| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Wei Li, Xin-Nan Qu, Ye Han, Si-Wen Zheng, Jia Wang, Ying-Ping Wan. Ameliorative effects of 5-hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on alcoholic liver oxidative injury in mice. International journal of molecular sciences. vol 16. issue 2. 2015-09-25. PMID:25622257. |
our results showed that the activities of alt (alanine aminotransferase), ast (aspartate transaminase), tc (total cholesterol), tg (triglyceride), l-dlc (low density lipoprotein) in serum and the levels of mda (malondialdehyde) in liver tissue, decreased significantly (p < 0.05) in the 5-hmf-treated group compared with the alcohol group. |
2015-09-25 |
2023-08-13 |
mouse |
| Ye Han, Qi Xu, Jiang-ning Hu, Xin-yue Han, Wei Li, Li-chun Zha. Maltol, a food flavoring agent, attenuates acute alcohol-induced oxidative damage in mice. Nutrients. vol 7. issue 1. 2015-09-24. PMID:25608939. |
for hepatoprotective activity in vivo, pretreatment with maltol (12.5, 25 and 50 mg/kg; 15 days) drastically prevented the elevated activities of aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp) and triglyceride (tg) in serum and the levels of malondialdehyde (mda), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β) in liver tissue (p < 0.05). |
2015-09-24 |
2023-08-13 |
mouse |
| Maria Bogdan, Isabela Silosi, Petra Surlin, Andrei Adrian Tica, Oana Sorina Tica, Tudor-Adrian Balseanu, Anne-Marie Rauten, Adrian Came. Salivary and serum biomarkers for the study of side effects of aripiprazole coprescribed with mirtazapine in rats. International journal of clinical and experimental medicine. vol 8. issue 5. 2015-07-29. PMID:26221370. |
also, serum levels for total cholesterol (tc), low and high-density lipoprotein (ldl, hdl), triglycerides (tg), aspartate aminotransferase (asat) and alanine amino transferase (alat) were assessed. |
2015-07-29 |
2023-08-13 |
rat |
| Adejuwon Adewale Adeneye, Olufunsho Awodele, Sheriff Aboyade Aiyeola, Adokiye Senibo Beneb. Modulatory potentials of the aqueous stem bark extract of Mangifera indica on carbon tetrachloride-induced hepatotoxicity in rats. Journal of traditional and complementary medicine. vol 5. issue 2. 2015-07-07. PMID:26151020. |
the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), total protein (tp), albumin (alb), triglyceride (tg), total cholesterol (tc), high density lipoprotein cholesterol (hdl-c), low density lipoprotein cholesterol (ldl-c), total bilirubin (tb), conjugated bilirubin (cb) and fasting blood glucose (fbg) levels were estimated. |
2015-07-07 |
2023-08-13 |
rat |
| Zafar Iqbal, Zia ur Rahman, Faqir Muhammad, Masood Akhtar, Mian Muhammad Awais, Tanweer Khaliq, Amar Nasir, Muhammad Nadeem, Kinza Khan, Hafiz Muhammad Arshad, Muhammad Abdul Basi. Effect of oxytocin on serum biochemistry, liver enzymes, and metabolic hormones in lactating Nili Ravi buffaloes. Tropical animal health and production. vol 47. issue 1. 2015-06-30. PMID:25281211. |
serum biochemical profile including glucose, total cholesterol (tchol), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), triglycerides (tg), total proteins (tp), c-reactive protein (crp), liver enzymes aspartate transaminase (ast), alanine transaminase (alt), and metabolic hormones triiodothyronine (t₃) and thyroxine (t₄) were studied. |
2015-06-30 |
2023-08-13 |
Not clear |
| Md Mahbubur Rahman, Sei-Jin Lee, A-Reum Mun, Gareeballah Osman Adam, Ra-Mi Park, Gi-Beum Kim, Hyung-Sub Kang, Jin-Shang Kim, Shang-Jin Kim, Sung-Zoo Ki. Relationships between blood Mg2+ and energy metabolites/enzymes after acute exhaustive swimming exercise in rats. Biological trace element research. vol 161. issue 1. 2015-06-22. PMID:25035192. |
after aese, blood mg(2+), tmg, k(+), partial pressure of carbon dioxide, lactate, total protein (t-pro), high-density lipoprotein (hdl), creatinine (cre), blood urea nitrogen (bun), uric acid (ua), alanine aminotransferase (alt), aspartate aminotransferase (ast), alanine phosphatase (alp), lactate dehydrogenase (ldh), and creatinine kinase (ck) were significantly increased, whereas ph, partial pressure of oxygen, oxygen saturation, the mg(2+)/tmg and ca(2+)/mg(2+) ratios, hco3 (-), glucose, triglyceride (tg), and low-density lipoprotein (ldl) were significantly decreased. |
2015-06-22 |
2023-08-13 |
rat |
| Zhiguo Wang, Bo Su, Sumei Fan, Haixia Fei, Wei Zha. Protective effect of oligomeric proanthocyanidins against alcohol-induced liver steatosis and injury in mice. Biochemical and biophysical research communications. vol 458. issue 4. 2015-05-26. PMID:25680468. |
