| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
the concomittant release of insulin and somatostatin was studied in the perfused pancreas in order to assess a possible influence by somatostatin on the dose-response pattern for gip-induced insulin release. |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
in this preparation 1.0 to 10 nmol/l of gip stimulated insulin and somatostatin secretion; however while these concentrations were equipotent on insulin release, 10 nmol/l of gip stimulated somatostatin release more than 1 nmol/l, indicating differences in dose-response curves for the gip-induced stimulation of the two hormones. |
1982-06-21 |
2023-08-12 |
rat |
| b' J Szec\\xc3\\xb3wka, V Grill, E Sandberg, S Efendi\\xc4\\x8. Effect of GIP on the secretion of insulin and somatostatin and the accumulation of cyclic AMP in vitro in the rat. Acta endocrinologica. vol 99. issue 3. 1982-06-21. PMID:6122321.' |
it is concluded that 1) modulation of gip-induced insulin release is coupled to changes in cyclc amp response in the islet, 2) gip-induced somatostatin secretion may influence the concomittant insulin response. |
1982-06-21 |
2023-08-12 |
rat |
| W B Rhoten, C E Hal. An immunocytochemical study of the cytogenesis of pancreatic endocrine cells in the lizard, Anolis carolinensis. The American journal of anatomy. vol 163. issue 2. 1982-06-21. PMID:7041604. |
all four hormones searched for, insulin, glucagon, somatostatin, and pancreatic polypeptide (pp), were present in epithelioid cells shortly after oviposition. |
1982-06-21 |
2023-08-12 |
Not clear |
| T N Barry, T R Manley, C Redekopp, S R Davis, R J Fairclough, K R Lapwoo. Protein metabolism in growing lambs given fresh ryegrass (Lolium perenne)--clover (Trifolium repens) pasture ad lib. 2. Endocrine changes, glucose production, and their relationship to protein deposition and the partition of absorbed nutrients. The British journal of nutrition. vol 47. issue 2. 1982-06-21. PMID:7066291. |
protein infusion increased plasma concentrations of insulin, glucagon and thyroxine (t4), depressed those of growth hormone, prolactin and somatostatin and had no effect on triiodothyronine (t3) concentrations. |
1982-06-21 |
2023-08-12 |
Not clear |
| E Ferrannini, R A DeFronzo, R S Sherwi. Transient hepatic response to glucagon in man: role of insulin and hyperglycemia. The American journal of physiology. vol 242. issue 2. 1982-05-21. PMID:7039338. |
kg-1) while maintaining euglycemia or b) plasma glucose (+25 mg/100 ml) while blocking insulin release with somatostatin. |
1982-05-21 |
2023-08-12 |
Not clear |
| A D Cherrington, P E Williams, N Abou-Mourad, W W Lacy, K E Steiner, J E Liljenquis. Insulin as a mediator of hepatic glucose uptake in the conscious dog. The American journal of physiology. vol 242. issue 2. 1982-05-21. PMID:7039339. |
to accomplish this, the plasma glucose level was doubled by glucose infusion into 36-h fasted dogs maintained on somatostatin, basal glucagon, and basal or elevated intraportal insulin infusions. |
1982-05-21 |
2023-08-12 |
dog |
| L E Dardi, V A Memoli, V E Goul. Neuroendocrine differentiation in basal cell carcinomas. Journal of cutaneous pathology. vol 8. issue 5. 1982-05-12. PMID:6120964. |
these were studied using the immunoperoxidase technique for tissue localization of calcitonin, insulin, glucagon, somatostatin, acth, gastrin and nerve growth factor. |
1982-05-12 |
2023-08-12 |
Not clear |
| b' F Fallucca, G Delle Fave, L Giangrande, P Del Balzo, L De Magistris, R Carrat\\xc3\\xb. Effect of somatostatin on gastrin, insulin and glucagon secretion in two patients with Zollinger-Ellison syndrome. Journal of endocrinological investigation. vol 4. issue 4. 1982-05-12. PMID:6120969.' |
effect of somatostatin on gastrin, insulin and glucagon secretion in two patients with zollinger-ellison syndrome. |
1982-05-12 |
2023-08-12 |
Not clear |
| I G Banks, J M Sloan, K D Buchana. A histological study of intrasplenic transplanted neonatal rat pancreas and of adjacent adipose tissue proliferation. Diabetologia. vol 22. issue 2. 1982-05-12. PMID:7037513. |
immunohistochemistry demonstrated the presence of insulin, glucagon, somatostatin and pancreatic polypeptide within islet cells in long term grafts. |
1982-05-12 |
2023-08-12 |
rat |
