| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Hong Zhang, Ting Liu, Cuiyun Li, Xiaojiao Li, Yanhua Din. Effect of moderate activity on liver function and serum lipid level in healthy subjects during the phase I clinical trial. Expert opinion on drug metabolism & toxicology. vol 16. issue 12. 2021-03-16. PMID:32915093. |
this study aims to investigate the incidence of aspartate aminotransferase (ast), alanine aminotransferase (alt) and triglyceride (tg) elevation, and the relationship with the phase i unit effect, and the moderate activity in healthy subjects enrolled in phase i clinical trials. |
2021-03-16 |
2023-08-13 |
human |
| C A L de Almeida, C K L de Almeida, E de Fátima Ferreira Martins, M Bessonart, R T Pereira, R R Paulino, P V Rosa, R Fortes-Silv. Coping with suboptimal water temperature: modifications in blood parameters, body composition, and postingestive-driven diet selection in Nile tilapia fed two vegetable oil blends. Animal : an international journal of animal bioscience. vol 15. issue 2. 2021-03-16. PMID:33573961. |
lin-20 showed lower very-low-density lipoprotein and cortisol, but higher high-density lipoprotein (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), and triglycerides (tg) than cor-20 (p < 0.05). |
2021-03-16 |
2023-08-13 |
Not clear |
| Da Eun Kim, Bo Yoon Chang, Byeong Min Jeon, Jong In Baek, Sun Chang Kim, Sung Yeon Ki. SGL 121 Attenuates Nonalcoholic Fatty Liver Disease through Adjusting Lipid Metabolism Through AMPK Signaling Pathway. International journal of molecular sciences. vol 21. issue 12. 2021-03-09. PMID:32630596. |
in nafld mice, sgl 121 significantly improved body fat mass; levels of hepatic triglyceride (tg), hepatic malondialdehyde (mda), serum total cholesterol (tc), high-density lipoprotein (hdl), and low-density lipoprotein (ldl); and activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast). |
2021-03-09 |
2023-08-13 |
mouse |
| Yu-Zhong DU, Jie Su, Mei-Qiu Yan, Su-Hong Chen, Gui-Yuan Lyu, Jing-Jing Y. [Improvement effect and mechanism of ethanol extract from Citri Reticulatae Pericarpium on triglyceride in hyperlipidemia model rat]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 46. issue 1. 2021-03-02. PMID:33645070. |
triglyceride(tg), alanine aminotransferase(alt), aspartate aminotransferase(ast), alkaline phosphatase(alp) in serum, tg in liver tissue and tg in fecal were detected. |
2021-03-02 |
2023-08-13 |
rat |
| Yun Ling, Zheng Shi, Xingliang Yang, Zhaowei Cai, Lixia Wang, Xuming Wu, Aiqin Ye, Jianping Jian. Hypolipidemic effect of pure total flavonoids from peel of Citrus (PTFC) on hamsters of hyperlipidemia and its potential mechanism. Experimental gerontology. vol 130. 2021-03-01. PMID:31760082. |
we found that ptfc significantly reduced levels of serum cholesterol (tc), triglyceride (tg) and low-density lipoprotein cholesterol (ldl-c) and improved levels of alanine transaminase (alt), aspartate transaminase (ast) and alkaline phosphatase (alp) which associated with liver function in golden hamsters. |
2021-03-01 |
2023-08-13 |
Not clear |
| Fatemeh Izadi, Amirhosein Farrokhzad, Babak Tamizifar, Mohammad Javad Tarrahi, Mohammad Hassan Entezar. Effect of sour tea supplementation on liver enzymes, lipid profile, blood pressure, and antioxidant status in patients with non-alcoholic fatty liver disease: A double-blind randomized controlled clinical trial. Phytotherapy research : PTR. vol 35. issue 1. 2021-02-23. PMID:32909326. |
after 8 weeks, sour tea administration significantly decreased serum triglyceride (tg) (p = .03), alanine aminotransferase (alt) (p = .01), and aspartate aminotransferase (ast) (p = .004) levels compared with the placebo. |
2021-02-23 |
2023-08-13 |
human |
| Lin Fan, Zhen Fu, Yan Xiong, Shaojun Ye, Yanfeng Wang, Guizhu Peng, Qifa Y. Double-lobectomy in a steatotic liver transplantation rat model. Experimental and therapeutic medicine. vol 21. issue 3. 2021-02-20. PMID:33603863. |
the results demonstrated that there were no significant differences in alanine aminotransaminase and aspartate aminotransferase levels between the scd and hfd groups (p>0.05), whereas the level of plasma triglyceride (tg) increased by 1.76-fold in the hfd group at week 2, and progressively decreased to baseline levels by week 8. |
2021-02-20 |
2023-08-13 |
rat |
| Noha A Beder, Nagwa I El-Kasrawy, Wael M Goda, Mervat A Abdel-Lati. Prognostic value of serum potassium level predicting the duration of recumbency in downer cows due to metabolic disorders. Tropical animal health and production. vol 52. issue 6. 2021-01-28. PMID:32954473. |
