| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Aree Thinkratok, Parin Suwannaprapha, Rungrudee Srisawa. Safety assessment of hydroethanolic rambutan rind extract: acute and sub-chronic toxicity studies. Indian journal of experimental biology. vol 52. issue 10. 2014-12-04. PMID:25345248. |
in acute toxicity study, all the studied doses of rre did not alter serum levels of triglyceride (tg), aspartate aminotransferase (ast) andalanine aminotransferase (alt). |
2014-12-04 |
2023-08-13 |
rat |
| In-Young Choi, Phil Lee, Wen-Tung Wang, Dongwei Hui, Xinkun Wang, William M Brooks, Elias K Michaeli. Metabolism changes during aging in the hippocampus and striatum of glud1 (glutamate dehydrogenase 1) transgenic mice. Neurochemical research. vol 39. issue 3. 2014-11-06. PMID:24442550. |
significant differences between adult tg and wt were higher glu, n-acetyl aspartate (naa), and naa + naa-glu (naag) levels, and lower lactate in the tg hippocampus and striatum than those of wt. |
2014-11-06 |
2023-08-12 |
mouse |
| Xiaokun Pei, Wei Wang, Ningshu Miao, Mengxin Xu, Chunlei Zhang, Mengmeng Sun, Mingbo Xu, Zhifeng Li. The protective effects of the combination of sodium ferulate and oxymatrine on ethanol-induced liver damage in mice. Environmental toxicology and pharmacology. vol 37. issue 1. 2014-10-28. PMID:24441025. |
the animal liver wet/dry weight (w/d) ratio and liver tissue histopathology, alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), malondialdehyde (mda), superoxidase dismutase (sod), c-reactive protein (crp), interleukin-6 (il-6), and nuclear factor κb (nf-κb) levels were measured. |
2014-10-28 |
2023-08-12 |
mouse |
| M Muthumani, S Milton Prab. Silibinin potentially attenuates arsenic-induced oxidative stress mediated cardiotoxicity and dyslipidemia in rats. Cardiovascular toxicology. vol 14. issue 1. 2014-10-27. PMID:24062023. |
creatine kinase-mb, lactate dehydrogenase, aspartate transaminase, alanine transaminase and alkaline phosphatase, oxidative stress markers in heart, plasma total cholesterol (tc), triglycerides (tg), phospholipids (pl), free fatty acids (ffa), low density lipoprotein cholesterol, very low density lipoprotein cholesterol as well as cardiac lipid profile (tc, tg and ffa) and significantly (p < 0.05) decreased the level of serum high density lipoprotein cholesterol, cardiac pl, mitochondrial enzymes such as icdh, sdh, mdh, α-kdh and nadh dehydrogenase, levels of enzymatic antioxidant, nonenzymatic antioxidants and membrane-bound atpases in heart. |
2014-10-27 |
2023-08-12 |
rat |
| Namasivayam Subhapradha, Ramachandran Saravanan, Pasiyappazham Ramasamy, Alagiri Srinivasan, Vairamani Shanmugam, Annaian Shanmuga. Hepatoprotective effect of β-chitosan from gladius of Sepioteuthis lessoniana against carbon tetrachloride-induced oxidative stress in Wistar rats. Applied biochemistry and biotechnology. vol 172. issue 1. 2014-10-07. PMID:24043453. |
the rats that received β-chitosan along with the administration of ccl4 showed significantly decreased plasma and tissue alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities and total cholesterol, triglyceride (tg) and free fatty acid (ffa) contents, whereas the treatment with β-chitosan alone markedly increased rat hepatic and circulatory superoxide dismutase (sod), catalase and glutathione peroxidase (gpx) and reduced glutathione (gsh) levels and decreased the malondialdehyde level. |
2014-10-07 |
2023-08-12 |
rat |
| Hyoung Joon Park, Soo-Jung Lee, Yuno Song, Sun-Hee Jang, Yeoung-Gyu Ko, Suk Nam Kang, Byung Yeoup Chung, Hong-Duck Kim, Gon-Sup Kim, Jae-Hyeon Ch. Schisandra chinensis prevents alcohol-induced fatty liver disease in rats. Journal of medicinal food. vol 17. issue 1. 2014-09-02. PMID:24456360. |
ethanol treatment resulted in a significant increase in alanine aminotransferase, aspartate aminotransferase, and hepatic triglyceride (tg) levels and caused fatty degeneration of liver. |
2014-09-02 |
2023-08-12 |
rat |
| Amr M Abbas, Hussein F Sak. Simvastatin and vitamin E effects on cardiac and hepatic oxidative stress in rats fed on high fat diet. Journal of physiology and biochemistry. vol 69. issue 4. 2014-07-17. PMID:23580160. |
in all rats, serum vitamin e, total cholesterol (tc), triglycerides (tg), low (ldl) and high (hdl) density lipoproteins, alanine (alt) and aspartate (ast) transaminases, alkaline phosphatase (alp), and gamma glutamyl transpeptidase (ggt) as well as cardiac and hepatic thiobarbituric acid-reactive substances (tbars) and antioxidants (reduced glutathione (gsh), superoxide dismutase (sod), and catalase (cat)) were measured. |
