| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Martin Muurling, Miek C Jong, Ronald P Mensink, Gerard Hornstra, Vivian E H Dahlmans, Hanno Pijl, Peter J Voshol, Louis M Haveke. A low-fat diet has a higher potential than energy restriction to improve high-fat diet-induced insulin resistance in mice. Metabolism: clinical and experimental. vol 51. issue 6. 2002-07-18. PMID:12037721. |
in summary, our data show that lf diet has a higher potential than er to improve hf diet-induced insulin resistance, and that there is an association between improvement of insulin resistance and decrease of tg levels. |
2002-07-18 |
2023-08-12 |
mouse |
| Yutaka Nakaya, Noriko Ishimura, Eiko Takishita, Akira Takahash. Chronic feeding of a nitric oxide synthase inhibitor induces postprandial hypertriglyceridemia in type 2 diabetic model rats, Otsuka Long-Evans Tokushima Fatty rats, but not in nondiabetic rats. Metabolism: clinical and experimental. vol 51. issue 6. 2002-07-18. PMID:12037722. |
no detectable impairment of plasma levels of postprandial triglyceride (tg) or insulin sensitivity in nondiabetic rats was detected by chronic treatment of l-name, but significant impairment was observed in the cases of diabetic rats. |
2002-07-18 |
2023-08-12 |
rat |
| Molly T Kibenge, Catherine B Cha. The effects of high-fat diet on exercise-induced changes in metabolic parameters in Zucker fa/fa rats. Metabolism: clinical and experimental. vol 51. issue 6. 2002-07-18. PMID:12037723. |
in fa/fa rats fed the control diet, exercise reduced weight gain, caloric intake, and fasting plasma triglyceride (tg) concentrations without affecting fasting glucose and insulin concentrations. |
2002-07-18 |
2023-08-12 |
rat |
| Jennifer N Slawta, Jeffrey A McCubbin, Anthony R Wilcox, Susan D Fox, Darek J Nalle, Gail Anderso. Coronary heart disease risk between active and inactive women with multiple sclerosis. Medicine and science in sports and exercise. vol 34. issue 6. 2002-07-17. PMID:12048314. |
physical activity is strongly recommended as a principal component of coronary heart disease (chd) risk factor management aimed at favorably lowering abdominal fat accumulation, lowering levels of triglyceride (tg), raising levels of high-density lipoprotein-cholesterol (hdl-c), and improving insulin sensitivity. |
2002-07-17 |
2023-08-12 |
Not clear |
| Lijun Sun, Nabil Halaihel, Weiping Zhang, Thomas Rogers, Moshe Lev. Role of sterol regulatory element-binding protein 1 in regulation of renal lipid metabolism and glomerulosclerosis in diabetes mellitus. The Journal of biological chemistry. vol 277. issue 21. 2002-06-24. PMID:11875060. |
treatment of diabetic rats with insulin prevented the increased renal expression of srebp-1 and the accumulation of tg. |
2002-06-24 |
2023-08-12 |
mouse |
| Maria A Ostos, Delia Recalde, Nadine Baroukh, Ahinoa Callejo, Mustapha Rouis, Graciela Castro, Mario M Zaki. Fructose intake increases hyperlipidemia and modifies apolipoprotein expression in apolipoprotein AI-CIII-AIV transgenic mice. The Journal of nutrition. vol 132. issue 5. 2002-05-30. PMID:11983814. |
in tg mice, fructose intake increased triglycerides and cholesterol but did not induce insulin resistance. |
2002-05-30 |
2023-08-12 |
mouse |
| Laura L Atkinson, Sandra E Kelly, James C Russell, Jacob Bar-Tana, Gary D Lopaschu. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. vol 51. issue 5. 2002-05-23. PMID:11978655. |
intracellular triacylglycerol (tg) content of liver and skeletal muscle contributes to insulin resistance, and a significant correlation exists between tg content and the development of insulin resistance. |
