| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| C J M Halkes, J P H Van Wijk, J Ribalta, L Masana, M Castro Cabeza. Diurnal triglyceridaemia and insulin resistance in mildly obese subjects with normal fasting plasma lipids. Journal of internal medicine. vol 255. issue 1. 2004-03-08. PMID:14687241. |
we assessed the diurnal capillary tg (tgc) profile in males with mild obesity and evaluated the use of plasma and capillary tg as markers of insulin resistance. |
2004-03-08 |
2023-08-12 |
human |
| Masahiko Igarashi, Akihiko Hirata, Toshiyuki Yamauchi, Hiroshi Yamaguchi, Hiromi Tsuchiya, Hiroshi Ohnuma, Yumi Jimbu, Yoko Okuyama, Toru Shirata, Nobuhiro Otsu, Haru Fukuyama, Sachiko Takahashi, Makoto Tominaga, Takeo Kat. Clinical utility and approach to estimate postprandial hypertriglycemia by a newly designed oral fat-loading test. Journal of atherosclerosis and thrombosis. vol 10. issue 5. 2004-02-23. PMID:14718749. |
twenty-three healthy normolipidemic volunteers were orally administered a test meal consisting of a mixture of telmeal 2.0 and 20 g of salt-free butter after fasting for 12 h. to measure the levels of total cholesterol (t-cho), triglycerides (tg), high-density lipoprotein-cholesterol (hdl-c), remnant-like particle-cholesterol (rlp-c), lipoprotein (a) [lp (a)], free fatty acid, apolipoproteins (apos), plasma glucose (pg), immunoreactive insulin (iri), and high-sensitivity c-reactive protein (hs-crp), venous blood samples were collected before the meal and at each hour until 9 h after fat-loading. |
2004-02-23 |
2023-08-12 |
human |
| Toshimasa Yamauchi, Kazuo Hara, Naoto Kubota, Yasuo Terauchi, Kazuyuki Tobe, Philippe Froguel, Ryozo Nagai, Takashi Kadowak. Dual roles of adiponectin/Acrp30 in vivo as an anti-diabetic and anti-atherogenic adipokine. Current drug targets. Immune, endocrine and metabolic disorders. vol 3. issue 4. 2004-02-18. PMID:14683455. |
in muscle and liver, adiponectin activated amp kinase and pparalpha pathways thereby increasing beta-oxidation of lipids, leading to decreased tg content, which ameliorated insulin resistance under a high-fat diet. |
2004-02-18 |
2023-08-12 |
mouse |
| S Lindeberg, B Ahrén, A Nilsson, L Cordain, P Nilsson-Ehle, B Vessb. Determinants of serum triglycerides and high-density lipoprotein cholesterol in traditional Trobriand Islanders: the Kitava Study. Scandinavian journal of clinical and laboratory investigation. vol 63. issue 3. 2004-01-28. PMID:12817903. |
to analyse variables explaining the variation between serum triglycerides (tgs) and high density lipoprotein cholesterol (hdl-c) in a non-western population characterized by unfavourable tg and hdl-c levels despite marked leanness, low blood pressure and low fasting serum insulin. |
2004-01-28 |
2023-08-12 |
human |
| Charles Couillard, Marie-Claude Vohl, James C Engert, Isabelle Lemieux, Alain Houde, Natalie Almeras, Denis Prud'homme, Andre Nadeau, Jean-Pierre Despres, Jean Bergero. Effect of apoC-III gene polymorphisms on the lipoprotein-lipid profile of viscerally obese men. Journal of lipid research. vol 44. issue 5. 2004-01-23. PMID:12588953. |
whereas the apolipoprotein (apo) c-iii c3238g gene variant, often referred to as the ssti polymorphism, has been related to variations in plasma tg concentrations, another variation within the insulin responsive element (c-482t) of the apoc-iii gene has been associated with greater glucose and insulin responses to an oral glucose tolerance test (ogtt); however, these results were obtained in nonobese individuals. |
2004-01-23 |
2023-08-12 |
human |
| Julian B Mars. Lipoprotein metabolism in obesity and diabetes: insights from stable isotope kinetic studies in humans. Nutrition reviews. vol 61. issue 11. 2004-01-06. PMID:14677571. |
the paradigm of obesity leading to insulin resistance and type 2 diabetes is examined in relation to dyslipidemia, which typically consists of high levels of triglycerides (tg) and low levels of high-density lipoprotein (hdl). |
2004-01-06 |
2023-08-12 |
Not clear |
