| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Jianjun Guo, Yonghong Meng, Yan Zhao, Yuanyuan Hu, Daoyuan Ren, Xingbin Yan. Myricetin derived from Hovenia dulcis Thunb. ameliorates vascular endothelial dysfunction and liver injury in high choline-fed mice. Food & function. vol 6. issue 5. 2016-02-05. PMID:25881982. |
furthermore, continuous administration of myr at 400 and 800 mg per kg bw in choline-fed mice could significantly decrease the high choline diet-induced elevation of serum total cholesterol (tc), total triglyceride (tg), low density lipoprotein-cholesterol (ldl-c), endothelin 1 (et-1) and thromboxane a2 (txa2) levels as well as alanine aminotransferase (alt) and aspartate aminotransferase (ast) activities, while the choline-induced decline of serum high density lipoprotein-cholesterol (hdl-c), endothelin nitric oxide synthase (enos), nitric oxide (no) and prostaglandin i2 (pgi2) levels could be markedly elevated in mice (p < 0.05, p < 0.01). |
2016-02-05 |
2023-08-13 |
mouse |
| Shuang Xu, Jin-Feng Hu, Shi-Feng Chu, Ning Han, Jing-Wei Li, Yue-Ting Li, Nai-Hong Che. [Oil of Piper longum unsaponifiable matter prevents cholesterol gallstone formation]. Yao xue xue bao = Acta pharmaceutica Sinica. vol 48. issue 7. 2016-02-02. PMID:24133988. |
the results showed that serum tc, tg (triglycerides) and ast (aspartate transaminase) contents, gallbladder cholesterol crystallization and csi increased significantly (p < 0.05). |
2016-02-02 |
2023-08-12 |
mouse |
| Meng Wang, Jianguo Sun, Zhihui Jiang, Wenyan Xie, Xiaoying Zhan. Hepatoprotective effect of kaempferol against alcoholic liver injury in mice. The American journal of Chinese medicine. vol 43. issue 2. 2016-01-14. PMID:25787296. |
the liver functions were observed by monitoring the following parameters: aspartate aminotransferase (ast/got) and alanine aminotransferase (alt/gpt) levels in serum; histopathological studies of liver tissue; oxidative stress by hydrogen peroxide (h2o2), superoxide dismutase (sod) and glutathione (gsh); the lipid peroxidation status by malondialdehyde (mda) and lipid accumulation by triglyceride (tg) level in serum; and the expression levels and activities of a key microsomal enzyme cytochrome 2e1 (cyp2e1), by both in vitro and in vivo methods. |
2016-01-14 |
2023-08-13 |
mouse |
| Jai-Jen Tsai, Hsing-Chun Kuo, Kam-Fai Lee, Tung-Hu Tsa. Glycyrrhizin represses total parenteral nutrition-associated acute liver injury in rats by suppressing endoplasmic reticulum stress. International journal of molecular sciences. vol 14. issue 6. 2015-10-15. PMID:23771023. |
we found that aspartate aminotransferase (ast), alanine aminotransferase (alt), total bilirubin (tb) and triglyceride (tg) levels were significantly increased in the tpn group without glycyrrhizin pretreatment and decreased in the glycyrrhizin-pretreated tpn group in a dose-dependent manner. |
2015-10-15 |
2023-08-12 |
rat |
| b' Okan K\\xc4\\xb1z\\xc4\\xb1lyel, Mahmut S Metin, \\xc3\\x96mer F Elmas, Yasemin \\xc3\\x87ay\\xc4\\xb1r, Ak\\xc4\\xb1n Akta\\xc5\\x9. Effects of oral isotretinoin on lipids and liver enzymes in acne patients. Cutis. vol 94. issue 5. 2015-09-28. PMID:25474452.' |
each patient's medical records were evaluated to determine baseline triglyceride (tg), low-density lipoprotein (ldl), high-density lipoprotein (hdl), aspartate aminotransferase (ast), and alanine aminotransferase (alt) levels compared to levels recorded at 3 and 6 months following initiation of treatment with oral isotretinoin. |
2015-09-28 |
2023-08-13 |
Not clear |
