| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| G Boden, C A Baile, C L McLaughlin, F M Matschinsk. Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. The American journal of physiology. vol 241. issue 3. 1981-11-18. PMID:6116433. |
effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. |
1981-11-18 |
2023-08-12 |
rat |
| G Boden, C A Baile, C L McLaughlin, F M Matschinsk. Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. The American journal of physiology. vol 241. issue 3. 1981-11-18. PMID:6116433. |
we have studied the effects of starvation and of obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system in fed and 3- and 5-day fasted holtzman rats and in obese (fa/fa) and lean (fa/?) |
1981-11-18 |
2023-08-12 |
rat |
| G Boden, C A Baile, C L McLaughlin, F M Matschinsk. Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. The American journal of physiology. vol 241. issue 3. 1981-11-18. PMID:6116433. |
these data show that fasting decreases and obesity increases both somatostatin and insulin release. |
1981-11-18 |
2023-08-12 |
rat |
| G Boden, C A Baile, C L McLaughlin, F M Matschinsk. Effects of starvation and obesity on somatostatin, insulin, and glucagon release from an isolated perfused organ system. The American journal of physiology. vol 241. issue 3. 1981-11-18. PMID:6116433. |
they suggest that altered stimulation by nutrients was primarily responsible for changes in somatostatin and insulin release observed in starving and obese rats. |
1981-11-18 |
2023-08-12 |
rat |
| J C Prieto, J M Guerrero, C de Miguel, R Gobern. Interaction of vasoactive intestinal peptide with a cell line (HeLa) derived from human carcinoma of the cervix: binding to specific sites and stimulation of adenylate cyclase. Molecular and cellular biochemistry. vol 37. issue 3. 1981-11-18. PMID:6268963. |
secretin is eight times less potent than vip in competing with 125i vip but glucagon, insulin and somatostatin are inactive. |
1981-11-18 |
2023-08-12 |
human |
| J C Prieto, J M Guerrero, C de Miguel, R Gobern. Interaction of vasoactive intestinal peptide with a cell line (HeLa) derived from human carcinoma of the cervix: binding to specific sites and stimulation of adenylate cyclase. Molecular and cellular biochemistry. vol 37. issue 3. 1981-11-18. PMID:6268963. |
glucagon, insulin and somatostatin do not show any effect. |
1981-11-18 |
2023-08-12 |
human |
| J Knudtzo. Thyrotropin-releasing hormone increases plasma levels of glucagon, insulin, glucose and free fatty acids in rabbits. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 7. 1981-11-18. PMID:6792023. |
the increase of plasma levels of glucagon was augmented by simultaneous injection of trh and insulin, and was suppressed in rabbits which were fed or infused with somatostatin. |
1981-11-18 |
2023-08-12 |
rat |
| D Rouiller, V Schusdziarra, R H Unge. Insulin inhibits somatostatin-like immunoreactivity release stimulated by intragastric HCl. Diabetes. vol 30. issue 9. 1981-10-25. PMID:6114888. |
to determine the effect of an increase in insulin levels within the range occurring under physiologic conditions on the protein- and acid-induced release of splanchnic somatostatin, insulin was infused in dogs for 1 h following the intragastric instillation of a neutral protein load (20% liver extract at ph 7), a weak stimulus of somatostatin-like immunoreactivity (sli), and after an intragastric hcl, a strong stimulus of sli release, instilled 30 min later. |
1981-10-25 |
2023-08-12 |
Not clear |
| J L Selam, D Chenon, T C Pham, J P Gagnol, C Sany, N Thomas, G Gravagne, A Orsetti, J Mirouz. Effects of somatostatin added to insulin in a glucose-controlled insulin infusion system. Diabetologia. vol 21. issue 2. 1981-10-25. PMID:6114891. |
effects of somatostatin added to insulin in a glucose-controlled insulin infusion system. |
1981-10-25 |
2023-08-12 |
Not clear |
| J L Selam, D Chenon, T C Pham, J P Gagnol, C Sany, N Thomas, G Gravagne, A Orsetti, J Mirouz. Effects of somatostatin added to insulin in a glucose-controlled insulin infusion system. Diabetologia. vol 21. issue 2. 1981-10-25. PMID:6114891. |
a standard 400 kcal breakfast with 25 g xylose was given at 0800 h. when the blood glucose rose above 4.1 mmol/l, an external artificial pancreas was used to infuse either extra insulin (day ins) or somatostatin for either 3h (day som) or the entire 8h experimental period (day som). |
1981-10-25 |
2023-08-12 |
Not clear |
| J L Selam, D Chenon, T C Pham, J P Gagnol, C Sany, N Thomas, G Gravagne, A Orsetti, J Mirouz. Effects of somatostatin added to insulin in a glucose-controlled insulin infusion system. Diabetologia. vol 21. issue 2. 1981-10-25. PMID:6114891. |