the results showed that opc significantly improved alcohol-induced dyslipidemia and alleviated liver steatosis by reducing levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total triglyceride (tg), total cholesterol (tc), low-density cholesterol (ldl-c) and liver malondialdehyde (mda), and increasing levels of serum high-density lipoprotein (hdl-c), liver superoxide dismutase (sod). |
2015-05-26 |
2023-08-13 |
mouse |
| Yonghui Yin, Fanghua Qi, Zhenhua Song, Bo Zhang, Jialin Ten. Ferulic acid combined with astragaloside IV protects against vascular endothelial dysfunction in diabetic rats. Bioscience trends. vol 8. issue 4. 2015-05-19. PMID:25224628. |
blood samples were collected to measure levels of hemoglobin a1c (hbalc), triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), low density lipoproteins (ox-ldl), alanine aminotransferase (alt), aspartate aminotransferase (ast) and creatinine (cr), nitric oxide (no) and endothelial nitric oxide synthase (enos), and abdominal aorta tissue samples were collected for observing histological morphology changes of endothelium and detecting gene and protein expression of nuclear factor-κb (nf-κb) p65, monocyte chemoattractant protein-1 (mcp-1), and tumor necrosis factor α (tnf-α). |
2015-05-19 |
2023-08-13 |
rat |
| Noura Al-Jameil, Farah A Khan, Sadia Arjumand, Mohammad F Khan, Hajera Tabassu. Associated liver enzymes with hyperlipidemic profile in type 2 diabetes patients. International journal of clinical and experimental pathology. vol 7. issue 7. 2015-05-14. PMID:25120819. |
various biochemical parameters like fasting glucose, post prandial glucose, hba1c, total cholesterol (tc), triglycerides (tg), high density lipoprotein cholesterol (hdl-c), alanine amino transferase (alt), aspartate amino transferase (ast) and gamma-glutamyl transferase (ggt) were analyzed by roche module cobas 6000 (c501 & c601) analyzer, kits were procured by roche diagnostics. |
2015-05-14 |
2023-08-13 |
human |
| Tingting Xu, Lingli Zheng, Lina Xu, Lianhong Yin, Yan Qi, Youwei Xu, Xu Han, Jinyong Pen. Protective effects of dioscin against alcohol-induced liver injury. Archives of toxicology. vol 88. issue 3. 2015-05-12. PMID:24146112. |
in the present paper, ethanol-induced acute and chronic liver damage rat models were used, and the results showed that dioscin significantly alleviated liver steatosis, reduced the levels of alanine aminotransferase, aspartate aminotransferase, total triglyceride (tg), total cholesterol and malondialdehyde, and increased the levels of high-density lipoprotein, superoxide dismutase, glutathione and glutathione peroxidase. |
2015-05-12 |
2023-08-12 |
rat |
| Xi Zhao, Jie Xue, Xiao-Li Wang, Yan Zhang, Min Deng, Mei-Lin Xi. Involvement of hepatic peroxisome proliferator-activated receptor α/γ in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats. International immunopharmacology. vol 22. issue 1. 2015-05-11. PMID:24993341. |
the results showed that after treatment with osthole, the serum alanine aminotransferase, aspartate aminotransferase, total cholesterol, triglyceride (tg), and free fatty acid (ffa) levels, the hepatic tg, ffa, tumor necrosis factor-α, monocyte chemotactic protein-1, interleukin-6, and interleukin-8 contents, and the hepatic weight and liver index were lowered, especially in the osthole 20 mg/kg group. |
2015-05-11 |
2023-08-13 |
rat |
| Ali Akbar Malekirad, Mahya Faghih, Mansuoreh Mirabdollahi, Mahdi Kiani, Arezoo Fathi, Mohammad Abdollah. Neurocognitive, mental health, and glucose disorders in farmers exposed to organophosphorus pesticides. Arhiv za higijenu rada i toksikologiju. vol 64. issue 1. 2015-04-13. PMID:23705196. |
the subjects were also tested for fasting blood glucose (fbg), blood urea nitrogen (bun), cholesterol (cl), triglycerides (tg), creatinine, oral glucose tolerance test (gtt), high-density lipoprotein (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2015-04-13 |
2023-08-12 |
human |
| Min Pang, Shujian He, Lu Wang, Xinmin Cao, Lili Cao, Shaotong Jian. Physicochemical properties, antioxidant activities and protective effect against acute ethanol-induced hepatic injury in mice of foxtail millet (Setaria italica) bran oil. Food & function. vol 5. issue 8. 2015-03-30. PMID:24909671. |
in this, intragastric administration with different dosages of fmbo in mice ahead of acute ethanol administration could observably antagonize the ethanol-induced increases in serum alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), and the hepatic malondialdehyde (mda) levels, respectively, along with enhanced hepatic superoxide dismutase (sod) levels relative to the control. |