2002-05-23 |
2023-08-12 |
rat |
| Laura L Atkinson, Sandra E Kelly, James C Russell, Jacob Bar-Tana, Gary D Lopaschu. MEDICA 16 inhibits hepatic acetyl-CoA carboxylase and reduces plasma triacylglycerol levels in insulin-resistant JCR: LA-cp rats. Diabetes. vol 51. issue 5. 2002-05-23. PMID:11978655. |
tg content, acc, and ampk were examined in the liver and skeletal muscle of insulin-resistant jcr:la-cp rats during the time frame when insulin resistance develops. |
2002-05-23 |
2023-08-12 |
rat |
| Shirya Rashid, Kristine D Uffelman, Gary F Lewi. The mechanism of HDL lowering in hypertriglyceridemic, insulin-resistant states. Journal of diabetes and its complications. vol 16. issue 1. 2002-05-20. PMID:11872362. |
the hypertriglyceridemia of insulin resistance is primarily due to an overproduction of very low-density lipoproteins (vldl), and in some instances, is also due to reduced vldl clearance and postprandial accumulation of vldl, chylomicrons, and their remnants [i.e., triglyceride (tg)-rich lipoproteins]. |
2002-05-20 |
2023-08-12 |
Not clear |
| R E Van Pelt, E M Evans, K B Schechtman, A A Ehsani, W M Kohr. Contributions of total and regional fat mass to risk for cardiovascular disease in older women. American journal of physiology. Endocrinology and metabolism. vol 282. issue 5. 2002-05-16. PMID:11934666. |
four primary markers of insulin resistance and dyslipidemia were assessed: 1) area under the curve for the insulin (ins(auc)) response to an oral glucose tolerance test (ogtt), 2) product of the ogtt glucose and insulin areas (ins(auc)xglu(auc)), 3) serum triglycerides (tg), and 4) high-density lipoprotein (hdl)-cholesterol. |
2002-05-16 |
2023-08-12 |
Not clear |
| Michelle Z Tucker, Lorraine P Turcott. Impaired fatty acid oxidation in muscle of aging rats perfused under basal conditions. American journal of physiology. Endocrinology and metabolism. vol 282. issue 5. 2002-05-16. PMID:11934676. |
these results indicate that, under euglycemic conditions in the presence of low insulin levels, the reduction in fa disposal to oxidation and the decrease in hsl content may contribute to the accumulation of tg in muscle of old animals. |
2002-05-16 |
2023-08-12 |
rat |
| Miguel Valle, Félix Gascón, Rosario Martos, Francisco Javier Ruz, Francisco Bermudo, Rosario Morales, Ramón Cañet. Metabolic cardiovascular syndrome in obese prepubertal children: the role of high fasting insulin levels. Metabolism: clinical and experimental. vol 51. issue 4. 2002-05-08. PMID:11912547. |
the obese children presented the following characteristics in comparison to the non-obese group: significantly high levels of insulin (8.2 +/- 0.52 v 6.12 +/- 0.34 microu/ml), triglycerides (tg) (0.79 +/- 0.04 v 0.60 +/- 0.02 mmol/l), uric acid (0.24 +/- 0.005 v 0.21 +/- 0.004 mmol/l), systolic (sbp) (94.59 +/- 1.06 v 88.85 +/- 1.2 mm hg) and diastolic (56.49 +/- 1.07 v 52.21 +/- 1.06 mm hg) blood pressure (dbp), and low levels of high-density lipoprotein cholesterol (hdl-c) (1.30 +/- 0.04 v 1.46 +/- 0.03 mmol/l), and nonesterified fatty acids (0.407 +/- 0.02 v 0.505 +/- 0.02 mmol/l). |
2002-05-08 |
2023-08-12 |
human |
| Sonia Vega-López, Karin Conde-Knape, Reyna-Luz Vidal-Quintanar, Neil S Shachter, Maria Luz Fernande. Sex and hormonal status influence the effects of psyllium on lipoprotein remodeling and composition. Metabolism: clinical and experimental. vol 51. issue 4. 2002-05-08. PMID:11912561. |
