| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Tong Zhou, Yu-Jie Zhang, Dong-Ping Xu, Fang Wang, Yue Zhou, Jie Zheng, Ya Li, Jiao-Jiao Zhang, Hua-Bin L. Protective Effects of Lemon Juice on Alcohol-Induced Liver Injury in Mice. BioMed research international. vol 2017. 2018-03-07. PMID:28567423. |
the results showed that lemon juice significantly inhibited alcohol-induced increase of alanine transaminase (alt), aspartate transaminase (ast), hepatic tg, and lipid peroxidation levels in a dose-dependent manner. |
2018-03-07 |
2023-08-13 |
mouse |
| Wen-Ping Jiang, Shyh-Shyun Huang, Yoshikazu Matsuda, Hiroshi Saito, Naoto Uramaru, Hui-Ya Ho, Jin-Bin Wu, Guan-Jhong Huan. Protective Effects of Tormentic Acid, a Major Component of Suspension Cultures of Eriobotrya japonica Cells, on Acetaminophen-Induced Hepatotoxicity in Mice. Molecules (Basel, Switzerland). vol 22. issue 5. 2018-03-02. PMID:28524081. |
pretreatment with ta prevented the elevation of serum aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (t-bil), total cholesterol (tc), triacylglycerol (tg), and liver lipid peroxide levels in apap-treated mice and markedly reduced apap-induced histological alterations in liver tissues. |
2018-03-02 |
2023-08-13 |
mouse |
| Hongshan Li, Hao Ying, Airong Hu, Yaoren Hu, Dezhou L. Therapeutic Effect of Gypenosides on Nonalcoholic Steatohepatitis via Regulating Hepatic Lipogenesis and Fatty Acid Oxidation. Biological & pharmaceutical bulletin. vol 40. issue 5. 2018-02-12. PMID:28458350. |
we found that liver tissues showed significant hepatic steatosis and vacuolar degeneration with significantly higher triglyceride (tg), free fatty acid (ffa) and malonyl coa, serum alanine aminotransferase (alt), aspartate aminotransferase (ast) and gamma-glutamyl transferase (ggt) activities in model group versus normal control group (p<0.01). |
2018-02-12 |
2023-08-13 |
rat |
| Hady Razak Hady, Magdalena Olszewska, Mikolaj Czerniawski, Dawid Groth, Inna Diemieszczyk, Patrycja Pawluszewicz, Adam Kretowski, Jerzy Robert Ladny, Jacek Dada. Different surgical approaches in laparoscopic sleeve gastrectomy and their influence on metabolic syndrome: A retrospective study. Medicine. vol 97. issue 4. 2018-02-02. PMID:29369197. |
statistical analysis of: body mass index (bmi), the percentage of excess weight loss (%ewl), the percentage of excess bmi loss (%ebmil), levels of glucose and insulin on an empty stomach, glycated hemoglobin (hba1c), insulin resistance (homeostatic model assessment of insulin resistance index-homa-ir), aspartate transaminase (ast), alanine transaminase (alt), total cholesterol, high-density lipoprotein (hdl), low-density lipoprotein (ldl), triglycerides (tg), and c-reactive protein (crp) were under investigation.statistically significant decrease in body mass, bmi, %ewl, %ebl, glucose, and insulin concentrations has been observed in all studied groups. |
2018-02-02 |
2023-08-13 |
Not clear |
| Xudong Liu, Zhen Shen, Hongxing Zhang, Jian Liang, Hai Li. Interleukin-21 Is Associated with Early Antiviral Response in Patients with Hepatitis B e Antigen-Positive Chronic Hepatitis B and Nonalcoholic Fatty Liver Disease. Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research. vol 36. issue 6. 2018-01-12. PMID:26840345. |
baseline il-21 was associated with bmi, ct ratio of liver/spleen, tg, chol, and hbeag level in chb + nafld patients, whose il-21, alanine aminotransferase, aspartate aminotransferase, chol, bmi, and ct ratio of liver/spleen at baseline was associated with evr. |
2018-01-12 |
2023-08-13 |
Not clear |
| Ting Xu, Junjun Zhou, Jie Zhu, Shuai Zhang, Ning Zhang, Yan Zhao, Chunchun Ding, Xue Shi, Jihong Ya. Carnosic acid protects non-alcoholic fatty liver-induced dopaminergic neuron injury in rats. Metabolic brain disease. vol 32. issue 2. 2018-01-12. PMID:27957651. |
we found that continued ca administration reduced lipid accumulation marked by decreases in alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), total cholesterol (tc) and low-density lipoprotein cholesterol (ldl-c) levels, and an increase in high-density lipoprotein cholesterol (hdl-c) level in the serum. |
2018-01-12 |
2023-08-13 |
rat |
| Long Wang, Jinghui Guo, Jianping L. Risk factor compositions of nonalcoholic fatty liver disease change with body mass index in males and females. Oncotarget. vol 7. issue 24. 2018-01-05. PMID:27248665. |
