| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Ping Jiang, Ge-Hui Yuan, Bao-Rong Jiang, Jing-Yi Zhang, Yu-Qian Wang, Hui-Jie Lv, Zhan Zhang, Jia-Lin Wu, Qian Wu, Lei L. Effects of microplastics (MPs) and tributyltin (TBT) alone and in combination on bile acids and gut microbiota crosstalk in mice. Ecotoxicology and environmental safety. vol 220. 2021-06-30. PMID:34020283. |
in addition to decreasing triglyceride (tg) and increasing aspartate aminotransferase (ast) and macrophage-expressed gene 1 (mpeg1), 5mp induced hepatic cholestasis by stimulating the expression of the cholesterol hydroxylase enzymes cyp8b1 and cyp27a1, and inhibiting multidrug resistance-associated protein 2 and 3 (mrp2, mrp3), and bile-salt export pump (bsep) to prevent bile acids for entering the blood and bile. |
2021-06-30 |
2023-08-13 |
mouse |
| Ziye Zhu, Wenjun Zhou, Yang Yang, Kai Wang, Fenghua Li, Yanqi Dan. Quantitative Profiling of Oxylipin Reveals the Mechanism of Pien-Tze-Huang on Alcoholic Liver Disease. Evidence-based complementary and alternative medicine : eCAM. vol 2021. 2021-06-24. PMID:34158817. |
liver steatosis, triglyceride (tg), total cholesterol, serum alanine aminotransferase (alt), and aspartate aminotransferase (ast) levels were assayed. |
2021-06-24 |
2023-08-13 |
mouse |
| Ai-Jun Tong, Rong-Kang Hu, Lin-Xiu Wu, Xu-Cong Lv, Xin Li, Li-Na Zhao, Bin Li. Ganoderma polysaccharide and chitosan synergistically ameliorate lipid metabolic disorders and modulate gut microbiota composition in high fat diet-fed golden hamsters. Journal of food biochemistry. vol 44. issue 1. 2021-06-21. PMID:31793675. |
in the present study, we showed that ganoderma lucidum polysaccharide and chitosan (pc) significantly mitigated the hyperlipidemia in hfd-fed hamsters via lowering the contents of serum total triglyceride (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), and aspartate aminotransferase (ast). |
2021-06-21 |
2023-08-13 |
Not clear |
| Eda Dokumacioglu, Hatice Iskender, Arzu Sahin, Emine Yurdakul Erturk, Ozgur Kayna. Serum levels of nesfatin-1 and irisin in obese children. European cytokine network. vol 31. issue 1. 2021-06-17. PMID:32540807. |
serum nesfatin-1, irisin, sod, mda, fasting blood glucose, total cholesterol (tc), triglyceride (tg), hdl-c, ldl-c, aspartate amino transferase (ast), alanine amino transferase (alt)), blood urea nitrogen (bun), c-reactive protein (crp), calcium (ca), sodium (na), potassium (p), chromium (cr), ferritin, and vitamin b |
2021-06-17 |
2023-08-13 |
Not clear |
| Shuchun Wu, Xiaofeng Ji, Jianmei Wang, Huizhen Wu, Jianzhong Han, Hu Zhang, Jie Xu, Mingrong Qia. Fungicide bromuconazole has the potential to induce hepatotoxicity at the physiological, metabolomic and transcriptomic levels in rats. Environmental pollution (Barking, Essex : 1987). vol 280. 2021-05-31. PMID:33789219. |
it was observed that short time bromu exposure not only caused liver histological damage, including vacuolar degeneration of hepatocytes with pyknotic nuclei, but also changed the levels of some hepatic physiological parameters, including aspartate transaminase (ast), triglyceride (tg), pyruvate and total cholesterol (tc), indicating that bromu causes hepatotoxicity in rats. |
2021-05-31 |
2023-08-13 |
rat |
| Meng Zhao, Jianpin Qin, Wenting Shen, Aiping W. Bilobalide Enhances AMPK Activity to Improve Liver Injury and Metabolic Disorders in STZ-Induced Diabetes in Immature Rats via Regulating HMGB1/TLR4/NF- BioMed research international. vol 2021. 2021-05-31. PMID:33959665. |
we observed that bb improved the histopathological changes and maintained normal glucose metabolism, blood lipid, and liver function indicators, such as fasting blood glucose, obesity index, hba1c, homa-ir, fast serum insulin, adiponectin, total cholesterol (tc), triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), aspartate transaminase (ast), and alanine transaminase (alt) in stz-induced dm in immature rats by a biochemical analyzer or elisa. |
2021-05-31 |
2023-08-13 |
rat |
| Caiqi Du, Hong Wei, Min Zhang, Minghui Hu, Zhuoguang Li, Cai Zhang, Xiaoping Luo, Yan Lian. Genetic analysis and long-term treatment monitoring of 11 children with glycogen storage disease type IIIa. Journal of pediatric endocrinology & metabolism : JPEM. vol 33. issue 7. 2021-05-28. PMID:32623374. |
at the same time, alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), lactic acid and pyruvic acid in children were significantly decreased, while creatine kinase (ck) was significantly increased. |