serum samples from 165 crossbred holstein dairy cows (105 downer cows of metabolic causes only and 50 healthy) and from 65 cured cows after treatment were used for analysis of calcium (ca), inorganic phosphorus (p), potassium (k), magnesium (mg), creatine phosphokinase (cpk), aspartate aminotransferase (ast), alanine aminotransferase (alt), gamma-glutamyl transferase (ggt), beta-hydroxybutyric acid (bhba), non-esterified fatty acid (nefa), and triglycerides (tg). |
2021-01-28 |
2023-08-13 |
Not clear |
| Satoshi Takeuchi, Yasuo Takahashi, Satoshi Asa. Comparison of pleiotropic effects of statins vs fibrates on laboratory parameters in patients with dyslipidemia: A retrospective cohort study. Medicine. vol 99. issue 50. 2021-01-04. PMID:33327270. |
generalized estimating equations were used to estimate the effects of the drugs on serum creatinine level, estimated glomerular filtration rate (egfr), urea nitrogen, hemoglobin a1c, aspartate aminotransferase, and alanine aminotransferase (alt), in addition to ldl cholesterol and tg levels, and red blood cell (rbc) and platelet (plt) counts, up to 12 months after the start of study drug administration.in tg-matched pairs, the increases in creatinine and urea nitrogen levels (p = .010 and p < .001, respectively) and the decreases in egfr, alt level and rbc count (p < .001, p = .003, and p = .014, respectively) were greater in fibrate users than in statin users. |
2021-01-04 |
2023-08-13 |
Not clear |
| Lin Wang, Wei-Hao Xia, Jun-Hong Wang, Rui-Feng Fan, Xu-Dong Niu, Yan-Ming Wang, Qing-Lei Li, Zhen-Yong Wang, Zhong-Hua Wan. Effects of beta-1,3-glucan supplementation on concentrations of serum metabolites in transition Holstein cows. Research in veterinary science. vol 132. 2020-12-31. PMID:32659488. |
blood samples were collected at day -21, 1, and 21 relative to calving for determination of serum triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), high density lipoprotein cholesterol (hdlc), very low density lipoprotein (vldl), glucose, insulin, β-hydroxybutyric acid (bhba), aspartate aminotransferase (ast), alanine aminotransferase (alt), glutamyl transpeptidase (ggt), and non-esterified fatty acid (nefa). |
2020-12-31 |
2023-08-13 |
Not clear |
| Rui-Bo Jia, Juan Wu, Zhao-Rong Li, Zhi-Rong Ou, Qiyuan Zhu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Comparison of physicochemical properties and antidiabetic effects of polysaccharides extracted from three seaweed species. International journal of biological macromolecules. vol 149. 2020-12-04. PMID:31945436. |
the analysis of body weight, water intake, fasting blood glucose, insulin, oral glucose tolerance, blood lipid indicators (including total cholesterol (tc), triglyceride (tg), low density lipoprotein cholesterol (ldl-c) and free fatty acid (ffa)), liver function indexes (involving alanine aminotransferase (alt) and aspartate aminotransferase (ast)) and renal function profiles (comprising uric acid (ua) and urea nitrogen (bun)) showed that aps possessed obvious antidiabetic activities, and fvp showed better effects in controlling the levels of ffa, ast, alt, ua and bun. |
2020-12-04 |
2023-08-13 |
rat |
| Chengxiao Wang, Luoyao Zheng, Shengnan Liu, Xiaoxi Guo, Yuan Qu, Mingju Gao, Xiuming Cui, Ye Yan. A novel acidic polysaccharide from the residue of Panax notoginseng and its hepatoprotective effect on alcoholic liver damage in mice. International journal of biological macromolecules. vol 149. 2020-12-04. PMID:32035151. |
after administration of pnps-0.5 m, the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), and hepatic malondialdehyde (mda) were reduced to normal. |
2020-12-04 |
2023-08-13 |
mouse |
| Rui-Bo Jia, Zhao-Rong Li, Juan Wu, Zhi-Rong Ou, Qiyuan Zhu, Baoguo Sun, Lianzhu Lin, Mouming Zha. Physicochemical properties of polysaccharide fractions from Sargassum fusiforme and their hypoglycemic and hypolipidemic activities in type 2 diabetic rats. International journal of biological macromolecules. vol 147. 2020-11-26. PMID:31899245. |
regarding to hypoglycemic and hypolipidemic effects, oral administration of sfps prominently restrained loss of body weight and increase of water intake, and also significantly controlled the increase of levels of fasting blood glucose, triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), uric acid (ua), urea nitrogen (bun), alanine aminotransferase (alt) and aspartate aminotransferase (ast) of diabetic rats, and sfp-2 showed better effects in controlling fasting blood glucose, alt, ua and bun levels. |
2020-11-26 |
2023-08-13 |
rat |
