| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| R R Wolfe, J H Sha. Inhibitory effect of plasma free fatty acids on glucose production in the conscious dog. The American journal of physiology. vol 246. issue 2 Pt 1. 1984-03-16. PMID:6141738. |
glucose production was measured by means of the primed-constant infusion of [6-3h]- and/or [u-14c]glucose, and insulin and glucagon were clamped at constant levels by means of the infusion of somatostatin, insulin, and glucagon. |
1984-03-16 |
2023-08-12 |
dog |
| W K Ward, J D Best, J B Halter, D Port. Prolonged infusion of somatostatin with glucagon replacement increases plasma glucose and glucose turnover in man. The Journal of clinical endocrinology and metabolism. vol 58. issue 3. 1984-03-12. PMID:6141177. |
we conclude that prolonged mild selective insulin deficiency produced by infusion of somatostatin with glucagon replacement in normal men causes an elevation of the fasting plasma glucose level, which is maintained by glucose overproduction rather than by glucose underutilization. |
1984-03-12 |
2023-08-12 |
Not clear |
| P R Bratusch-Marrain, W K Waldhäusl, S Gasić, A Hofe. Hepatic disposal of biosynthetic human insulin and porcine C-peptide in humans. Metabolism: clinical and experimental. vol 33. issue 2. 1984-03-07. PMID:6141519. |
the output of c-peptide from the splanchnic bed was reduced by somatostatin by about 90%, indicating that endogenous insulin production only minimally contributed to total insulin levels achieved during infusion of exogenous human insulin. |
1984-03-07 |
2023-08-12 |
human |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
magnesium requirement for somatostatin inhibition of insulin secretion. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
we observed that in the absence of magnesium, somatostatin concentrations of 0.5 and 2.0 ng/ml were without effect on first phase insulin secretion. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
however, these same somatostatin levels produced 50% or more inhibition of insulin secretion in the presence of magnesium at 0.3 or 0.6 meq/l. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
similarly, in the absence of magnesium, somatostatin at 50 ng/ml failed to inhibit second phase insulin secretion, whereas this same somatostatin level produced about 50% inhibition of insulin secretion in the presence of magnesium at 0.3 meq/l. |
1984-03-02 |
2023-08-12 |
rat |
| S J Bhathena, S Awoke, N R Voyles, S D Wilkins, L Recant, H K Oie, A F Gazda. Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 175. issue 1. 1984-02-28. PMID:6141566. |
insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones. |
1984-02-28 |
2023-08-12 |
rat |
| S J Bhathena, S Awoke, N R Voyles, S D Wilkins, L Recant, H K Oie, A F Gazda. Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 175. issue 1. 1984-02-28. PMID:6141566. |
cells derived from rat islet tumor and grown in culture (parent cells-rin-m) and two clones obtained from them were used to study the effect of various secretagogues on insulin, glucagon, and somatostatin secretion. |
1984-02-28 |
2023-08-12 |
rat |
| S J Bhathena, S Awoke, N R Voyles, S D Wilkins, L Recant, H K Oie, A F Gazda. Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 175. issue 1. 1984-02-28. PMID:6141566. |
parent cells secreted all three hormones in various quantities, while clone 5f secreted predominantly insulin and clone 14b secreted predominantly somatostatin. |
1984-02-28 |
2023-08-12 |
rat |
| S J Bhathena, S Awoke, N R Voyles, S D Wilkins, L Recant, H K Oie, A F Gazda. Insulin, glucagon, and somatostatin secretion by cultured rat islet cell tumor and its clones. Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.). vol 175. issue 1. 1984-02-28. PMID:6141566. |
somatostatin secretion was stimulated in clone 14b by arginine, tolbutamide, theophylline, and insulin. |
1984-02-28 |
2023-08-12 |
rat |
| Z D Goodman, J Albores-Saavedra, D M Lundbla. Somatostatinoma of the cystic duct. Cancer. vol 53. issue 3. 1984-02-28. PMID:6318950. |
