| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Li-Shan Zhou, Su-Qi Yan, Xiao-Li Xiong, Juan Huang, Huan Qin, Ling-Ling Zhang, Lin-Li Zhang, Jian-Qiao Tan. [Psoralen and isopsoralen improve lipid metabolism disorder via inhibition of NF-κB activation in LO2 cells]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica. vol 44. issue 10. 2019-09-12. PMID:31355570. |
intracellular triglyceride( tg) and total cholesterol( tc) content,the cell supernatant alanine aminotransferase( alt) and aspartate aminotransferase( ast) levels were determined by enzyme method. |
2019-09-12 |
2023-08-13 |
human |
| Tomasz Maciej Ciesielski, Christian Sonne, Ingunn Ormbostad, Jon Aars, Elisabeth Lie, Jenny Bytingsvik, Bjørn Munro Jensse. Effects of biometrics, location and persistent organic pollutants on blood clinical-chemical parameters in polar bears (Ursus maritimus) from Svalbard, Norway. Environmental research. vol 165. 2019-09-06. PMID:29860211. |
the aim was to study how age, body condition (bc), biometrics, plasma lipid content and geographical location may confound the relationship between persistent organic pollutants (pops) including pcbs, hcb, chlordanes, ddts, hchs, mirex and oh-pcbs and the concentrations of 12 specific bccps (hematocrit [hct], hemoglobin [hb], aspartate aminotransferase [asat], alanine aminotransferase [alat], γ-glutamyltransferase [ggt], creatine kinase [ck], triglycerides [tg], cholesterol [chol], high-density lipoprotein [hdl], creatinine (crea], urea, potassium (k]), and to investigate if any of these bccps may be applied as potential biomarkers for pop exposure in polar bears. |
2019-09-06 |
2023-08-13 |
Not clear |
| Xue-Yuan Jin, Chuan-Bao Zhu, Shi-Yong Fan, Jia-Lin Sun, Yu-Cong Shi, Chu-Han Wang, Hui-Fen Wang, Bo-Hua Zhong, Yi-Shan Yao, Wei-Guo Sh. Novel hypolipidemic conjugates of fatty acid and bile acid with lysine for linkage. Drug development and industrial pharmacy. vol 45. issue 6. 2019-09-02. PMID:30892088. |
conjugates of stearic acid with cholic acid and palmitic acid with ursodeoxycholic acid (at dosages of 50, 100, and 200 mg/kg) were further evaluated to determine their ability to reduce aspartate aminotransferase (ast), alanine aminotransferase (alt), tc, and tg levels in mice fed with hfd. |
2019-09-02 |
2023-08-13 |
mouse |
| Congjian Shi, Weiju Xue, Bowen Han, Fengli Yang, Yaping Yin, Chengmu H. Acetaminophen aggravates fat accumulation in NAFLD by inhibiting autophagy via the AMPK/mTOR pathway. European journal of pharmacology. vol 850. 2019-08-06. PMID:30753863. |
apap treatment significantly aggravated hepatic lipid accumulation, increased the serum levels of triglyceride (tg), alanine aminotransferase (alt) and aspartate aminotransferase (ast), and increased hepatic lipid accumulation in h&e and oil red o staining results. |
2019-08-06 |
2023-08-13 |
mouse |
| Bakheet Elsadek, El-Sayed El-Sayed, Ahmed Mansour, Ayman Elaza. Abrogation of carbon tetrachloride-induced hepatotoxicity in Sprague-Dawley rats by Ajwa date fruit extract through ameliorating oxidative stress and apoptosis. Pakistan journal of pharmaceutical sciences. vol 30. issue 6. 2019-07-29. PMID:29175788. |
like silymarin, ajwa date extract produced significant decrease in serum levels of alanine transaminase (alt), aspartate transaminase (ast), alkaline phosphatase (alp), total cholesterol, triglycerides (tg) and ldl-cholesterol as well as lipid peroxides measured as malondialdehyde (mda), hydroxyproline and caspase-3 contents of liver tissue with marked increase in serum albumin, hdl-cholesterol and reduced glutathione (gsh) content as well as enzyme activities of super oxide dismutase (sod), catalase (cat) and glutathione-s-transferase (gst). |
2019-07-29 |
2023-08-13 |
rat |
| Meng Zhang, Yuan Yuan, Qing Wang, Xiaobo Li, Jiuzhang Men, Mingxin Li. The Chinese medicine Chai Hu Li Zhong Tang protects against non-alcoholic fatty liver disease by activating AMPKα. Bioscience reports. vol 38. issue 6. 2019-07-22. PMID:30291215. |
rats in an animal model of nafld were treated with chlzt, and their serum levels of cholesterol (tc), triglycerides (tg), high density lipoprotein-cholesterol (hdl-c), low density lipoprotein-cholesterol (ldl-c), aspartate aminotransferase (ast), and alanine aminotransferase (alt) were detected with an automatic biochemical analyzer. |
2019-07-22 |
2023-08-13 |