| Yanyan Zhao, Yunjun Yan, Liqiang Xie, Lixiao Wang, Yaojia He, Xiang Wan, Qingju Xu. Long-term environmental exposure to microcystins increases the risk of nonalcoholic fatty liver disease in humans: A combined fisher-based investigation and murine model study. Environment international. vol 138. 2020-11-20. PMID:32187572. |
the indices of aspartate aminotransferase (ast)/alanine aminotransferase (alt), triglyceride (tg), globulin (glb), and lactate dehydrogenase (ldh) had close positive associations with mc contamination, indicating that both liver damage and lipid metabolism dysfunction were induced by chronic mc exposure. |
2020-11-20 |
2023-08-13 |
mouse |
| Jia-Ling Guo, Wen-Ming Kuang, Yun-Fei Zhong, Yue-Lang Zhou, Yong-Jun Chen, Shi-Mei Li. Effects of supplemental dietary bile acids on growth, liver function and immunity of juvenile largemouth bass（Micropterus salmoides）fed high-starch diet. Fish & shellfish immunology. vol 97. 2020-11-09. PMID:31899355. |
the activities of alanine aminotransferase (alt), aspartate transaminase (ast), alkaline phosphatase (alp) and glucose contents in plasma of sb group were significantly lower than hs treatment, whereas the content of triglyceride (tg) and total cholesterol (tc) in plasma were significantly higher than hs treatment. |
2020-11-09 |
2023-08-13 |
cat |
| Yue-Lang Zhou, Jia-Ling Guo, Ren-Jun Tang, Hui-Jia Ma, Yong-Jun Chen, Shi-Mei Li. High dietary lipid level alters the growth, hepatic metabolism enzyme, and anti-oxidative capacity in juvenile largemouth bass Micropterus salmoides. Fish physiology and biochemistry. vol 46. issue 1. 2020-10-23. PMID:31522360. |
higher alanine aminotransferase (alt) and aspartate transaminase (ast) activities, total cholesterol (tc), triglyceride (tg), free fatty acids (ffa), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c) contents, and ldl-c/hdl-c value in plasma were recorded in fish fed 20% lipid diet, while higher insulin contents were obtained in fish fed 5% lipid diet. |
2020-10-23 |
2023-08-13 |
cat |
| Yin Ya. Ginsenosides reduce body weight and ameliorate hepatic steatosis in high fat diet‑induced obese mice via endoplasmic reticulum stress and p‑STAT3/STAT3 signaling. Molecular medicine reports. vol 21. issue 3. 2020-10-19. PMID:32016448. |
in addition, the levels of aspartate aminotransferase and alanine aminotransferase, triglyceride (tg), leptin and insulin in the serum were reduced compared with hfd mice. |
2020-10-19 |
2023-08-13 |
mouse |
| Weimin Li, Xiaoting Li, Maofeng Wang, Xuan Ge, Feixiang Li, Bian Huang, Jiren Peng, Guohong Li, Liang Lu, Zhuoyuan Yu, Jiaojiao Ma, Liaohang Xu, Meijuan Jin, Hongping Si, Rugen Wa. Association between red cell distribution width and the risk of heart events in patients with coronary artery disease. Experimental and therapeutic medicine. vol 9. issue 4. 2020-10-01. PMID:25780460. |
no statistically significant differences were observed between the groups with regard to the hematocrit, mean corpuscular volume, platelets, glucose, urea, albumin, aspartate aminotransferase, total cholesterol, triglycerides (tg), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol and n-terminal pro-brain natriuretic peptide (p>0.05). |
2020-10-01 |
2023-08-13 |
human |
| Yu-Feng Xing, Zhen Zhang, Wen-Jun Fu, Da-Qiao Zhou, Ailsa Chui-Ying Yuen, Daniel Kam-Wah Mok, Chi-On Chan, Guang-Dong Ton. Shugan Xiaozhi Decoction Attenuates Nonalcoholic Steatohepatitis by Enhancing PPAR Evidence-based complementary and alternative medicine : eCAM. vol 2016. 2020-10-01. PMID:28003852. |
compared with the model group, alanine aminotransferase (alt), aspartate aminotransferase (ast), free fatty acid (ffa), total cholesterol (tc), triacylglycerol (tg), and low-density lipoprotein cholesterol (ldl) serum in the serum were significantly reduced in all sx treatment groups in a dose-dependent manner. |
2020-10-01 |
2023-08-13 |
rat |
| Qiong-Hui Huang, Lie-Qiang Xu, Yu-Hong Liu, Jia-Zhen Wu, Xue Wu, Xiao-Ping Lai, Yu-Cui Li, Zi-Ren Su, Jian-Nan Chen, You-Liang Xi. Polydatin Protects Rat Liver against Ethanol-Induced Injury: Involvement of CYP2E1/ROS/Nrf2 and TLR4/NF-κB p65 Pathway. Evidence-based complementary and alternative medicine : eCAM. vol 2017. 2020-10-01. PMID:29250126. |
our results showed that pd pretreatment dramatically decreased the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), and lactate dehydrogenase (ldh) in the serum, suppressed the malonaldehyde (mda) and triglyceride (tg) content and the production of reactive oxygen species (ros), and enhanced the activities of superoxide dismutase (sod), glutathione peroxidase (gsh-px), catalase (cat), andalcohol dehydrogenase (adh), and aldehyde dehydrogenase (aldh), paralleled by an improvement of histopathology alterations. |
2020-10-01 |
2023-08-13 |
rat |