triglycerides (tg), alanine transaminase (alt), aspartate transaminase (ast), and uric acid were steady risk factors for nafld in males. |
2018-01-05 |
2023-08-13 |
human |
| Lorena Bavia, Íris Arantes de Castro, Bruno Cogliati, Juliano Bertollo Dettoni, Venancio Avancini Ferreira Alves, Lourdes Isaa. Complement C5 controls liver lipid profile, promotes liver homeostasis and inflammation in C57BL/6 genetic background. Immunobiology. vol 221. issue 7. 2017-12-04. PMID:26896155. |
serum parameters of liver function as alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (ap), albumin, glucose, triglycerides (tg) and cholesterol were evaluated. |
2017-12-04 |
2023-08-13 |
mouse |
| Jie Yu, Xuesong Yang, Ya Luo, Xuefeng Yang, Mengxue Yang, Jin Yang, Jie Zhou, Feng Gao, Liting He, Jie X. Adverse effects of chronic exposure to nonylphenol on non-alcoholic fatty liver disease in male rats. PloS one. vol 12. issue 7. 2017-10-04. PMID:28686624. |
exposure to np-hshfd induced the increases in plasma alanine aminotransferase (alt), aspartate aminotransferase (ast), cholesterol (tc), triglyceride (tg) and low density lipoprotein (ldl) as compared to the c-nd group. |
2017-10-04 |
2023-08-13 |
rat |
| Yuno Song, Hong-Duck Kim, Min-Kwon Lee, Il-Hwa Hong, Chung-Kil Won, Hyoung-Woo Bai, Seung Sik Lee, SungBeom Lee, Byung Yeoup Chung, Jae-Hyeon Ch. Maysin and Its Flavonoid Derivative from Centipedegrass Attenuates Amyloid Plaques by Inducting Humoral Immune Response with Th2 Skewed Cytokine Response in the Tg (APPswe, PS1dE9) Alzheimer's Mouse Model. PloS one. vol 12. issue 1. 2017-08-08. PMID:28072821. |
to minimize the toxicity of the extracted cg, we addressed the liver toxicity in response to the cg extract treatment in tg mice using relevant markers, such as aspartate aminotransferase (ast)/ alanine aminotransferase (alt) measurements in serum. |
2017-08-08 |
2023-08-13 |
mouse |
| Y Li, H Y Ding, X C Wang, S B Feng, X B Li, Z Wang, G W Liu, X W L. An association between the level of oxidative stress and the concentrations of NEFA and BHBA in the plasma of ketotic dairy cows. Journal of animal physiology and animal nutrition. vol 100. issue 5. 2017-08-07. PMID:27079290. |
plasma samples were analysed by standard biochemical techniques and elisa to determine traditional metabolic parameters: triglyceride (tg), phosphonium (p), calcium (ca), aspartate aminotransferase (ast), alanine aminotransferase (alt), alkaline phosphatase (alp), total protein (tp), albumin (alb), immune globulin (ig), total cholesterol (tc), high-density lipoprotein (hdl), very low-density lipoprotein (vldl) and lactate dehydrogenase (ldh); energy metabolism indices: glucose, β-hydroxybutyrate (bhba) and non-esterified fatty acids (nefa); and indices of oxidative status: malondialdehyde (mda), hydrogen peroxide (h2 o2 ), vitamin c, vitamin e, superoxide dismutase (sod), glutathione peroxidase (gsh-px), catalase (cat), xanthine oxidase (xod) and total antioxidant capacity (taoc). |
2017-08-07 |
2023-08-13 |
cat |
| Lu Yao, Weina Chen, Chang Han, Tong W. Microsomal prostaglandin E synthase-1 protects against Fas-induced liver injury. American journal of physiology. Gastrointestinal and liver physiology. vol 310. issue 11. 2017-06-08. PMID:27102561. |
compared with wild-type (wt) mice, the mpges-1 tg mice showed less liver hemorrhage, lower serum alanine transaminase (alt) and aspartate transaminase (ast) levels, less hepatic necrosis/apoptosis, and lower level of caspase cascade activation after intraperitoneal injection of the anti-fas antibody jo2. |
2017-06-08 |
2023-08-13 |
mouse |
| Soo-Im Choi, In-Hee Cho, Se Hee Han, Yoon-Jung Jeon, Jong-Gil Choi, Jin-Sun Kim, Je-Hyuk Le. Antiobesity Effects of Salvia plebeia R. Br. Extract in High-Fat Diet-Induced Obese Mice. Journal of medicinal food. vol 19. issue 11. 2017-05-26. PMID:27705068. |
in addition, obesity resulting from feeding hfd to the mice was confirmed by the increase of glucose level, aspartate transaminase, alanine transaminase, triglyceride (tg), high-density lipoprotein cholesterol, very low-density lipoprotein-c, leptin, and adiponectin in blood. |
2017-05-26 |
2023-08-13 |
mouse |