rat |
| Yu Wu, Wen-Jing Tian, Shuo Gao, Zu-Jian Liao, Guang-Hui Wang, Jir-Mehng Lo, Pei-Hsin Lin, De-Quan Zeng, Da-Ren Qiu, Xiang-Zhong Liu, Mi Zhou, Ting Lin, Hai-Feng Che. Secondary metabolites of petri-dish cultured Antrodia camphorata and their hepatoprotective activities against alcohol-induced liver injury in mice. Chinese journal of natural medicines. vol 17. issue 1. 2019-07-19. PMID:30704622. |
in mice alcohol-induced liver injury model, triglyceride (tg), aspartate aminotransferase (ast), alanine aminotransferase (alt), and malondialdehyde (mda) had been reduced by the pdca powder as well as the main content antcin k, which indicated that the pdca could protect alcoholic liver injury in mice model and antcin k could be the effective component responsible for the hepatoprotective activities of pdca against alcoholic liver diseases. |
2019-07-19 |
2023-08-13 |
mouse |
| Dahu Li, Houjiu Wu, Huating Do. Weight loss effect of sweet orange essential oil microcapsules on obese SD rats induced by high-fat diet. Bioscience, biotechnology, and biochemistry. vol 83. issue 5. 2019-07-01. PMID:30741117. |
abbreviations: soeo: sweet orange essential oil; tc: total cholesterol; tg: triglyceride; ldl-c: low-density lipoprotein cholesterol; hdl-c: high-density lipoprotein cholesterol; pparα: peroxisome proliferators-activated receptor-α; pparγ: peroxisome proliferators-activated receptor-γ; ucp2: uncoupling protein 2; hsl: hormone sensitive lipase; cpt1: carnitine palmitoyltransferase i; acc: acetyl-coa carboxylase; npy: neuropeptide y; lep: leptin; ins: insulin; alt: alanine aminotransferase; ast: aspartate aminotransferase. |
2019-07-01 |
2023-08-13 |
rat |
| Yimin Yin, Huanhuan Liu, Zicong Zheng, Rongrong Lu, Zhuoqin Jian. Genistein can ameliorate hepatic inflammatory reaction in nonalcoholic steatohepatitis rats. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 111. 2019-06-21. PMID:30841442. |
with corresponding kits, several indicators were detected, namely, serum triglyceride (tg), total cholesterol (tc), high density lipoprotein cholesterol (hdl-c), low density lipoprotein cholesterol (ldl-c), liver tc and tg, and serum alanine aminotransferase (alt), aspartate aminotransferase (ast), blood glucose and serum endotoxin. |
2019-06-21 |
2023-08-13 |
rat |
| Xia Li, Quan Jin, Yu Zhang, Yan-Ling Wu, Cheng-Min Jin, Ben-Wen Cui, Ying Li, Ming-Ji Jin, Yue Shang, Min Jiang, Hong-Xu Yang, Mei Wu, Jian Liu, Li-Hua Lian, Ji-Xing Na. Inhibition of P2X7R-NLRP3 Inflammasome Activation by Pleurotus citrinopileatus: A Possible Protective Role in Alcoholic Hepatosteatosis. Journal of agricultural and food chemistry. vol 66. issue 50. 2019-06-17. PMID:30497264. |
in both models, p. citrinopileatus decreased serum alanine aminotransferase (alt), aspartate transaminase (ast), triglyceride (tg), and hepatic tg levels. |
2019-06-17 |
2023-08-13 |
mouse |
| Göknur Aktay, Şule Öner Gürsoy, Umut Uyumlu, Songül Ünüvar, Nevin İlha. Protective effect of atorvastatin on oxidative stress in streptozotocin-induced diabetic rats independently their lipid-lowering effects. Journal of biochemical and molecular toxicology. vol 33. issue 5. 2019-06-17. PMID:30657622. |
fasting blood glucose (fbg), triglyceride (tg), total cholesterol (tc), and high-density lipoprotein (hdl) levels, as well as alanine aminotransferase (alt) and aspartate aminotransferase (ast) enzyme activities, were measured 7 weeks after the administration of stz and atorvastatin. |
2019-06-17 |
2023-08-13 |
rat |
| Xin Liu, Kai Huang, Ziran Niu, Dan Mei, Bo Zhan. Protective effect of isochlorogenic acid B on liver fibrosis in non-alcoholic steatohepatitis of mice. Basic & clinical pharmacology & toxicology. vol 124. issue 2. 2019-05-29. PMID:30180301. |
the levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and hepatic hydroxyproline (hyp), cholesterol (cho) and triglyceride (tg) were also significantly decreased by icab. |
2019-05-29 |
2023-08-13 |
mouse |
| Weiyan Zhang, Yue Sun, Wei Liu, Jinling Dong, Jinglong Che. SIRT1 mediates the role of RNA-binding protein QKI 5 in the synthesis of triglycerides in non-alcoholic fatty liver disease mice via the PPARα/FoxO1 signaling pathway. International journal of molecular medicine. vol 43. issue 3. 2019-05-20. PMID:30664220. |
