| Publication |
Sentence |
Publish Date |
Extraction Date |
Species |
| A Iannucci, K Mukai, D Johnson, B Burk. Endocrine pancreas in cystic fibrosis: an immunohistochemical study. Human pathology. vol 15. issue 3. 1984-04-20. PMID:6365738. |
the pancreases of 17 patients who had cystic fibrosis with and without diabetes mellitus were evaluated at autopsy by routine staining and immunohistochemical methods for insulin, glucagon, somatostatin, and pancreatic polypeptide. |
1984-04-20 |
2023-08-12 |
Not clear |
| O D Hegre, G E Hickey, S Marshall, J R Seri. Modification of allograft immunogenicity in perinatal islets isolated and purified in vitro. Transplantation. vol 37. issue 3. 1984-04-10. PMID:6422593. |
the three major endocrine cell types of the islet were identified by immunocytochemical localization of insulin, glucagon, and somatostatin. |
1984-04-10 |
2023-08-12 |
rat |
| J M Allen, T E Adrian, J Webster, A Howe, S R Bloo. Effect of single dose of omeprazole on the gastrointestinal peptide response to food. Hepato-gastroenterology. vol 31. issue 1. 1984-04-06. PMID:6365714. |
there was no significant effect on basal or post-prandial levels of somatostatin, insulin, pancreatic glucagon, enteroglucagon, gastric inhibitory polypeptide, pancreatic polypeptide, motilin, neurotensin, cholecystokinin, secretin, vasoactive intestinal peptide and gastrin-releasing peptide or blood glucose concentration. |
1984-04-06 |
2023-08-12 |
human |
| S G Rosen, W E Clutter, M A Berk, S D Shah, P E Crye. Epinephrine supports the postabsorptive plasma glucose concentration and prevents hypoglycemia when glucagon secretion is deficient in man. The Journal of clinical investigation. vol 73. issue 2. 1984-04-04. PMID:6142057. |
accordingly, we assessed the impact of glucagon deficiency, produced by infusion of somatostatin with insulin, without and with pharmacologic alpha- and beta-adrenergic blockade on the postabsorptive plasma glucose concentration and glucose kinetics in normal human subjects. |
1984-04-04 |
2023-08-12 |
human |
| S G Rosen, W E Clutter, M A Berk, S D Shah, P E Crye. Epinephrine supports the postabsorptive plasma glucose concentration and prevents hypoglycemia when glucagon secretion is deficient in man. The Journal of clinical investigation. vol 73. issue 2. 1984-04-04. PMID:6142057. |
during somatostatin with insulin alone mean glucose production fell from 1.5 +/- 0.05 to 0.7 +/- 0.2 mg/kg per min and mean plasma glucose declined from 93 +/- 3 to 67 +/- 4 mg/dl over 1 h; glucose production then increased to base-line rates and plasma glucose plateaued at 64-67 mg/dl over 2 h. this plateau was associated with, and is best attributed to, an eightfold increase in mean plasma epinephrine. |
1984-04-04 |
2023-08-12 |
human |
| S G Rosen, W E Clutter, M A Berk, S D Shah, P E Crye. Epinephrine supports the postabsorptive plasma glucose concentration and prevents hypoglycemia when glucagon secretion is deficient in man. The Journal of clinical investigation. vol 73. issue 2. 1984-04-04. PMID:6142057. |
it did not occur when adrenergic blockade was added; glucose production remained low and mean plasma glucose declined progressively to a hypoglycemic level of 45 +/- 4 mg/dl, significantly (p less than 0.001) lower than the final value during somatostatin with insulin alone. |
1984-04-04 |
2023-08-12 |
human |
| T Tomita, P Visser, S Friesen, V Doul. Cortisone-induced islet cell hyperplasia in hamsters. Virchows Archiv. B, Cell pathology including molecular pathology. vol 45. issue 1. 1984-04-02. PMID:6142561. |
measurement of serum glucose and insulin; pancreatic insulin, glucagon, somatostatin, pancreatic polypeptide as well as islet tissue morphometry were performed. |
1984-04-02 |
2023-08-12 |
Not clear |
| P Klein, W Engelhardt, M Stolte, P O Schwille, J Neidhard. Pancreatic duct occlusion in the rat - short-term effects on oral glucose tolerance and short- and long-term effects on hormone content of the pancreas. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 16. issue 1. 1984-03-30. PMID:6141943. |
in a short-term (14 days) and a long-term (84 days) experiment after pancreatic duct occlusion in the rat, we measured the insulin, glucagon and somatostatin content of the pancreas; in the short-term experiment, in addition, we performed an oral glucose tolerance test on the 14th day. |
1984-03-30 |
2023-08-12 |
rat |
| P Klein, W Engelhardt, M Stolte, P O Schwille, J Neidhard. Pancreatic duct occlusion in the rat - short-term effects on oral glucose tolerance and short- and long-term effects on hormone content of the pancreas. European surgical research. Europaische chirurgische Forschung. Recherches chirurgicales europeennes. vol 16. issue 1. 1984-03-30. PMID:6141943. |