2021-05-28 |
2023-08-13 |
Not clear |
| Yujun Liu, Yuan Gao, Fenglian Ma, Mengying Sun, Guangqing Mu, Yanfeng Tu. The ameliorative effect of Lactobacillus plantarum Y44 oral administration on inflammation and lipid metabolism in obese mice fed with a high fat diet. Food & function. vol 11. issue 6. 2021-05-25. PMID:32530448. |
oral administration of l. plantarum y44 regulated lipid metabolism disorder by inhibiting the expression of fatty acid synthase (fas) and acetyl-coa carboxylase (acc) in the liver of obese mice, reducing the contents of total cholesterol (tc), triacylglycerols (tg), low density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt), and aspartate transaminase (ast) and increasing the content of high-density lipoprotein cholesterol (hdl-c) in the serum of obese mice. |
2021-05-25 |
2023-08-13 |
mouse |
| Rui-Bo Jia, Zhao-Rong Li, Zhi-Rong Ou, Juan Wu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Physicochemical Characterization of Hizikia fusiforme Polysaccharide and Its Hypoglycemic Activity via Mediating Insulin-Stimulated Blood Glucose Utilization of Skeletal Muscle in Type 2 Diabetic Rats. Chemistry & biodiversity. vol 17. issue 10. 2021-05-17. PMID:32955163. |
hfp administration at 400 mg/kg body weight/day displayed greater advantages than metformin in controlling the levels of fasting blood glucose, triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast) and total bile acid (tba) of diabetic rats. |
2021-05-17 |
2023-08-13 |
rat |
| Renchao Dong, Xiaohui Wang, Lu Wang, Changyuan Wang, Kai Huang, Ting Fu, Kexin Liu, Jingjing Wu, Huijun Sun, Qiang Men. Yangonin inhibits ethanol-induced hepatocyte senescence via miR-194/FXR axis. European journal of pharmacology. vol 890. 2021-05-17. PMID:33068587. |
yan improved cell viabilities via cell count kit-8 (cck-8) methods and obviously reduced aspartate aminotransferase (ast), alanine aminotransferase (alt), total cholesterol (tc) and total triglyceride (tg) levels. |
2021-05-17 |
2023-08-13 |
Not clear |
| Y N Zhang, S Wang, Y Z Deng, X B Huang, K C Li, W Chen, D Ruan, W G Xia, S L Wang, C T Zhen. The application of reduced dietary crude protein levels supplemented with additional amino acids in laying ducks. Poultry science. vol 100. issue 4. 2021-05-14. PMID:33610902. |
the total protein content increased linearly (p < 0.05), tc content increased quadratically (p < 0.05), and contents of albumin, cre, tg, and phosphorus, and activities of aspartate aminotransferase and alt increased linearly and quadratically (both p < 0.05) with decreasing cp levels. |
2021-05-14 |
2023-08-13 |
Not clear |
| Hui-Fang Liu, Jian-Bo Huang, Min-Cong Huang, Tao Jiang, Gui-Yuan Lyu, Bo Li, Xin-Yu Qiu, Bin Cheng, Zhao-Huan Lo. [Study on anti-hyperlipidemia effect of Linderae Radix via regulating reverse cholesterol transport]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 7. 2021-05-14. PMID:33982484. |
serum total cholesterol(tc), triglyceride(tg), high density lipoprotein-cholesterol(hdl-c), low density lipoprotein-cholesterol(ldl-c), alanine aminotransferase(alt), and aspartate aminotransferase(ast) levels were measured by automatic blood biochemistry analyzer; the contents of tc, tg, total bile acid(tba) in liver and tc and tba in feces of rats were detected by enzyme colorimetry. |
2021-05-14 |
2023-08-13 |
rat |
| Yuyu Wang, Suming Xie, Zhijuan Nie, Quanjie Li, Yi Sun, Nailin Shao, Jiancao Gao, Jiawen Hu, Pao Xu, Gangchun X. Optimum feeding frequency of juvenile largemouth bass (Micropterus salmoides) reared in in-pond raceway recirculating culture system. Fish physiology and biochemistry. vol 46. issue 6. 2021-05-07. PMID:32865717. |
no significant differences were found in serum alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) activities, total protein (tp), lysozyme and triglyceride (tg) content, hepatic total antioxidant capacity (t-aoc), glutathione peroxidase (gsh-px) activities and malondialdehyde (mda) content among fish fed different feeding frequency (p > 0.05). |
2021-05-07 |
2023-08-13 |
cat |
| Ya Wu, Hailan Sun, Ruokun Yi, Fang Tan, Xin Zha. Anti-obesity effect of Liupao tea extract by modulating lipid metabolism and oxidative stress in high-fat-diet-induced obese mice. Journal of food science. vol 86. issue 1. 2021-05-03. PMID:33300164. |