| Wei Li, Xin-Nan Qu, Ye Han, Si-Wen Zheng, Jia Wang, Ying-Ping Wan. Ameliorative effects of 5-hydroxymethyl-2-furfural (5-HMF) from Schisandra chinensis on alcoholic liver oxidative injury in mice. International journal of molecular sciences. vol 16. issue 2. 2015-09-25. PMID:25622257. |
our results showed that the activities of alt (alanine aminotransferase), ast (aspartate transaminase), tc (total cholesterol), tg (triglyceride), l-dlc (low density lipoprotein) in serum and the levels of mda (malondialdehyde) in liver tissue, decreased significantly (p < 0.05) in the 5-hmf-treated group compared with the alcohol group. |
2015-09-25 |
2023-08-13 |
mouse |
| Ye Han, Qi Xu, Jiang-ning Hu, Xin-yue Han, Wei Li, Li-chun Zha. Maltol, a food flavoring agent, attenuates acute alcohol-induced oxidative damage in mice. Nutrients. vol 7. issue 1. 2015-09-24. PMID:25608939. |
for hepatoprotective activity in vivo, pretreatment with maltol (12.5, 25 and 50 mg/kg; 15 days) drastically prevented the elevated activities of aspartate transaminase (ast), alanine transaminase (alt), alkaline phosphatase (alp) and triglyceride (tg) in serum and the levels of malondialdehyde (mda), tumor necrosis factor-α (tnf-α), interleukin-1β (il-1β) in liver tissue (p < 0.05). |
2015-09-24 |
2023-08-13 |
mouse |
| Maria Bogdan, Isabela Silosi, Petra Surlin, Andrei Adrian Tica, Oana Sorina Tica, Tudor-Adrian Balseanu, Anne-Marie Rauten, Adrian Came. Salivary and serum biomarkers for the study of side effects of aripiprazole coprescribed with mirtazapine in rats. International journal of clinical and experimental medicine. vol 8. issue 5. 2015-07-29. PMID:26221370. |
also, serum levels for total cholesterol (tc), low and high-density lipoprotein (ldl, hdl), triglycerides (tg), aspartate aminotransferase (asat) and alanine amino transferase (alat) were assessed. |
2015-07-29 |
2023-08-13 |
rat |
| Adejuwon Adewale Adeneye, Olufunsho Awodele, Sheriff Aboyade Aiyeola, Adokiye Senibo Beneb. Modulatory potentials of the aqueous stem bark extract of Mangifera indica on carbon tetrachloride-induced hepatotoxicity in rats. Journal of traditional and complementary medicine. vol 5. issue 2. 2015-07-07. PMID:26151020. |
the serum levels of alanine aminotransferase (alt), aspartate aminotransferase (ast), alkaline phosphatase (alp), total protein (tp), albumin (alb), triglyceride (tg), total cholesterol (tc), high density lipoprotein cholesterol (hdl-c), low density lipoprotein cholesterol (ldl-c), total bilirubin (tb), conjugated bilirubin (cb) and fasting blood glucose (fbg) levels were estimated. |
2015-07-07 |
2023-08-13 |
rat |
| Zafar Iqbal, Zia ur Rahman, Faqir Muhammad, Masood Akhtar, Mian Muhammad Awais, Tanweer Khaliq, Amar Nasir, Muhammad Nadeem, Kinza Khan, Hafiz Muhammad Arshad, Muhammad Abdul Basi. Effect of oxytocin on serum biochemistry, liver enzymes, and metabolic hormones in lactating Nili Ravi buffaloes. Tropical animal health and production. vol 47. issue 1. 2015-06-30. PMID:25281211. |
serum biochemical profile including glucose, total cholesterol (tchol), high-density lipoprotein cholesterol (hdl-c), low-density lipoprotein cholesterol (ldl-c), triglycerides (tg), total proteins (tp), c-reactive protein (crp), liver enzymes aspartate transaminase (ast), alanine transaminase (alt), and metabolic hormones triiodothyronine (t₃) and thyroxine (t₄) were studied. |
2015-06-30 |
2023-08-13 |
Not clear |
| Md Mahbubur Rahman, Sei-Jin Lee, A-Reum Mun, Gareeballah Osman Adam, Ra-Mi Park, Gi-Beum Kim, Hyung-Sub Kang, Jin-Shang Kim, Shang-Jin Kim, Sung-Zoo Ki. Relationships between blood Mg2+ and energy metabolites/enzymes after acute exhaustive swimming exercise in rats. Biological trace element research. vol 161. issue 1. 2015-06-22. PMID:25035192. |