immunoperoxidase staining showed that the tumor cells contained somatostatin but did not contain immunoreactive acth, gastrin, calcitonin, glucagon, insulin, parathyroid hormone, or carcinoembryonic antigen. |
1984-02-28 |
2023-08-12 |
Not clear |
| Y Seino, S Seino, J Takemura, K Tsuda, S Nishi, H Ishida, M Seno, M Usami, M Ikeda, H Imur. Changes in insulin, somatostatin, and glucagon secretion during the development of obesity in ventromedial hypothalamic-lesioned rats. Endocrinology. vol 114. issue 2. 1984-02-24. PMID:6140160. |
changes in insulin, somatostatin, and glucagon secretion during the development of obesity in ventromedial hypothalamic-lesioned rats. |
1984-02-24 |
2023-08-12 |
rat |
| Y Seino, S Seino, J Takemura, K Tsuda, S Nishi, H Ishida, M Seno, M Usami, M Ikeda, H Imur. Changes in insulin, somatostatin, and glucagon secretion during the development of obesity in ventromedial hypothalamic-lesioned rats. Endocrinology. vol 114. issue 2. 1984-02-24. PMID:6140160. |
changes in insulin, somatostatin, and glucagon secretion during the development of obesity in rats after ventromedial hypothalamic (vmh) lesions were evaluated by measuring fasting hormone levels and their secretion from the isolated perfused pancreas. |
1984-02-24 |
2023-08-12 |
rat |
| Y Seino, S Seino, J Takemura, K Tsuda, S Nishi, H Ishida, M Seno, M Usami, M Ikeda, H Imur. Changes in insulin, somatostatin, and glucagon secretion during the development of obesity in ventromedial hypothalamic-lesioned rats. Endocrinology. vol 114. issue 2. 1984-02-24. PMID:6140160. |
these results show that vmh lesions result in an increased insulin and somatostatin secretion. |
1984-02-24 |
2023-08-12 |
rat |
| D J Evans, R G Hoffmann, R K Kalkhoff, A H Kisseba. Relationship of body fat topography to insulin sensitivity and metabolic profiles in premenopausal women. Metabolism: clinical and experimental. vol 33. issue 1. 1984-02-22. PMID:6361449. |
in 23 women, in vivo insulin sensitivity was also determined from the steady-state plasma glucose (sspg) level at comparable insulin levels of approximately 100 microu/ml attained by the intravenous infusion of somatostatin, glucose, and insulin. |
1984-02-22 |
2023-08-12 |
human |
| M Hoenig, D C Ferguson, F M Matschinsk. Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. Diabetes. vol 33. issue 1. 1984-02-21. PMID:6140199. |
we studied the release of insulin, glucagon, and somatostatin in response to glucose, glyceraldehyde (ga), and alpha-ketoisocaproate (kic) from rat kidneys containing transplanted insulinomas. |
1984-02-21 |
2023-08-12 |
rat |
| M Hoenig, D C Ferguson, F M Matschinsk. Fuel-induced insulin release in vitro from insulinomas transplanted into the rat kidney. Diabetes. vol 33. issue 1. 1984-02-21. PMID:6140199. |
the insulin content of the tumor-containing kidney ranged from 40 to 679 micrograms; the glucagon and somatostatin concentrations ranged from undetectable levels to 3.7 micrograms and 248 ng, respectively. |
1984-02-21 |
2023-08-12 |
rat |
| M Itoh, Y Hirooka, N Nihe. Response of plasma somatostatin-like immunoreactivity (SLI) to a 75 g oral glucose tolerance test in normal subjects and patients with impaired glucose tolerance. Acta endocrinologica. vol 104. issue 4. 1984-02-14. PMID:6140806. |
to study the role of somatostatin in the pathophysiology of glucose intolerance in man, plasma somatostatin-like immunoreactivity (sli) was measured in 8 normal subjects, 6 patients with insulin dependent diabetes mellitus (iddm), 13 with non-insulin dependent diabetes mellitus (niddm), and 9 with hyperthyroidism, by extraction of plasma sli and radioimmunoassay. |
1984-02-14 |
2023-08-12 |
human |
| G J Taborsk. Evidence of a paracrine role for pancreatic somatostatin in vivo. The American journal of physiology. vol 245. issue 6. 1984-02-14. PMID:6140853. |
to test this hypothesis directly, a nonimmunoreactive analogue of somatostatin [( d-ala5-d-trp8]ss) was infused intravenously at 0.55-17 micrograms/min into anesthetized dogs to suppress the secretion of pancreatic somatostatin and observe the effects of that suppression on glucagon and insulin release. |
1984-02-14 |
2023-08-12 |
Not clear |