| Chatchalit Rattarasarn, Rattana Leelawattana, Supamai Soonthornpun, Worawong Setasuban, Atchara Thamprasit, Apiradee Lim, Wannee Chayanunnukul, Natawan Thamkumpee, Thavorn Daendumrongsu. Regional abdominal fat distribution in lean and obese Thai type 2 diabetic women: relationships with insulin sensitivity and cardiovascular risk factors. Metabolism: clinical and experimental. vol 52. issue 11. 2003-12-12. PMID:14624404. |
in contrast, tbf was correlated with fasting insulin (r=0.517; p=.023), area under the curve (auc) of insulin (r=0.625; p=.004), triglyceride (tg) (r=0.668; p=.002), and uric acid (r=0.49; p=.033). |
2003-12-12 |
2023-08-12 |
human |
| Junji Kamon, Toshimasa Yamauchi, Yasuo Terauchi, Naoto Kubota, Takashi Kadowak. [The mechanisms by which PPARgamma and adiponectin regulate glucose and lipid metabolism]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 122. issue 4. 2003-12-09. PMID:14501164. |
these alterations led to reduction of tissue tg content in muscle/liver, thereby ameliorating insulin resistance. |
2003-12-09 |
2023-08-12 |
mouse |
| Junji Kamon, Toshimasa Yamauchi, Yasuo Terauchi, Naoto Kubota, Takashi Kadowak. [The mechanisms by which PPARgamma and adiponectin regulate glucose and lipid metabolism]. Nihon yakurigaku zasshi. Folia pharmacologica Japonica. vol 122. issue 4. 2003-12-09. PMID:14501164. |
in muscle, adiponectin activated amp kinase and ppargamma pathways, thereby increasing beta-oxidation of lipids, leading to decreased tg content, which ameliorated muscle insulin resistance. |
2003-12-09 |
2023-08-12 |
mouse |
| Clinton R Bruce, Mitchell J Anderson, Andrew L Carey, David G Newman, Arend Bonen, Adamandia D Kriketos, Gregory J Cooney, John A Hawle. Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602787. |
we determined whole-body insulin sensitivity, long-chain fatty acyl coenzyme a (lcacoa) content, skeletal muscle triglyceride (tg(m)) concentration, fatty acid transporter protein content, and oxidative enzyme activity in eight patients with type 2 diabetes (type 2); six healthy control subjects matched for age (old), body mass index, percentage of body fat, and maximum pulmonary o(2) uptake; nine well-trained athletes (trained); and four age-matched controls (young). |
2003-12-09 |
2023-08-12 |
human |
| Clinton R Bruce, Mitchell J Anderson, Andrew L Carey, David G Newman, Arend Bonen, Adamandia D Kriketos, Gregory J Cooney, John A Hawle. Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602787. |
oxidative enzyme activities, fatty acid transporters (fat/cd36 and fabppm), and tg(m) were measured from basal muscle samples, and total lcacoa content was determined before and after insulin stimulation. |
2003-12-09 |
2023-08-12 |
human |
| Clinton R Bruce, Mitchell J Anderson, Andrew L Carey, David G Newman, Arend Bonen, Adamandia D Kriketos, Gregory J Cooney, John A Hawle. Muscle oxidative capacity is a better predictor of insulin sensitivity than lipid status. The Journal of clinical endocrinology and metabolism. vol 88. issue 11. 2003-12-09. PMID:14602787. |
furthermore, skeletal muscle oxidative capacity was a better predictor of insulin sensitivity than either tg(m) concentration or long-chain fatty acyl coa content. |
2003-12-09 |
2023-08-12 |
human |
| O Seda, L Kazdová, D Krenová, V Kre. Rosiglitazone improves insulin resistance, lipid profile and promotes adiposity in a genetic model of metabolic syndrome X. Folia biologica. vol 48. issue 6. 2003-11-10. PMID:12512799. |
in this study we show that 14-day rsg administration in a new rodent model of metabolic syndrome x, polydactylous rat strain (pd/cub), substantially improves its lipid profile (serum tgs 4.20 +/- 0.23 vs 2.34 +/- 0.14 mmol/l, p < 0.0001; ffa 0.46 +/- 0.05 vs 0.33 +/- 0.02 mmol/l, p = 0.017), diminishes the liver tg depots (15.76 +/- 0.60 vs 8.44 +/- 0.55 micromol/g, p < 0.0001), serum insulin concentrations (1.10 +/- 0.08 vs 0.63 +/- 0.02 nmol/l, p < 0.0001) and promotes visceral adiposity (adiposity index 1.28 +/- 0.03 vs 1.85 +/- 0.07, p < 0.0001). |
2003-11-10 |
2023-08-12 |
rat |
