbances in metabolic homeostasis: a hypothesis of synergism. Medical hypotheses. vol 59. issue 6. 2003-06-12. PMID:12445505. |
based on the hypothesis that a synergistic interaction between triiodothyronine (t(3)) and insulin contributes to abnormalities in glucose and other metabolic pathways, the mechanisms underlying the impairment of metabolic homeostasis (mh) and the development of type-2 diabetes (dm) were investigated via a proposed homeostatic model, [(fg*tg)/t3*fi)]. |
2003-06-12 |
2023-08-12 |
Not clear |
| S R Kim, E O Talbott, E S Tull, J V Zborowski, M T Vogt, L H Kulle. Assessment of the disturbances in metabolic homeostasis: a hypothesis of synergism. Medical hypotheses. vol 59. issue 6. 2003-06-12. PMID:12445505. |
the mh model characterizes the relationship between t(3) and insulin and the levels of triglycerides (tg), fasting insulin (fi), and fasting glucose (fg) and is introduced as a clinical method to assess insulin sensitivity and the status of metabolic homeostasis in lieu of current screening models advocated by the by american diabetic association (ada). |
2003-06-12 |
2023-08-12 |
Not clear |
| M Gaster, P D Ottosen, W Vach, H Christiansen, P Staehr, H Beck-Nielsen, H D Schrøde. GLUT4 expression in human muscle fibres is not correlated with intracellular triglyceride (TG) content. Is TG a maker or a marker of insulin resistance? APMIS : acta pathologica, microbiologica, et immunologica Scandinavica. vol 111. issue 2. 2003-06-12. PMID:12716391. |
is tg a maker or a marker of insulin resistance? |
2003-06-12 |
2023-08-12 |
human |
| Laura L Atkinson, Ray Kozak, Sandra E Kelly, Arzu Onay Besikci, James C Russell, Gary D Lopaschu. Potential mechanisms and consequences of cardiac triacylglycerol accumulation in insulin-resistant rats. American journal of physiology. Endocrinology and metabolism. vol 284. issue 5. 2003-05-21. PMID:12464581. |
the accumulation of intracellular triacylglycerol (tg) is highly correlated with muscle insulin resistance. |
2003-05-21 |
2023-08-12 |
rat |
| Gilberto Campos, Elena Ryder, María Diez-Ewald, Francisco Rivero, Virginia Fernández, Xiomara Raleigh, Carmen Luisa Arocha-Piñang. [Prevalence of obesity and hyperinsulinemia: its association with serum lipid and lipoprotein concentrations in healthy individuals from Maracaibo, Venezuela]. Investigacion clinica. vol 44. issue 1. 2003-05-20. PMID:12703179. |
all subjects underwent cardiovascular evaluation and laboratory examination after 10-12 h fasting, for glycaemia, total cholesterol, tg, vldl-c, ldl-c and hdl-c as well as insulin. |
2003-05-20 |
2023-08-12 |
human |
| Gilberto Campos, Elena Ryder, María Diez-Ewald, Francisco Rivero, Virginia Fernández, Xiomara Raleigh, Carmen Luisa Arocha-Piñang. [Prevalence of obesity and hyperinsulinemia: its association with serum lipid and lipoprotein concentrations in healthy individuals from Maracaibo, Venezuela]. Investigacion clinica. vol 44. issue 1. 2003-05-20. PMID:12703179. |
the insulin concentration in obese men correlated with bmi, tg, vldl-c and hdl and, in women with bmi, tg and vldl-c. |
2003-05-20 |
2023-08-12 |
human |