2014-07-17 |
2023-08-12 |
rat |
| H-J Park, J-M Han, H-G Kim, M-K Choi, J-S Lee, H-W Lee, C-G So. Chunggan extract (CGX), methionine-and choline-deficient (MCD) diet-induced hepatosteatosis and oxidative stress in C57BL/6 mice. Human & experimental toxicology. vol 32. issue 12. 2014-07-15. PMID:23970447. |
cgx treatment significantly attenuated these alterations in the serum levels including triglyceride (tg), aspartate aminotransferase, alanine aminotransferase, alkaline phosphatase, and total bilirubin. |
2014-07-15 |
2023-08-12 |
mouse |
| Ruijun Zhang, Yan Zhao, Yanfei Sun, Xinshan Lu, Xingbin Yan. Isolation, characterization, and hepatoprotective effects of the raffinose family oligosaccharides from Rehmannia glutinosa Libosch. Journal of agricultural and food chemistry. vol 61. issue 32. 2014-07-07. PMID:23879777. |
administration of rgos orally daily in mice for 21 days significantly reduced the impact of ccl4 toxicity on the serum markers of liver damage, serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total-cholesterol (tc), and triglycerides (tg). |
2014-07-07 |
2023-08-12 |
mouse |
| Ching-Shu Lai, Min-Hau Ho, Mei-Ling Tsai, Shiming Li, Vladimir Badmaev, Chi-Tang Ho, Min-Hsiung Pa. Suppression of adipogenesis and obesity in high-fat induced mouse model by hydroxylated polymethoxyflavones. Journal of agricultural and food chemistry. vol 61. issue 43. 2014-06-12. PMID:24089698. |
administration of hpmfs reduced serum levels of aspartate aminotransferase (got), alanine aminotransferase (gpt), triglycerides (tg), and total cholesterol (t-cho). |
2014-06-12 |
2023-08-12 |
mouse |
| Gabriel Lima-Oliveira, Giuseppe Lippi, Gian Luca Salvagno, Elisa Danese, Martina Montagnana, Giorgio Brocco, Monica Voi, Geraldo Picheth, Gian Cesare Guid. Does laboratory automation for the preanalytical phase improve data quality? Journal of laboratory automation. vol 18. issue 5. 2014-04-02. PMID:23686657. |
significant increases were observed in g1 compared with g2 samples as follows: (1) before storage for alkaline phosphatase (alp), lactate dehydrogenase (ldh), phosphate (p), magnesium (mg), iron (fe), and hemolysis index and (2) after storage for total cholesterol (col), triglycerides (tg), total protein (tp), albumin (alb), blood urea nitrogen (bun), creatinine (cre), uric acid (ua), alp, pancreatic amylase, aspartate aminotransferase (ast), alanine aminotransferase (alt), g-glutamyltransferase (ggt), ldh, creatine kinase (ck), calcium (ca), fe, sodium (na), potassium (k), and hemolysis index. |
2014-04-02 |
2023-08-12 |
human |
| B E Oyinloye, S O Nwozo, G H Amah, A O Awoyinka, O A Ojo, B O Ajiboye, H A Tijan. Prophylactic effect of aqueous extract of Sesamum indicum seeds on ethanol-induced toxicity in male rats. Nutrition research and practice. vol 8. issue 1. 2014-03-10. PMID:24611106. |
lipid peroxidation (tbars) and reduced glutathione (gsh) levels and catalase (cat), glutathione peroxidase (gpx), superoxide dismutase (sod) and gluthathione-s-transferase (gst) activities were then determined in the liver, serum triglyceride (tg) levels, alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities were monitored and histological examination was carried out. |
2014-03-10 |
2023-08-12 |
rat |
| Oluwatosin Adekunle Adaramoye, Olubukola Oyebimpe Akann. Effects of Methanol Extract of Breadfruit (Artocarpus altilis) on Atherogenic Indices and Redox Status of Cellular System of Hypercholesterolemic Male Rats. Advances in pharmacological sciences. vol 2014. 2014-03-04. PMID:24592277. |
biochemical indices such as total cholesterol (tc), triglycerides (tg), low- and high-density lipoproteins-cholesterol (ldl-c and hdl-c), aspartate and alanine aminotransferases (ast and alt), lactate dehydrogenase (ldh), reduced glutathione, glutathione-s-transferase, glutathione peroxidase (gpx), catalase (cat), superoxide dismutase (sod), and lipid peroxidation (lpo) were assessed. |
2014-03-04 |
2023-08-12 |
rat |
| Ya-Ling Chen, Hsiang-Chi Peng, Shan-Wen Tan, Cheng-Yuh Tsai, Yi-Huei Huang, Hao-Yu Wu, Suh-Ching Yan. Amelioration of ethanol-induced liver injury in rats by nanogold flakes. Alcohol (Fayetteville, N.Y.). vol 47. issue 6. 2014-02-24. PMID:23830375. |