after aese, blood mg(2+), tmg, k(+), partial pressure of carbon dioxide, lactate, total protein (t-pro), high-density lipoprotein (hdl), creatinine (cre), blood urea nitrogen (bun), uric acid (ua), alanine aminotransferase (alt), aspartate aminotransferase (ast), alanine phosphatase (alp), lactate dehydrogenase (ldh), and creatinine kinase (ck) were significantly increased, whereas ph, partial pressure of oxygen, oxygen saturation, the mg(2+)/tmg and ca(2+)/mg(2+) ratios, hco3 (-), glucose, triglyceride (tg), and low-density lipoprotein (ldl) were significantly decreased. |
2015-06-22 |
2023-08-13 |
rat |
| Zhiguo Wang, Bo Su, Sumei Fan, Haixia Fei, Wei Zha. Protective effect of oligomeric proanthocyanidins against alcohol-induced liver steatosis and injury in mice. Biochemical and biophysical research communications. vol 458. issue 4. 2015-05-26. PMID:25680468. |
the results showed that opc significantly improved alcohol-induced dyslipidemia and alleviated liver steatosis by reducing levels of serum alanine aminotransferase (alt), aspartate aminotransferase (ast), total triglyceride (tg), total cholesterol (tc), low-density cholesterol (ldl-c) and liver malondialdehyde (mda), and increasing levels of serum high-density lipoprotein (hdl-c), liver superoxide dismutase (sod). |
2015-05-26 |
2023-08-13 |
mouse |
| Yonghui Yin, Fanghua Qi, Zhenhua Song, Bo Zhang, Jialin Ten. Ferulic acid combined with astragaloside IV protects against vascular endothelial dysfunction in diabetic rats. Bioscience trends. vol 8. issue 4. 2015-05-19. PMID:25224628. |
blood samples were collected to measure levels of hemoglobin a1c (hbalc), triglyceride (tg), total cholesterol (tc), low density lipoprotein cholesterol (ldl-c), low density lipoproteins (ox-ldl), alanine aminotransferase (alt), aspartate aminotransferase (ast) and creatinine (cr), nitric oxide (no) and endothelial nitric oxide synthase (enos), and abdominal aorta tissue samples were collected for observing histological morphology changes of endothelium and detecting gene and protein expression of nuclear factor-κb (nf-κb) p65, monocyte chemoattractant protein-1 (mcp-1), and tumor necrosis factor α (tnf-α). |
2015-05-19 |
2023-08-13 |
rat |
| Noura Al-Jameil, Farah A Khan, Sadia Arjumand, Mohammad F Khan, Hajera Tabassu. Associated liver enzymes with hyperlipidemic profile in type 2 diabetes patients. International journal of clinical and experimental pathology. vol 7. issue 7. 2015-05-14. PMID:25120819. |
various biochemical parameters like fasting glucose, post prandial glucose, hba1c, total cholesterol (tc), triglycerides (tg), high density lipoprotein cholesterol (hdl-c), alanine amino transferase (alt), aspartate amino transferase (ast) and gamma-glutamyl transferase (ggt) were analyzed by roche module cobas 6000 (c501 & c601) analyzer, kits were procured by roche diagnostics. |
2015-05-14 |
2023-08-13 |
human |
| Tingting Xu, Lingli Zheng, Lina Xu, Lianhong Yin, Yan Qi, Youwei Xu, Xu Han, Jinyong Pen. Protective effects of dioscin against alcohol-induced liver injury. Archives of toxicology. vol 88. issue 3. 2015-05-12. PMID:24146112. |
in the present paper, ethanol-induced acute and chronic liver damage rat models were used, and the results showed that dioscin significantly alleviated liver steatosis, reduced the levels of alanine aminotransferase, aspartate aminotransferase, total triglyceride (tg), total cholesterol and malondialdehyde, and increased the levels of high-density lipoprotein, superoxide dismutase, glutathione and glutathione peroxidase. |