2015-03-30 |
2023-08-13 |
mouse |
| Mohd Nazri Abu, Suhana Samat, Norathirah Kamarapani, Fuzina Nor Hussein, Wan Iryani Wan Ismail, Hamzah Fansuri Hassa. Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-03-30. PMID:25821506. |
results showed that t. crispa significantly (p < 0.05) reduced the body weight (41.14 ± 1.40%), adiposity index serum levels (4.910 ± 0.80%), aspartate aminotransferase (ast: 161 ± 4.71 u/l), alanine aminotransferase (alt: 100.95 ± 3.10 u/l), total cholesterol (tc: 18.55 ± 0.26 mmol/l), triglycerides (tg: 3.70 ± 0.11 mmol/l), blood glucose (8.50 ± 0.30 mmo/l), resistin (0.74 ± 0.20 ng/ml), and leptin (17.428 ± 1.50 ng/ml) hormones in hfdtc group. |
2015-03-30 |
2023-08-13 |
rat |
| You-gui Li, Dong-feng Ji, Shi Zhong, Tian-bao Lin, Zhi-qiang L. Hypoglycemic effect of deoxynojirimycin-polysaccharide on high fat diet and streptozotocin-induced diabetic mice via regulation of hepatic glucose metabolism. Chemico-biological interactions. vol 225. 2015-02-23. PMID:25446853. |
for 90 d, significant decline in blood glucose, pyruvate, triglyceride (tg), aspartate transaminase (ast), alanine transaminase (alt), creatinine (cr), lipid peroxide (lpo) and malondialdehyde (mda) levels as well as evident increases in high density lipoprotein (hdl-c) and hepatic glycogen concentrations were observed. |
2015-02-23 |
2023-08-13 |
mouse |
| Seung Jun Kwack, Kyung Sik Yoon, Seong Kwang Lim, Hyo-Min Gwak, Ji Yun Kim, Yoon Mi Um, Jung Dae Lee, Ji Hyeon Hyeon, Yeon Joo Kim, Hyung Sik Kim, Byung-Mu Le. A one-generation reproductive toxicity study of 3,4-methylenedioxy-n-methamphetamine (MDMA, Ecstasy), an amphetamine derivative, in C57BL/6 mice. Journal of toxicology and environmental health. Part A. vol 77. issue 22-24. 2014-12-22. PMID:25343292. |
nonetheless, serum biochemistry markers showed that levels of alkaline phosphatase (alp), aspartate aminotransferase (ast), and blood urea nitrogen (bun) were markedly elevated in a dose-dependent manner from 5 mg and higher mdma/kg b.w., whereas levels of triglycerides (tg), potassium (k), and uric acid (ua) were reduced. |
2014-12-22 |
2023-08-13 |
mouse |
| Aree Thinkratok, Parin Suwannaprapha, Rungrudee Srisawa. Safety assessment of hydroethanolic rambutan rind extract: acute and sub-chronic toxicity studies. Indian journal of experimental biology. vol 52. issue 10. 2014-12-04. PMID:25345248. |
in acute toxicity study, all the studied doses of rre did not alter serum levels of triglyceride (tg), aspartate aminotransferase (ast) andalanine aminotransferase (alt). |
2014-12-04 |
2023-08-13 |
rat |
| In-Young Choi, Phil Lee, Wen-Tung Wang, Dongwei Hui, Xinkun Wang, William M Brooks, Elias K Michaeli. Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice. Neurochemical research. vol 39. issue 3. 2014-11-06. PMID:24442550. |
significant differences between adult tg and wt were higher glu, n-acetyl aspartate (naa), and naa + naa-glu (naag) levels, and lower lactate in the tg hippocampus and striatum than those of wt. |
2014-11-06 |
2023-08-12 |
mouse |
| Xiaokun Pei, Wei Wang, Ningshu Miao, Mengxin Xu, Chunlei Zhang, Mengmeng Sun, Mingbo Xu, Zhifeng Li. The protective effects of the combination of sodium ferulate and oxymatrine on ethanol-induced liver damage in mice. Environmental toxicology and pharmacology. vol 37. issue 1. 2014-10-28. PMID:24441025. |
the animal liver wet/dry weight (w/d) ratio and liver tissue histopathology, alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), malondialdehyde (mda), superoxidase dismutase (sod), c-reactive protein (crp), interleukin-6 (il-6), and nuclear factor κb (nf-κb) levels were measured. |
2014-10-28 |
2023-08-12 |
mouse |
| M Muthumani, S Milton Prab. Silibinin potentially attenuates arsenic-induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats. Cardiovascular toxicology. vol 14. issue 1. 2014-10-27. PMID:24062023. |
creatine kinase-mb, lactate dehydrogenase, aspartate transaminase, alanine transaminase and alkaline phosphatase, oxidative stress markers in heart, plasma total cholesterol (tc), triglycerides (tg), phospholipids (pl), free fatty acids (ffa), low density lipoprotein cholesterol, very low density lipoprotein cholesterol as well as cardiac lipid profile (tc, tg and ffa) and significantly (p < 0.05) decreased the level of serum high density lipoprotein cholesterol, cardiac pl, mitochondrial enzymes such as icdh, sdh, mdh, α-kdh and nadh dehydrogenase, levels of enzymatic antioxidant, nonenzymatic antioxidants and membrane-bound atpases in heart. |
2014-10-27 |
2023-08-12 |
rat |