| B Hansen, A Lernmark, J H Nielsen, D Owerbach, B Welinde. New approaches to therapy and diagnosis of diabetes. Diabetologia. vol 22. issue 2. 1982-05-12. PMID:7037514. |
already a number of hormones including somatostatin, human growth hormone and human insulin [4] have been produced by these new methods. |
1982-05-12 |
2023-08-12 |
human |
| R Pujol-Borrell, E L Khoury, G F Bottazz. Islet cell surface antibodies in type 1 (insulin-dependent) diabetes mellitus: use of human fetal pancreas cultures as substrate. Diabetologia. vol 22. issue 2. 1982-05-12. PMID:7037515. |
the four-layer double immunofluorescence technique showed that the surface antibody stained insulin secreting cells, but owing to rarity of a and d cells in the fetal cultures it has not yet been possible to exclude the reactivity of islet cell surface antibodies with glucagon or somatostatin cells. |
1982-05-12 |
2023-08-12 |
human |
| S L Nissen, J M Miles, J E Gerich, M W Haymon. Regulation of alpha-ketoisocaproate binding to albumin in vivo by free fatty acids. The American journal of physiology. vol 242. issue 1. 1982-04-20. PMID:7036754. |
to determine whether increased plasma ffa concentrations alter the binding of kic to plasma proteins in vivo, five postabsorptive humans were infused with triglyceride and heparin during the simultaneous administration of somatostatin, glucagon, and insulin. |
1982-04-20 |
2023-08-12 |
cattle |
| S Nistrup Madsen, S E Christensen, A P Hansen, J Thod. Influence of somatostatin on plasma cyclic AMP and metabolic substrate responses to i.v. adrenaline and glucagon in humans. Clinical endocrinology. vol 15. issue 5. 1982-04-12. PMID:6120054. |
somatostatin suppressed the insulin response to glucagon and inhibited the insulin rebound observed on termination of adrenaline infusion. |
1982-04-12 |
2023-08-12 |
human |
| S Nistrup Madsen, S E Christensen, A P Hansen, J Thod. Influence of somatostatin on plasma cyclic AMP and metabolic substrate responses to i.v. adrenaline and glucagon in humans. Clinical endocrinology. vol 15. issue 5. 1982-04-12. PMID:6120054. |
the plasma glucose response to glucagon was exaggerated by somatostatin, reflecting insulin deficiency. |
1982-04-12 |
2023-08-12 |
human |
| B J Frankel, A M Heldt, G M Grodsk. Effects of K+ and arginine on insulin, glucagon, and somatostatin release from the in vitro perfused rat pancreas. Endocrinology. vol 110. issue 2. 1982-04-12. PMID:6120069. |
effects of k+ and arginine on insulin, glucagon, and somatostatin release from the in vitro perfused rat pancreas. |
1982-04-12 |
2023-08-12 |
rat |
| K Kawai, L Orci, R H Unge. High somatostatin uptake by the isolated perfused dog pancreas consistent with "insulo-acinar" axis. Endocrinology. vol 110. issue 2. 1982-04-12. PMID:6120073. |
the canine pancreas takes up 50-80% of somatostatin perfused over a concentration range of 20 to 4000 pg/ml, compared to less than 21% of insulin or glucagon. |
1982-04-12 |
2023-08-12 |
dog |
| H Taniguchi, K Murakami, A Tsutou, M Tamagawa, K Ejiri, M Yoshioka, T Kobayashi, K Terashi, N Kobayashi, M Utsumi, S Morita, S Bab. A role of endogenous somatostatin and glucagon in insulin release from pancreatic islets. The Kobe journal of medical sciences. vol 27. issue 6. 1982-03-26. PMID:6119394. |
a role of endogenous somatostatin and glucagon in insulin release from pancreatic islets. |
1982-03-26 |
2023-08-12 |
Not clear |
| E L Lien, V M Garsk. Route of administration as a factor in the selectivity of hormone suppression of a somatostatin analog in rats. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 12. 1982-03-22. PMID:6119282. |
the method of administration of [d-ala5,d-trp8] somatostatin is of central importance in determining the degree and duration of suppression of insulin and glucagon release. |
1982-03-22 |
2023-08-12 |
rat |
| A Aynsley-Green, N D Barnes, T E Adrian, J Kingston, S Boyes, S R Bloo. Effect of somatostatin infusion on intermediary metabolism and entero-insular hormone release in infants with hyperinsulinaemic hypoglycaemia. Acta paediatrica Scandinavica. vol 70. issue 6. 1982-03-22. PMID:6119871. |
the use of somatostatin has been advocated recently in such infants because of its effect on inhibiting insulin release, but nothing is known of the wider effects of this potent hormone in the young child. |
1982-03-22 |
2023-08-12 |
Not clear |