2015-05-12 |
2023-08-12 |
rat |
| Xi Zhao, Jie Xue, Xiao-Li Wang, Yan Zhang, Min Deng, Mei-Lin Xi. Involvement of hepatic peroxisome proliferator-activated receptor α/γ in the therapeutic effect of osthole on high-fat and high-sucrose-induced steatohepatitis in rats. International immunopharmacology. vol 22. issue 1. 2015-05-11. PMID:24993341. |
the results showed that after treatment with osthole, the serum alanine aminotransferase, aspartate aminotransferase, total cholesterol, triglyceride (tg), and free fatty acid (ffa) levels, the hepatic tg, ffa, tumor necrosis factor-α, monocyte chemotactic protein-1, interleukin-6, and interleukin-8 contents, and the hepatic weight and liver index were lowered, especially in the osthole 20 mg/kg group. |
2015-05-11 |
2023-08-13 |
rat |
| Ali Akbar Malekirad, Mahya Faghih, Mansuoreh Mirabdollahi, Mahdi Kiani, Arezoo Fathi, Mohammad Abdollah. Neurocognitive, mental health, and glucose disorders in farmers exposed to organophosphorus pesticides. Arhiv za higijenu rada i toksikologiju. vol 64. issue 1. 2015-04-13. PMID:23705196. |
the subjects were also tested for fasting blood glucose (fbg), blood urea nitrogen (bun), cholesterol (cl), triglycerides (tg), creatinine, oral glucose tolerance test (gtt), high-density lipoprotein (hdl), aspartate aminotransferase (ast), alanine aminotransferase (alt), and alkaline phosphatase (alp). |
2015-04-13 |
2023-08-12 |
human |
| Min Pang, Shujian He, Lu Wang, Xinmin Cao, Lili Cao, Shaotong Jian. Physicochemical properties, antioxidant activities and protective effect against acute ethanol-induced hepatic injury in mice of foxtail millet (Setaria italica) bran oil. Food & function. vol 5. issue 8. 2015-03-30. PMID:24909671. |
in this, intragastric administration with different dosages of fmbo in mice ahead of acute ethanol administration could observably antagonize the ethanol-induced increases in serum alanine aminotransferase (alt), aspartate aminotransferase (ast), triglyceride (tg), and the hepatic malondialdehyde (mda) levels, respectively, along with enhanced hepatic superoxide dismutase (sod) levels relative to the control. |
2015-03-30 |
2023-08-13 |
mouse |
| Mohd Nazri Abu, Suhana Samat, Norathirah Kamarapani, Fuzina Nor Hussein, Wan Iryani Wan Ismail, Hamzah Fansuri Hassa. Tinospora crispa Ameliorates Insulin Resistance Induced by High Fat Diet in Wistar Rats. Evidence-based complementary and alternative medicine : eCAM. vol 2015. 2015-03-30. PMID:25821506. |
results showed that t. crispa significantly (p < 0.05) reduced the body weight (41.14 ± 1.40%), adiposity index serum levels (4.910 ± 0.80%), aspartate aminotransferase (ast: 161 ± 4.71 u/l), alanine aminotransferase (alt: 100.95 ± 3.10 u/l), total cholesterol (tc: 18.55 ± 0.26 mmol/l), triglycerides (tg: 3.70 ± 0.11 mmol/l), blood glucose (8.50 ± 0.30 mmo/l), resistin (0.74 ± 0.20 ng/ml), and leptin (17.428 ± 1.50 ng/ml) hormones in hfdtc group. |
2015-03-30 |
2023-08-13 |
rat |
| You-gui Li, Dong-feng Ji, Shi Zhong, Tian-bao Lin, Zhi-qiang L. Hypoglycemic effect of deoxynojirimycin-polysaccharide on high fat diet and streptozotocin-induced diabetic mice via regulation of hepatic glucose metabolism. Chemico-biological interactions. vol 225. 2015-02-23. PMID:25446853. |
for 90 d, significant decline in blood glucose, pyruvate, triglyceride (tg), aspartate transaminase (ast), alanine transaminase (alt), creatinine (cr), lipid peroxide (lpo) and malondialdehyde (mda) levels as well as evident increases in high density lipoprotein (hdl-c) and hepatic glycogen concentrations were observed. |
2015-02-23 |
2023-08-13 |
mouse |