| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Junjie Wang, Baoyi Chen, Chaofan Cheng, Qingqing Wang, Lili Yang, Zeng Li, Xiongwen L. Timosaponin B II as a novel KEAP1-NRF2 inhibitor to alleviate alcoholic liver disease:Receptor structure-based virtual screening and biological evaluation. Chemico-biological interactions. 2025-01-25. PMID:39862944. |
results indicate that tbii significantly improved ethanol-induced liver injury, inhibited the elevation of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (t-cho), and triglycerides (tg) levels, and reduced lipid droplet accumulation in liver tissues. |
2025-01-25 |
2025-01-28 |
mouse |
| Niantong Xia, Hongwei Xue, Yihang Li, Jia Liu, Yang Lou, Shuyang Li, Yutian Wang, Juan Lu, Xi Che. Potential Mechanisms and Effects of Dai Bai Jie Ethanol Extract in Preventing Acute Alcoholic Liver Injury. Current issues in molecular biology. vol 47. issue 1. 2025-01-24. PMID:39852118. |
additionally, dbj-3 considerably decreased the serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), and triglyceride (tg) levels. |
2025-01-24 |
2025-01-27 |
mouse |
| Shuqin Lin, Yunjuan Xiao, Siyu Li, Liyan Tang, Haitao Shi, Meiling Hong, Li Din. Thiacloprid exposure disrupts the gut-liver axis and induces liver dysfunction in the Reeves' turtles (Mauremys reevesii). Ecotoxicology and environmental safety. vol 289. 2025-01-12. PMID:39799922. |
furthermore, elevated levels of liver function indicators, including aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), total bile acid (tba), and triglyceride (tg), were positively correlated with increased thi concentrations. |
2025-01-12 |
2025-01-16 |
Not clear |
| Jinliang Liang, Huanyi Liu, Guo Lv, Xiaotong Chen, Zhaoshou Yang, Kunhua Hu, Hongyan Su. Exploring the molecular mechanisms of tirzepatide in alleviating metabolic dysfunction-associated fatty liver in mice through integration of metabolomics, lipidomics, and proteomics. Lipids in health and disease. vol 24. issue 1. 2025-01-11. PMID:39794823. |
the results demonstrated that tirzepatide significantly reduced serum levels of alanine transaminase (alt) and aspartate transaminase (ast), as well as hepatic triglycerides (tg) and total cholesterol (tc), indicating its efficacy in treating mafld. |
2025-01-11 |
2025-01-14 |
mouse |
| Hai-Ying Tian, Dao-Jiang Yu, Teng Xie, Meng-Xia Xu, Yu-Hao Wang, Xi-Lu Sun, Xin-Meng Zhou, Ying-Xuan Han, Qing-Qing Liao, Yu-Jie Zhao, Juan Liao, Mohamed El-Kassas, Xiao-Dong Sun, Yuan-Yuan Zhan. Cordycepin alleviates metabolic dysfunction-associated liver disease by restoring mitochondrial homeostasis and reducing oxidative stress via Parkin-mediated mitophagy. Biochemical pharmacology. 2025-01-10. PMID:39793718. |
serum total cholesterol (tc), triacylglyceride (tg), and aspartate aminotransferase (ast) levels were measured. |
2025-01-10 |
2025-01-14 |
mouse |
| Qing Li, Min Fu, Shengqin Zhu, Juan Liu, Yanqing Li, Zhiyong Xue, Zhigang Zhou, Lijuan Y. Effects of dietary hydroxy-cinnamic acid derivatives on growth, muscle, and intestinal parameters of Tilapia (Oreochromis niloticus). Fish physiology and biochemistry. vol 51. issue 1. 2025-01-06. PMID:39760933. |
compared with the control group, the hydroxycinnamic acid derivatives group had significantly lower levels of aspartate aminotransferase (ast), glucose (glu), triglyceride (tg), and lactate dehydrogenase (ldh) (p < 0.05), but had significantly higher levels of albumin (alb), total protein (tp), alkaline phosphatase (alp), and blood urea nitrogen (bun) (p < 0.05). |
2025-01-06 |
2025-01-08 |
Not clear |
| Tao Cheng, Jiandong Chen, Beiping Tan, Shuyan Ch. Effects of α-lipoic acid (LA) supplementation in high-fat diet on the growth, glycolipid metabolism and liver health of largemouth bass (Micropterus salmoides). Fish & shellfish immunology. 2024-12-05. PMID:39637953. |
compared to the fish fed hf diet, fish fed hl diets showed lower serum total triglyceride (tg), alanine aminotransferase (alt), aspartate aminotransferase (ast), hepatic malondialdehyde (mda) and glycogen levels, and higher hepatic catalase (cat) and glutathione peroxidase (gsh-px) activities. |
2024-12-05 |
2024-12-08 |
cat |
