| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Mohammadzadeh Saied, Kiani Ali, Amiri Mosaye. Rosemary (Rosmarinus officinalis L.) essential oil alleviates testis failure induced by Etoposide in male rats. Tissue & cell. vol 81. 2023-01-14. PMID:36640564. |
at the end of the experiment, rats were sacrificed by cervical dislocation, and blood samples were analyzed for serum alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), low-density lipoprotein-cholesterol (ldl-c), high-density lipoprotein-cholesterol (hdl-c), total cholesterol (tc), total protein (tp), glucose (glu) and testosterone. |
2023-01-14 |
2023-08-14 |
human |
| Xiaolei Yu, Xin Meng, Yidi Yan, Hui Wang, Lei Zhan. Extraction of Naringin from Pomelo and Its Therapeutic Potentials against Hyperlipidemia. Molecules (Basel, Switzerland). vol 27. issue 24. 2022-12-23. PMID:36558166. |
following the intragastric administration of naringin for 5 weeks, we measured the weight change, organ index, high-density lipoprotein cholesterol (hdl-c), serum total cholesterol (tc), serum triglycerides (tg), liver superoxide dismutase (sod), glutathione peroxidase (gsh-px), low-density lipoprotein cholesterol (ldl-c) level, malondialdehyde (mda), alanine aminotransferase (alt), and aspartate aminotransferase (ast) level of mice in the normal control and high-fat diet groups in addition to the high-, medium-, and low-dose naringin groups. |
2022-12-23 |
2023-08-14 |
mouse |
| Yu-Ru Li, Ya-Fang Zhao, Guo-Liang Cheng, En-Li Wang, Yu-Jun Tan, Jing-Chun Yao, Yan Zhao, Gui-Min Zhan. [Therapeutic effect of Jingfang Granules on CCl_4-induced liver fibrosis in mice and its mechanism]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 22. 2022-12-06. PMID:36471937. |
the levels of alanine aminotransferase(alt), aspartate aminotransferase(ast), total bile acid(tba), and triglyceride(tg) in the serum of mice were detected by an automated analyzer. |
2022-12-06 |
2023-08-14 |
mouse |
| Flavia Urbano, Mariangela Chiarito, Crescenza Lattanzio, Angela Messa, Marco Ferrante, Mariantonietta Francavilla, Irsida Mehmeti, Giuseppe Lassandro, Paola Giordano, Maria Felicia Faienz. Sex Hormone-Binding Globulin (SHBG) Reduction: The Alarm Bell for the Risk of Non-Alcoholic Fatty Liver Disease in Adolescents with Polycystic Ovary Syndrome. Children (Basel, Switzerland). vol 9. issue 11. 2022-11-24. PMID:36421197. |
thirty-two girls were assessed for anthropometric and biochemical markers: total cholesterol (tc), high density lipoprotein cholesterol (hdl-c), low density lipoprotein cholesterol (ldl-c), triglycerides (tg), glucose, insulin, alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma glutamyl transpeptidase (γgt). |
2022-11-24 |
2023-08-14 |
human |
| Hany Ezzat Khalil, Miada F Abdelwahab, Hairul-Islam Mohamed Ibrahim, Khalid A AlYahya, Abdullah Abdulhamid Altaweel, Abdullah Jalal Alasoom, Hussein Ali Burshed, Marwan Mohamed Alshawush, Shaimaa Wa. Cichoriin, a Biocoumarin, Mitigates Oxidative Stress and Associated Adverse Dysfunctions on High-Fat Diet-Induced Obesity in Rats. Life (Basel, Switzerland). vol 12. issue 11. 2022-11-11. PMID:36362887. |
triglycerides (tg), total cholesterol (tc), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), alanine transaminase (alt), aspartate transaminase (ast), creatine kinase mb (ck-mb), urea, creatinine, the hepatic and renal malondialdehyde (mda) as well as reduced glutathione (gsh) levels were assessed. |
2022-11-11 |
2023-08-14 |
rat |