in addition, serum levels of total cholesterol, tg, alanine aminotransferase and aspartate aminotransferase were assessed using an automatic biochemistry analyzer. |
2019-05-20 |
2023-08-13 |
mouse |
| Min Xu, Xi-Ming Zheng, Fang Jiang, Wei-Qiang Qi. MicroRNA-190b regulates lipid metabolism and insulin sensitivity by targeting IGF-1 and ADAMTS9 in non-alcoholic fatty liver disease. Journal of cellular biochemistry. vol 119. issue 7. 2019-05-08. PMID:29575055. |
knockdown of mir-190b decreased aspartate transaminase (ast), alanine transaminase (alt), triglyceride (tg), and total cholesterol (tc). |
2019-05-08 |
2023-08-13 |
mouse |
| Ines Amara, Rim Timoumi, Emna Annabi, Fadwa Neffati, Mohamed Fadhel Najjar, Chayma Bouaziz, Salwa Abid-Essef. Di (2-ethylhexyl) phthalate induces cardiac disorders in BALB/c mice. Environmental science and pollution research international. vol 26. issue 8. 2019-05-03. PMID:30659488. |
we assessed the effect of dehp on cardiac injury using biochemical profile (such as aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), creatinine phosphokinase (cpk), total cholesterol (t-chol), triglyceride (tg), high-density lipoprotein cholesterol (hdl-c), and low-density lipoprotein cholesterol (ldl-c)), parameters related to myocardiac oxidative stress, such as malondialdehyde (mda) level, protein carbonyl (pc) concentration, and dna fragmentation. |
2019-05-03 |
2023-08-13 |
mouse |
| Xiaona Gao, Ping Liu, Cong Wu, Tiancheng Wang, Guohui Liu, Huabin Cao, Caiying Zhang, Guoliang Hu, Xiaoquan Gu. Effects of fatty liver hemorrhagic syndrome on the AMP-activated protein kinase signaling pathway in laying hens. Poultry science. vol 98. issue 5. 2019-04-19. PMID:30608557. |
liver tissues were also collected on the 100th day to determine the levels of total cholesterol, triglyceride (tg), high-density lipoprotein cholesterol (hdl-ch), low-density lipoprotein cholesterol (ldl-ch), aspartate aminotransferase, and alanine aminotransferase in plasma. |
2019-04-19 |
2023-08-13 |
Not clear |
| Jiangning Yin, Hanqing Wang, Guoyuan L. Umbelliferone alleviates hepatic injury in diabetic db/db mice via inhibiting inflammatory response and activating Nrf2-mediated antioxidant. Bioscience reports. vol 38. issue 4. 2019-04-05. PMID:29967293. |
at 28 days after drug administration, blood samples were obtained for the analysis of lipids and enzymes related to hepatic function, including alanine aminotransferase (alt), aspartate aminotransaminase (ast) and total cholesterol (tc) and triglyceride (tg). |
2019-04-05 |
2023-08-13 |
mouse |
| Joo Wan Kim, You-Suk Lee, Du Jin Seol, Il Je Cho, Sae Kwang Ku, Jae-Suk Choi, Hae-Jeung Le. Anti-obesity and fatty liver-preventing activities of Lonicera caerulea in high-fat diet-fed mice. International journal of molecular medicine. vol 42. issue 6. 2019-03-06. PMID:30221679. |
significant increases in fat pad weight, body weight, fat accumulation (body and abdominal fat density, and thickness of the periovarian and abdominal wall) and serum biochemical levels (aspartate transaminase, alanine aminotransferase, alkaline phosphatase, lactate dehydrogenase, γ‑glutamyltransferase, total cholesterol, low‑density lipoprotein and tg, with the exception of high‑density lipoprotein) were observed in hfd‑fed mice. |
2019-03-06 |
2023-08-13 |
mouse |
| Murat Giriş, Semra Doğru-Abbasoğlu, Merva Soluk-Tekkeşin, Vakur Olgaç, Müjdat Uysa. Effect of betaine treatment on the regression of existing hepatic triglyceride accumulation and oxidative stress in rats fed on high fructose diet. General physiology and biophysics. vol 37. issue 5. 2019-02-15. PMID:30047921. |
hfrd feeding caused insulin resistance, elevated triglyceride (tg) and tumor necrosis factor-alfa (tnf-α) levels, alanine aminotransferase (alt) and aspartate transaminase (ast) activities in serum. |
2019-02-15 |
2023-08-13 |
rat |
| Yashu Xu, Cheng Yang, Shujun Zhang, Jiajun Li, Qing Xiao, Wenxiang Huan. Ginsenoside Rg1 Protects against Non-alcoholic Fatty Liver Disease by Ameliorating Lipid Peroxidation, Endoplasmic Reticulum Stress, and Inflammasome Activation. Biological & pharmaceutical bulletin. vol 41. issue 11. 2019-02-11. PMID:30135326. |
rg1 significantly reduced liver weight, serum alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), liver free fatty acids (ffas) and malondialdehyde (mda) levels, and increased superoxide dismutase (sod) activity. |
2019-02-11 |
2023-08-13 |
mouse |