after 10 weeks, rats in group e showed significantly higher plasma aspartate transaminase (ast) and alanine transaminase (alt) activities than those in group c. a significantly increased concentration of hepatic triglyceride (tg) was found in group e. furthermore, higher hepatic glutathione reductase (grd), superoxide dismutase (sod), and catalase (cat) activities together with higher tumor necrosis factor (tnf)-α concentration and higher hepatic cytochrome (cyp2e1) protein expression were also observed in group e. in contrast, the hepatic tg concentration in group ehf was significantly lower than that of group e. in addition, hepatic glutathione peroxidase (gpx), sod, and cat activities together with tnf-α concentration and hepatic cyp2e1 protein expression in group ehf were significantly lower than those in group e. we concluded that nanogold flakes might ameliorate alcohol-induced liver injury by maintaining the hepatic antioxidative status. |
2014-02-24 |
2023-08-12 |
rat |
| Hassan Ahmadvand, Majid Tavafi, Ali Reza Khalatbar. Hepatoprotective and Hypolipidemic Effects of Satureja Khuzestanica Essential Oil in Alloxan-induced Type 1 Diabetic Rats. Iranian journal of pharmaceutical research : IJPR. vol 11. issue 4. 2013-11-19. PMID:24250556. |
after 8 weeks, the levels of fasting blood glucose (fbg), triglyceride (tg), cholesterol (c), low density lipoprotein (ldl), very low density lipoprotein (vldl), high density lipoprotein (hdl), atherogenic index and the activities of alanine aminotransferase (alt), aspartate aminotransferase (ast) and alkaline phosphatase (alp) of all groups were analyzed. |
2013-11-19 |
2023-08-12 |
rat |
| Hossein Ashraf, Reza Heidari, Vahid Nejati, Minoo Ilkhanipoo. Effects of Aqueous Extract of Berberis integerrima Root on Some Physiological Parameters in Streptozotocin-Induced Diabetic Rats. Iranian journal of pharmaceutical research : IJPR. vol 12. issue 2. 2013-11-19. PMID:24250618. |
stz-induced diabetic rats showed significant increases in the levels of blood glucose, triglycerides (tg), total cholesterol (tc), low density lipoprotein ldl-cholesterol (ldl-c), creatinine (cr), urea, alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), total bilirubin while body weight, high density lipoprotein hdl-cholesterol (hdl-c) and total protein levels were significantly decreased compared to normal rats. |
2013-11-19 |
2023-08-12 |
rat |
| Wei Zhang, Rutao Hong, Tulei Tia. Silymarin's Protective Effects and Possible Mechanisms on Alcoholic Fatty Liver for Rats. Biomolecules & therapeutics. vol 21. issue 4. 2013-11-18. PMID:24244810. |
the activities of alanine transarninase (alt) and aspartate aminotransferase (ast), the levels of total bilirubin (tbil), total cholesterol (tc) and triglyceride (tg) in serum were detected with routine laboratory methods using an autoanalyzer. |
2013-11-18 |
2023-08-12 |
rat |
| Noha Ahmed El Boghdad. Antioxidant and antiapoptotic effects of proanthocyanidin and ginkgo biloba extract against doxorubicin-induced cardiac injury in rats. Cell biochemistry and function. vol 31. issue 4. 2013-10-21. PMID:23112126. |
dox-induced cardiotoxicity was evidenced by a significant increase in serum aspartate transaminase (ast), creatine phosphokinase isoenzyme (ck-mb), lactate dehydrogenase (ldh), total cholesterol (tc) and triglyceride (tg) activities and levels. |
2013-10-21 |
2023-08-12 |
rat |
| Dong Wook Lim, Mikyung Song, Juyeon Park, Sang Woug Park, Nak Hoon Kim, Bhakta Prasad Gaire, Ho-Young Choi, Hocheol Ki. Anti-obesity effect of HT048, a herbal combination, in high fat diet-induced obese rats. Molecules (Basel, Switzerland). vol 17. issue 12. 2013-10-18. PMID:23519251. |
we measured the food intake, body weight, epididymal adipose tissue and liver weights, and serum total cholesterol (tc), triglyceride (tg), alanine transaminase (alt), and aspartate aminotransferase (ast) levels. |
2013-10-18 |
2023-08-12 |
rat |
| Hamidah Mohd Yusof, Norlaily Mohd Ali, Swee Keong Yeap, Wan Yong Ho, Boon Kee Beh, Soo Peng Koh, Kamariah Long, Suraini Abdul Aziz, Noorjahan Banu Alithee. Hepatoprotective Effect of Fermented Soybean (Nutrient Enriched Soybean Tempeh) against Alcohol-Induced Liver Damage in Mice. Evidence-based complementary and alternative medicine : eCAM. vol 2013. 2013-09-23. PMID:24058369. |
the evaluation of histological sections, serum biochemical markers (aspartate aminotransferase (ast), alanine aminotransferase (alt), and cholesterol and triglycerides (tg)), liver immune response level (nitric oxide (no)) and liver antioxidant level (superoxide dismutase (sod), ferric reducing antioxidant power (frap), and malondialdehyde (mda)) was conducted in order to compare the effects of nonfermented soybean extract (sbe) and fermented soybean extract (neste) on alcohol-induced liver damage in mice. |
2013-09-23 |
2023-08-12 |
mouse |