| Amir Mosayyeb Zadeh, Seyyed Ali Mirghelenj, Mohsen Daneshyar, Mohsen Eslami, Mohammad Amir Karimi Torshizi, Mahdi Zhandi, Touba Nadri, John Patrick Kastelic, Peyman Hasanloo, Mehdi Nabilo. Dietary supplementation with 15% tomato pomace (Solanum lycopersicum L.) improves sperm production and antioxidant status in aged male broiler breeders. Poultry science. vol 104. issue 1. 2024-12-04. PMID:39631284. |
additionally, serum of t-15 roosters had lower cholesterol and triglyceride (tg) concentrations, along with decreased aspartate aminotransferase (ast) activity (p<0.05). |
2024-12-04 |
2024-12-07 |
Not clear |
| Ghazal Baghdadi, Farzad Shidfar, Marjan Mokhtare, Parvin Sarbakhsh, Shahram Aga. Effect of Pomegranate Peel Consumption on Liver Enzymes, Lipid Profile, Liver Steatosis, and Hs-CRP in Patients With Non-alcoholic Fatty Liver Disease: A Double-Blind, Placebo-Controlled, Randomized Clinical Trial. Phytotherapy research : PTR. 2024-11-28. PMID:39608758. |
at the end of the trial, pomegranate peel group had significantly higher reduction in tg (triglycerides), alt(alanine aminotransferase), ast(aspartate transferase), hs-crp and also had higher significant increase in hdl-c(high-density lipoprotein cholesterol) compared to the control group (p = 0/02, p = 0/02, p = 0/01, p = 0/01, and p = 0/04, respectively). |
2024-11-28 |
2024-12-01 |
Not clear |
| Jianxiu Zhang, Yilin Yuan, Xiaoyan Gao, Hui Li, Fengxia Yuan, Di Wu, Qinglong Cui, Guangchun Piao, Haidan Yua. Scopoletin ameliorates hyperlipidemia and hepatic steatosis via AMPK, Nrf2/HO-1 and NF-κB signaling pathways. Biochemical pharmacology. 2024-11-21. PMID:39571916. |
our results showed that ty injection significantly increased serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), interleukin-1β (il-1β), tumor necrosis factor-α (tnf-α), triglyceride (tg), total cholesterol (tc), low density lipoprotein (ldl-c) as well as malondialdehyde (mda) in the livers of the mice (p < 0.001, respectively), and decreased serum levels of high density lipoprotein (hdl-c), il-10 levels as well as superoxide dismutase (sod) in the livers (p < 0.001, respectively). |
2024-11-21 |
2024-11-24 |
mouse |
| Kai Wang, Lu Zhang, Hualiang Liang, Mingchun Ren, Haifeng Mi, Dongyu Huang, Jiaze G. Effects of Dietary Ferroporphyrin Supplementation on Growth Performance, Antioxidant Capacity, Immune Response, and Oxygen-Carrying Capacity in Gibel Carp ( Animals : an open access journal from MDPI. vol 14. issue 21. 2024-11-15. PMID:39518827. |
the addition of 0.03% and 0.04% fpr significantly increased alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels, respectively, while the glucose (glu), tc, and total triglyceride (tg) levels showed opposite trends. |
2024-11-15 |
2024-11-17 |
Not clear |
| Gailing Hao, Wenjin Geng, Chunzhen Li, Quanheng Li, Nan Zhang, Lian Jian. Critical risk factors analysis of infection-associated hemophagocytic lymphohistiocytosis in children. Annals of hematology. 2024-11-04. PMID:39495283. |
alanine aminotransferase (alt), aspartate aminotransferase (ast), lactate dehydrogenase (ldh), gamma-glutamyl transferase (ggt), d-dimer (dd), and triglycerides (tg) were significantly higher in the critical group, while albumin (alb) was significantly lower, showing statistical significance (p < 0.05). |
2024-11-04 |
2024-11-06 |
Not clear |
| Yalçın Burak Kara, Yahya Oze. Comparison of the Grades of Fatty Liver Disease With Perioperative Risk Factors in Patients With Laparoscopic Sleeve Gastrectomy. Cureus. vol 16. issue 9. 2024-10-21. PMID:39429298. |
biochemical markers were recorded, including alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol, triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), fasting blood glucose (fbg), hba1c, and vitamin d. the presence of type ii diabetes mellitus (t2dm) and hypertension (ht) was evaluated and compared with the grade of hepatosteatosis. |
2024-10-21 |
2024-10-23 |
Not clear |
| Gongming Zhu, Zhihui Liu, Hao Wang, Shaoyu Mou, Yuanyuan Li, Junguo Ma, Xiaoyu L. Risk Assessment of Fenpropathrin: Cause Hepatotoxicity and Nephrotoxicity in Common Carp ( International journal of molecular sciences. vol 25. issue 18. 2024-09-28. PMID:39337314. |
biochemical analyses results showed that fen exposure altered the levels of glucose (glu), total cholesterol (t-cho), triglyceride (tg), albumin (alb), alkaline phosphatase (alp), alanine transaminase (alt), and aspartate transaminase (ast) in carp serum, and caused histological injury of the liver and kidney, indicating that fen may cause hepatotoxicity and nephrotoxicity in carp. |