| Sang Ryong Kim, Hyo Jin Park, Un Ju Jun. Anti-adiposity and lipid-lowering effects of schisandrol A in diet-induced obese mice. Journal of food biochemistry. 2022-11-04. PMID:36332134. |
furthermore, sola upregulated adipose lpl mrna expression and decreased plasma free fatty acid (ffa), triglyceride (tg), apolipoprotein (apo) b, aspartate aminotransferase levels and tg/hdl-cholesterol and apob/apoa1 ratios as well as hepatic lipid droplets. |
2022-11-04 |
2023-08-14 |
mouse |
| Rong Xie, Shaodong Chen, Fang Li, Liu Yang, Bangliang Y. Pirfenidone attenuates nonalcoholic fatty liver disease through activation of the nuclear factor erythroid 2-related factor 2 (Nrf2) signaling pathway. Journal of biochemical and molecular toxicology. 2022-11-02. PMID:36321572. |
the present study will evaluate the effects of pirfenidone on liver injury in high-fat diet (hfd)-fed mice to evaluate the value of pirfenidone in treating nafld. the pathology of nafld was simulated by feeding mice with an hfd in the present study, followed by treating the hfd mice with 150 and 300 mg/kg/day pirfenidone once a day. the pathological state of hfd mice was identified by the elevated liver weight, promoted serum triglyceride (tg), total cholesterol (tc), and low-density lipoprotein cholesterol (ldl-c) levels, declined serum high-density lipoprotein cholesterol (hdl-c) levels, increased alanine aminotransferase and aspartate aminotransferase activity, and histopathological changes to the liver tissues, all of which were dramatically ameliorated by 150 and 300 mg/kg pirfenidone administration. |
2022-11-02 |
2023-08-14 |
mouse |
| Hsiao-Yun Chang, Jiun-Rong Chen, Yi-Hsiu Chen, Qian Xiao, Ya-Ling Chen, Suh-Ching Yan. The Preliminary Results for Evaluating Cocoa Butter's Hepatoprotective Effects against Lipid Accumulation and Inflammation in Adult Male Rats Chronically Fed Ethanol. Bioengineering (Basel, Switzerland). vol 9. issue 10. 2022-10-27. PMID:36290494. |
after 8-week feeding, plasma aspartate aminotransferase (ast) and alanine aminotransferase (alt) activities, hepatic triglyceride (tg) levels, plasma intercellular adhesion molecular (icam)-1 levels, hepatic cytochrome p450 2e1 (cyp2e1) protein expression, and hepatic interleukin (il)-1β significantly increased in the e group compared to the c group. |
2022-10-27 |
2023-08-14 |
rat |
| Zahraa Alaaeldein Gadoa, Ahmed Hussein Moustafa, Samir Mohamed El Rayes, Ahmed A Arisha, Mohamed Fouad Mansou. Zinc Oxide Nanoparticles and Synthesized Pyrazolopyrimidine Alleviate Diabetic Effects in Rats Induced by Type II Diabetes. ACS omega. vol 7. issue 41. 2022-10-24. PMID:36278044. |
the results indicated that serum glucose, total cholesterol (tc), triacylglycerol (tg), low-density lipoprotein-cholesterol (ldl-c), very low-density lipoprotein-cholesterol (vldl-c), malondialdehyde, alanine aminotransferase (alt), aspartate aminotransferase (ast), and peroxisome proliferator-activated receptor gamma coactivator 1-alpha pgc-1α mrna expressions were increased in the diabetic group versus the control group, while serum insulin, high-density lipoprotein-cholesterol (hdl-c), superoxide dismutase (sod), and carnitine palmitoyltransferase 1a (cpt1a) mrna expression levels were decreased. |
2022-10-24 |
2023-08-14 |
rat |
| Mahsa Rastegar Moghaddam Poorbagher, Ehsan Karimi, Ehsan Oskoueia. Hepatoprotective effect of nanoniosome loaded Myristica fragrans phenolic compounds in mice-induced hepatotoxicity. Journal of cellular and molecular medicine. 2022-10-13. PMID:36226354. |