lpt could also decrease the levels of alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (akp), total cholesterol (tc), triglycerides (tg), and low-density lipoprotein cholesterol (ldl-c) and increase the level of high-density lipoprotein cholesterol (hdl-c) in the liver. |
2021-05-03 |
2023-08-13 |
mouse |
| Ying Wang, Zishu Zeng, Lin Guan, Ran A. GRHL2 induces liver fibrosis and intestinal mucosal barrier dysfunction in non-alcoholic fatty liver disease via microRNA-200 and the MAPK pathway. Journal of cellular and molecular medicine. vol 24. issue 11. 2021-04-28. PMID:32324317. |
the inhibition of mir-200 and grhl2 or sirt1 overexpression lowered ha and ln in mouse liver tissue, occludin and zo-1 in mouse small intestine tissue, tnf-α and il-6 in mouse serum, glucose, total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast) and alanine aminotransferase (alt) in mouse serum, and also inhibited liver fibrosis and intestinal mucosal barrier dysfunction. |
2021-04-28 |
2023-08-13 |
mouse |
| Helda Tutunchi, Alireza Ostadrahimi, Maryam Saghafi-Asl, Mohammad-Javad Hosseinzadeh-Attar, Abolhasan Shakeri, Mohammad Asghari-Jafarabadi, Neda Roshanravan, Nazila Farrin, Mohammad Naemi, Milad Hasankhan. Oleoylethanolamide supplementation in obese patients newly diagnosed with non-alcoholic fatty liver disease: Effects on metabolic parameters, anthropometric indices, and expression of PPAR-α, UCP1, and UCP2 genes. Pharmacological research. vol 156. 2021-04-22. PMID:32217148. |
oea treatment significantly resulted in decreased serum levels of triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast), alt/ast, increased serum levels of high-density lipoprotein cholesterol (hdl-c), and improved appetite sensations. |
2021-04-22 |
2023-08-13 |
human |
| Weijia Yang, Minchun Yang, Hui Yao, Yelin Ma, Xuanxuan Ren, Long Teng, Tao Wan. Effects of shikonin from Zicao on high-fat diet-induced nonalcoholic fatty liver disease in rats. Pakistan journal of pharmaceutical sciences. vol 33. issue 6. 2021-04-19. PMID:33867326. |
our results showed that total cholesterol (tc), triacylglycerol (tg), low-density lipoprotein cholesterol, aspartate aminotransferase and alanine aminotransferase were significantly increased, while high-density lipoprotein cholesterol was decrease, accompanied by hepatic injury and lipid accumulation in hfd-fed rats. |
2021-04-19 |
2023-08-13 |
rat |
| Baran Ghezelbash, Nader Shahrokhi, Mohammad Khaksari, Firouz Ghaderi-Pakdel, Gholamreza Asadikara. Hepatoprotective effects of Shilajit on high fat-diet induced non-alcoholic fatty liver disease (NAFLD) in rats. Hormone molecular biology and clinical investigation. vol 41. issue 1. 2021-04-16. PMID:32083445. |
the serum levels of aspartate aminotransferase (ast), alanine aminotransferase (alt), triglycerides (tg), total cholesterol (tc), low-density lipoprotein (ldl), glucose and liver glutathione peroxidase (gpx), superoxide dismutase (sod) activity, malondialdehyde (mda) levels, liver weight, and histopathological manifestation outcomes were measured after the 2-week intervention. |
2021-04-16 |
2023-08-13 |
rat |
| X L Wu, X Y Zou, M Zhang, H Q Hu, X L Wei, M L Jin, H W Cheng, S Jian. Osteocalcin prevents insulin resistance, hepatic inflammation, and activates autophagy associated with high-fat diet-induced fatty liver hemorrhagic syndrome in aged laying hens. Poultry science. vol 100. issue 1. 2021-04-14. PMID:33357709. |
the plasma aspartate transaminase (ast), alkaline phosphatase (alp), total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), and high-density lipoprotein cholesterol (hdl-c) were measured using an automatic biochemistry analyzer. |
2021-04-14 |
2023-08-13 |
Not clear |
| Neda Haghighat, Morteza Zare, Nader Moein Vaziri, Babak Hosseini, Zahra Sohrabi, Hadi Bazyar, Meysam Alipour, Maryam Shafe. Serum cytokeratin 18 level is associated with dietary intake and serum triglycerides level in hemodialysis patients. Saudi journal of kidney diseases and transplantation : an official publication of the Saudi Center for Organ Transplantation, Saudi Arabia. vol 31. issue 2. 2021-04-06. PMID:32394907. |
an analysis of clinical characteristics, anthropometric indices, dietary intake, and lipid profile revealed a significant association between serum ck-18 and diabetes, metabolic syndrome, body mass index (bmi), triglyceride (tg), aspartate aminotransferase (ast), alanine aminotransferase (alt), energy intake (ei), protein intake (pi), and saturated fatty acid (sfa). |
2021-04-06 |
2023-08-13 |
Not clear |