| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Xiaolei Hu, Dongsheng Yu, Langen Zhuang, Mengyun Zhou, Zhaoming Shi, Guoxi Jin, Xiaomei Zhan. Geniposide improves hepatic inflammation in diabetic db/db mice. International immunopharmacology. vol 59. 2018-10-03. PMID:29655055. |
the oral glucose tolerance test was performed, and the levels of insulin, alanine aminotransferase (alt), aspartate aminotransaminase (ast), total cholesterol (tc) and triglyceride (tg) were determined. |
2018-10-03 |
2023-08-13 |
mouse |
| Young Mi Cho, Jeong Eun Kwon, Minkyung Lee, Youngsung Lea, Do-Yong Jeon, Hyeong Jun Kim, Se Chan Kan. Agrimonia eupatoria L. (Agrimony) Extract Alters Liver Health in Subjects with Elevated Alanine Transaminase Levels: A Controlled, Randomized, and Double-Blind Trial. Journal of medicinal food. vol 21. issue 3. 2018-09-25. PMID:29486131. |
significant group and time interactions were found in alt (p = .038), aspartate aminotransferase (p = .040), and tg (p = .010). |
2018-09-25 |
2023-08-13 |
human |
| Qianping Zhang, Opeyemi J Olatunji, Hongxia Chen, Adesola J Tola, Omolara O Oluwaniy. Evaluation of the Anti-Diabetic Activity of Polysaccharide from Cordyceps cicadae in Experimental Diabetic Rats. Chemistry & biodiversity. vol 15. issue 8. 2018-09-12. PMID:29874416. |
blood glucose level, total cholesterol (tc), triglyceride (tg), low density lipoprotein (ldl), high density lipoprotein (hdl), alanine transaminase (alt), aspartate aminotransferase (ast), alkaline phosphate (alp), creatinine (crea), urea, malondialdehyde (mda), superoxide dismutase (sod), glutathione peroxidase (gsh) were determined. |
2018-09-12 |
2023-08-13 |
rat |
| Yinglan Peng, Ke H. Effect of garlic on rats with chronic intermittent hypoxia combined with diabetes mellitus. Molecular medicine reports. vol 17. issue 4. 2018-08-30. PMID:29436658. |
serum thiobarbituric acid reactive substances (tbars), glutathione s‑transferase (gst), uric acid (ua), urine protein (up), total cholesterol (tc), triglycerides (tg), total lipids (tl), aspartate aminotransferase (ast), alanine aminotransferase (alt), lactate dehydrogenase (ldh), alkaline phosphatase (alp) and acid phosphatase (acp) increased in the cih, dm and cih‑dm groups, while albumin and superoxide dismutase (sod) decreased in all model groups compared with healthy controls. |
2018-08-30 |
2023-08-13 |
rat |
| Junqing Huang, Xiaoqi Wang, Guanyu Tao, Yuan Song, Chitang Ho, Jie Zheng, Shiyi O. Feruloylated oligosaccharides from maize bran alleviate the symptoms of diabetes in streptozotocin-induced type 2 diabetic rats. Food & function. vol 9. issue 3. 2018-08-24. PMID:29508881. |
among all the treatments, the oral administration of 600 mg per kg bw per d fos showed the best therapeutic effects on the diabetic rats by significantly lowering the levels of fasting plasma glucose (fpg), fasting insulin, tg, ldl-c, aspartate transaminase, creatine kinase and lactate dehydrogenase in plasma, while increasing the level of plasma hdl-c. |
2018-08-24 |
2023-08-13 |
rat |
| K Mladenovska, A Daka Grapci, M Vavlukis, A Kapedanovska, A Eftimov, N Matevska Geshkovska, D Nebija, A J Dimovsk. Influence of Die Pharmazie. vol 72. issue 5. 2018-08-22. PMID:29441875. |
as parameters of atorvastatin response, total cholesterol (tc), low-density lipoprotein cholesterol (ldl-c), high-density lipoprotein cholesterol (hdl-c), triglycerides (tg), apolipoprotein a (apoai), apolipoprotein b (apob), lipoprotein(a) (lp(a)), creatine phosphokinase (cpk), alanine aminotransferase (alt) and aspartate aminotransferase (ast) were measured, using standard laboratory methods, at baseline and after 3 months of treatment. |
2018-08-22 |
2023-08-13 |
Not clear |
| Huafeng Yin, Lihao Huang, Ting Ouyang, Lvyi Che. Baicalein improves liver inflammation in diabetic db/db mice by regulating HMGB1/TLR4/NF-κB signaling pathway. International immunopharmacology. vol 55. 2018-08-20. PMID:29223854. |
the results exhibited that ba significantly restored the blood glucose in oral glucose tolerance test (ogtt) and inhibited the levels of insulin, alanine aminotransferase (alt), aspartate aminotransaminase (ast), total cholesterol (tc) and triglyceride (tg) in c57bl/ksj-db/db mice. |
2018-08-20 |
2023-08-13 |
mouse |