2024-09-28 |
2024-10-01 |
cat |
| Chen-Chen Jia, Rong Yue, Wen-Wen Xiang, Yi-Duo He, Xin Liu, Feng-Jie Wan. [Effect of Modified Xiaoyao Powder on intestinal barrier and intestinal flora in mice with metabolic associated fatty liver disease based on "gut-liver axis"]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 49. issue 16. 2024-09-22. PMID:39307786. |
serum aspartate aminotransferase(ast), alanine aminotransferase(alt), total cholesterol(tc), triacylglycerol(tg), low density lipoprotein cholesterol(ldl-c), high density lipoprotein cholesterol(hdl-c), and lipopolysaccharide(lps)levels were detected using the biochemical kits. |
2024-09-22 |
2024-09-26 |
mouse |
| Yao Le, Zhijun Wang, Qian Zhang, Ling Miao, Xiaohong Wang, Guorong Ha. Study on the mechanism of Shenling Baizhu powder on the pathogenesis of pregnancy complicated with non-alcoholic fatty liver, based on PI3K/AKT/mTOR signal pathway. European journal of histochemistry : EJH. vol 68. issue 3. 2024-09-17. PMID:39287141. |
maternal body weight, serum and liver levels of aspartate aminotransferase (ast), alanine transaminase (alt), triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), high density lipoprotein cholesterol (hdl-c), related inflammatory indexes interleukin-1 β (il-1 β), tumor necrosis factor-α (tnf-α) and interleukin-6 (il-6) were measured. |
2024-09-17 |
2024-09-20 |
rat |
| Bo Yang, Xiang Zhon. Clinical model to predict the risk of nonalcoholic fatty liver disease: A secondary analysis of data from a cross-sectional study. Medicine. vol 103. issue 36. 2024-09-10. PMID:39252286. |
significant differences were observed in terms of sex, body mass index (bmi), tobacco, hypertension, diabetes, alanine aminotransferase (alt), aspartate aminotransferase (ast), alt/ast ratio, uric acid (ua), fasting blood glucose (fbg), triglyceride (tg), high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, systolic blood pressure, and diastolic blood pressure (p < .05 for all comparisons). |
2024-09-10 |
2024-09-13 |
Not clear |
| Ya Huang, Tao Jin, Wenji Ni, Ying Zhou, Rui Zhang, Dandan Li, Yanhui Wan, Yonghui Shi, Xiaoping Hu, Yong Zhon. Baseline and change in serum lipid and uric acid level over time and incident of nonalcoholic fatty liver disease (NAFLD) in Chinese adults. Scientific reports. vol 14. issue 1. 2024-08-09. PMID:39122810. |
participants who developed nafld were older, male and had higher levels of body mass index (bmi), blood pressure, fasting blood glucose (fbg), triglyceride (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), free triiodothyronine (ft3), uric acid (ua), alanine aminotransferase (alt) and aspartate aminotransferase (ast); and lower levels of high-density lipoprotein cholesterol (hdl-c) and free thyroxine (ft4) (all p values < 0.05). |
2024-08-09 |
2024-08-13 |
human |
| Di Wu, Ze Fan, Xianhu Zheng, Jinnan Li, Meng Zhou, Haitao Zhang, Hong Xu, Shouqi Xie, Liansheng Wan. Evaluation of four novel non-grain protein sources completely replacing soybean meal on growth performance, serum biochemistry, amino acid transport and intestinal health of grass carp (Ctenopharyngodon idella) at different water temperatures. Fish & shellfish immunology. 2024-08-05. PMID:39102969. |
the alanine transaminase (alt), aspartate aminotransferase (ast), total protein (tp) and triglyceride (tg) concentrations of grass carp at 32°c were significantly lower than those at 24°c and 28°c (p < 0.001). |
2024-08-05 |
2024-08-08 |
Not clear |
| X Yan, K-J Mu, Q Wen, J Bian, D Yang, W-N Gao, W-M Zhan. Analyzing the impact of acupuncture in conjunction with a Quantum lipid-lowering device on hyperlipidemic rats: insights into adenosine monophosphate-activated protein kinase signaling, blood lipids, and gut microbiota. Journal of physiology and pharmacology : an official journal of the Polish Physiological Society. vol 75. issue 3. 2024-07-23. PMID:39042391. |
elisa results showed that compared with the model group, acup + quantum group could reduce the levels of total cholesterol (tc), triglycerides (tg), low-density lipoprotein-cholesterol (ldl-c), aspartate transaminase (ast) and aspartate transaminase (alt) in rats with hyperlipidemia (p<0.01), and increase the level of high-density lipoprotein-cholesterol (hdl-c) (p<0.01). |
2024-07-23 |
2024-07-25 |
rat |