| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tomoya Shirakawa, Julius Fink, Zen-U Hotta, Yosuke Shimada, Yan Lu, Junhua Du, Kazuhito Matsushita, Satoshi Hori, Hisamitsu Ide, Shigeo Hori. The impact of serum testosterone level to reflect age-related multi-organ functions. Endocrine journal. 2024-01-08. PMID:38191198. |
a multiple regression analysis was conducted to determine whether biomarkers including hemoglobin (hb), hematocrit (hct), luteinizing hormone (lh), follicle stimulating hormone (fsh), alkaline phosphatase (alp), albumin (alb), creatinine (cre), aspartate aminotransferase (ast), alanine aminotransferase (alt), glucose (glu), c-reactive protein (crp), triglycerides (tg), high-density lipoprotein cholesterol (hdl-c), and low-density lipoprotein cholesterol (ldl-c) values were associated with serum total testosterone concentration. |
2024-01-08 |
2024-01-10 |
human |
| Jarawee Supanta, Janine L Brown, Pakkanut Bansiddhi, Chatchote Thitaram, Veerasak Punyapornwithaya, Khanittha Punturee, Nopphamas Somboon, Patcharapa Towiboon, Jaruwan Khonme. Physiological changes in captive elephants in Northern Thailand as a result of the COVID-19 tourism ban - muscle, liver, metabolic function, and body condition. Frontiers in veterinary science. vol 10. 2024-01-05. PMID:38179326. |
fifty-eight elephants from six tourist camps were assigned a body condition score (bcs) and blood samples were collected monthly for 2 years during the travel ban to measure: (1) muscle enzymes [creatine kinase (ck), aspartate aminotransferase (ast)]; (2) liver enzymes [aspartate aminotransferase (ast), alkaline phosphatase (alp), gamma-glutamyl transferase (ggt)]; (3) lipids [total cholesterol (tc), triglycerides (tg), low (ldl) and high (hdl) density lipoproteins]; and metabolic function [glucose, insulin, fructosamine]. |
2024-01-05 |
2024-01-07 |
Not clear |
| Ahmed Hjazi, Chou-Yi Hsu, Wafaa M Al-Attar, Yasir Qasim Almajidi, Beneen M Hussien, Abdullah Ali Alzahrani, A K Kareem, Adeeb Abdulally Abdulhussien Alazbjee, Xuan Men. The association of exposure to polychlorinated biphenyls with lipid profile and liver enzymes in umbilical cord blood samples. Chemosphere. 2024-01-04. PMID:38176591. |
lipid profile including low-density lipoprotein (ldl-c), total cholesterol (tc), triglycerides (tg), and high-density lipoprotein (hdl-c), as well as liver enzymes i.e., alanine amino transferase (alt), aspartate amino transferase (ast), γ-glutamyl-transferase (ggt) and alkaline phosphatase (alp) were determined from umbilical cord blood samples. |
2024-01-04 |
2024-01-07 |
Not clear |
| Su-Wen Chen, Guo-Liang Yin, Chao-Yuan Song, De-Cheng Meng, Wen-Fei Yu, Xin Zhang, Ya-Nan Feng, Peng-Peng Liang, Feng-Xia Zhan. [Diosgenin alleviates NAFLD induced by a high-fat diet in rats via mTOR/SREBP-1c/HSP60/MCAD/SCAD signaling pathway]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 48. issue 19. 2023-12-19. PMID:38114120. |
the levels of triglyceride(tg), total cholesterol(tc), alanine transaminase(alt), and aspartate transaminase(ast) in the serum were determined by the biochemical method. |
2023-12-19 |
2023-12-23 |
rat |
| Yali Tian, Hang Li, Dongying Zhang, Chen Wang, Ruijuan Hao, Xiaoying Ru, Qin Hu, Yang Huang, Chunhua Zh. Effect of marine heatwaves on juvenile greater amberjack (Seriola dumerili). Marine environmental research. vol 193. 2023-12-19. PMID:38113590. |
