| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| K P Ratzmann, W Besch, S Witt, B Schul. Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance. Diabetologia. vol 21. issue 3. 1982-01-20. PMID:6117492. |
insulin resistance was studied in seven non-obese male subjects with impaired glucose tolerance and four healthy, age and body-weight matched male control subjects by means of a continuous intravenous infusion of somatostatin, glucose and insulin over 150 min. |
1982-01-20 |
2023-08-12 |
human |
| K P Ratzmann, W Besch, S Witt, B Schul. Evaluation of insulin resistance during inhibition of endogenous insulin and glucagon secretion by somatostatin in non-obese subjects with impaired glucose tolerance. Diabetologia. vol 21. issue 3. 1982-01-20. PMID:6117492. |
endogenous insulin (c-peptide), growth hormone, and glucagon secretion were suppressed by somatostatin in both groups. |
1982-01-20 |
2023-08-12 |
human |
| R E Weiss, A H Reddi, M E Nimn. Somatostatin can locally inhibit proliferation and differentiation of cartilage and bone precursor cells. Calcified tissue international. vol 33. issue 4. 1982-01-09. PMID:6117356. |
concurrent injections of insulin and somatostatin obliterated the inhibitory effect of the latter on cell proliferation. |
1982-01-09 |
2023-08-12 |
Not clear |
| R E Weiss, A H Reddi, M E Nimn. Somatostatin can locally inhibit proliferation and differentiation of cartilage and bone precursor cells. Calcified tissue international. vol 33. issue 4. 1982-01-09. PMID:6117356. |
somatostatin can locally regulate the proliferation and differentiation of chondroprogenitor and osteoprogenitor cells in vivo and may directly contribute to the regulation of bone growth by its ability to counteract the stimulatory effect of insulin. |
1982-01-09 |
2023-08-12 |
Not clear |
| J E Liljenquist, G L Mueller, A D Cherrington, J M Perry, D Rabi. Retardant effect of hyperglycemia on the rise in plasma fatty acids following insulin withdrawal in man. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 13. issue 10. 1982-01-09. PMID:6117512. |
when somatostatin was infused with hyperglycemia maintained at approximately 230 mg/dl, plasma insulin levels were again maintained at levels 4 uu/ml. |
1982-01-09 |
2023-08-12 |
Not clear |
| P U Heitz, G Klöppel, J M Polak, J J Stau. Ectopic hormone production by endocrine tumors: localization of hormones at the cellular level by immunocytochemistry. Cancer. vol 48. issue 9. 1982-01-09. PMID:6271390. |
the unlabeled antibody enzyme method was used for the detection of insulin, glucagon, somatostatin, pancreatic polypeptide, corticotropin, beta-lipotropin, calcitonin, parathyroid hormone, and gastrin. |
1982-01-09 |
2023-08-12 |
Not clear |
| R F Santerre, R A Cook, R M Crisel, J D Sharp, R J Schmidt, D C Williams, C P Wilso. Insulin synthesis in a clonal cell line of simian virus 40-transformed hamster pancreatic beta cells. Proceedings of the National Academy of Sciences of the United States of America. vol 78. issue 7. 1981-12-21. PMID:6270673. |
somatostatin and dexamethasone markedly inhibited hit insulin secretion. |
1981-12-21 |
2023-08-12 |
Not clear |
| J Rahier, J Wallon, J C Henqui. Cell populations in the endocrine pancreas of human neonates and infants. Diabetologia. vol 20. issue 5. 1981-12-16. PMID:6116638. |
with age, the proportion of somatostatin cells decreased (from about 30% in neonates to about 10% in adults), that of insulin cells increased (50 to 70%) and that of glucagon cells remained stable (20%). |
1981-12-16 |
2023-08-12 |
human |
| M Reineck. Immunohistochemical localization of polypeptide hormones in endocrine cells of the digestive tract of Branchiostoma lanceolatum. Cell and tissue research. vol 219. issue 3. 1981-11-24. PMID:7023687. |
positive reactions were obtained with antisera against the four mammalian islet hormones (insulin, glucagon, pancreatic polypeptide, somatostatin) and against secretin, vasoactive intestinal polypeptide, pentagastrin and neurotensin. |
1981-11-24 |
2023-08-12 |
Not clear |
| J D Best, G J Taborsky, J B Halter, D Port. Glucose disposal is not proportional to plasma glucose level in man. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6115785. |
to test this assumption, the relationship between glucose concentration and disposal rate was studied in man during infusion of somatostatin +/- exogenous insulin to achieve fixed plasma insulin levels of 1, 18, and 46 microm/ml on separate days. |