| Mohd Salim Reshi, Chhavi Uthra, Deepa Yadav, Samta Sharma, Asha Singh, Anjali Sharma, Amita Jaswal, Neelu Sinha, Sadhana Shrivastava, Sangeeta Shukl. Silver nanoparticles protect acetaminophen induced acute hepatotoxicity: A biochemical and histopathological approach. Regulatory toxicology and pharmacology : RTP. vol 90. 2018-07-23. PMID:28827191. |
treatment with agnps recouped the levels of serum aspartate amino transaminase (ast), alanine amino transaminase (alt), lactate dehydrogenase (ldh), alkaline phosphatase (alp), bilirubin, triglyceride (tg) and cholesterol in dose dependent manner. |
2018-07-23 |
2023-08-13 |
rat |
| Jingxian Luo, Jiao Song, Longzhou Liu, Bo Xue, Guangming Tian, Ye Yan. Effect of epigallocatechin gallate on growth performance and serum biochemical metabolites in heat-stressed broilers. Poultry science. vol 97. issue 2. 2018-07-17. PMID:29253233. |
at d 35 of age, heat stress reduced (p < 0.05) the body weight (bw), feed intake (fi) and the contents of serum total protein (tp) and glucose (glu); inhibited (p < 0.05) alkaline phosphatase (alp) activity; but increased (p < 0.05) the contents of uric acid (ua), cholesterol (chol), triglyceride (tg), and the activities of creatine kinase (ck), lactate dehydrogenase (ldh), aspartate aminotransferase (ast). |
2018-07-17 |
2023-08-13 |
cat |
| Ling Li, Yifei Wu, Fangyuan Yin, Qin Feng, Xiaoliang Dong, Ruhui Zhang, Zhimin Yin, Lan Lu. Fructose 1, 6-diphosphate prevents alcohol-induced liver injury through inhibiting oxidative stress and promoting alcohol metabolism in mice. European journal of pharmacology. vol 815. 2018-07-05. PMID:28943104. |
the in vivo experiments demonstrated that fdp, orally administered to mice, dose-dependently suppressed alcohol (50%, v/v, 12ml/kg)-induced increase of serum activities of alanine aminotransferase (alt) and aspartate aminotransferase (ast), serum triglyceride (tg) level and hepatic malondialdehyde (mda) level. |
2018-07-05 |
2023-08-13 |
mouse |
| Zhen Yang, Hongmei Zhang, Yixin Niu, Weiwei Zhang, Lingfei Zhu, Xiaoyong Li, Shuai Lu, Jiangao Fan, Xiaoying Li, Guang Ning, Li Qin, Qing S. Circulating periostin in relation to insulin resistance and nonalcoholic fatty liver disease among overweight and obese subjects. Scientific reports. vol 6. 2018-06-01. PMID:27885258. |
furthermore, periostin levels among overweight and obese subjects were correlated with aspartate aminotransferase (r = 0.102, p = 0.004), alanine aminotransferase (r = 0.108, p = 0.003), waist circumference (r = 0.111, p = 0.002), homeostasis model assessment index-insulin resistance (r = 0.154, p < 0.001) and fasting plasma insulin (r = 0.098, p = 0.006), tg (r = 0.117, p = 0.001). |
2018-06-01 |
2023-08-13 |
human |
| Rubén Díaz-Rúa, Jaap Keijer, Andreu Palou, Evert M van Schothorst, Paula Olive. Long-term intake of a high-protein diet increases liver triacylglycerol deposition pathways and hepatic signs of injury in rats. The Journal of nutritional biochemistry. vol 46. 2018-04-26. PMID:28454041. |
in concordance with changes at gene expression level, we observed increased liver tg content and increased serum markers of hepatic injury/inflammation (aspartate transaminase, c-reactive protein and tnf-alpha). |
2018-04-26 |
2023-08-13 |
rat |
| Mi-Ryung Kim, Joo-Wan Kim, Jeong Been Park, Yong-Ki Hong, Sae Kwang Ku, Jae-Suk Cho. Anti-obesity effects of yellow catfish protein hydrolysate on mice fed a 45% kcal high-fat diet. International journal of molecular medicine. vol 40. issue 3. 2018-04-17. PMID:28713910. |
the hfd-fed control mice exhibited noticeable increase in body weight, and whole-body and abdominal fat densities, periovarian and abdominal wall-deposited fat pad weight, as well as in the levels of triglycerides (tg), blood total cholesterol (tc), low-density lipoprotein, alanine aminotransferase, aspartate aminotransferase, creatinine, blood urea nitrogen, and in the fecal tg and tc contents. |
2018-04-17 |
2023-08-13 |
mouse |
| Jean-Jacques Yao Adjoumani, Kaizhou Wang, Man Zhou, Wenbin Liu, Dingdong Zhan. Effect of dietary betaine on growth performance, antioxidant capacity and lipid metabolism in blunt snout bream fed a high-fat diet. Fish physiology and biochemistry. vol 43. issue 6. 2018-04-10. PMID:28963592. |