repeated mhws in which water temperatures were increased (24 °c to 28 °c and 32 °c) resulted in changes in enzyme activity levels (catalase (cat), superoxide dismutase (sod), and glutathione (gsh)), as well as the level of malondialdehyde (mda) for antioxidant defense, immune function (acid phosphatase (acp), alkaline phosphatase (alp), and lysozyme (lyz)), and energy metabolism (including triglycerides (tg), glucose (glu), aspartate aminotransferase (got), alanine aminotransferase (alt), lactate dehydrogenase (ldh), and succinate dehydrogenase (sdh)). |
2023-12-19 |
2023-12-23 |
cat |
| Ik-Rak Jung, Rexford S Ahima, Sangwon F Ki. Time-restricted feeding ameliorates MCDD-induced steatohepatitis in mice. bioRxiv : the preprint server for biology. 2023-11-28. PMID:38014152. |
here, we show that trf alleviated markers of nash, i.e., reduced hepatic steatosis, liver triglycerides (tg), serum alanine transaminase (alt) and aspartate aminotransferase (ast), inflammation and fibrosis in mcdd mice. |
2023-11-28 |
2023-11-29 |
mouse |
| Si Sun, Bingqing Li, Shuang Peng, Lian H. Protective Effect of Sea Buckthorn (Hipphophae Rhamnoides) Extract on Liver Injury Induced by High-Fat Diet in Mice. Studies in health technology and informatics. vol 308. 2023-11-26. PMID:38007790. |
in addition, the concentration of total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), alanine aminotransferase (alt), and aspartate aminotransferase (ast) in serum of mice was decreased by the intervention of sea buckthorn extract, whereas the concentration of high-density lipoprotein cholesterol (hdl-c) was increased. |
2023-11-26 |
2023-11-28 |
mouse |
| Lu Wang, Zixu Wang, Yaoxing Chen, Jing Ca. Effects of monochromatic light on hepatic glycogen and lipid synthesis in broilers. Poultry science. vol 103. issue 1. 2023-11-06. PMID:37931402. |
at p35, rl promoted the hepatic glycogen and tg contents by increasing gsk-3β, akt1, acc, and apob mrna levels, and the serum alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were increased than in the wl group. |
2023-11-06 |
2023-11-08 |
Not clear |
| Wei Wang, Jun Yan, Long Han, Zi-Lin Zou, Ai-Lei X. Silencing METTL14 alleviates liver injury in non-alcoholic fatty liver disease by regulating mitochondrial homeostasis. Biomolecules & biomedicine. 2023-10-30. PMID:37902450. |
subsequently, serum levels of liver function indices (aspartate aminotransferase [ast], alanine aminotransferase [alt], total cholesterol [tc], and triglycerides [tg]), inflammatory markers (tumor necrosis factor-alpha [tnf-α], interleukin [il]-6, and il-1β), and mitochondrial dysfunction indicators (fission 1 protein [fis1], dynamin-related protein 1 [drp1], mitofusin 2 [mfn2], sid1 transmembrane family member 2 [sidt2], and mitochondrial membrane potential [mmp]) in the liver and cells were evaluated. |
2023-10-30 |
2023-11-08 |
mouse |
| Hang Zhao, Hongyang Tia. Icariin alleviates high-fat diet-induced nonalcoholic fatty liver disease via up-regulating miR-206 to mediate NF-κB and MAPK pathways. Journal of biochemical and molecular toxicology. 2023-10-27. PMID:37888945. |
after ica treatment, the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total bilirubin (tbil), triglyceride (tg), total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c) and high-density lipoprotein cholesterol (hdl-c) were measured; liver injury and lipid deposition were observed by h&e and oil red o staining; interleukin-1β (il-1β), il-12, and il-6 were measured by enzyme-linked immunosorbent assay. |
2023-10-27 |
2023-11-08 |
rat |