1981-11-22 |
2023-08-12 |
Not clear |
| J Bringer, J Mirouze, G Marchal, T C Pham, A Luyckx, P Lefebvre, A Orsett. Glucagon immunoreactivity and antidiabetic action of somatostatin in the totally duodeno-pancreatectomized and gastrectomized human. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6115786. |
the effects of somatostatin on spontaneous hyperglycemia, plasma growth hormone, and irg after withdrawal of insulin treatment was studied in 4 patients. |
1981-11-22 |
2023-08-12 |
human |
| J Bringer, J Mirouze, G Marchal, T C Pham, A Luyckx, P Lefebvre, A Orsett. Glucagon immunoreactivity and antidiabetic action of somatostatin in the totally duodeno-pancreatectomized and gastrectomized human. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6115786. |
somatostatin blunted both the hyperglycemic and paradoxical irg responses to the glucose challenge, and reduced the spontaneous rise of blood glucose that occurred after insulin withdrawal. |
1981-11-22 |
2023-08-12 |
human |
| J Bringer, J Mirouze, G Marchal, T C Pham, A Luyckx, P Lefebvre, A Orsett. Glucagon immunoreactivity and antidiabetic action of somatostatin in the totally duodeno-pancreatectomized and gastrectomized human. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6115786. |
in contrast, the inhibition by somatostatin of the rise in blood glucose which occurs after insulin withdrawal does not seem to be mediated through irg or growth hormone. |
1981-11-22 |
2023-08-12 |
human |
| A Dorn, H G Bernstein, H J Hahn, G Kostmann, M Ziegle. [Immunohistochemical evidence of some peptidohormones in the central nervous system of normoglycemic and hyperglycemic rodents (author's transl)]. Zeitschrift fur mikroskopisch-anatomische Forschung. vol 95. issue 3. 1981-11-22. PMID:6116366. |
the content and the distribution of insulin, glucagon and somatostatin were studied in normoglycemic and hyperglycemic rodents by immunohistochemical techniques. |
1981-11-22 |
2023-08-12 |
Not clear |
| E R Trimble, P P Gerber, A E Renol. Abnormalities of pancreatic somatostatin secretion corrected by in vivo insulin treatment of streptozotocin-diabetic rats. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6168508. |
abnormalities of pancreatic somatostatin secretion corrected by in vivo insulin treatment of streptozotocin-diabetic rats. |
1981-11-22 |
2023-08-12 |
rat |
| E R Trimble, P P Gerber, A E Renol. Abnormalities of pancreatic somatostatin secretion corrected by in vivo insulin treatment of streptozotocin-diabetic rats. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6168508. |
by contrast, in vivo insulin treatment restored the glucose sensitivity of the somatostatin secreting cells. |
1981-11-22 |
2023-08-12 |
rat |
| E R Trimble, P P Gerber, A E Renol. Abnormalities of pancreatic somatostatin secretion corrected by in vivo insulin treatment of streptozotocin-diabetic rats. Diabetes. vol 30. issue 10. 1981-11-22. PMID:6168508. |
in addition, in vivo insulin treatment resulted in a lowering of the high basal somatostatin secretion rate found in islets from untreated diabetic rats. |
1981-11-22 |
2023-08-12 |
rat |
| M El-Salhy, L Grimeliu. Histological and immunohistochemical studies of the endocrine pancreas of lizards. Histochemistry. vol 72. issue 2. 1981-11-22. PMID:6168610. |
in both species in b, a and d cells could be detected by their cross-reactivity with antisera raised against mammalian insulin, glucagon and somatostatin. |
1981-11-22 |
2023-08-12 |
Not clear |
| Y Minaire, J Forichon, M J Jomain, G Dalleve. Independence of circulating insulin levels of the increased glucose turnover in shivering dogs. Experientia. vol 37. issue 7. 1981-11-18. PMID:6115762. |
in dogs, selective insulin deficiency induced by simultaneous somatostatin and glucagon infusion does not alter the high rate of glucose utilization provoked by acute cold exposure. |
1981-11-18 |
2023-08-12 |
Not clear |
| O Ljungberg, G Järnerot, P Rolny, G Wickbo. Human pancreatic polypeptide (HPP) immunoreactivity in an infiltrating endocrine tumour of the papilla of Vater with unusual morphology. Virchows Archiv. A, Pathological anatomy and histology. vol 392. issue 1. 1981-11-18. PMID:6116310. |
no reaction was found with antibodies against gastrin, insulin, glucagon, vasoactive intestinal polypeptide or somatostatin. |
1981-11-18 |
2023-08-12 |
human |