in addition, the blood levels of triglyceride (tg), cholesterol (chol), liver enzymes (aspartate aminotransferase (ast), alanine transaminase (alt), alkaline phosphatase (alp)) and total bilirubin were significantly (p ≤ 0.05) decreased. |
2022-10-13 |
2023-08-14 |
mouse |
| Hongkun Xue, Yu Wang, Hongwei Xiang, Qi Song, Guowei Zhang, Jianguo Wang, Shaoqin G. Exploring the Protective Effects and Mechanism of Huaji Jianpi Decoction against Nonalcoholic Fatty Liver Disease by Network Pharmacology and Experimental Validation. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-10-06. PMID:36199550. |
compared with the model group, the liver wet weight, liver/body ratio, the levels of total cholesterol (tc), triglyceride (tg), aspartate aminotransferase (ast), alanine aminotransferase (alt), and high-density lipoprotein (hdl) in serum in the hjjpd low-dose (17.52 g/kg·d), medium-dose (35.04 g/kg·d), and high-dose (70.07 g/kg·d) groups significantly decreased ( |
2022-10-06 |
2023-08-14 |
mouse |
| Bo Zhang, Zeben Wang, Chenxuan Huang, Dehe Wang, Dongmei Chang, Xiaowei Shi, Yifan Chen, Hui Che. Positive effects of Mulberry leaf extract on egg quality, lipid metabolism, serum biochemistry, and antioxidant indices of laying hens. Frontiers in veterinary science. vol 9. 2022-10-03. PMID:36187805. |
hens were fed a basal diet supplemented with 0 (control diet), 0.4, 0.8, or 1.2% mle for 56 d. results showed that the addition of 0.4-1.2% mle to the diet improved aspartate transaminase (ast) activity in the serum of laying hens, reduced low-density lipoprotein (ldl-c) content in the serum, and significantly decreased yolk triglyceride (tg) and total cholesterol (tc) contents ( |
2022-10-03 |
2023-08-14 |
Not clear |
| Fei Teng, Xiang-Wei Li, Min Li, Dong-Dong Fan, Jing-Jing Zhu, Hui-Min Gao, Zhi-Min Wan. [Components and lipid-lowering effect of total saponins from underground part of Gynostemma pentaphyllum]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 47. issue 18. 2022-09-27. PMID:36164912. |
furthermore, the levels of tc, tg, low-density lipoprotein cholesterol(ldl-c), high-density lipoprotein cholesterol(hdl-c), alanine transaminase(alt), aspartate transaminase(ast), bilirubin, and total bile acids in serum, as well as the levels of superoxide dismutase(sod), malondialdehyde(mda), peroxidase proliferator-activated receptor(ppar-γ) in the liver tissue, were determined. |
2022-09-27 |
2023-08-14 |
rat |
| Xin Jin, Yunshan Jiang, Jiongjiong Tan. Ultrasound-Guided Percutaneous Transhepatic Gallbladder Drainage Improves the Prognosis of Patients with Severe Acute Cholecystitis. Evidence-based complementary and alternative medicine : eCAM. vol 2022. 2022-09-08. PMID:36072405. |
before treatment and on days 1, 3, 5, and 7 after treatment, their serum levels of alanine aminotransferase (alt), alkaline phosphatase (alp), aspartate aminotransferase (ast), total bilirubin (tbil), triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), white blood cell count (wbc), il-2, il-4, il-6, il-8, and cancer antigen 19-9 (ca19-9) were measured. |
2022-09-08 |
2023-08-14 |
Not clear |
| Saied Mohammadzadeh, Ali Kiani, Mosayeb Amir. Lycopene modulates hepatic toxicity and testis injury induced by etoposide in male rats. F&S science. 2022-08-08. PMID:35940575. |
at the end of the experiment, rats were sacrificed by cervical dislocation, and blood samples were harvested and analyzed for serum alkaline phosphatase (alp), alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), low-density lipoprotein-cholesterol (ldl-c), high-density lipoprotein-cholesterol (hdl-c), total cholesterol (tc), total protein (tp), glucose (glu) and testosterone. |