| Selcen Çaki. Effect of Boric Acid on Metabolic Peptides and Some Biochemical Parameters in Experimental Diabetic Rats. Biological trace element research. 2023-10-23. PMID:37872360. |
serum asprosin, nesfatin-1, preptin, insulin, total cholesterol (tc), triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), aspartate transaminase (ast), alanine transaminase (alt), and glucose analyses were performed. |
2023-10-23 |
2023-11-08 |
rat |
| Xi Meng, Guoqi Yu, Tingyu Luo, Ruiyuan Zhang, Jun Zhang, Yongjie Li. Transcriptomics integrated with metabolomics reveals perfluorobutane sulfonate (PFBS) exposure effect during pregnancy and lactation on lipid metabolism in rat offspring. Chemosphere. 2023-09-11. PMID:37696479. |
although the biochemical index difference including total cholesterol (tc), triglyceride (tg), high-density lipoprotein (hdl), low-density lipoprotein (ldl), alanine amino transaminase (alt), aspartate amino transferase (ast), and fasting blood glucose between exposed groups and the control group was not significant, transcriptome analyses showed that the differentially expressed genes (degs) in the 50 mg/kg/day pfbs exposure group were significantly related to protein digestion and absorption, peroxisome proliferator activated-receptor (ppar) signaling pathway, xenobiotic metabolism by cytochrome p450, glycine, serine and threonine metabolism, β-alanine metabolism, bile secretion, unsaturated fatty acid (fa) biosynthesis, and alanine, aspartate and glutamate metabolism. |
2023-09-11 |
2023-10-07 |
rat |
| Metin Özaslan, Dilek Peke. Evaluation of Laboratory Follow-up in Acne Patients Treated With Isotretinoin. Cutis. vol 112. issue 1. 2023-08-23. PMID:37611311. |
patient demographic data; cumulative isotretinoin doses; alanin transaminase (alt), aspartate transaminase (ast), γ-glutamyltransferase (ggt), creatinine kinase (ck), low-density lipoprotein cholesterol (ldl-c), and triglyceride (tg) levels during treatment were recorded. |
2023-08-23 |
2023-09-07 |
Not clear |
| Esrafil Mansouri, Zeinab Shafiei Seifabadi, Nastaran Azarbarz, Maasoumeh Zare Moaied. Effects of sodium hydrosulfide (NaHS) on cisplatin-induced hepatic and cardiac toxicity. Drug and chemical toxicology. 2023-08-09. PMID:37553904. |
cp injection significantly increased alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), lactate dehydrogenase (ldh), creatine phospho kinase (ck-mb), cholesterol, low-density lipoprotein (ldl), triglyceride (tg), and lipid peroxidation levels, while high-density lipoprotein (hdl), albumin, glutathione peroxidase, superoxide dismutase, and catalase (cat) levels were significantly reduced with pathological alterations in liver and heart tissues. |
2023-08-09 |
2023-08-16 |
rat |
| Xiaoxu Wang, Bin Liu, Yanjun Liu, Yuliu Wang, Zhigao Wang, Yu Song, Jie Xu, Changhu Xu. Antioxidants ameliorate oxidative stress in alcoholic liver injury by modulating lipid metabolism and phospholipid homeostasis. Lipids. 2023-08-07. PMID:37547958. |
the in vivo results indicated that antioxidants ameliorated alcohol-induced changes in histopathology, reducing the levels of alcohol metabolizing factors and aspartate aminotransferase (ast), alanine aminotransferase (alt), triglyceride (tg), and total cholesterol (tc) contents, which demonstrated that antioxidants effectively mitigated liver injury in ald mice. |
2023-08-07 |
2023-08-14 |
mouse |
| Hui Guan, Guangrui Shao, Fang Cheng, Pingjuan Ni, Mei W. Risk factors of nonalcoholic fatty liver disease in healthy women. Medicine. vol 102. issue 31. 2023-08-06. PMID:37543765. |