the insulin content of the pancreas on days 14 and 84 after occlusion was increased, glucagon and somatostatin unchanged. |
1984-03-30 |
2023-08-12 |
rat |
| M Matsumura, T Fukushima, H Saito, S Sait. In vivo and in vitro effects of beta-endorphin on glucose metabolism in the rat. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 16. issue 1. 1984-03-27. PMID:6141988. |
intravenous injection of beta-ep (5 micrograms/100 g bw) into ether-anaesthetized rats resulted in prompt and sustained hyperglycaemia with increases in the plasma glucagon and somatostatin levels and decrease in the plasma insulin level. |
1984-03-27 |
2023-08-12 |
rat |
| H Yasuda, Y Harano, S Ohgaku, K Kosugi, M Suzuki, H Hidaka, A Kashiwagi, Y Shiget. Insulin sensitivity in pancreatitis, liver diseases, steroid treatment and hyperthyroidism assessed by glucose, insulin and somatostatin infusion. Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et metabolisme. vol 16. issue 1. 1984-03-27. PMID:6141989. |
insulin sensitivity in pancreatitis, liver diseases, steroid treatment and hyperthyroidism assessed by glucose, insulin and somatostatin infusion. |
1984-03-27 |
2023-08-12 |
human |
| V Schusdziarra, B Rewes, N Lenz, V Maier, E F Pfeiffe. Carbohydrates modulate opiate receptor mediated mechanisms during postprandial endocrine function. Regulatory peptides. vol 7. issue 3. 1984-03-21. PMID:6141625. |
the present data demonstrate that the addition of carbohydrates either orally or intravenously to fat and protein meals modulates the effect of endogenous opiates in the regulation of postprandial somatostatin, insulin and pancreatic polypeptide release in dogs in a way that carbohydrates induce inhibitory mechanisms that are mediated via endogenous opiate receptors. |
1984-03-21 |
2023-08-12 |
Not clear |
| H G Güllner, W W Owen, V Harris, R H Unge. Dermorphin: an opioid peptide from amphibian skin which affects endocrine pancreatic function. Archives internationales de pharmacodynamie et de therapie. vol 266. issue 1. 1984-03-19. PMID:6141770. |
we examined the effect of intravenous injection of the amphibian skin opioid heptapeptide dermorphin on plasma glucose, insulin, glucagon and somatostatin in the rat. |
1984-03-19 |
2023-08-12 |
rat |
| R R Wolfe, J H Sha. Inhibitory effect of plasma free fatty acids on glucose production in the conscious dog. The American journal of physiology. vol 246. issue 2 Pt 1. 1984-03-16. PMID:6141738. |
glucose production was measured by means of the primed-constant infusion of [6-3h]- and/or [u-14c]glucose, and insulin and glucagon were clamped at constant levels by means of the infusion of somatostatin, insulin, and glucagon. |
1984-03-16 |
2023-08-12 |
dog |
| W K Ward, J D Best, J B Halter, D Port. Prolonged infusion of somatostatin with glucagon replacement increases plasma glucose and glucose turnover in man. The Journal of clinical endocrinology and metabolism. vol 58. issue 3. 1984-03-12. PMID:6141177. |
we conclude that prolonged mild selective insulin deficiency produced by infusion of somatostatin with glucagon replacement in normal men causes an elevation of the fasting plasma glucose level, which is maintained by glucose overproduction rather than by glucose underutilization. |
1984-03-12 |
2023-08-12 |
Not clear |
| P R Bratusch-Marrain, W K Waldhäusl, S Gasić, A Hofe. Hepatic disposal of biosynthetic human insulin and porcine C-peptide in humans. Metabolism: clinical and experimental. vol 33. issue 2. 1984-03-07. PMID:6141519. |
the output of c-peptide from the splanchnic bed was reduced by somatostatin by about 90%, indicating that endogenous insulin production only minimally contributed to total insulin levels achieved during infusion of exogenous human insulin. |
1984-03-07 |
2023-08-12 |
human |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
magnesium requirement for somatostatin inhibition of insulin secretion. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
we observed that in the absence of magnesium, somatostatin concentrations of 0.5 and 2.0 ng/ml were without effect on first phase insulin secretion. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
however, these same somatostatin levels produced 50% or more inhibition of insulin secretion in the presence of magnesium at 0.3 or 0.6 meq/l. |
1984-03-02 |
2023-08-12 |
rat |
| D L Curry, L L Bennet. Magnesium requirement for somatostatin inhibition of insulin secretion. Acta endocrinologica. vol 105. issue 1. 1984-03-02. PMID:6141690. |
similarly, in the absence of magnesium, somatostatin at 50 ng/ml failed to inhibit second phase insulin secretion, whereas this same somatostatin level produced about 50% inhibition of insulin secretion in the presence of magnesium at 0.3 meq/l. |
1984-03-02 |
2023-08-12 |
rat |