2022-08-08 |
2023-08-14 |
rat |
| Ling-Cui Meng, Jia-Yi Zheng, Yu-Hui Qiu, Li Zheng, Jue-Yan Zheng, Yu-Qing Liu, Xiao-Lu Miao, Xin-Yi L. Salvianolic acid B ameliorates non-alcoholic fatty liver disease by inhibiting hepatic lipid accumulation and NLRP3 inflammasome in ob/ob mice. International immunopharmacology. vol 111. 2022-08-06. PMID:35932615. |
the results showed that salb significantly reduced the body weights and liver weights, and ameliorated plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), hepatic free fatty acid (ffa), total cholesterol (tc) levels, and hepatic tg and tc levels in ob/ob mice. |
2022-08-06 |
2023-08-14 |
mouse |
| Zhifu Cui, Ningning Jin, Felix Kwame Amevor, Gang Shu, Xiaxia Du, Xincheng Kang, Zifan Ning, Xun Deng, Yaofu Tian, Qing Zhu, Yan Wang, Diyan Li, Yao Zhang, Xiaoqi Wang, Xue Han, Jing Feng, Xiaoling Zha. Dietary supplementation of salidroside alleviates liver lipid metabolism disorder and inflammatory response to promote hepatocyte regeneration via PI3K/AKT/Gsk3-β pathway. Poultry science. vol 101. issue 9. 2022-08-04. PMID:35926351. |
in addition, high-fat diet-induced flhs hens had high levels of serum total cholesterol (tc), triglyceride (tg), alanine transaminase (alt), and aspartate aminotransferase (ast) compared to the con group, however, in the model+sds group, the levels of tc, tg, alt, and ast decreased significantly, whereas the level of superoxide dismutase (sod) increased significantly (p < 0.05). |
2022-08-04 |
2023-08-14 |
chicken |
| Xueqin Wang, Huahua Yu, Ronge Xing, Pengcheng L. Hepatoprotective Effect of Oyster Peptide on Alcohol-Induced Liver Disease in Mice. International journal of molecular sciences. vol 23. issue 15. 2022-07-28. PMID:35897657. |
the results demonstrate that ethanol administration could increase the activities of aspartate aminotransferase (ast), alanine transaminase (alt), γ-glutamyl transferase (ggt), reactive oxygen species (ros), malondialdehyde (mda), and triglycerides (tg), as well as increase the interleukin-1β (il-1β), interleukin-6 (il-6), and tumor necrosis factor (tnf-α) levels ( |
2022-07-28 |
2023-08-14 |
mouse |
| Yahui Zhang, Xiuying Tan, Yuan Cao, Xin An, Jihua Chen, Lina Yan. Punicalagin Protects against Diabetic Liver Injury by Upregulating Mitophagy and Antioxidant Enzyme Activities. Nutrients. vol 14. issue 14. 2022-07-27. PMID:35889739. |
simultaneously, the levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), free fatty acids (ffa), malondialdehyde (mda), and total superoxide dismutase (t-sod) in the serum and liver were significantly decreased, with reductions in fat lesions and inflammatory cells. |
2022-07-27 |
2023-08-14 |
mouse |
| Ying Lan, Chi Wang, Cheng Zhang, Pengju Li, Jinding Zhang, Hong Ji, Haibo Y. Dietary sea buckthorn polysaccharide reduced lipid accumulation, alleviated inflammation and oxidative stress, and normalized imbalance of intestinal microbiota that was induced by high-fat diet in zebrafish Danio rerio. Fish physiology and biochemistry. 2022-07-25. PMID:35879492. |
results showed that adding 2 and 4 g/kg of sp in the hfd significantly improved the survival rate of zebrafish; reduced the levels of serum triglyceride (tg), total cholesterol (tc), aspartate aminotransferase (ast), and alanine transaminase (alt); and alleviated the lipid accumulation in the liver of zebrafish. |
2022-07-25 |
2023-08-14 |
zebrafish |