| Akira Katsuki, Yasuhiro Sumida, Hideki Urakawa, Esteban C Gabazza, Shuichi Murashima, Noriko Maruyama, Kohei Morioka, Kaname Nakatani, Yutaka Yano, Yukihiko Adach. Increased visceral fat and serum levels of triglyceride are associated with insulin resistance in Japanese metabolically obese, normal weight subjects with normal glucose tolerance. Diabetes care. vol 26. issue 8. 2003-11-04. PMID:12882859. |
the purpose of this study was to investigate the association between visceral adiposity or triglyceride (tg) metabolism and insulin resistance in metabolically obese, normal weight (monw) japanese individuals with normal glucose tolerance. |
2003-11-04 |
2023-08-12 |
human |
| Jukka T Kero, Eriika Savontaus, Maarit Mikola, Ullamari Pesonen, Markku Koulu, Ruth A Keri, John H Nilson, Matti Poutanen, Ilpo T Huhtaniem. Obesity in transgenic female mice with constitutively elevated luteinizing hormone secretion. American journal of physiology. Endocrinology and metabolism. vol 285. issue 4. 2003-10-30. PMID:12773309. |
serum leptin and insulin levels, and food intake, were also increased significantly in the tg females. |
2003-10-30 |
2023-08-12 |
mouse |
| Emperatriz Molero-Conejo, Luz Marina Morales, Virginia Fernández, Xiomara Raleigh, Maria Esther Gómez, Maritza Semprún-Fereira, Gilberto Campos, Elena Ryde. Lean adolescents with increased risk for metabolic syndrome. Archivos latinoamericanos de nutricion. vol 53. issue 1. 2003-10-27. PMID:12942870. |
biochemical measurements included fasting serum insulin, glucose, total cholesterol (tc), triglycerides (tg), hdl-c, ldl-c and vldl-c. homa insulin resistance (ir) and homa beta-cell function (beta-cell) were calculated. |
2003-10-27 |
2023-08-12 |
human |
| Emperatriz Molero-Conejo, Luz Marina Morales, Virginia Fernández, Xiomara Raleigh, Maria Esther Gómez, Maritza Semprún-Fereira, Gilberto Campos, Elena Ryde. Lean adolescents with increased risk for metabolic syndrome. Archivos latinoamericanos de nutricion. vol 53. issue 1. 2003-10-27. PMID:12942870. |
both boys and girls in the highest bmi quartile (bmi > 24 kg/m2) had significantly higher serum insulin, homa beta-cell, and tg levels, and the lowest hdl-c levels. |
2003-10-27 |
2023-08-12 |
human |
| C T Erel, L M Senturk, S Kaleli, A Gezer, B Baysal, E Tasa. Is serum leptin level regulated by thyroid functions, lipid metabolism and insulin resistance in polycystic ovary syndrome? Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology. vol 17. issue 3. 2003-10-17. PMID:12857430. |
fasting serum levels of thyroid stimulating hormone (tsh), free triiodothyronine (ft3), free thyroxine (ft4), fasting glucose, insulin, total cholesterol (tc), triglyceride (tg), high-density lipoprotein-cholesterol (hdl-c), low-density lipoprotein-cholesterol (ldl-c), very low-density lipoprotein-cholesterol (vldl-c) and leptin were measured and compared in the three groups and the correlations between serum levels of leptin and other parameters were evaluated. |
2003-10-17 |
2023-08-12 |
Not clear |
| Ana M Wägner, Jordi Ordóñez-Llanos, Rosa Arcelus, Rosa Bonet, Oscar Jorba, Jose L Sánchez-Quesada, Esther Alonso, Josep Julve, Antonio Pére. Postprandial lipidemia is normal in non-obese type 2 diabetic patients with relatively preserved insulin secretion. Metabolism: clinical and experimental. vol 52. issue 8. 2003-09-25. PMID:12898470. |
fasting low-density lipoprotein (ldl) cholesterol (ldlc), high-density lipoprotein (hdl) cholesterol (hdlc), free fatty acids, and apolipoprotein b (apob), and fasting and postprandial tg, retinylpalmitate (rp), ldl size, glucose, and insulin were measured. |
2003-09-25 |
2023-08-12 |
Not clear |
| Martin Muurling, Ronald P Mensink, Hanno Pijl, Johannes A Romijn, Louis M Havekes, Peter J Vosho. Rosiglitazone improves muscle insulin sensitivity, irrespective of increased triglyceride content, in ob/ob mice. Metabolism: clinical and experimental. vol 52. issue 8. 2003-09-25. PMID:12898477. |
rosiglitazone treatment resulted in significantly higher body weight and decreased plasma levels of glucose, insulin, and triglyceride (tg). |
2003-09-25 |
2023-08-12 |
mouse |