significantly higher (p < 0.05), plasma total cholesterol (tc), triglycerides (tg), low-density lipoprotein (ldl), aspartate transaminase (ast), alanine transaminase (alt), cortisol, and lower high-density lipoprotein (hdl) content were observed in hfd but were improved when supplemented with 1.2% betaine. |
2018-04-10 |
2023-08-13 |
cat |
| Zuiming Jiang, Min Gu, Jiaqiang Liu, Huiyuan Li, Jun Peng, Yuejun Zhan. Anticancer activity of crocin against cervical carcinoma (HeLa cells): Bioassessment and toxicity evaluation of crocin in male albino rats. Journal of photochemistry and photobiology. B, Biology. vol 180. 2018-04-06. PMID:29413694. |
alanine transaminase (alt), aspartate transaminase (ast), lactate dehydrogenase (ldh), alkaline phosphatase (alp), blood urea nitrogen (bun), creatinine, bilirubin, albumin and total protein were decreased, while glucose, cholesterol, tg, and gsh were increased. |
2018-04-06 |
2023-08-13 |
rat |
| Xiao-Xia Wang, Ting Ye, Mao Li, Xian Li, Ou Qiang, Cheng-Wei Tang, Rui Li. Effects of octreotide on hepatic glycogenesis in rats with high fat diet‑induced obesity. Molecular medicine reports. vol 16. issue 1. 2018-03-26. PMID:28534956. |
following sacrifice, their body weights and lengths, fasting plasma glucose (fpg), fasting insulin (fins), serum triglyceride (tg), total cholesterol (tc), free fatty acid (ffa), alanine aminotransferase (alt) and aspartate aminotransferase (ast) levels were measured. |
2018-03-26 |
2023-08-13 |
mouse |
| Tong Zhou, Yu-Jie Zhang, Dong-Ping Xu, Fang Wang, Yue Zhou, Jie Zheng, Ya Li, Jiao-Jiao Zhang, Hua-Bin L. Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice. BioMed research international. vol 2017. 2018-03-07. PMID:28567423. |
the results showed that lemon juice significantly inhibited alcohol-induced increase of alanine transaminase (alt), aspartate transaminase (ast), hepatic tg, and lipid peroxidation levels in a dose-dependent manner. |
2018-03-07 |
2023-08-13 |
mouse |
| Wen-Ping Jiang, Shyh-Shyun Huang, Yoshikazu Matsuda, Hiroshi Saito, Naoto Uramaru, Hui-Ya Ho, Jin-Bin Wu, Guan-Jhong Huan. Protective Effects of Tormentic Acid, a Major Component of Suspension Cultures of Eriobotrya japonica Cells, on Acetaminophen-Induced Hepatotoxicity in Mice. Molecules (Basel, Switzerland). vol 22. issue 5. 2018-03-02. PMID:28524081. |
pretreatment with ta prevented the elevation of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (t-bil), total cholesterol (tc), triacylglycerol (tg), and liver lipid peroxide levels in apap-treated mice and markedly reduced apap-induced histological alterations in liver tissues. |
2018-03-02 |
2023-08-13 |
mouse |
| Hongshan Li, Hao Ying, Airong Hu, Yaoren Hu, Dezhou L. Therapeutic Effect of Gypenosides on Nonalcoholic Steatohepatitis via Regulating Hepatic Lipogenesis and Fatty Acid Oxidation. Biological & pharmaceutical bulletin. vol 40. issue 5. 2018-02-12. PMID:28458350. |
we found that liver tissues showed significant hepatic steatosis and vacuolar degeneration with significantly higher triglyceride (tg), free fatty acid (ffa) and malonyl coa, serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyl transferase (ggt) activities in model group versus normal control group (p<0.01). |
2018-02-12 |
2023-08-13 |
rat |
| Hady Razak Hady, Magdalena Olszewska, Mikolaj Czerniawski, Dawid Groth, Inna Diemieszczyk, Patrycja Pawluszewicz, Adam Kretowski, Jerzy Robert Ladny, Jacek Dada. Different surgical approaches in laparoscopic sleeve gastrectomy and their influence on metabolic syndrome: A retrospective study. Medicine. vol 97. issue 4. 2018-02-02. PMID:29369197. |
statistical analysis of: body mass index (bmi), the percentage of excess weight loss (%ewl), the percentage of excess bmi loss (%ebmil), levels of glucose and insulin on an empty stomach, glycated hemoglobin (hba1c), insulin resistance (homeostatic model assessment of insulin resistance index-homa-ir), aspartate transaminase (ast), alanine transaminase (alt), total cholesterol, high-density lipoprotein (hdl), low-density lipoprotein (ldl), triglycerides (tg), and c-reactive protein (crp) were under investigation.statistically significant decrease in body mass, bmi, %ewl, %ebl, glucose, and insulin concentrations has been observed in all studied groups. |
2018-02-02 |
2023-08-13 |
Not clear |