plasma levels of apo c iii, apo e, and insulin followed the same pattern as plasma tg with psy consumption and decreased by an average of 12% in men (p <.05), but increased by 10% in pmw (p <.05). |
2002-05-08 |
2023-08-12 |
Not clear |
| Sonia Vega-López, Karin Conde-Knape, Reyna-Luz Vidal-Quintanar, Neil S Shachter, Maria Luz Fernande. Sex and hormonal status influence the effects of psyllium on lipoprotein remodeling and composition. Metabolism: clinical and experimental. vol 51. issue 4. 2002-05-08. PMID:11912561. |
these reductions in apoproteins suggest an increased peripheral removal of tg in men, perhaps due to decreased insulin resistance, while in pmw, the increases in apoproteins may be related to an enhanced vldl production. |
2002-05-08 |
2023-08-12 |
Not clear |
| M E C Amaral, H C F Oliveira, E M Carneiro, V Delghingaro-Augusto, E C Vieira, J A Berti, A C Boscher. Plasma glucose regulation and insulin secretion in hypertriglyceridemic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 34. issue 1. 2002-04-30. PMID:11832997. |
in this study, we examined glucose homeostasis and insulin secretion in transgenic mice overexpressing the human apolipoprotein ciii gene (apo ciii tg). |
2002-04-30 |
2023-08-12 |
mouse |
| M E C Amaral, H C F Oliveira, E M Carneiro, V Delghingaro-Augusto, E C Vieira, J A Berti, A C Boscher. Plasma glucose regulation and insulin secretion in hypertriglyceridemic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 34. issue 1. 2002-04-30. PMID:11832997. |
old) apo ciii tg mice and the determination of insulin during the ipgtt were not different from those of control mice. |
2002-04-30 |
2023-08-12 |
mouse |
| M E C Amaral, H C F Oliveira, E M Carneiro, V Delghingaro-Augusto, E C Vieira, J A Berti, A C Boscher. Plasma glucose regulation and insulin secretion in hypertriglyceridemic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 34. issue 1. 2002-04-30. PMID:11832997. |
glucose (22.2 mmol/l) stimulated insulin secretion in isolated islets to the same extent in saline-treated control and apo ciii tg mice. |
2002-04-30 |
2023-08-12 |
mouse |
| M E C Amaral, H C F Oliveira, E M Carneiro, V Delghingaro-Augusto, E C Vieira, J A Berti, A C Boscher. Plasma glucose regulation and insulin secretion in hypertriglyceridemic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 34. issue 1. 2002-04-30. PMID:11832997. |
in islets from heparin-treated apo ciii tg mice, the insulin secretion at 2.8 and 22.2 mmol glucose/l was lower than in heparin-treated control mice. |
2002-04-30 |
2023-08-12 |
mouse |
| M E C Amaral, H C F Oliveira, E M Carneiro, V Delghingaro-Augusto, E C Vieira, J A Berti, A C Boscher. Plasma glucose regulation and insulin secretion in hypertriglyceridemic mice. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 34. issue 1. 2002-04-30. PMID:11832997. |
in conclusion, hypertriglyceridemia per se or a mild elevation in ffa did not affect insulin secretion or insulin resistance in adult or aged apo ciii tg mice. |
2002-04-30 |
2023-08-12 |
mouse |
| Pamela D Schoppee, James C Garmey, Johannes D Veldhui. Putative activation of the peroxisome proliferator-activated receptor gamma impairs androgen and enhances progesterone biosynthesis in primary cultures of porcine theca cells. Biology of reproduction. vol 66. issue 1. 2002-04-23. PMID:11751282. |
troglitazone (tg), a synthetic agonist of the peroxisome proliferator-activated receptor gamma (ppargamma) and a thiazolidinedione used to treat insulin resistance, decreases serum androgen concentrations in women with hyperthecosis and/or polycystic ovary syndrome. |
2002-04-23 |
2023-08-12 |
Not clear |