| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Giustina, M Peracchi, E Reschini, E Panerai, M Pint. Dose-response study of the inhibiting effect of somatostatin on growth hormone and insulin secretion in normal subjects and acromegalic patients. Metabolism: clinical and experimental. vol 24. issue 7. 1975-09-09. PMID:1138156. |
dose-response study of the inhibiting effect of somatostatin on growth hormone and insulin secretion in normal subjects and acromegalic patients. |
1975-09-09 |
2023-08-11 |
human |
| G Giustina, M Peracchi, E Reschini, E Panerai, M Pint. Dose-response study of the inhibiting effect of somatostatin on growth hormone and insulin secretion in normal subjects and acromegalic patients. Metabolism: clinical and experimental. vol 24. issue 7. 1975-09-09. PMID:1138156. |
a dose-response study of the effect of somatostatin on plasma growth hormone (gh) and immunoreactive insulin (iri) levels was performed in normal subjects and acromegalic patients. |
1975-09-09 |
2023-08-11 |
human |
| G Giustina, M Peracchi, E Reschini, E Panerai, M Pint. Dose-response study of the inhibiting effect of somatostatin on growth hormone and insulin secretion in normal subjects and acromegalic patients. Metabolism: clinical and experimental. vol 24. issue 7. 1975-09-09. PMID:1138156. |
a dose of somatostatin inhibiting gh secretion without affecting insulin secretion has not been found either in acromegalics and in normals. |
1975-09-09 |
2023-08-11 |
human |
| M Lorenzi, J E Gerich, J H Karam, P H Forsha. Failure of somatostatin to inhibit tolbutamide-induced insulin secretion in patients with insulinomas: a possible diagnostic tool. The Journal of clinical endocrinology and metabolism. vol 40. issue 6. 1975-08-29. PMID:166088. |
failure of somatostatin to inhibit tolbutamide-induced insulin secretion in patients with insulinomas: a possible diagnostic tool. |
1975-08-29 |
2023-08-11 |
human |
| M Lorenzi, J E Gerich, J H Karam, P H Forsha. Failure of somatostatin to inhibit tolbutamide-induced insulin secretion in patients with insulinomas: a possible diagnostic tool. The Journal of clinical endocrinology and metabolism. vol 40. issue 6. 1975-08-29. PMID:166088. |
the effects of somatostatin on tolbutamide-stimulated insulin release were studied in 4 patients with insulin-producing tumors of the pancreas and in 6 normal subjects. |
1975-08-29 |
2023-08-11 |
human |
| M Lorenzi, J E Gerich, J H Karam, P H Forsha. Failure of somatostatin to inhibit tolbutamide-induced insulin secretion in patients with insulinomas: a possible diagnostic tool. The Journal of clinical endocrinology and metabolism. vol 40. issue 6. 1975-08-29. PMID:166088. |
in contrast to its effective inhibition of insulin release in normal subjects, somatostatin, without exception, failed to inhibit tolbutamide-induced insulin release in the patients with pancreatic beta-cell tumors. |
1975-08-29 |
2023-08-11 |
human |
| H Okamoto, Y Noto, S Miyamoto, H Mabuchi, R Taked. Inhibition by somatostatin of insulin release from isolated pancreatic islets. FEBS letters. vol 54. issue 1. 1975-08-22. PMID:165970. |
inhibition by somatostatin of insulin release from isolated pancreatic islets. |
1975-08-22 |
2023-08-11 |
Not clear |
| L Turcot-Lemay, A Lemay, P E Lac. Somatostatin inhibition of insulin release from freshly isolated and organ cultured rat islets of Langerhans in vitro. Biochemical and biophysical research communications. vol 63. issue 4. 1975-07-28. PMID:1093547. |
somatostatin inhibition of insulin release from freshly isolated and organ cultured rat islets of langerhans in vitro. |
1975-07-28 |
2023-08-11 |
rat |
| S E Christensen, A P Hansen, J Iversen, K Lundbaek, H Orskov, K Seyer-Hanse. Somatostatin as a tool in studies of basal carbohydrate and lipid metabolism in man: modifications of glucagon and insulin release. Scandinavian journal of clinical and laboratory investigation. vol 34. issue 4. 1975-07-24. PMID:4460228. |
somatostatin as a tool in studies of basal carbohydrate and lipid metabolism in man: modifications of glucagon and insulin release. |
1975-07-24 |
2023-08-11 |
Not clear |
| H Leblanc, J R Anderson, M B Sigel, S S Ye. Inhibitory action of somatostatin on pancreatic alpha and beta cell function. The Journal of clinical endocrinology and metabolism. vol 40. issue 4. 1975-07-23. PMID:1092707. |
