| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| Krishna P L Bhat, Katrina L Salazar, Veerakumar Balasubramaniyan, Khalida Wani, Lindsey Heathcock, Faith Hollingsworth, Johanna D James, Joy Gumin, Kristin L Diefes, Se Hoon Kim, Alice Turski, Yasaman Azodi, Yuhui Yang, Tiffany Doucette, Howard Colman, Erik P Sulman, Frederick F Lang, Ganesh Rao, Sjef Copray, Brian D Vaillant, Kenneth D Aldap. The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes & development. vol 25. issue 24. 2012-02-02. PMID:22190458. |
the coexpression of taz, but not a mutated form of taz that lacks tead binding, with platelet-derived growth factor-b (pdgf-b) resulted in high-grade tumors with mes features in a murine model of glioma. |
2012-02-02 |
2023-08-12 |
Not clear |
| Krishna P L Bhat, Katrina L Salazar, Veerakumar Balasubramaniyan, Khalida Wani, Lindsey Heathcock, Faith Hollingsworth, Johanna D James, Joy Gumin, Kristin L Diefes, Se Hoon Kim, Alice Turski, Yasaman Azodi, Yuhui Yang, Tiffany Doucette, Howard Colman, Erik P Sulman, Frederick F Lang, Ganesh Rao, Sjef Copray, Brian D Vaillant, Kenneth D Aldap. The transcriptional coactivator TAZ regulates mesenchymal differentiation in malignant glioma. Genes & development. vol 25. issue 24. 2012-02-02. PMID:22190458. |
our studies uncover a direct role for taz and tead in driving the mes differentiation of malignant glioma. |
2012-02-02 |
2023-08-12 |
Not clear |
| Sandra Habbig, Malte P Bartram, Roman U Müller, Ricarda Schwarz, Nikolaos Andriopoulos, Shuhua Chen, Josef G Sägmüller, Martin Hoehne, Volker Burst, Max C Liebau, H Christian Reinhardt, Thomas Benzing, Bernhard Scherme. NPHP4, a cilia-associated protein, negatively regulates the Hippo pathway. The Journal of cell biology. vol 193. issue 4. 2011-07-21. PMID:21555462. |
moreover, nphp4 induced release from 14-3-3 binding and nuclear translocation of yap and taz, promoting tea domain (tead)/taz/yap-dependent transcriptional activity. |
2011-07-21 |
2023-08-12 |
drosophila_melanogaster |
| Dulcie Lai, King Ching Ho, Yawei Hao, Xiaolong Yan. Taxol resistance in breast cancer cells is mediated by the hippo pathway component TAZ and its downstream transcriptional targets Cyr61 and CTGF. Cancer research. vol 71. issue 7. 2011-07-11. PMID:21349946. |
interaction of taz with the tead family of transcription factors was essential for taz to activate the cyr61/ctgf promoters and to induce taxol resistance. |
2011-07-11 |
2023-08-12 |
human |
| Siew Wee Chan, Chun Jye Lim, Li Shen Loo, Yaan Fun Chong, Caixia Huang, Wanjin Hon. TEADs mediate nuclear retention of TAZ to promote oncogenic transformation. The Journal of biological chemistry. vol 284. issue 21. 2009-07-07. PMID:19324876. |
in this study, we show that taz interacts with tead transcriptional factors. |
2009-07-07 |
2023-08-12 |
Not clear |
| Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, Kun-Liang Gua. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of biological chemistry. vol 284. issue 20. 2009-06-30. PMID:19324877. |
tead transcription factors mediate the function of taz in cell growth and epithelial-mesenchymal transition. |
2009-06-30 |
2023-08-12 |
human |
| Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, Kun-Liang Gua. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of biological chemistry. vol 284. issue 20. 2009-06-30. PMID:19324877. |
we demonstrate here that tead is a key downstream transcription factor mediating the function of taz. |
2009-06-30 |
2023-08-12 |
human |
| Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, Kun-Liang Gua. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of biological chemistry. vol 284. issue 20. 2009-06-30. PMID:19324877. |
disruption of tead-taz binding or silencing of tead expression blocked the function of taz to promote cell proliferation and to induce epithelial-mesenchymal transition, demonstrating tead as a key downstream effector of taz. |
2009-06-30 |
2023-08-12 |
human |
| Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, Kun-Liang Gua. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of biological chemistry. vol 284. issue 20. 2009-06-30. PMID:19324877. |
we also identified ctgf, a gene that regulates cell adhesion, proliferation, and migration, as a direct target of taz and tead. |
2009-06-30 |
2023-08-12 |
human |
| Heng Zhang, Chen-Ying Liu, Zheng-Yu Zha, Bin Zhao, Jun Yao, Shimin Zhao, Yue Xiong, Qun-Ying Lei, Kun-Liang Gua. TEAD transcription factors mediate the function of TAZ in cell growth and epithelial-mesenchymal transition. The Journal of biological chemistry. vol 284. issue 20. 2009-06-30. PMID:19324877. |
our study establishes a functional partnership between taz and tead under negative regulation by the hippo signaling pathway. |
2009-06-30 |
2023-08-12 |
human |