thus somatostatin, when added to an optimal insulin infusion, minimised the insulin requirements by slowing intestinal absorption, but led to rebound hyperglycaemia if not feed-back controlled. |
1981-10-25 |
2023-08-12 |
Not clear |
| J Stachura, W J Krause, K J Ive. Endocrine cells in human cardial glands. Folia histochemica et cytochemica. vol 19. issue 1. 1981-10-25. PMID:7262703. |
immunohistochemical examinations were performed using antibodies to gastrin, glucagon, somatostatin, vip, secretin, motilin, pancreatic polypeptide, insulin and substance pl studies were performed simultaneously on human pancreatic, pyloric and duodenal tissue. |
1981-10-25 |
2023-08-12 |
human |
| P Bratusch-Marrain, H Vierhapper, B Grubeck-Loebenstein, W Waldhäusl, P Nowotn. Antidiabetic action of somatostatin after oral glucose loading: due to suppression of glucagon and growth hormone or of intestinal carbohydrate absorption? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114914. |
to elucidate the mechanism by which somatostatin lowers blood glucose concentration and insulin requirement following carbohydrate ingestion in insulin dependent diabetic patients (iddm; n = 6), the amount of insulin required for the assimilation of a 50 g glucose load was determined by means of an automated glucose-controlled insulin infusion system with and without concomitant somatostatin infusion. |
1981-10-14 |
2023-08-12 |
Not clear |
| P Bratusch-Marrain, H Vierhapper, B Grubeck-Loebenstein, W Waldhäusl, P Nowotn. Antidiabetic action of somatostatin after oral glucose loading: due to suppression of glucagon and growth hormone or of intestinal carbohydrate absorption? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114914. |
during the 3 hour period following glucose loading plasma concentrations of glucagon and growth hormone were diminished by somatostatin, as were the rise in blood glucose and insulin requirement (4.0 +/- 1.2 u) when compared with the control study (11.3 +/- 1.5 u; p less than 0.01). |
1981-10-14 |
2023-08-12 |
Not clear |
| P Bratusch-Marrain, H Vierhapper, B Grubeck-Loebenstein, W Waldhäusl, P Nowotn. Antidiabetic action of somatostatin after oral glucose loading: due to suppression of glucagon and growth hormone or of intestinal carbohydrate absorption? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114914. |
with cessation of somatostatin blood glucose levels and insulin requirement rose during the following 2 hour observation period (7.5 +/- 1.2 u) but remained basal during the control study (0.7 +/- 0.6 u; p less than 0.0005). |
1981-10-14 |
2023-08-12 |
Not clear |
| P Bratusch-Marrain, H Vierhapper, B Grubeck-Loebenstein, W Waldhäusl, P Nowotn. Antidiabetic action of somatostatin after oral glucose loading: due to suppression of glucagon and growth hormone or of intestinal carbohydrate absorption? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114914. |
thus the integrated amounts of insulin required for glucose hormone were temporarily suppressed by somatostatin. |
1981-10-14 |
2023-08-12 |
Not clear |
| P Bratusch-Marrain, H Vierhapper, B Grubeck-Loebenstein, W Waldhäusl, P Nowotn. Antidiabetic action of somatostatin after oral glucose loading: due to suppression of glucagon and growth hormone or of intestinal carbohydrate absorption? Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114914. |
it is concluded that the diminished insulin requirement and delayed rise in blood glucose during somatostatin administration after an oral glucose load is not due to its "antidiabetic" action by suppressing glucagon and growth hormone release. |
1981-10-14 |
2023-08-12 |
Not clear |
| A V Greco, G Ghirlanda, L Altomonte, R Manna, A G Rebuzzi, A Bertol. Somatostatin and insulin infusion in the management of diabetic ketoacidosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114915. |
somatostatin and insulin infusion in the management of diabetic ketoacidosis. |
1981-10-14 |
2023-08-12 |
Not clear |
| A V Greco, G Ghirlanda, L Altomonte, R Manna, A G Rebuzzi, A Bertol. Somatostatin and insulin infusion in the management of diabetic ketoacidosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114915. |
during insulin plus somatostatin infusion in 7 patients, blood glucose levels returned to normal within 4 hours and acidosis was reduced within 3 hours. |
1981-10-14 |
2023-08-12 |
Not clear |
| A V Greco, G Ghirlanda, L Altomonte, R Manna, A G Rebuzzi, A Bertol. Somatostatin and insulin infusion in the management of diabetic ketoacidosis. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 6. 1981-10-14. PMID:6114915. |
the data presented show that addition of somatostatin to treatment with low doses of insulin reduces and resolves acidosis in a shorter time while plasma levels of glucagon and gh were concomitantly reduced. |
1981-10-14 |
2023-08-12 |
Not clear |