| Jialin Gao, Yao Zhang, Cui Yu, Fengbiao Tan, Lizhuo Wan. Spontaneous nonalcoholic fatty liver disease and ER stress in Sidt2 deficiency mice. Biochemical and biophysical research communications. vol 476. issue 4. 2017-05-23. PMID:27233614. |
gradual increases in serum triglyceride (tg) and free fatty acid, as well as elevated aspartate transaminase and alanine transaminase levels were observed in sidt2(-/-) mice fed a normal diet from the age of 3 months, suggesting the presence of lipid metabolism disorders and impaired liver function in these mice. |
2017-05-23 |
2023-08-13 |
mouse |
| Lu Yao, Weina Chen, Kyoungsub Song, Chang Han, Chandrashekhar R Gandhi, Kyu Lim, Tong W. 15-hydroxyprostaglandin dehydrogenase (15-PGDH) prevents lipopolysaccharide (LPS)-induced acute liver injury. PloS one. vol 12. issue 4. 2017-04-25. PMID:28423012. |
compared to the wild type mice, the 15-pgdh tg mice showed lower levels of alanine aminotransferase (alt) and aspartate aminotransferase (ast), less liver tissue damage, less hepatic apoptosis/necrosis, less macrophage activation, and lower inflammatory cytokine production. |
2017-04-25 |
2023-08-13 |
mouse |
| Liya Liu, Jinyan Zhao, Ying Li, Yun Wan, Jiumao Lin, Aling Shen, Wei Xu, Huang Li, Yuchen Zhang, Jianfeng Xu, Jun Peng, Zhenfeng Hon. Artemisia capillaris formula inhibits hepatic steatosis via an miR‑122‑induced decrease in fatty acid synthase expression in vivo and in vitro. Molecular medicine reports. vol 13. issue 6. 2017-03-20. PMID:27081834. |
serum alanine transaminase (alt), aspartate aminotransferase (ast), triglycerides (tg), total cholesterol (tc), high‑density lipoprotein cholesterol (hdl‑c), low‑density lipoprotein cholesterol (ldl‑c), and steatotic hepg2 human liver carcinoma cell tc and tg levels were measured. |
2017-03-20 |
2023-08-13 |
human |
| Sonia Agostinho Nido, Shituleni Andreas Shituleni, Berhe Mekonnen Mengistu, Yunhuan Liu, Alam Zeb Khan, Fang Gan, Shahnawaz Kumbhar, Kehe Huan. Effects of Selenium-Enriched Probiotics on Lipid Metabolism, Antioxidative Status, Histopathological Lesions, and Related Gene Expression in Mice Fed a High-Fat Diet. Biological trace element research. vol 171. issue 2. 2017-02-07. PMID:26546553. |
p, ss, or sp supplementation also significantly reversed the changes of alanine aminotransferase (ast), aspartate aminotransferase (alt), total cholesterol (tc), triglyceride (tg), low-density lipoprotein (ldl), total protein (tp), high-density lipoprotein (hdl), glutathione peroxidase (gsh-px), superoxide dismutase (sod), catalasa (cat), and malondialdehyde (mda) levels induced by hfd. |
2017-02-07 |
2023-08-13 |
mouse |
| Jiali Zhu, Keke Xu, Xuemei Zhang, Jiahong Cao, Zhanrong Jia, Ruocong Yang, Chaoying Ma, Chang Chen, Tiane Zhang, Zhiyong Ya. Studies on the regulation of lipid metabolism and its mechanism of the iridoids rich fraction in Valeriana jatamansi Jones. Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie. vol 84. 2017-02-01. PMID:27832992. |
body weight, liver index, total cholesterol (tc), triglyceride (tg), low-density lipoprotein cholesterol (ldl-c), and high-density lipoprotein cholesterol (hdl-c) in both serum and liver, as well as total bile acid (tba), aspartate aminotransferase (ast), and alanine aminotransferase (alt) in serum were measured. |
2017-02-01 |
2023-08-13 |
rat |
| Na-Hyun Kim, Jeong-Doo Heo, Tae Bum Kim, Jung-Rae Rho, Min Hye Yang, Eun Ju Jeon. Protective Effects of Ethyl Acetate Soluble Fraction of Limonium tetragonum on Diethylnitrosamine-Induced Liver Fibrosis in Rats. Biological & pharmaceutical bulletin. vol 39. issue 6. 2017-01-31. PMID:27251505. |
induced significant reductions in serum alanine transaminase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), gamma glutamyl transferase (ggt), and triglycerides (tg) in den-injected rats. |
2017-01-31 |
2023-08-13 |
mouse |
| J F Huang, T Zhan, X L Yu, Q A He, W J Huang, L Z Lin, Y T Du, Y T Pa. Therapeutic effect of Pleurotus eryngii cellulose on experimental fatty liver in rats. Genetics and molecular research : GMR. vol 15. issue 1. 2017-01-19. PMID:26985922. |
measured levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), total cholesterol (tc), and total triglyceride (tg); the activity of malondialdehyde (mda), superoxide dismutase (sod), hepatic lipase (hl), and lipoprotein lipase; and liver histopathological changes. |
2017-01-19 |
2023-08-13 |
rat |