their basic information and medical history [including age, height, weight, body mass index (bmi)], abdominal ultrasound results, and, serological indexes [including white blood cells, platelet count, fasting blood glucose, triglyceride (tg), total cholesterol, low-density lipoprotein cholesterol, high-density lipoprotein cholesterol (hdlc), uric acid (ua), alanine aminotransferase (alt), aspartate aminotransferase (ast), and glutamyl transpeptidase] were collected. |
2023-08-06 |
2023-08-14 |
Not clear |
| b' Fatih Mehmet G\\xc3\\xbcr, Sedat Bilgi\\xc3\\xa. Silymarin, an antioxidant flavonoid, protects the liver from the toxicity of the anticancer drug paclitaxel. Tissue & cell. vol 83. 2023-07-17. PMID:37459721.' |
pac also resulted in a significant increase in serum triglyceride (tg), cholesterol (ch), alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels compared with the control group. |
2023-07-17 |
2023-08-14 |
rat |
| Shuai Hao, Fannian Li, Qiancheng Li, Qi Yang, Wenjing Zhan. Phycocyanin Protects against High Glucose High Fat Diet Induced Diabetes in Mice and Participates in AKT and AMPK Signaling. Foods (Basel, Switzerland). vol 11. issue 20. 2023-07-11. PMID:37430932. |
meanwhile, phycocyanin also significantly decreased the diabetes-induced abnormal serum biomarker variations, including triglyceride (tg), total cholesterol (tc), aspartate transaminase (ast), and glutamic-pyruvic transaminase (alt), and increased the superoxide dismutase (sod) content. |
2023-07-11 |
2023-08-14 |
mouse |
| Fang Xiong, Chao Yu, Ling-Juan Zhu, Tao Wang, Wei Zhou, Hui-Hui Bao, Xiao-Shu Chen. [Associations Between Insulin Resistance Indexes and Hyperuricemia in Hypertensive Population]. Zhongguo yi xue ke xue yuan xue bao. Acta Academiae Medicinae Sinicae. vol 45. issue 3. 2023-07-05. PMID:37407524. |
results the 14 220 hypertension patients included 6 713 males and 7 507 females,with the average age of (63.8±9.4) years old,the average uric acid level of (418.9±120.6) mmol/l,and the hua detection rate of 44.4%.the hua group had higher proportions of males,current drinking,current smoking,diabetes,and using antihypertensive drugs,older age,higher diastolic blood pressure,wc,bmi,homocysteine,total cholesterol,tg,low-density lipoprotein cholesterol,blood urea nitrogen,creatinine,aspartate aminotransferase,alanine aminotransferase,total protein,albumin,total bilirubin,direct bilirubin, mets-ir, tyg, tyg-bmi, tyg-wc, vai, tg/hdl-c, and lap, and lower systolic blood pressure and hdl-c than the normal uric acid group (all |
2023-07-05 |
2023-08-14 |
Not clear |
| Jiangxue Han, Shunwang Li, Weizhi Wang, Xinhai Jiang, Chao Liu, Lijuan Lei, Yining Li, Ren Sheng, Yuyan Zhang, Yexiang Wu, Jing Zhang, Yuhao Zhang, Yanni Xu, Shuyi S. SIRT1 Activator E1231 Alleviates Nonalcoholic Fatty Liver Disease by Regulating Lipid Metabolism. Current issues in molecular biology. vol 45. issue 6. 2023-06-27. PMID:37367070. |
liver-related plasma biochemistry parameter tests, oil red o staining, and hematoxylin-eosin staining results showed that e1231 treatment ameliorated plasma dyslipidemia, plasma marker levels of liver damage (alanine aminotransferase (alt) and aspartate aminotransferase (ast)), liver total cholesterol (tc) and triglycerides (tg) contents, and obviously decreased hepatic steatosis score and nafld activity score (nas) in the nafld mouse model. |
2023-06-27 |
2023-08-14 |
mouse |