these events were attended by a marked retardation of the glucose disappearance rate (k) which exhibited two clearly separable components; the initial slow component (mean k equals 0.64) coincided with the period of insulin suppression and was followed by a faster component (mean k equals 1.37) temporally related to the marked rebound increase in insulin release after discontinuation of the somatostatin infusion. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, J R Anderson, M B Sigel, S S Ye. Inhibitory action of somatostatin on pancreatic alpha and beta cell function. The Journal of clinical endocrinology and metabolism. vol 40. issue 4. 1975-07-23. PMID:1092707. |
similarly, the addition of somatostatin infusion completely blocked the release of insulin and growth hormone and delayed the release of glucagon stimulated by arginine infusion. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, J R Anderson, M B Sigel, S S Ye. Inhibitory action of somatostatin on pancreatic alpha and beta cell function. The Journal of clinical endocrinology and metabolism. vol 40. issue 4. 1975-07-23. PMID:1092707. |
following the somatostatin infusion there was a small rise in gh and a marked rebound for insulin and this was associated with a higher level of plasma glucose than that found following arginine infusion alone. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, J R Anderson, M B Sigel, S S Ye. Inhibitory action of somatostatin on pancreatic alpha and beta cell function. The Journal of clinical endocrinology and metabolism. vol 40. issue 4. 1975-07-23. PMID:1092707. |
these data establish that the administration of somatostatin can effectively block the release of insulin stimulated by arginine and glucose, can attenuate the release of glucagon induced by arginine and can enhance the glucose-mediated glucagon suppression. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, S S Ye. Comparison of cylic and linear forms of somatostatin in the inhibiton of growth hormone, insulin and glucagon Secretion. The Journal of clinical endocrinology and metabolism. vol 40. issue 5. 1975-07-23. PMID:1127098. |
comparison of cylic and linear forms of somatostatin in the inhibiton of growth hormone, insulin and glucagon secretion. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, S S Ye. Comparison of cylic and linear forms of somatostatin in the inhibiton of growth hormone, insulin and glucagon Secretion. The Journal of clinical endocrinology and metabolism. vol 40. issue 5. 1975-07-23. PMID:1127098. |
the relative potency of cyclic and linear somatostatin in their inhibitory action on gh, insulin and glucagon secretion was assessed in 7 normal adult men. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, S S Ye. Comparison of cylic and linear forms of somatostatin in the inhibiton of growth hormone, insulin and glucagon Secretion. The Journal of clinical endocrinology and metabolism. vol 40. issue 5. 1975-07-23. PMID:1127098. |
administration of linear or cyclic somatostatin as a single intravenous bolus (50 mug) resulted in a prompt and concomitant decline in both insulin and glucagon. |
1975-07-23 |
2023-08-11 |
Not clear |
| H Leblanc, S S Ye. Comparison of cylic and linear forms of somatostatin in the inhibiton of growth hormone, insulin and glucagon Secretion. The Journal of clinical endocrinology and metabolism. vol 40. issue 5. 1975-07-23. PMID:1127098. |
both the linear and cyclic form of somatostatin appears to be more potent in the inhibition of insulin than glucagon. |
1975-07-23 |
2023-08-11 |
Not clear |
| J Tamarit, J Tamarit-Rodríguez, R Goberna, M Luca. Inhibition of insulin secretion in vitro by somatostatin. Revista espanola de fisiologia. vol 30. issue 4. 1975-06-26. PMID:4456484. |
inhibition of insulin secretion in vitro by somatostatin. |
1975-06-26 |
2023-08-11 |
Not clear |
| E W Chideckel, J Palmer, D J Koerker, J Ensinck, M B Davidson, C J Goodne. Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis. The Journal of clinical investigation. vol 55. issue 4. 1975-06-18. PMID:804491. |
the nature and extent of somatostatin-induced inhibition of pancreatic endocrine secretion were studied by administration of a number of stimuli of either glucagon or insulin to over night fasted baboons with and without an infusion of linear somatostatin. |
1975-06-18 |
2023-08-11 |
rat |
| E W Chideckel, J Palmer, D J Koerker, J Ensinck, M B Davidson, C J Goodne. Somatostatin blockade of acute and chronic stimuli of the endocrine pancreas and the consequences of this blockade on glucose homeostasis. The Journal of clinical investigation. vol 55. issue 4. 1975-06-18. PMID:804491. |
when given 15 min after the start of a somatostatin infusion, these agents were essentially unable to stimulate insulin secretion. |
1975-06-18 |
2023-08-11 |
rat |